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Fig. 4 | Lipids in Health and Disease

Fig. 4

From: Serum lipidomic study of long-chain fatty acids in psoriasis patients prior to and after anti-IL-17A monoclonal antibody treatment by quantitative GC‒MS analysis with in situ extraction

Fig. 4

Abnormal LCFA metabolism in IMQ-treated WT and Tcrd−/− mice. Macroscopic and histological views of the dorsal skin were taken after continuous treatment with IMQ for five days (a, b). PASI scores were identified on the days indicated on a scale from 0–12 (c). IL-17A mRNA expression in the dorsal skin of IMQ-treated WT and Tcrd−/− mice was measured (d). The total content of LCFAs (e), SFAs (f, i), MUFAs (g, j) and PUFAs (h, k) in serum samples of WT and Tcrd−/− mice was analysed. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001

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Lipids in Health and Disease

ISSN: 1476-511X