| No. Events (%) | Crude | P | Model 1 | P | Model 2 | P | Model 3 | P |
---|---|---|---|---|---|---|---|---|---|
Cardiovascular disease | Â | Â | Â | Â | Â | Â | Â | Â | |
Cum-RC | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Class 1 | 315 (14.20) | 1 | Â | 1 | Â | 1 | Â | 1 | Â |
Class 2 | 354 (11.29) | 0.76 (0.65,0.90) | 0.001 | 0.79 (0.67,0.93) | 0.004 | 0.81 (0.68,0.95) | 0.011 | 0.80 (0.68,0.95) | 0.011 |
Cum-RC | Â | Â | Â | Â | Â | Â | Â | Â | Â |
≤ 57.36 | 185 (10.32) | 1 |  | 1 |  | 1 |  | 1 |  |
57.36–87.52 | 229 (12.80) | 1.28 (1.04,1.57) | 0.021 | 1.26 (1.02,1.55) | 0.030 | 1.20 (0.97,1.47) | 0.094 | 1.18 (0.96,1.45) | 0.125 |
> 87.52 | 255 (14.24) | 1.44 (1.18,1.76) | < 0.001 | 1.45 (1.18,1.78) | < 0.001 | 1.30 (1.05,1.61) | 0.015 | 1.27 (1.02,1.58) | 0.032 |
P for trend |  | < 0.001 |  | < 0.001 |  | 0.016 |  | 0.033 |  |
Heart disease | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Cum-RC | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Class 1 | 202 (9.10) | 1 | Â | 1 | Â | 1 | Â | 1 | Â |
Class 2 | 205 (6.54) | 0.76 (0.65,0.90) | 0.001 | 0.80 (0.68,0.95) | 0.011 | 0.73 (0.60,0.90) | 0.003 | 0.75 (0.61,0.92) | 0.005 |
Cum-RC | Â | Â | Â | Â | Â | Â | Â | Â | Â |
≤ 57.36 | 117 (6.53) | 1 |  | 1 |  | 1 |  | 1 |  |
57.36–87.52 | 140 (7.83) | 1.22 (0.94,1.57) | 0.133 | 1.17 (0.91,1.51) | 0.224 | 1.13 (0.87,1.46) | 0.358 | 1.13 (0.87,1.46) | 0.370 |
> 87.52 | 150 (8.38) | 1.31 (1.02,1.68) | 0.036 | 1.25 (0.97,1.61) | 0.085 | 1.15 (0.88,1.49) | 0.307 | 1.17 (0.90,1.54) | 0.245 |
P for trend | Â | 0.037 | Â | 0.088 | Â | 0.315 | Â | 0.249 | Â |
Stroke | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Cum-RC | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Class 1 | 134 (6.04) | 1 | Â | 1 | Â | 1 | Â | 1 | Â |
Class 2 | 166 (5.30) | 0.86 (0.68,1.09) | 0.224 | 0.85 (0.67,1.09) | 0.198 | 0.89 (0.70,1.13) | 0.334 | 0.89 (0.70,1.14) | 0.359 |
Cum-RC | Â | Â | Â | Â | Â | Â | Â | Â | Â |
≤ 57.36 | 75 (4.19) | 1 |  | 1 |  | 1 |  | 1 |  |
57.36–87.52 | 101 (5.65) | 1.37 (1.01,1.86) | 0.044 | 1.39 (1.02,1.89) | 0.036 | 1.30 (0.95,1.77) | 0.098 | 1.27 (0.93,1.74) | 0.132 |
> 87.52 | 124 (6.92) | 1.70 (1.27,2.29) | < 0.001 | 1.84 (1.37,2.48) | < 0.001 | 1.61 (1.18,2.19) | 0.003 | 1.51 (1.09,2.07) | 0.012 |
P for trend |  | < 0.001 |  | < 0.001 |  | 0.003 |  | 0.012 |  |