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Fig. 2 | Lipids in Health and Disease

Fig. 2

From: A regulatory element associated to NAFLD in the promoter of DIO1 controls LDL-C, HDL-C and triglycerides in hepatic cells

Fig. 2

Relative gene expression analysis of CRISPR-Cas9 gRNA-1 and gRNA-2 mutants for candidate genes. Gene expression levels were analyzed with RT-qPCR, relative to TATA binding protein (TBP) and wildtype HepG2 (WT) as control. The values are given as means and standard deviations of the results from four biological replicates, P values derived from unpaired T-Test. *P =  < 0.05,**P =  < 0.01

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Lipids in Health and Disease

ISSN: 1476-511X