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Fig. 3 | Lipids in Health and Disease

Fig. 3

From: Topical rhubarb charcoal-crosslinked chitosan/silk fibroin sponge scaffold for the repair of diabetic ulcers improves hepatic lipid deposition in db/db mice via the AMPK signalling pathway

Fig. 3

Effects of RCS/SF scaffold on amelioration of liver injury and lipid deposition in db/db mice. A H&E staining of liver sections (up row, x 200; down row, x 400). Green arrows indicate ballooning changes, red arrows indicate lipid droplets. B Oil-Red O staining of liver sections (up row, x 200; down row, x 400). C PAS staining of liver sections (up row, x 200; down row, x 400). Blue arrows indicate glycogen granules. D NAFLD activity score (total NASH). E Relative quantification of the Oil-Red O staining area. F Relative quantification of the PAS staining area. G Hepatic TG levels. H ALT activity level of liver. I AST activity level of liver. The values reported in the figure represent the means ± SEM (n = 6). ####P < 0.0001, ###P < 0.001, ##P < 0.01 compared with the db/m group; ***P < 0.001, **P < 0.01, *P < 0.05 compared with the RC group

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Lipids in Health and Disease

ISSN: 1476-511X