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Fig. 1 | Lipids in Health and Disease

Fig. 1

From: Bidirectional two-sample mendelian randomization analysis identifies causal associations of MRI-based cortical thickness and surface area relation to NAFLD

Fig. 1

The flowchart of the Mendelian Randomization (MR) study. Based on mendelian assumption 1, NAFLD, liver fat and liver volume are significantly related to genetic instrumental variables (IVs). Assumption 2 proposes that these IVs do not influence outcomes via confounding variables. Assumption 3 asserts that the genetic IVs do not directly impact the structure of cortex but exert influence only through indirect exposure

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Lipids in Health and Disease

ISSN: 1476-511X