Association of triglyceride glucose-body mass index and hemoglobin glycation index with heart failure prevalence in hypertensive populations: a study across different glucose metabolism status

Table 4 Combined association of TyG-BMI and HGI with risk of HF in hypertensive population stratified by diabetic status

	Age-standardized prevalence, %	Age adjusted^a		Multivariate adjusted^b
	Age-standardized prevalence, %	OR (95% CI)	P value	OR (95% CI)	P value
Total
Combination (TyG-BMI and HGI)
Low TyG-BMI and Low HGI	5.8	1 [Reference]		1 [Reference]
Low TyG-BMI and High HGI	9.3	1.36 (1.11, 1.67)	0.003	1.30 (1.04, 1.64)	0.024
High TyG-BMI and Low HGI	10	2.27 (1.72, 2.99)	< 0.001	2.40 (1.76, 3.29)	< 0.001
High TyG-BMI and High HGI	15.4	3.31 (2.41, 4.54)	< 0.001	3.47 (2.41, 4.99)	< 0.001
Normoglycemia
Combination (TyG-BMI and HGI)
Low TyG-BMI and Low HGI	5.5	1 [Reference]		1 [Reference]
Low TyG-BMI and High HGI	7.3	1.26 (0.57, 2.76)	0.572	1.68 (0.71, 3.98)	0.236
High TyG-BMI and Low HGI	2.8	0.61 (0.28, 1.32)	0.213	0.89 (0.38, 2.08)	0.79
High TyG-BMI and High HGI	4.6	0.86 (0.43, 1.72)	0.664	1.26 (0.57, 2.76)	0.565
Prediabetes
Combination (TyG-BMI and HGI)
Low TyG-BMI and Low HGI	6.2	1 [Reference]		1 [Reference]
Low TyG-BMI and High HGI	9.4	1.57 (1.12, 2.21)	0.009	1.43 (0.98, 2.10)	0.065
High TyG-BMI and Low HGI	8.4	2.15 (1.56, 2.98)	< 0.001	2.42 (1.69, 3.48)	< 0.001
High TyG-BMI and High HGI	16.7	4.45 (2.69, 7.36)	< 0.001	4.30 (2.45, 7.54)	< 0.001
Diabetes
Combination (TyG-BMI and HGI)
Low TyG-BMI and Low HGI	7.7	1 [Reference]		1 [Reference]
Low TyG-BMI and High HGI	13.2	1.96 (1.35, 2.85)	< 0.001	2.22 (1.43, 3.45)	< 0.001
High TyG-BMI and Low HGI	18.6	3.75 (2.45, 5.74)	< 0.001	4.04 (2.43, 6.73)	< 0.001
High TyG-BMI and High HGI	14.8	3.62 (2.18, 6.03)	< 0.001	4.13 (2.25, 7.59)	< 0.001

Abbreviations: HF, heart failure; TyG-BMI, triglyceride glucose-body mass index; HGI, hemoglobin glycation index; OR, odds ratio; CI, confidence interval
^a Adjusted for survey cycle, age
^b Multivariable model adjusted for survey cycle, age, sex, race, education, smoking, LDL-C, eGFR, CHD, haemoglobin, and albumin

ISSN: 1476-511X