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Table 4 Alterations of renal function indexes during the treatment in two groups

From: Effect of sacubitril/valsartan on lipid metabolism in patients with chronic kidney disease combined with chronic heart failure: a retrospective study

Indexes

Times

Sacubitril/valsartan (n = 106)

Valsartan (n = 106)

P

eGFR (ml/min)a,b

Baseline

49.62(34.76,58.65)

46.45(36.09,55.14)

0.294

16 weeks

47.55(34.5,56.91)

42.90(29.93,55.21)**

0.120

creatine (umol/L)a,b

Baseline

115.00(101.00,153.00)

123.00(106.00,159.00)

0.186

16 weeks

119.50(101.75,156.50)

129.50(106.00,177.50)***

0.074

Uric acid (mmol/L)a,b

Baseline

441.50(357.00,542.25)

444.00(338.00,530.50)

0.712

16 weeks

443.00(339.75,545.25)

439.00(361.75,518.50)

0.581

  1. eGFR estimate glomerular filtration rate
  2. a Mann-Whitney U test
  3. b Wilcoxon rank sum test
  4. Data is represented as median (quartile)
  5. **P < 0.01, ***P < 0.001 compared with before treatment