Fig. 2From: Appraising associations between signature lipidomic biomarkers and digestive system cancer risk: novel evidences from a prospective cohort study of UK Biobank and Mendelian randomization analysesPhenotypic association patterns between signature lipidomic biomarkers (HDL-C (A), LDL-C (B), and TG (C)) and the risk of DSC. Distributions of signature lipidomic biomarker concentrations and RCSs (red lines) representing shapes of phenotypic associations with adjustment of age, sex, BMI, smoking status, alcohol drinking status, education qualification, employment status, TDI, physical activity level, medication use, family cancer history, ALT, AST, SBP, DBP, primary hypertension, cerebral infarction, ischaemic heart disease, HbA1c, and diabetes. Poverall and Pnonlinear values of 0.008 (0.05/6 outcomes, Bonferroni-adjusted P) were defined as the threshold of remarkable statistical significance. Poverall and Pnonlinear values between 0.008 and 0.05 were defined as suggestive statistical significanceBack to article page