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Fig. 4 | Lipids in Health and Disease

Fig. 4

From: Appraising associations between signature lipidomic biomarkers and digestive system cancer risk: novel evidences from a prospective cohort study of UK Biobank and Mendelian randomization analyses

Fig. 4

Causal association patterns between signature lipidomic biomarkers and the risk of DSCs. Nonlinear MR analyses with piecewise linear method for genetically predicting the associations between (A) HDL-C, (B) LDL-C, and (C) TG concentrations and the risk of oesophagus, stomach, colorectal, liver, gallbladder, and pancreas cancers. Exposure and outcome regression stages were both adjusted with age, sex, assessment centers, genotyping array and the first 10 PCs. Each black dot and black vertical line represented the LACE with its 95% confidence interval in each stratum and red dots represented reference points

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Lipids in Health and Disease

ISSN: 1476-511X