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Table 1 Baseline characteristics of the study population according to the hs-CRP/HDL-C ratio

From: The predictive value of the hs-CRP/HDL-C ratio, an inflammation-lipid composite marker, for cardiovascular disease in middle-aged and elderly people: evidence from a large national cohort study

Variables

Total (n = 6554)

Q1 (n = 1639)

Q2 (n = 1638)

Q3 (n = 1638)

Q4 (n = 1639)

P

Age, years, mean (Q1, Q3)

57 (51, 63)

56 (49, 62)

57 (50, 63)

57 (51, 64)

58 (52, 65)

< 0.01

Sex, n (%)

     

< 0.01

 Female

3471 (52.96)

928 (56.62)

869 (53.05)

831 (50.73)

843 (51.43)

 

 Male

3083 (47.04)

711 (43.38)

769 (46.95)

807 (49.27)

796 (48.57)

 

Marital status, n (%)

     

0.01

 Married

5911 (90.19)

1490 (90.91)

1501 (91.64)

1471 (89.8)

1449 (88.41)

 

 Non-Married

643 (9.81)

149 (9.09)

137 (8.36)

167 (10.2)

190 (11.59)

 

Education level, n (%)

     

0.91

 Elementary school and below

4514 (68.87)

1142 (69.68)

1124 (68.62)

1112 (67.89)

1136 (69.31)

 

 High school

1365 (20.83)

337 (20.56)

348 (21.25)

347 (21.18)

333 (20.32)

 

 College and higher

675 (10.3)

160 (9.76)

166 (10.13)

179 (10.93)

170 (10.37)

 

Location of residence, n (%)

     

< 0.01

 Urban

6135 (93.61)

1571 (95.85)

1522 (92.92)

1529 (93.35)

1513 (92.31)

 

 Rural

419 (6.39)

68 (4.15)

116 (7.08)

109 (6.65)

126 (7.69)

 

Smoking status, n (%)

     

< 0.01

 Never

4051 (61.81)

1058 (64.55)

1037 (63.31)

988 (60.32)

968 (59.06)

 

 Former smoker

461 (7.03)

90 (5.49)

106 (6.47)

122 (7.45)

143 (8.72)

 

 Current smoker

2042 (31.16)

491 (29.96)

495 (30.22)

528 (32.23)

528 (32.21)

 

Drinking status, n (%)

     

0.02

 None of these

4277 (65.26)

1042 (63.58)

1030 (62.88)

1087 (66.36)

1118 (68.21)

 

 Drinks, but less than once a month

553 (8.44)

142 (8.66)

138 (8.42)

145 (8.85)

128 (7.81)

 

 Drinks more than once a month

1724 (26.3)

455 (27.76)

470 (28.69)

406 (24.79)

393 (23.98)

 

Sleep duration, hours, mean (Q1, Q3)

7 (5, 8)

7 (5, 8)

6.75 (5, 8)

7 (5, 8)

7 (5, 8)

0.86

Developed heart problems, n (%)

    

< 0.01

 No

6044 (92.22)

1529 (93.29)

1530 (93.41)

1489 (90.9)

1496 (91.28)

 

 Yes

510 (7.78)

110 (6.71)

108 (6.59)

149 (9.1)

143 (8.72)

 

Developed stroke, n (%)

    

< 0.01

 No

6230 (95.06)

1575 (96.1)

1566 (95.6)

1557 (95.05)

1532 (93.47)

 

 Yes

324 (4.94)

64 (3.9)

72 (4.4)

81 (4.95)

107 (6.53)

 

Developed CVD, n (%)

    

< 0.01

 No

5768 (88.01)

1473 (89.87)

1467 (89.56)

1422 (86.81)

1406 (85.78)

 

 Yes

786 (11.99)

166 (10.13)

171 (10.44)

216 (13.19)

233 (14.22)

 

SBP (mmHg), mean (Q1, Q3)

126 (114, 140)

122 (112, 137)

124 (113, 138)

127 (115, 141)

129 (116, 145)

< 0.01

DBP (mmHg), mean (Q1, Q3)

74 (67, 83)

73 (66, 81)

74 (67, 82)

75 (68, 83)

76 (69, 84)

< 0.01

TG (mg/dl), mean (Q1, Q3)

100 (72.57, 141.6)

83.19 (63.72, 113.28)

99.12 (72.57, 135.4)

109.74 (78.76, 153.99)

115.05 (80.54, 164.61)

< 0.01

Uric acid (mg/dl), mean (Q1, Q3)

4.24 (3.54, 5.08)

3.92 (3.32, 4.67)

4.10 (3.46, 5.00)

4.38 (3.68, 5.20)

4.56 (3.78, 5.40)

< 0.01

LDL-C (mg/dl), mean (Q1, Q3)

114.43 (94.72, 135.70)

111.73 (92.78, 132.41)

113.66 (95.10, 137.15)

118.30 (97.52, 139.18)

113.66 (92.40, 134.92)

< 0.01

Glucose (mg/dl), mean (Q1, Q3)

101.34 (93.96, 110.52)

99.72 (92.7, 107.64)

101.34 (94.14, 110.16)

101.7 (94.14, 110.52)

102.78 (95.22, 114.03)

< 0.01

HDL-C (mg/dl), mean (Q1, Q3)

50.65 (41.75, 60.7)

59.54 (51.03, 69.39)

51.42 (44.07, 60.7)

47.94 (40.21, 56.83)

44.07 (36.34, 52.58)

< 0.01

hs-CRP (mg/l), mean (Q1, Q3)

0.94 (0.51, 1.92)

0.37 (0.29, 0.46)

0.69 (0.56, 0.84)

1.28 (1.05, 1.60)

3.45 (2.41, 6.03)

< 0.01

hs-CRP/HDL-C, mean (Q1, Q3)

0.02 (0.01, 0.04)

0.01 (0.00, 0.01)

0.01 (0.01, 0.02)

0.03 (0.02, 0.03)

0.08 (0.05, 0.13)

< 0.01

  1. CVD, cardiovascular disease; HDL-C, high-density lipoprotein cholesterol; hs-CRP, high-sensitivity C-reactive protein; LDL-C, low-density lipoprotein cholesterol; Q1, the first quartile of the CRP/HDL-C ratio; Q2, the median of the CRP/HDL-C ratio; Q3, the third quartile of the CRP/HDL-C ratio; Q4, the fourth quartile of the CRP/HDL-C ratio; TG, triglyceride