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Table 2 Multivariate Cox regression analysis of the role of BMI, TyG index, TyG-BMI in assessing changes in glycemic status in patients with prediabetes

From: Relative importance of triglyceride glucose index combined with body mass index in predicting recovery from prediabetic state to normal fasting glucose: a cohort analysis based on a Chinese physical examination population

 

HR (95%CI)

E-value

Non-adjusted Model

Model I

Model II

Model III

Prediabetes to NFG

 TyG-BMI (per SD increase)

0.80 (0.79, 0.82)

0.84 (0.83, 0.86)

0.86 (0.84, 0.88)

0.90 (0.88, 0.93)

1.46

 TyG-BMI (quartiles)

   Q1

Ref

Ref

Ref

Ref

 

   Q2

0.81 (0.77, 0.85)

0.90 (0.86, 0.95)

0.92 (0.88, 0.97)

0.97 (0.92, 1.02)

 

   Q3

0.67 (0.64, 0.71)

0.78 (0.74, 0.82)

0.80 (0.76, 0.85)

0.87 (0.82, 0.93)

 

   Q4

0.59 (0.56, 0.62)

0.66 (0.63, 0.70)

0.70 (0.66, 0.74)

0.82 (0.77, 0.89)

 

 P-trend

 < 0.0001

 < 0.0001

 < 0.0001

 < 0.0001

 

Prediabetes to Diabetes

 TyG-BMI (per SD increase)

1.43 (1.39, 1.47)

1.40 (1.36, 1.45)

1.38 (1.34, 1.42)

1.26 (1.21, 1.31)

1.83

 TyG-BMI (quartiles)

   Q1

Ref

Ref

Ref

Ref

 

   Q2

1.56 (1.40, 1.74)

1.41 (1.26, 1.57)

1.38 (1.23, 1.54)

1.27 (1.12, 1.43)

 

   Q3

2.17 (1.95, 2.41)

1.90 (1.71, 2.11)

1.83 (1.64, 2.04)

1.57 (1.39, 1.76)

 

   Q4

2.81 (2.54, 3.11)

2.52 (2.27, 2.80)

2.39 (2.15, 2.66)

1.82 (1.61, 2.06)

 

P-trend

 < 0.0001

 < 0.0001

 < 0.0001

 < 0.0001

 
  1. Model I adjusted for age, sex and height
  2. Model II adjusted for age, sex, height, family history of diabetes, smoking status, drinking status, SBP, DBP
  3. Model III adjusted for age, sex, height, family history of diabetes, smoking status, drinking status, SBP, DBP, FPG, TG ALT, BUN and Cr
  4. Abbreviations: HR hazard ratios, CI confidence interval, other abbreviations as in Table 1
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Lipids in Health and Disease

ISSN: 1476-511X