Table 1 Baseline patient characteristics of individuals with ischemic stroke in the derivation cohort

Patient status

 Age, years

60.4 ± 14.4

60.3 ± 14.3

72.1 ± 14.8

< 0.001

 Sex male, n (%)

27,690 (61.31%)

27,329 (61.22%)

361 (69.16%)

< 0.001

 Smoker, n (%)

13,873 (30.72%)

13,692 (30.67%)

181 (34.67%)

0.049

 Drinker, n (%)

9046 (20.03%)

8926 (20.00%)

120 (22.99%)

0.089

 SBP, mmHg

133.5 ± 21.8

133.5 ± 21.7

126.1 ± 24.0

< 0.001

 DBP, mmHg

81.0 ± 13.0

81.1 ± 13.0

73.4 ± 15.2

< 0.001

Fat indicators

 TC, mmol/L

4.41 ± 1.09

4.41 ± 1.08

4.77 ± 1.26

< 0.001

 TG, mmol/L

1.76 ± 1.25

1.75 ± 1.24

2.11 ± 1.61

< 0.001

 HDL, mmol/L

1.12 ± 0.30

1.12 ± 0.30

1.18 ± 0.37

< 0.001

 BFP, %

30.7 ± 5.8

30.6 ± 5.8

32.5 ± 5.8

< 0.001

BMI, kg/m²

0.291

  < 18.5

580 (1.28%)

572 (1.28%)

8 (1.53%)

 18.5–24

20,579 (45.57%)

20,325 (45.53%)

254 (48.66%)

  ≥ 24

24,003 (53.15%)

23,743 (53.19%)

260 (49.81%)

Comorbidities

 Diabetes, n (%)

10,885 (24.10%)

10,705 (23.98%)

180 (34.48%)

< 0.001

 Hypertension, n (%)

24,496 (54.24%)

24,146 (54.09%)

350 (67.05%)

< 0.001

 CHD, n (%)

13,173 (29.17%)

12,827 (28.73%)

346 (66.28%)

< 0.001

 CKD, n (%)

4477 (9.91%)

4306 (9.65%)

171 (32.76%)

< 0.001

 CRD, n (%)

18,171 (40.24%)

17,754 (39.77%)

417 (79.89%)

< 0.001

Treatment

 Aspirin use, n (%)

17,130 (40.15%)

16,940 (37.95%)

190 (36.40%)

0.380

 Clopidogrel use, n (%)

13,259 (31.08%)

13,095 (29.33%)

164 (31.42%)

0.352

 Thrombolytic, n (%)

462 (1.08%)

446 (1.00%)

16 (3.07%)

< 0.001

 Insulin use, n (%)

7080 (16.59%)

6827 (15.29%)

253 (48.47%)

< 0.001

 Antihypertensive use, n (%)

17,410 (38.55%)

17,190 (38.51%)

220 (42.15%)

0.090

 Statin use, n (%)

20,278 (47.53%)

20,025 (44.86%)

253 (48.47%)

0.129

 Oxygen therapy, n (%)

12,799 (28.34%)

12,563 (28.14%)

236 (45.21%)

< 0.001