Table 2 Univariate & Multivariate analyses for the adverse outcome in the derivation cohort

Age, years

1.075 (1.066–1.082)

<0.001

1.064 (1.051–1.077)

< 0.001

Sex, Female vs Male

1.420 (1.178–1.711)

<0.001

1.097 (0.686–1.756)

0.699

Smoker, No vs Yes

1.200 (1.001–1.438)

0.049

0.831 (0.653–1.058)

0.133

Drinker, No vs Yes

1.194 (0.973–1.466)

0.090

0.893 (0.690–1.158)

0.394

SBP, mmHg

0.983 (0.979–0.987)

<0.001

0.992 (0.986–0.998)

0.011

DBP, mmHg

0.952 (0.945–0.959)

<0.001

0.988 (0.978–0.998)

0.016

BFP, %

1.052 (1.037–1.068)

<0.001

0.981 (0.942–1.021)

0.339

BMI, kg/m²

 18.5–24

Ref.

Ref.

 <18.5

1.119 (0.551–2.273)

0.756

 ≥24

0.876 (0.736–1.043)

0.137

TC, mmol/L

1.322 (1.230–1.421)

<0.001

1.139 (1.039–1.248)

0.005

TG, mmol/L

1.180 (1.123–1.241)

<0.001

1.110 (1.041–1.183)

0.001

HDL, mmol/L

1.935 (1.482–2.527)

<0.001

1.345 (0.978–1.850)

0.068

Diabetes, n (%)

1.668 (1.391–2.001)

<0.001

0.684 (0.551–0.851)

0.001

Hypertension, n (%)

1.727 (1.438–2.075)

<0.001

0.974 (0.783–1.211)

0.813

CHD, n (%)

4.876 (4.062–5.852)

<0.001

1.914 (1.555–2.356)

<0.001

CKD, n (%)

4.563 (3.791–5.493)

<0.001

1.532 (1.236–1.899)

<0.001

CRD, n (%)

6.014 (4.851–7.455)

<0.001

2.712 (2.140–3.438)

<0.001

Aspirin use, No vs Yes

0.922 (0.768–1.106)

0.380

Clopidogrel, No vs Yes

1.093 (0.906–1.320)

0.352

Thrombolytic, No vs Yes

3.112 (1.875–5.165)

<0.001

1.091 (0.636–1.872)

0.753

Insulin use, No vs Yes

5.368 (4.494–6.412)

<0.001

3.338 (2.709–4.113)

<0.001

Statin use, No vs Yes

1.147 (0.961–1.368)

0.130

Antihypertensive use, No vs Yes

1.163 (0.977–1.385)

0.090

Oxygen therapy, No vs Yes

2.107 (1.771–2.506)

<0.001

1.156 (0.956–1.399)

0.136