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Table 2 Univariate and multivariate modified Poisson regression models for association between biomarkers of inflammation and dyslipidemia

From: Association between biomarkers of inflammation and dyslipidemia in drug resistant tuberculosis in Uganda

Characteristic

cPR

95% CI

p-value

aPR

95% CI

P-value

 

Bivariable Analysis

Multivariable Analysis

Modified poisson regression for associations with dyslipidemia

Lymphocyte count

1.15

0.93, 1.41

0.189

1.00

0.64, 1.57

0.990

Monocyte count

2.07

1.15, 3.73

0.015

1.08

0.24, 4.75

0.920

Platelet count

1.00

1.00, 1.00

0.189

1.00

0.99, 1.00

0.996

Red cell distribution width

0.98

0.94, 1.02

0.237

1.00

0.95, 1.06

0.871

Mean corpuscular volume

0.98

0.97, 0.99

0.015

0.98

0.96, 1.01

0.132

Lymphocyte Monocyte Ratio

0.98

0.95, 1.00

0.094

0.98

0.96, 1.01

0.295

Neutrophil Lymphocyte Ratio

1.00

0.99, 1.00

0.711

1.00

0.99, 1.00

0.893

Hyperglycemia (HbA1c > 5.6%)

1.36

0.75, 2.49

0.310

0.99

0.42, 2.31

0.973

High body mass index (≥ 25.0 kg/m2)

0.69

0.32, 1.49

0.345

0.46

0.11, 1.94

0.288

HIV infection

1.08

0.76, 1.55

0.663

1.30

0.80, 2.12

0.292

Any history of smoking tobacco

0.96

0.66, 1.40

0.883

1.07

0.65, 1.77

0.791

Central obesity

0.86

0.59, 1.24

0.411

0.80

0.50, 1.28

0.347

Modified poisson regression for associations with low hdl-c

Lymphocyte count

0.88

0.66, 1,18

0.402

0.98

0.57, 1.68

0.936

Monocyte count

0.90

0.38, 2.10

0.801

1.29

0.22, 7.68

0.780

Platelet count

1.00

0.99, 1.00

0.334

1.00

0.99, 1.00

0.191

Red cell distribution width

1.05

1.01, 1.10

0.017

1.04

0.98, 1.10

0.211

Mean corpuscular volume

0.99

0.97, 1.01

0.206

0.97

0.94, 0.99

0.023

Lymphocyte Monocyte Ratio

0.99

0.97, 1.01

0.443

0.99

0.96, 1.02

0.487

Neutrophil Lymphocyte Ratio

1.00

0.99, 1.00

0.981

1.00

0.99, 1.00

0.510

Hyperglycemia (HbA1c > 5.6%)

1.26

0.54, 2.93

0.595

1.11

0.40, 3.07

0.846

High body mass index (≥ 25.0 kg/m2)

0.34

0.08, 1.39

0.134

0.65

0.15, 2.76

0.557

HIV infection

1.57

0.98, 2.52

0.063

1.73

0.96, 3.11

0.067

Any history of smoking tobacco

0.70

0.41, 1.19

0.191

0.71

0.37, 1.36

0.307

Central obesity

0.84

0.51, 1.37

0.486

0.78

0.44, 1.37

0.382

Modified poisson regression model for associations with elevated tryglicerides

Lymphocyte count

0.88

0.59, 1.29

0.503

1.51

0.70, 3.27

0.293

Monocyte count

1.23

0.41, 3.71

0.705

0.88

0.07, 10.67

0.922

Platelet count

1.00

0.99, 1.00

0.596

1.00

0.99, 1.01

0.469

Red cell distribution width

1.01

0.94, 1.07

0.861

1.00

0.92, 1.09

0.966

Mean corpuscular volume

1.01

0.99, 1.03

0.438

1.04

1.00. 1.08

0.052

Lymphocyte Monocyte Ratio

0.97

0.92, 1.02

0.278

0.95

0.87, 1.03

0.231

Neutrophil Lymphocyte Ratio

1.00

1.00, 1.00

0.141

1.00

0.99, 1.00

0.286

Hyperglycemia (HbA1c > 5.6%)

1.72

0.67, 4.44

0.258

1.76

0.45, 6.86

0.418

High body mass index (≥ 25.0 kg/m2)

2.16

0.90, 5.20

0.086

1.63

0.33, 7.95

0.546

HIV infection

0.93

0.49, 1.78

0.835

0.87

0.39, 1.98

0.752

Any history of smoking tobacco

0.74

0.37, 1.49

0.400

0.73

0.30, 1.80

0.496

Central obesity

1.20

0.63, 2.28

0.572

0.78

0.35, 1.73

0.542

  1. Systemic inflammatory index = neutrophil × platelet/lymphocyte; central obesity was defined as waist circumference of ≥ 102/88 cm and/or a waist-hip ratio of ≥ 0.90/0.85 in males/females; HDL-c – High density lipoprotein cholesterol, cPR – crude prevalence ratio, aPR – adjusted prevalence ratio, CI – confidence interval. Bolded p-values indicate statistically significant results
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Lipids in Health and Disease

ISSN: 1476-511X