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Table 1 Serum measurements of Epas1-bKO mice after 8 weeks of HFD feeding

From: PDGFRβ + cell HIF2α is dispensable for white adipose tissue metabolic remodeling and hepatic lipid accumulation in obese mice

 

Control + Chow

Epas1-bKO + Chow

Control + HFD

Epas1-bKO + HFD

Serum TG (mg/dL)

47.73 ± 3.7

44.56 ± 3.3

93.14 ± 5.1*

96.81 ± 4.6#

Serum Adiponectin (μg/mL)

9.16 ± 0.5

9.89 ± 0.9

5.98 ± 0.2

5.9 ± 0.4

Serum TNF-α (pg/mL)

18.42 ± 2.1

20.83 ± 3.2

38.84 ± 3.5*

40.49 ± 4.4

Fasting glucose (mg/dL)

96.83 ± 7.2

100.5 ± 7.3

145.17 ± 7.9*

139.33 ± 13.1#

Fasting insulin (ng/mL)

0.53 ± 0.1

0.51 ± 0.1

0.9 ± 0.1

0.93 ± 0.1

  1. Values are mean ± SEM (n = 6 per group). *P < 0.05 control mice compared with HFD mice by two-way ANOVA. #P < 0.05 Epas1-bKO mice fed with chow diet compared with Epas1-bKO mice fed with HFD by two-way ANOVA