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Table 2 Association between TyG index and GDM

From: Triglyceride-glucose index in early pregnancy predicts the risk of gestational diabetes: a prospective cohort study

Predictor

Number

GDM, n (%)

Crude

Model 1a

Model 2b

OR (95% CI)

P value

OR (95% CI)

P value

OR (95% CI)

P value

TyG index, per unit

1624

447 (27.5)

2.30 (1.89–2.78)

< 0.001

2.10 (1.72–2.56)

< 0.001

2.81 (2.10–3.77)

< 0.001

TyG index, per SD

1624

447 (27.5)

1.67 (1.48–1.87)

< 0.001

1.58 (1.40–1.78)

< 0.001

1.89 (1.58–2.26)

< 0.001

TyG index Quintile 1

325

53 (16.3)

1 (Ref)

 

1 (Ref)

 

1 (Ref)

 

Quintile 2

325

68 (20.9)

1.36 (0.91–2.02)

0.131

1.30 (0.87–1.94)

0.206

1.44 (0.93–2.23)

0.105

Quintile 3

325

80 (24.6)

1.68 (1.14–2.47)

0.009

1.54 (1.03–2.29)

0.034

1.67 (1.07–2.61)

0.025

Quintile 4

325

108 (33.2)

2.55 (1.76–3.71)

< 0.001

2.32 (1.58–3.40)

< 0.001

2.82 (1.80–4.42)

< 0.001

Quintile 5

324

138 (42.6)

3.81 (2.64–5.50)

< 0.001

3.25 (2.23–4.75)

< 0.001

3.87 (2.34–6.38)

< 0.001

Trend test

   

< 0.001

 

< 0.001

 

< 0.001

  1. aModel 1 adjusted for ethnic, pre-pregnancy BMI, maternal age, assisted reproduction, abortion history, gravidity, parity, delivery gestations, and GWG
  2. bModel 2 further adjusted for gestational week at the examination, SBP, DBP, TC, LDL-C, HDL-C, Hb, UA, Cr, ALT and AST