Fig. 2From: Significant but partial lipoprotein lipase functional loss caused by a novel occurrence of rare LPL biallelic variantsIn silico analyses pertaining to the LPL p.Val111Leu and p.Arg270His variants. (a) Alignment of partial vertebrate LPL amino acid sequences spanning the p.Val111 site. (b) Conservation and pathogenicity scores of the LPL p.Val111 site as predicted by the indicated programs. (c) Alignment of partial vertebrate LPL amino acid sequences spanning the p.Arg270 site. (d) Conservation and pathogenicity scores of the LPL p.Arg270 site as predicted by the indicated programs. (e) Predicted partial 3D structures of the wild-type and variant LPL proteinsBack to article page