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Fig. 3 | Lipids in Health and Disease

Fig. 3

From: Lipid droplet accumulation in Wdr45-deficient cells caused by impairment of chaperone-mediated autophagic degradation of Fasn

Fig. 3

Fasn promotes LD accumulation in Wdr45 knockout cells. (A) LD density of WT and KO cells treated with or without 300 μM OA for 24 h. (B) The protein expression level of Fasn (n = 4 independent experiments). (C) LD density of WT and KO cells treated with 20 μM Fasn inhibitor C75 or 20 μM CMA activator AR7 for 24 h. The data are expressed as the mean ± SD; *p < 0.05, ** p < 0.01, *** p < 0.001

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Lipids in Health and Disease

ISSN: 1476-511X