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Table 2 Association of NHHR with kidney stone and a recurrence of passing kidney stones

From: The association between non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR) and kidney stones: a cross-sectional study

Exposure

Model 1

Model 2

Model 3

 

OR(95%CI), P-value

OR(95%CI), P-value

OR(95%CI), P-value

Nephrolithiasis

   

NHHR

1.08 (1.05, 1.12) < 0.0001

1.07 (1.04, 1.11) < 0.0001

1.04 (1.00, 1.08) 0.0373

Categories

   

Q1

1.0

1.0

1.0

Q2

1.27 (1.10, 1.46) 0.0012

1.22 (1.05, 1.41) 0.0074

1.15 (0.97, 1.37) 0.1132

Q3

1.47 (1.28, 1.69) < 0.0001

1.40 (1.22, 1.62) < 0.0001

1.25 (1.05, 1.49) 0.0104

Q4

1.55 (1.35, 1.78) < 0.0001

1.47 (1.27, 1.69) < 0.0001

1.28 (1.07, 1.52) 0.0058

P for trend

1.14 (1.10, 1.19) < 0.0001

1.13 (1.08, 1.18) < 0.0001

1.08 (1.02, 1.14) 0.0086

Nephrolithiasis recurrence

   

NHHR

1.14 (1.10, 1.19) < 0.01

1.12 (1.07, 1.17) < 0.01

1.09 (1.03, 1.14) < 0.01

Categories

   

Q1

1.0

1.0

1.0

Q2

1.54 (1.19, 1.98) 0.0009

1.46 (1.13, 1.89) 0.0037

1.26 (0.93, 1.70) 0.1380

Q3

1.77 (1.38, 2.27) < 0.0001

1.63 (1.27, 2.09) 0.0001

1.34 (1.00, 1.81) 0.0527

Q4

2.13 (1.68, 2.71) < 0.0001

1.90 (1.49, 2.44) < 0.0001

1.58 (1.18, 2.12) 0.0024

P for trend

1.24 (1.16, 1.33) < 0.0001

1.20 (1.12, 1.29) < 0.0001

1.15 (1.05, 1.25) 0.0026

  1. In the analysis, NHHR was transformed from a continuous variable into a categorical variable using quartiles
  2. OR, odds ratio; 95% CI, 95% confidence interval
  3. Model 1 did not incorporate any variable adjustments
  4. Model 2 adjusted for sex, age, and race
  5. Model 3 extended these adjustments to include a more comprehensive set of variables: sex, age, race, educational level, marital status, Poverty Income Ratio (PIR), Body Mass Index (BMI), vigorous activity, moderate activity, hypertension, diabetes, alcohol and smoking habits