Study of association of leptin with leukocyte telomere length in a Chinese rural population

Table 4 The interaction between ΔLEP and ΔHOMA-IR, ΔHOMA-β, ΔQUICKI influences ΔRLTL (n = 1624)

Variables	Model 1		Model 2		Model 3		Model 4
Variables	F	P-value	F	P-value	F	P-value	F	P-value
ΔLEP	7.916	0.005	5.934	0.015	6.116	0.014	6.394	0.012
ΔHOMA-IR	0.525	0.469	0.807	0.370	0.857	0.355	0.826	0.364
ΔHOMA-β	0.998	0.318	0.696	0.405	0.668	0.414	0.352	0.553
ΔQUICKI	0.214	0.644	0.094	0.759	0.121	0.728	0.054	0.817
ΔLEP * ΔHOMA-IR	0.257	0.612	0.185	0.668	0.154	0.695	0.144	0.704
ΔLEP * ΔHOMA-β	1.790	0.182	1.809	0.179	1.841	0.176	1.677	0.196
ΔLEP * ΔQUICKI	0.001	0.995	0.017	0.896	0.036	0.850	0.053	0.817

Abbreviations: ΔLEP: absolute change of leptin; ΔHOMA-IR: absolute change of Homeostatic Model Assessment for Insulin Resistance; ΔHOMA-β: absolute change of Homeostatic Model Assessment for β-Cell Function; ΔQUICKI: absolute change of Quantitative insulin sensitivity check index. Model 1: no adjusted; Model 2: Model 1 + sex, age; Model 3: Model 2 + education, smoking, drinking, physical exercise; Model 4: Model 3 + BMI, SBP, DBP, FPG.

ISSN: 1476-511X