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Table 5 Comparison of spontaneous abortion rates among pregnant women at different gestational weeks and TPOAb levels

From: Evaluation of the therapeutic efficacy of different doses of LT4 in pregnant women with high-normal TSH levels and TPOAb positivity in the first half of pregnancy

Parameter

TPOAb (IU/mL)

G0 (n = 122) (%)

G25 (n = 69) (%)

G50 (n = 58) (%)

P

Gestational weeks < 11.22

-

30.0(18/60)

20(9/45)

3.7(1/27)

0.021

< 117

17.9(5/28)

18.8(3/16)

0(0/9)

0.526

≥ 117

40.6(13/32)

20.7(6/29)

5.6(1/18) f

0.018

Gestational weeks ≥ 11.22

-

4.8(3/62)

0(0/24)

3.2(1/31)

0.810

< 117

6.7(2/30)

0(0/5)

6.7(1/15)

1.0

≥ 117

3.1(1/32)

0(0/19)

0(0/16)

1.0

  1. f indicates P = 0.008 compared to the G0 group. All comparisons were corrected with Bonferroni correction