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Table 1 Clinical characteristics of patients according to the level of NAR

From: The neutrophil-to-apolipoprotein A1 ratio is associated with adverse outcomes in patients with acute decompensated heart failure at different glucose metabolic states: a retrospective cohort study

 

Total(n = 1233)

NAR-L(NAR<4.44)

(n = 633)

NRA-H(NAR ≥ 4.44)

(n = 600)

P value

Female, n (%)

540 (43.8)

311 (49.1)

229 (38.2)

< 0.001

Age (years)

73.00 [64.00, 80.00]

74.00 [65.00, 80.00]

73.00 [62.00, 81.00]

0.145

BMI (kg/m2)

23.74 [21.88, 25.56]

23.71 [21.88, 25.39]

23.79 [21.88, 25.88]

0.35

Smoking, n (%)

270 (21.9)

130 (20.5)

140 (23.3)

0.264

Drinking, n (%)

139 (11.3)

73 (11.5)

66 (11.0)

0.837

Glucose metabolism status, n (%)

DM

610 (49.5)

288 (45.5)

322 (53.7)

0.005

Pre-DM

445 (36.1)

238 (37.6)

207 (34.5)

0.283

NGR

178 (14.4)

107 (16.9)

71 (11.8)

0.014

Medical history, n (%)

Hypertension

816 (66.2)

397 (62.7)

419 (69.8)

0.01

Hyperuricemia

535 (43.4)

237 (37.4)

298 (49.7)

< 0.001

Infection

280 (22.7)

90 (14.2)

190 (31.7)

< 0.001

PCI

259 (21.0)

109 (17.2)

150 (25.0)

0.001

Prior MI

171 (13.9)

67 (10.6)

104 (17.3)

0.001

Prior stroke

280 (22.7)

132 (20.9)

148 (24.7)

0.126

Valvular heart disease

197 (16.0)

98 (15.5)

99 (16.5)

0.682

Atrial fibrillation

608 (49.3)

307 (48.5)

301 (50.2)

0.597

Anemia

281 (22.8)

149 (23.5)

132 (22.0)

0.565

Medications at admission, n (%)

CCBs

258 (20.9)

135 (21.3)

123 (20.5)

0.774

ACEIs/ARBs

510 (41.4)

289 (45.7)

221 (36.8)

0.002

Beta blockers

818 (66.3)

406 (64.1)

412 (68.7)

0.105

Diuretics

946 (76.7)

463 (73.1)

483 (80.5)

0.003

Digitalis

237 (19.2)

113 (17.9)

124 (20.7)

0.237

Antiplatelets

594 (48.2)

290 (45.8)

304 (50.7)

0.099

Anticoagulants

346 (28.1)

173 (27.3)

173 (28.8)

0.6

Statins

670 (54.3)

324 (51.2)

346 (57.7)

0.026

LVEF (%)

45.00 [35.00, 54.00]

46.00 [37.00, 54.25]

43.00 [33.00, 52.00]

< 0.001

LVDs (cm)

4.34 [3.70, 5.15]

4.26 [3.67, 4.98]

4.41 [3.73, 5.35]

0.005

LVDd (cm)

5.70 [5.16, 6.40]

5.70 [5.15, 6.27]

5.72 [5.20, 6.50]

0.047

PAP (mmHg)

42.00 [35.00, 50.00]

40.00 [35.00, 50.00]

42.00 [35.00, 50.00]

0.272

NAR (×109/mmol)

4.37 [3.16, 6.07]

3.20 [2.50, 3.86]

6.16 [5.16, 8.30]

< 0.001

Neutrophil counts (×109/L)

4.01 [3.10, 5.23]

3.19 [2.56, 3.80]

5.14 [4.31, 6.59]

< 0.001

ApoA1 (mmol/L)

0.92 [0.77, 1.09]

1.03 [0.89, 1.17]

0.80 [0.69, 0.94]

< 0.001

ApoB (mmol/L)

0.72 [0.56, 0.89]

0.71 [0.55, 0.88]

0.72 [0.58, 0.90]

0.441

HbA1c (%)

6.18 [5.80, 6.80]

6.10 [5.79, 6.68]

6.22 [5.80, 7.00]

0.001

FPG (mmol/L)

5.12 [4.56, 6.18]

5.01 [4.52, 5.77]

5.29 [4.63, 6.69]

< 0.001

BNP (ng/L)

538.00 [235.00, 934.00]

442.00 [201.00, 777.30]

644.00 [318.25, 1242.50]

< 0.001

WBC (×109/L)

6.20 [5.00, 7.70]

5.20 [4.40, 6.10]

7.60 [6.30, 8.90]

< 0.001

RBC (×1012/L)

4.25 [3.76, 4.64]

4.24 [3.76, 4.57]

4.25 [3.76, 4.75]

0.065

PLT (×109/L)

167.00 [132.00, 207.00]

157.00 [123.00, 193.00]

179.50 [140.75, 223.00]

< 0.001

HB (g/L)

128.00 [112.00, 141.00]

128.00 [113.00, 140.00]

128.50 [111.00, 142.00]

0.418

ALT (U/L)

19.40 [13.60, 31.00]

18.90 [13.70, 27.80]

20.80 [13.57, 34.40]

0.012

AST (U/L)

23.30 [18.10, 31.70]

23.30 [18.60, 30.40]

23.25 [17.40, 34.00]

0.771

Total cholesterol (mmol/L)

3.63 [3.01, 4.42]

3.81 [3.20, 4.60]

3.44 [2.90, 4.19]

< 0.001

Triglyceride (mmol/L)

1.04 [0.76, 1.44]

1.03 [0.73, 1.46]

1.04 [0.79, 1.43]

0.202

LDL-C (mmol/L)

1.94 [1.48, 2.52]

2.00 [1.51, 2.59]

1.89 [1.44, 2.44]

0.028

HDL-C (mmol/L)

0.96 [0.77, 1.20]

1.10 [0.89, 1.33]

0.85 [0.70, 1.01]

< 0.001

ALB (g/L)

38.20 [35.60, 40.80]

38.80 [36.50, 41.40]

37.20 [34.68, 39.82]

< 0.001

CRP (mg/L)

4.20 [2.40, 9.70]

3.50 [2.10, 5.50]

6.10 [2.90, 20.97]

< 0.001

UA (µmol/L)

428.00 [337.00, 547.00]

406.00 [325.00, 506.00]

454.00 [357.00, 584.00]

< 0.001

Scr (µmol/L)

84.00 [67.00, 110.00]

78.00 [63.00, 99.00]

93.50 [73.00, 121.25]

< 0.001

eGFR (ml/min)

69.00 [47.60, 87.00]

74.00 [54.00, 89.30]

62.00 [42.75, 81.00]

< 0.001

Serum potassium (mmol/L)

3.95 [3.68, 4.25]

3.96 [3.69, 4.20]

3.94 [3.66, 4.30]

0.701

Serum sodium (mmol/L)

141.00 [138.00, 142.90]

141.30 [138.90, 143.20]

140.45 [137.20, 142.60]

< 0.001