Table 1 Weighted characteristics of the eligible 27,301 participants in the analysis of PHR and HDL-C with the odds of stroke

PHR, median(Q1,Q3)

183.19(141.38,236.73)

183.33(141.52,236.73)

178.83(136.65,238.55)

0.35

Platelet (1000 cells/μL), median(Q1,Q3)

241.00(206.00,285.00)

242.00(206.00,285.00)

233.00(192.00,278.00)

0.002

HDL-C (mmol/L), median(Q1,Q3)

1.32(1.09,1.60)

1.32(1.09,1.60)

1.29(1.03,1.60)

0.02

Age (year), Mean (S.E)

47.28(0.25)

46.79(0.25)

64.13(0.59)

 < 0.0001

Sex, n (%)

0.02

 Female

13,619(50.57)

13,094(50.42)

525(55.52)

 Male

13,682(49.43)

13,167(49.58)

515(44.48)

Race, n (%)

 < 0.0001

 Mexican American

4160(7.94)

4066(8.04)

94(4.35)

 Non-Hispanic Black

5585(10.15)

5318(10.06)

267(13.44)

 Non-Hispanic White

12,415(70.22)

11,858(70.15)

557(72.86)

 Other Hispanic

2467(5.00)

2402(5.06)

65(2.95)

 Other Race—Including Multi-Racial

2674(6.68)

2617(6.69)

57(6.40)

Education attainment, n (%)

 < 0.0001

 Less than college

12,508(37.69)

11,893(37.22)

615(53.84)

 College or higher

14,793(62.31)

14,368(62.78)

425(46.16)

Marital status, n (%)

 < 0.0001

 Never married

4861(17.54)

4780(17.86)

81(6.55)

 Divorced/separated/widowed

6015(18.21)

5615(17.78)

400(32.79)

 Married/living with a partner

16,425(64.25)

15,866(64.36)

559(60.67)

Poverty, n (%)

 < 0.0001

  < 1.3

8256(20.06)

7845(19.74)

411(31.02)

 1.3–3.5

10,339(35.54)

9893(35.26)

446(45.14)

  > 3.5

8706(44.40)

8523(45.00)

183(23.84)

Alcohol status, n (%)

 < 0.0001

 Never

3647(10.28)

3483(10.16)

164(14.25)

 Former

4455(13.23)

4101(12.72)

354(30.66)

 Now

19,199(76.49)

18,677(77.12)

522(55.09)

Smoke, n (%)

 < 0.0001

 Never

14,872(54.90)

14,463(55.28)

409(41.54)

 Former

6747(25.03)

6355(24.72)

392(35.88)

 Now

5682(20.07)

5443(20.00)

239(22.58)

Body Mass Index (BMI), Mean (S.E)

29.08(0.08)

29.04(0.08)

30.37(0.29)

 < 0.0001

Total energy intake (Kcal) Mean (S.E)

2195.67(8.93)

2205.53(8.68)

1856.94(41.05)

 < 0.0001

Cancer, n (%)

2581(9.92)

2355(9.59)

226(21.29)

 < 0.0001

Thyroid problem, n (%)

2811(10.93)

2602(10.58)

209(22.70)

 < 0.0001

Liver diseases, n (%)

1057(3.47)

982(3.37)

75(6.90)

 < 0.0001

Arthritis, n (%)

7472(25.76)

6877(24.87)

595(56.24)

 < 0.0001

Diabetes, n (%)

 < 0.0001

 DM

5051(13.83)

4623(13.15)

428(36.95)

 IFG

1278(4.82)

1230(4.79)

48(5.86)

 IGT

1099(3.62)

1059(3.63)

40(3.12)

 No

19,873(77.74)

19,349(78.43)

524(54.06)

Depression, n (%)

2336(7.47)

2151(7.18)

185(17.18)

 < 0.0001

Coronary heart disease, n (%)

1099(3.36)

922(2.94)

177(18.05)

 < 0.0001

CKD, n (%)

4788(13.90)

4315(13.11)

473(41.01)

 < 0.0001

Hypertension, n (%)

11,593(37.60)

10,747(36.42)

846(78.39)

 < 0.0001

Antiplatelets, n (%)

948(2.46)

693(1.87)

255(22.72)

 < 0.0001

Statin drugs, n (%)

5147(16.75)

4618(15.74)

529(51.37)

 < 0.0001