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Table 2 Weighted multivariate Logistic regression analysis for the association of stroke with PHR and HDL-C

From: The association of the platelet/high-density lipoprotein cholesterol ratio with self-reported stroke and cardiovascular mortality: a population-based observational study

PHR

 

Model 0

Model 1

Model 2

Model 3

Overall

 

OR (95% CI)

P

OR (95% CI)

P

OR (95% CI)

P

OR (95% CI)

P

Per SD increase

1.03(0.93,1.15)

0.55

1.23(1.13,1.33)

 < 0.0001

1.17(1.07,1.27)

 < 0.001

1.13(1.03,1.24)

0.01

Per 100 increase

1.04(0.91,1.19)

0.55

1.29(1.16,1.42)

 < 0.0001

1.21(1.09,1.34)

 < 0.001

1.16(1.04,1.30)

0.01

PHR < 223.684

Per SD increase

0.87(0.78,0.97)

0.01

1.02(0.92,1.14)

0.65

0.98(0.89,1.09)

0.77

0.97(0.87,1.08)

0.53

Per 100 increase

0.70(0.54,0.91)

0.01

1.06(0.81,1.39)

0.65

0.96(0.74,1.26)

0.77

0.92(0.70,1.20)

0.53

PHR ≥ 223.684

Per SD increase

1.22(1.12,1.33)

 < 0.0001

1.26(1.14,1.38)

 < 0.0001

1.22(1.12,1.34)

 < 0.0001

1.20(1.09,1.31)

 < 0.001

Per 100 increase

1.31(1.17,1.47)

 < 0.0001

1.36(1.19,1.55)

 < 0.0001

1.32(1.16,1.49)

 < 0.0001

1.27(1.13,1.44)

 < 0.001

HDL-C

 

Model 0

Model 1

Model 2

Model 3

Overall

 

OR (95% CI)

P

OR (95% CI)

P

OR (95% CI)

P

OR (95% CI)

P

Per SD increase

0.92(0.83,1.01)

0.08

0.79(0.71,0.88)

 < 0.0001

0.90(0.81,1.01)

0.07

0.95(0.86,1.05)

0.30

Per 1 increase

0.81(0.65,1.02)

0.08

0.56(0.44,0.73)

 < 0.0001

0.78(0.59,1.02)

0.07

0.88(0.70,1.12)

0.30

HDL-C ≥ 1.4 mmol/L

Per SD increase

0.87(0.77,0.97)

0.01

0.79(0.70,0.90)

 < 0.001

0.86(0.75,0.97)

0.02

0.91(0.80,1.03)

0.14

Per 1 increase

0.46(0.25,0.83)

0.01

0.29(0.15,0.55)

 < 0.001

0.43(0.22,0.87)

0.02

0.60(0.30,1.20)

0.14

HDL-C ≥ 1.4 mmol/L

Per SD increase

1.09(0.97,1.22)

0.14

1.00(0.88,1.14)

0.99

1.06(0.94,1.21)

0.35

1.04(0.92,1.19)

0.53

Per 1 increase

1.28(0.92,1.79)

0.14

1.00(0.68,1.46)

0.99

1.20(0.82,1.74)

0.35

1.13(0.77,1.66)

0.53

  1. Model 0: Not adjusted
  2. Model 1: Adjusted for age, sex, education attainment, and ethnicity
  3. Model 2: Further adjusted for marital status, poverty-income ratio, smoking, and drinking status, BMI, and total energy intake based on Model 1
  4. Model 3: Further adjusted for arthritis, thyroid problems, cancer, diabetes, depression, hypertension, liver diseases, CHD, and CKD on Model 2
  5. Abbreviations: HDL-C High-density lipoprotein cholesterol, PHR Platelet-to-high-density lipoprotein cholesterol ratio, BMI Body mass index, CHD Coronary heart disease, CKD Chronic kidney disease, SD Standard deviation, OR Odds ratio, CI Confidence interval