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  1. Tree shrew and beijing duck are regarded as animal models resistant to atherosclerosis (AS). This study was carried out to discover the potential mechanism.

    Authors: Hui-rong Liu, Gang Wu, Bing Zhou and Bao-sheng Chen
    Citation: Lipids in Health and Disease 2010 9:114
    Content type: Research Published on:

  3. Nutritional factors play a major role in cancer initiation and development. Dietary polyunsaturated fatty acids (PUFAs) have the ability to induce modifications in the activity of lipoxygenase (LOX) and cycloo...

    Authors: Andrea Comba, Damian M Maestri, María A Berra, Carolina Paola Garcia, Undurti N Das, Aldo R Eynard and María E Pasqualini
    Citation: Lipids in Health and Disease 2010 9:112
    Content type: Research Published on:

  4. The enzyme 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) amplifies intracellular glucocorticoid action by converting inactive glucocorticoids to their active forms in vivo. Adipose-specific overexpression of...

    Authors: Sakamuri SS Vara Prasad, Shanmugam S Jeya Kumar, Putcha Uday Kumar, Syed SYH Qadri and Ayyalasomayajula Vajreswari
    Citation: Lipids in Health and Disease 2010 9:111
    Content type: Short paper Published on:

  5. Endothelial lipase (EL) is a major determinant of high-density lipoprotein-cholesterol (HDL-C) metabolism, but the association of endothelial lipase gene (LIPG) polymorphism and serum HDL-C levels is scarce and c...

    Authors: Wan-Ying Liu, Rui-Xing Yin, Lin Zhang, Xiao-Li Cao, Lin Miao, Dong-Feng Wu, Lynn Htet Htet Aung, Xi-Jiang Hu, Wei-Xiong Lin and De-Zhai Yang
    Citation: Lipids in Health and Disease 2010 9:110
    Content type: Research Published on:

  6. Cytokines (IL-6, IL-10 and TNF-α) are increased after exhaustive exercise in the rat retroperitoneal (RPAT) and mesenteric adipose tissue (MEAT) pads. On the other hand, these cytokines show decreased expressi...

    Authors: Fábio S Lira, José C Rosa, Gustavo D Pimentel, Victor AF Tarini, Ricardo M Arida, Flávio Faloppa, Eduardo S Alves, Cláudia O do Nascimento, Lila M Oyama, Marília Seelaender, Marco T de Mello and Ronaldo VT Santos
    Citation: Lipids in Health and Disease 2010 9:109
    Content type: Research Published on:

  9. Some polyunsaturated fatty acids (PUFAs), if not all, have been shown to have tumoricidal action, but their exact mechanism(s) of action is not clear. In the present study, we observed that n-6 PUFA linoleic a...

    Authors: Xiaofeng Lu, Haining Yu, Qi Ma, Shengrong Shen and Undurti N Das
    Citation: Lipids in Health and Disease 2010 9:106
    Content type: Research Published on:

  10. Polyunsaturated fatty acids are essential nutrients for humans. They are structural and functional components of cell membranes and pre-stages of the hormonally and immunologically active eicosanoids. Recent d...

    Authors: Michael Huss, Andreas Völp and Manuela Stauss-Grabo
    Citation: Lipids in Health and Disease 2010 9:105
    Content type: Research Published on:

  12. Oxidized lipoproteins play important roles in the atherosclerotic processes. Oxidized lipoprotein(a) (oxLp(a)) may be more potent in atherosclerotic pathophysiology than native Lp(a), a cardiovascular disease-...

    Authors: Kazuhiko Kotani, Shingo Yamada, Shuumarjav Uurtuya, Toshiyuki Yamada, Nobuyuki Taniguchi and Ikunosuke Sakurabayashi
    Citation: Lipids in Health and Disease 2010 9:103
    Content type: Short paper Published on:

  13. It has been well documented that apolipoprotein M (apoM) is principally expressed in the liver and kidney. However we found that there was weak apoM expression in other tissues or organs too, which could not b...

    Authors: Guanghua Luo, Xiaoying Zhang, Qinfeng Mu, Lujun Chen, Lu Zheng, Jiang Wei, Maria Berggren-Söderlund, Peter Nilsson-Ehle and Ning Xu
    Citation: Lipids in Health and Disease 2010 9:102
    Content type: Research Published on:

  14. Fish oil is known to improve lifestyle-related diseases. These effects occur partly via activation of PPARs by the n-3 polyunsaturated fatty acids included abundantly in fish oil. We investigated fish oil func...

    Authors: Masaki Wakutsu, Nobuyo Tsunoda, Sachiko Shiba, Etsuko Muraki and Keizo Kasono
    Citation: Lipids in Health and Disease 2010 9:101
    Content type: Research Published on:

  15. The body mass index (BMI) is the most commonly used marker for evaluating obesity related risks, however, central obesity measures have been proposed to be more informative. Lipid accumulation product (LAP) is...

    Authors: Mohammadreza Bozorgmanesh, Farzad Hadaegh and Fereidoun Azizi
    Citation: Lipids in Health and Disease 2010 9:100
    Content type: Research Published on:

  16. The Berlin Fat Mouse Inbred (BFMI) line is a new mouse model for obesity, which was long-term selected for high fatness. Peroxisome proliferator-activated receptors (PPARs) are involved in the control of energ...

    Authors: Asja Wagener, Helge F Goessling, Armin O Schmitt, Susanne Mauel, Achim D Gruber, Richard Reinhardt and Gudrun A Brockmann
    Citation: Lipids in Health and Disease 2010 9:99
    Content type: Research Published on:

  17. Docosahexaenoic acid (DHA, 22:6ω3) is a fundamental component of cell membranes, especially in the brain and retina. In the experimental animal, DHA deficiency leads to suboptimal neurological performance and ...

    Authors: Manuela Martinez, Natalia Ichaso, Fernando Setien, Nuria Durany, Xiao Qiu and William Roesler
    Citation: Lipids in Health and Disease 2010 9:98
    Content type: Research Published on:

  19. Low level of high density lipoprotein cholesterol (HDL-C) has high prevalence in the Tehran Lipid and Glucose Study (TLGS) cohort. About 50% of the inter-individual variation in serum HDL-C levels is genetical...

    Authors: Mohammad Ali Kashani Farid, Fereidoun Azizi, Mehdi Hedayati, Maryam S Daneshpour, Ahmad Reza Shamshiri and Fereydoun Siassi
    Citation: Lipids in Health and Disease 2010 9:96
    Content type: Research Published on:

  20. Pathological left ventricular (LV) hypertrophy frequently progresses to dilated heart failure with suppressed mitochondrial oxidative capacity. Dietary marine ω-3 polyunsaturated fatty acids (ω-3 PUFA) up-regu...

    Authors: Karen M O'Shea, David J Chess, Ramzi J Khairallah, Peter A Hecker, Biao Lei, Kenneth Walsh, Christine Des Rosiers and William C Stanley
    Citation: Lipids in Health and Disease 2010 9:95
    Content type: Research Published on:

  21. Dietary modification via caloric restriction is associated with multiple effects related to improved metabolic and cardiovascular health. However, a mandated reduction in kilocalories is not well-tolerated by ...

    Authors: Richard J Bloomer, Mohammad M Kabir, Robert E Canale, John F Trepanowski, Kate E Marshall, Tyler M Farney and Kelley G Hammond
    Citation: Lipids in Health and Disease 2010 9:94
    Content type: Research Published on:

  23. The role of inflammation in the pathogenesis and progression of atherosclerosis has been increasingly discussed. Although the seroepidemiological studies have suggested a relationship between Helicobacter pylori ...

    Authors: Halide S Akbas, Sebahat Basyigit, Inci Suleymanlar, Didem Kemaloglu, Serkan Koc, Fatih Davran, Ibrahim Demir and Gultekin Suleymanlar
    Citation: Lipids in Health and Disease 2010 9:92
    Content type: Research Published on:

  24. The search for sickle cell disease (SCD) prognosis biomarkers is a challenge. These markers identification can help to establish further therapy, later severe clinical complications and with patients follow-up...

    Authors: Magda O Seixas, Larissa C Rocha, Mauricio B Carvalho, Joelma F Menezes, Isa M Lyra, Valma ML Nascimento, Ricardo D Couto, Ájax M Atta, Mitermayer G Reis and Marilda S Goncalves
    Citation: Lipids in Health and Disease 2010 9:91
    Content type: Research Published on:

  25. β2-adrenoceptor (β2AR) gene polymorphism glutamine 27 glutamic acid (Gln27Glu) and Arg16Gly were reported to have an association with obesity and obesity related disorders in some population. We evaluated Gln2...

    Authors: Maha H Daghestani, Arjumand Warsy, Mazin H Daghestani, Ali N Al-odaib, Abdelmoneim Eldali, Nadia A Al-Eisa and Sabah Al-zhrani
    Citation: Lipids in Health and Disease 2010 9:90
    Content type: Research Published on:

  26. Oxidative stress produced by reactive oxygen species (ROS) has been linked to the development of several diseases such as cardiovascular, cancer, and neurodegenerative diseases. This study investigates the pos...

    Authors: Amel Nakbi, Wafa Tayeb, Samia Dabbou, Manel Issaoui, Abir K Grissa, Nabil Attia and Mohamed Hammami
    Citation: Lipids in Health and Disease 2010 9:89
    Content type: Research Published on:

  27. The objective of present study was to provide the pharmacological basis for the medicinal use of Morinda citrifolia Linn in dyslipidemia using the aqueous-ethanolic extracts of its fruits (Mc.Cr.F), leaves (Mc.Cr...

    Authors: Saf-ur Rehman Mandukhail, Nauman Aziz and Anwarul-Hassan Gilani
    Citation: Lipids in Health and Disease 2010 9:88
    Content type: Research Published on:

  28. Although advanced age is considered a risk factor for several diseases, the impact of gender on age-associated cardiovascular diseases, such as atherosclerotic processes and valvular diseases, remains not comp...

    Authors: Thiago M. C. Pereira, Breno V. Nogueira, Leandro C. F. Lima, Marcella L. Porto, Jose A. Arruda, Elisardo C. Vasquez and Silvana S. Meyrelles
    Citation: Lipids in Health and Disease 2010 9:87
    Content type: Research Published on:

  29. Both apolipoprotein (Apo) C-III gene polymorphism and alcohol consumption have been associated with increased serum triglyceride (TG) levels, but their interactions on serum TG levels are not well known. The p...

    Authors: Yin Ruixing, Li Yiyang, Li Meng, Li Kela, Long Xingjiang, Zhang Lin, Liu Wanying, Wu Jinzhen, Yang Dezhai and Lin Weixiong
    Citation: Lipids in Health and Disease 2010 9:86
    Content type: Research Published on:

  30. Dyslipidemia is a risk factor for incident type 2 diabetes; however, no study has specifically assessed the lipid ratios (i.e. total cholesterol (TC)/high density lipoprotein cholesterol (HDL-C) and triglyceri...

    Authors: Farzad Hadaegh, Masumeh Hatami, Maryam Tohidi, Parvin Sarbakhsh, Navid Saadat and Feridoun Azizi
    Citation: Lipids in Health and Disease 2010 9:85
    Content type: Research Published on:

  31. Sphingoid bases are formed from the precursors L-serine and palmitoyl-CoA-a reaction which is catalyzed by the serine-palmitoyltransferase (SPT). SPT metabolizes, besides palmitoyl-CoA also other acyl-CoAs but...

    Authors: Mariana Bertea, Markus F. Rütti, Alaa Othman, Jaqueline Marti-Jaun, Martin Hersberger, Arnold von Eckardstein and Thorsten Hornemann
    Citation: Lipids in Health and Disease 2010 9:84
    Content type: Research Published on:

  32. Since microvascular and macrovascular complications are reduced through strict glycemic control, this study carried out to identify the factors that affect glycemic control.

    Authors: Zeinab Ghazanfari, Shamsaddin Niknami, Fazlollah Ghofranipour, Bagher Larijani, Hamid Agha-Alinejad and Ali Montazeri
    Citation: Lipids in Health and Disease 2010 9:83
    Content type: Research Published on:

  33. A sedentary lifestyle increases the risk of developing cardiovascular disease, obesity, and diabetes. This phenomenon is supported by recent studies suggesting a chronic, low-grade inflammation status. Endotox...

    Authors: Fabio S Lira, Jose C Rosa, Gustavo D Pimentel, Hélio A Souza, Erico C Caperuto, Luiz C Carnevali Jr, Marília Seelaender, Ana R Damaso, Lila M Oyama, Marco T de Mello and Ronaldo V Santos
    Citation: Lipids in Health and Disease 2010 9:82
    Content type: Research Published on:

  34. The metabolic syndrome, known also as the insulin resistance syndrome, refers to the clustering of several risk factors for atherosclerotic cardiovascular disease. Dyslipidaemia is a hallmark of the syndrome a...

    Authors: Chia Hui Apphia Eu, Wai Yen Alfred Lim, So Ha Ton and Khalid bin Abdul Kadir
    Citation: Lipids in Health and Disease 2010 9:81
    Content type: Research Published on:

  35. Treatment guidelines recommend LDL-C as the primary target of therapy in patients with hypercholesterolemia. Moreover, combination therapies with lipid-lowering drugs that have different mechanisms of action a...

    Authors: Carlo M Rotella, Augusto Zaninelli, Cristina Le Grazie, Mary E Hanson and Gian Franco Gensini
    Citation: Lipids in Health and Disease 2010 9:80
    Content type: Research Published on:

  36. We have recently noted that ingestion of dietary lipid (in the form of heavy whipping cream) leads to greater oxidative stress than dietary carbohydrate (in the form of dextrose), when consumed in isocaloric a...

    Authors: Richard J Bloomer, Mohammad M Kabir, Kate E Marshall, Robert E Canale and Tyler M Farney
    Citation: Lipids in Health and Disease 2010 9:79
    Content type: Research Published on:

  38. Dietary 1(3)-behenoyl-2,3(1)-dioleoyl-rac-glycerol (BOO) has been reported to inhibit pancreatic lipase activity in vitro and suppress postprandial hypertriacylglycerolemia in humans. In the present study, the an...

    Authors: Makiko Kojima, Nobuhiko Tachibana, Takashi Yamahira, Satoshi Seino, Ayako Izumisawa, Nobuo Sagi, Toshiharu Arishima, Mitsutaka Kohno, Kiyoharu Takamatsu, Motohiko Hirotsuka and Ikuo Ikeda
    Citation: Lipids in Health and Disease 2010 9:77
    Content type: Research Published on:

  39. The weakening of the cardiovascular system associated with aging could be countered by increasing levels of physical activity and functional fitness. However, inconsistent findings have been found, and the var...

    Authors: Raul A Martins, Manuel T Veríssimo, Manuel J Coelho e Silva, Sean P Cumming and Ana M Teixeira
    Citation: Lipids in Health and Disease 2010 9:76
    Content type: Research Published on:

  40. The risk of cardiovascular disease is inversely correlated to level of plasma HDL-c. Moreover, reverse cholesterol transport (RCT) from peripheral tissues to the liver is the most widely accepted mechanism lin...

    Authors: Karima Bencharif, Laurence Hoareau, Ravi K Murumalla, Evelyne Tarnus, Frank Tallet, Roger G Clerc, Christophe Gardes, Maya Cesari and Régis Roche
    Citation: Lipids in Health and Disease 2010 9:75
    Content type: Research Published on:

  41. Frog skin has been sequentially and scientifically evaluated by our group for its wound healing efficiency. Owing to the complex structure of skin, attempts were being made to analyse the role of individual co...

    Authors: Venkat Raghavan K, Mary Babu, Rama Rajaram and Korrapati Purna Sai
    Citation: Lipids in Health and Disease 2010 9:74
    Content type: Research Published on:

  42. Lipid-enriched diets and oxidative stress are risk factors for the development of atherosclerosis. The effects of the methanolic (ME) and cyclohexane (CHE) extracts of the Pistacia vera nut, often included in the...

    Authors: Katerina A Marinou, Katerina Georgopoulou, George Agrogiannis, Theodore Karatzas, Dimitrios Iliopoulos, Apostolos Papalois, Achilles Chatziioannou, Prokopios Magiatis, Maria Halabalaki, Nektaria Tsantila, Leandros A Skaltsounis, Efstratios Patsouris and Ismene A Dontas
    Citation: Lipids in Health and Disease 2010 9:73
    Content type: Research Published on:

  43. In the present investigation we compared blood epinephrine (EPI), norepinephrine (NE), free fatty acids (FFA) and glycerol concentrations in response to a capsaicinoid supplement or placebo in healthy adults b...

    Authors: Richard J Bloomer, Robert E Canale, Sid Shastri and Sujata Suvarnapathki
    Citation: Lipids in Health and Disease 2010 9:72
    Content type: Research Published on:

  44. Intensive statin therapy decreases mortality and incidence of coronary events in patients after acute coronary syndrome (ACS). Recently it has been reported that spontaneous lipid levels remain clinically stab...

    Authors: Dagmar Vondrakova, Petr Ostadal and Andreas Kruger
    Citation: Lipids in Health and Disease 2010 9:71
    Content type: Research Published on:

  45. Nutritional control of gene regulation guides the transformation of smooth muscle cells (SMC) into foam cells in atherosclerosis. Oxidative stress has been reported in areas of lipid accumulation, activating p...

    Authors: Sonia Perales, Ma José Alejandre, Rogelio Palomino Morales, Carolina Torres and Ana Linares
    Citation: Lipids in Health and Disease 2010 9:70
    Content type: Research Published on:

  46. To evaluate the relationship between the low-density lipoprotein cholesterol (LDL-C)/high-density lipoprotein cholesterol (HDL-C) ratio and HDL subclass distribution and to further examine and discuss the pote...

    Authors: Li Tian, Yinghui Liu, Yang Qin, Shiyin Long, Yanhua Xu and Mingde Fu
    Citation: Lipids in Health and Disease 2010 9:69
    Content type: Research Published on:

  47. It was investigated whether dietary polyunsaturated fatty acids (PUFA) could influence colonic injury, tissue DNA damage, cytokines and myeloperoxidase activity (MPO) and plasma corticosterone in DSS-induced c...

    Authors: Karina V Barros, Roberta AN Xavier, Gilclay G Abreu, Carlos AR Martinez, Marcelo L Ribeiro, Alessandra Gambero, Patrícia O Carvalho, Claudia MO Nascimento and Vera LF Silveira
    Citation: Lipids in Health and Disease 2010 9:68
    Content type: Research Published on:

  49. Poor control of blood pressure leads to hypertension which is a major risk factor for development of cardiovascular disease. The present study aimed to explore possible mechanisms of elevation in blood pressur...

    Authors: Xin-Fang Leong, Mohd Rais Mustafa, Srijit Das and Kamsiah Jaarin
    Citation: Lipids in Health and Disease 2010 9:66
    Content type: Research Published on:

  50. Experimental evidences demonstrate that vegetable derived extracts inhibit cholesterol absorption in the gastrointestinal tract. To further explore the mechanisms behind, we modeled duodenal contents with seve...

    Authors: Mariona Jové, José CE Serrano, Maria Josep Bellmunt, Anna Cassanyé, Neus Anglès, Jordi Reguant, José R Morelló, Reinald Pamplona and Manuel Portero-Otín
    Citation: Lipids in Health and Disease 2010 9:65
    Content type: Research Published on:
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Lipids in Health and Disease

ISSN: 1476-511X