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  1. Sphingolipids are essential components of cell membranes, and many of them regulate vital cell functions. In particular, ceramide plays crucial roles in cell signaling processes. Two major actions of ceramides...

    Authors: Lide Arana, Patricia Gangoiti, Alberto Ouro, Miguel Trueba and Antonio Gómez-Muñoz
    Citation: Lipids in Health and Disease 2010 9:15
    Content type: Review Published on:

  2. Chronic inflammations, atherosclerosis and obesity, are major risk factors for cardiovascular diseases. Immune modulation of the inflammatory response has shown promise in animal models of atherogenesis and me...

    Authors: Aldar S Bourinbaiar and Vichai Jirathitikal
    Citation: Lipids in Health and Disease 2010 9:14
    Content type: Research Published on:

  4. Acute and chronic inflammation play essential roles in inflammatory/autoimmune conditions. Protective anti-inflammatory effects of the n-3 fatty acids docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA)...

    Authors: Weimin Kong, Jui-Hung Yen, Evros Vassiliou, Sabina Adhikary, Miguel G Toscano and Doina Ganea
    Citation: Lipids in Health and Disease 2010 9:12
    Content type: Research Published on:

  6. Exaggerated postprandial spikes in blood glucose and lipids induce proportional increases in oxidative stress, which acutely trigger impairment endothelial, inflammation and increased risk of future cardiovasc...

    Authors: Mahbubeh Setorki, Sedighe Asgary, Akram Eidi, Ali Haeri rohani and Majid KHazaei
    Citation: Lipids in Health and Disease 2010 9:10
    Content type: Research Published on:

  7. Polysaccharide from fuzi (FPS), a Chinese herbal medicine extract, has been demonstrated to exert lipid lowering affects. In this study we examined potential mechanisms underlying this affect, specifically alt...

    Authors: Xiongqing Huang, Juan Tang, Qin Zhou, Hanping Lu, Yiling Wu and Weikang Wu
    Citation: Lipids in Health and Disease 2010 9:9
    Content type: Research Published on:

  8. Apolipoprotein E is a polymorphic and multifunctional protein with numerous roles in lipoprotein metabolism. The three common isoforms apoE2, apoE3 and apoE4 show isoform-specific functional properties includi...

    Authors: Inga Kuhlmann, Anne Marie Minihane, Patricia Huebbe, Almut Nebel and Gerald Rimbach
    Citation: Lipids in Health and Disease 2010 9:8
    Content type: Review Published on:

  9. Omega-3 and -6 polyunsaturated fatty acids (LCPUFA), are important for good health conditions. They are present in membrane phospholipids.

    Authors: Angela M Rizzo, Gigliola Montorfano, Manuela Negroni, Laura Adorni, Patrizia Berselli, Paola Corsetto, Klaus Wahle and Bruno Berra
    Citation: Lipids in Health and Disease 2010 9:7
    Content type: Research Published on:

  10. Diabetes is a strong risk factor for cardiovascular disease (CVD).The relative role of various lipid measures in determining CVD risk in diabetic patients is still a subject of debate. We aimed to compare perf...

    Authors: Maryam Tohidi, Masumeh Hatami, Farzad Hadaegh, Maryam Safarkhani, Hadi Harati and Fereidoun Azizi
    Citation: Lipids in Health and Disease 2010 9:6
    Content type: Research Published on:

  11. The present study examined plasma lipid profiles in thirty patients suffered from acute viral hepatitis. Patients' blood samples were collected at both the debut and recovery of diseases. Thirty sex and age ma...

    Authors: Libo Luo, Xiangke Pu, Yongzhong Wang and Ning Xu
    Citation: Lipids in Health and Disease 2010 9:5
    Content type: Research Published on:

  12. Cholesterol administration has been reported to influence hepatic lipid metabolism in rats. In the present study, the effect of dietary cholesterol on hepatic activity and mRNA expression of the enzymes involv...

    Authors: Yu-Ming Wang, Bei Zhang, Yong Xue, Zhao-Jie Li, Jing-Feng Wang, Chang-Hu Xue and Teruyoshi Yanagita
    Citation: Lipids in Health and Disease 2010 9:4
    Content type: Research Published on:

  14. The mechanism of atherogenesis is not yet fully understood despite intense study in this area. The effects of high fat diet (HFD) on the changes of trace elements [iron (Fe), copper (Cu) and zinc (Zn)] in seve...

    Authors: Mohamed Anwar K Abdelhalim, Hisham A Alhadlaq and Sherif Abdelmottaleb Moussa
    Citation: Lipids in Health and Disease 2010 9:2
    Content type: Research Published on:

  15. Ceramide kinase (CERK) produces the bioactive lipid ceramide-1-phosphate (C1P) and is a key regulator of ceramide and dihydroceramide levels. It is likely that CERK and C1P play a role in inflammatory processe...

    Authors: Satoru Niwa, Nicole Urtz, Thomas Baumruker, Andreas Billich and Frédéric Bornancin
    Citation: Lipids in Health and Disease 2010 9:1
    Content type: Research Published on:

  16. Polyunsaturated fatty acids (PUFAs) form an important constituent of all the cell membranes in the body. PUFAs such as arachidonic acid (AA), eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) form pre...

    Authors: Undurti N Das and László G Puskás
    Citation: Lipids in Health and Disease 2009 8:61
    Content type: Hypothesis Published on:

  17. Circadian patterns of cardiovascular vulnerability were well characterized, with a peak incidence of acute myocardial infarction and stroke secondary to atherosclerosis in the morning, which showed the circadi...

    Authors: Likun Hou, Chao Lu, Yang Huang, Sifeng Chen, Luchun Hua and Ruizhe Qian
    Citation: Lipids in Health and Disease 2009 8:60
    Content type: Research Published on:

  18. The objective of this survey was to study the association between Helicobacter pylori infection and the severity of coronary atherosclerosis.

    Authors: En-Zhi Jia, Fu-Jun Zhao, Bo Hao, Tie-Bing Zhu, Lian-Sheng Wang, Bo Chen, Ke-Jiang Cao, Jun Huang, Wen-Zhu Ma, Zhi-Jian Yang and Guoxin Zhang
    Citation: Lipids in Health and Disease 2009 8:59
    Content type: Research Published on:

  19. Mainly dependent on hormone-sensitive lipase, lipolysis is differently impaired between fat depots in human obesity. Perilipin A expression is a critical element in adipocyte lipolysis. The present study aimed...

    Authors: Hind Ray, Claudie Pinteur, Vincent Frering, Michel Beylot and Valérie Large
    Citation: Lipids in Health and Disease 2009 8:58
    Content type: Research Published on:

  21. This trial compares the efficacy of administering a combination of ezetimibe plus fenofibrate as an alternative to statin monotherapy for the treatment of dyslipidemia. In this randomized, unblinded crossover ...

    Authors: Shoba Sujana Kumar, Karen A Lahey, Andrew Day and Stephen A LaHaye
    Citation: Lipids in Health and Disease 2009 8:56
    Content type: Research Published on:

  22. Atherosclerosis is a chronic disorder of the arterial wall that starts by formation of fatty streaks and gradually evolves into atherosclerotic plaques. High-density lipoproteins (HDL) blood levels are inverse...

    Authors: Harman D Kaur and Mohinder P Bansal
    Citation: Lipids in Health and Disease 2009 8:55
    Content type: Research Published on:

  23. Unsaturated fatty acids (UFAs) exhibit in vitro cytotoxicity against many malignant cell lines and yield decreased cancer incidence and reduced tumor growth in animal models. But clinical and animal studies to da...

    Authors: David E Scheim
    Citation: Lipids in Health and Disease 2009 8:54
    Content type: Research Published on:

  24. Cholesterol gallstone disease (GS) is highly prevalent among Hispanics and American Indians. In GS, the pool of bile acids (BA) is decreased, suggesting that BA absorption is impaired. In Caucasian GS patients...

    Authors: Jorge Herrera, Ludwig Amigo, Constanze Husche, Carlos Benítez, Silvana Zanlungo, Dieter Lütjohann, Juan Francisco Miquel and Flavio Nervi
    Citation: Lipids in Health and Disease 2009 8:53
    Content type: Research Published on:

  25. Genome-wide association studies have identified numerous single nucleotide polymorphisms (SNPs) affecting high density lipoprotein (HDL) or low density lipoprotein (LDL) cholesterol levels; these SNPs may cont...

    Authors: James Ronald, Ramakrishnan Rajagopalan, Jane E Ranchalis, Julieann K Marshall, Thomas S Hatsukami, Patrick J Heagerty and Gail P Jarvik
    Citation: Lipids in Health and Disease 2009 8:52
    Content type: Research Published on:

  27. CETP is a plasma protein that modulates atherosclerosis risk through its HDL-cholesterol reducing action. The aim of this work was to examine the effect of the PPARα agonist, ciprofibrate, on the CETP gene exp...

    Authors: Eliete JB Bighetti, Patrícia R Patrício, Andrea C Casquero, Jairo A Berti and Helena CF Oliveira
    Citation: Lipids in Health and Disease 2009 8:50
    Content type: Research Published on:

  28. Detergents are often used to isolate proteins, lipids as well as "detergent-resistant membrane domains" (DRMs) from cells. Different detergents affect different membrane structures according to their physico-c...

    Authors: Ulrike Jakop, Beate Fuchs, Rosmarie Süß, Gudrun Wibbelt, Beate Braun, Karin Müller and Jürgen Schiller
    Citation: Lipids in Health and Disease 2009 8:49
    Content type: Research Published on:

  29. The aim of the study was to evaluate the association of immunoglobulin G type of autoantibodies to oxidized low-density lipoprotein (oxLDL-lgG) and oxLDL-lgM with the progression of esophageal squamous cell ca...

    Authors: Yutao Diao, Hao Li, Huiqing Li, Yingzhi Zhou, Qing Ma, Yan Wang and Dong Li
    Citation: Lipids in Health and Disease 2009 8:48
    Content type: Research Published on:

  30. Authors: Javad Zavvar Reza, Mahmoud Doosti, Masoud Salehipour, Malehieh Packnejad, Majed Mojarrad and Mansour Heidari
    Citation: Lipids in Health and Disease 2009 8:47
    Content type: Erratum Published on:

    The original article was published in Lipids in Health and Disease 2009 8:38

  31. Amyloid-β is recognized as the major constituent of senile plaque found in subjects with Alzheimer's disease. However, there is increasing evidence that in a physiological context amyloid-β may serve as regula...

    Authors: Susan Galloway, Ryusuke Takechi, Menuka MS Pallebage-Gamarallage, Satvinder S Dhaliwal and John CL Mamo
    Citation: Lipids in Health and Disease 2009 8:46
    Content type: Research Published on:

  32. Although consumption of various plant sterol (PS)-enriched beverages is effective in lowering plasma cholesterol, the lipid-lowering potential of PS in a soymilk format has not been investigated thoroughly. Th...

    Authors: Todd C Rideout, Yen-Ming Chan, Scott V Harding and Peter JH Jones
    Citation: Lipids in Health and Disease 2009 8:45
    Content type: Research Published on:

  34. The β2-adrenergic receptor (BAR2) is the main lipolytic receptor in white human adipose tissue. There is a functional glutamine 27 glutamic acid (Gln27Glu, rs 1042714) polymorphism in its gene, which has been var...

    Authors: Tarja Kunnas, Riikka Lahtio, Marja-Leena Kortelainen, Anne Kalela and Seppo T Nikkari
    Citation: Lipids in Health and Disease 2009 8:43
    Content type: Short paper Published on:

  35. Metabolic syndrome is associated with subsequent development of cardiovascular diseases and type 2 diabetes. It is characterized by reduced response to insulin, central obesity, and dyslipidemia. Intake of pla...

    Authors: Ehud Ziv, Natan Patlas, Rony Kalman, Dori Pelled, Yael Herzog, Tali Dror and Tzafra Cohen
    Citation: Lipids in Health and Disease 2009 8:42
    Content type: Research Published on:

  36. Ezetimibe (Zetia®) is a potent inhibitor of cholesterol absorption that has been approved for the treatment of hypercholesterolemia. Statin, an inhibitor of cholesterol synthesis, is the first-choice drug to redu...

    Authors: Minako Yamaoka-Tojo, Taiki Tojo, Rie Kosugi, Yuko Hatakeyama, Yuki Yoshida, Yoji Machida, Naoyoshi Aoyama, Takashi Masuda and Tohru Izumi
    Citation: Lipids in Health and Disease 2009 8:41
    Content type: Research Published on:

  37. There is increasing interest in natural treatments to control dyslipidemia and reduce the risk of cardiovascular disease. Previous studies have demonstrated the beneficial effects of soy yogurt fermented with Ent...

    Authors: Daniela CU Cavallini, Dulcinéia SP Abdalla, Regina C Vendramini, Raquel Bedani, Laura Q Bomdespacho, Nadiége D Pauly-Silveira, Graciela F de Valdez and Elizeu A Rossi
    Citation: Lipids in Health and Disease 2009 8:40
    Content type: Research Published on:

  38. Atherosclerosis which results from gradual deposition of lipids in medium and large arteries is a leading cause of mortality worldwide. The objective of this study was to determine the effect of apple juice on...

    Authors: Mahbubeh Setorki, Sedighe Asgary, Akram Eidi, Ali Haeri rohani and Nafiseh Esmaeil
    Citation: Lipids in Health and Disease 2009 8:39
    Content type: Research Published on:

  39. One of the most important factors in the initiation and progression of atherosclerosis is the default in macrophage cholesterol homeostasis. Many genes and transcription factors such as Peroxisome Proliferator...

    Authors: Javad Zavvar Reza, Mahmoud Doosti, Masoud salehipour, Malehieh PackneJad, Majed Mojarrad, Mansour Heidari and Effat S Emamian
    Citation: Lipids in Health and Disease 2009 8:38
    Content type: Research Published on:

    The Erratum to this article has been published in Lipids in Health and Disease 2009 8:47

  40. Fatty acid composition of serum lipids and adipose tissue triacylglycerols (AT-TAG) partly reflect dietary fatty acid intake. The fatty acid composition is, besides the diet, also influenced by desaturating en...

    Authors: Eva Warensjö, Magdalena Rosell, Mai-Lis Hellenius, Bengt Vessby, Ulf De Faire and Ulf Risérus
    Citation: Lipids in Health and Disease 2009 8:37
    Content type: Short paper Published on:

  41. The purpose of the present investigation was to determine the effects of EPA/DHA supplementation on resting and exercise-induced inflammation and oxidative stress in exercise-trained men. Fourteen men suppleme...

    Authors: Richard J Bloomer, Douglas E Larson, Kelsey H Fisher-Wellman, Andrew J Galpin and Brian K Schilling
    Citation: Lipids in Health and Disease 2009 8:36
    Content type: Research Published on:

  42. Peroxisome proliferator-activated receptor (PPAR)γ is a key regulator in adipose tissue. The rare variant Pro12Ala of PPARγ2 is associated with a decreased risk of insulin resistance. Being dietary PPARγ ligan...

    Authors: J Herrmann, D Rubin, R Häsler, U Helwig, M Pfeuffer, A Auinger, C Laue, P Winkler, S Schreiber, D Bell and J Schrezenmeir
    Citation: Lipids in Health and Disease 2009 8:35
    Content type: Research Published on:

  43. The objective was to investigate in a group of obese subjects the course in skeletal muscle phospholipid (SMPL) fatty acids (FA) during a 24-weeks weight maintenance program, which was preceded by a successful...

    Authors: Steen B Haugaard, Allan Vaag, Huiling Mu and Sten Madsbad
    Citation: Lipids in Health and Disease 2009 8:34
    Content type: Research Published on:

  44. N-3 Polyunsaturated fatty acids have been shown to have potential beneficial effects for chronic diseases including cancer, insulin resistance and cardiovascular disease. Eicosapentaenoic acid (EPA) and docosa...

    Authors: Breanne M Anderson and David WL Ma
    Citation: Lipids in Health and Disease 2009 8:33
    Content type: Review Published on:

  45. We have recently reported that the dietary supplement Meltdown® increases plasma norepinephrine (NE), epinephrine (EPI), glycerol, free fatty acids (FFA), and metabolic rate in men. However, in that investigation...

    Authors: Richard J Bloomer, Robert E Canale, Megan M Blankenship, Kelley G Hammond, Kelsey H Fisher-Wellman and Brian K Schilling
    Citation: Lipids in Health and Disease 2009 8:32
    Content type: Research Published on:

  46. The metabolic syndrome (MetS) is a cluster of metabolic abnormalities comprising visceral obesity, dyslipidaemia and insulin resistance (IR). With the onset of IR, the expression of lipoprotein lipase (LPL), a...

    Authors: Wai Yen Alfred Lim, Yoke Yin Chia, Shih Yeen Liong, So Ha Ton, Khalid Abdul Kadir and Sharifah Noor Akmal Syed Husain
    Citation: Lipids in Health and Disease 2009 8:31
    Content type: Research Published on:

  47. The aim of this work was to assess the effect of chronic administration of protonated nanostructured aluminosilicate (NSAS) on the plasma cholesterol levels and development of atherosclerotic lesions in Apolip...

    Authors: Olena Sivak, Jerry Darlington, Pavel Gershkovich, Panayiotis P Constantinides and Kishor M Wasan
    Citation: Lipids in Health and Disease 2009 8:30
    Content type: Research Published on:

  48. Changes in lipid profile have long been associated with malignancies as lipids play a key role in maintenance of cell integrity. This study evaluated the alterations in extended lipid profile in untreated pati...

    Authors: Ravi Mehrotra, Shruti Pandya, Ajay Kumar Chaudhary, Himanshu Pratap Singh, Ritesh Kumar Jaiswal, Mangal Singh, SC Gupta and Mamta Singh
    Citation: Lipids in Health and Disease 2009 8:29
    Content type: Research Published on:

  49. The metabolism of dietary fatty acids in human has been measured so far using human blood cells and stable-isotope labeled fatty acids, however, no direct data was available for human peripheral tissues and ot...

    Authors: Satoshi Yoshida, Qin-Zeng Zhang, Shu Sakuyama and Satoshi Matsushima
    Citation: Lipids in Health and Disease 2009 8:28
    Content type: Research Published on:
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Lipids in Health and Disease

ISSN: 1476-511X