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  1. A new water-based topical formulation is presented that aims at providing good penetration properties for both lipophilic and hydrophilic drugs with as small a disturbance of the skin barrier function as possi...

    Authors: Mats Silvander, Lovisa Ringstad, Ruby Ghadially and Thomas Sköld
    Citation: Lipids in Health and Disease 2006 5:12
  2. Apolipoprotein AV (ApoAV) gene variant, -1131T>C, is associated with increased triglyceride concentrations in all ethnic groups studied. An MseI based RFLP analysis is the most commonly used method for genotyping...

    Authors: Kirsten J Ward, Sian Ellard, Chittaranjan S Yajnik, Timothy M Frayling, Andrew T Hattersley, Prathyusha NS Venigalla and Giriraj R Chandak
    Citation: Lipids in Health and Disease 2006 5:11
  3. Herein, we expand our previous work on the effects of long chain polyunsaturated fatty acids (LC-PUFA) on the murine hepatic transcriptome using novel statistical and bioinformatic approaches for evaluating mi...

    Authors: Alvin Berger, Matthew A Roberts and Bruce Hoff
    Citation: Lipids in Health and Disease 2006 5:10
  4. previous studies have indicated on association between shift work and lipid profile disturbances. Lipid profile disturbances could be due to internal desynchronization. The aim of this study was to analyze whe...

    Authors: Masoumeh Ghiasvand, Ramin Heshmat, Reza Golpira, Vahid Haghpanah, Ali Soleimani, Payman Shoushtarizadeh, Seyed Mohammad Tavangar and Bagher Larijani
    Citation: Lipids in Health and Disease 2006 5:9
  5. The Friedewald formula (LDL-F) for the estimation of low-density lipoprotein (LDL) cholesterol concentrations is the most often used formula in clinical trials and clinical practice. However, much concern has ...

    Authors: Irene Gazi, Vasilis Tsimihodimos, Theodosios D Filippatos, Vasilios G Saougos, Eleni T Bairaktari, Alexandros D Tselepis and Moses Elisaf
    Citation: Lipids in Health and Disease 2006 5:8
  6. There is an increase in obesity among the population of industrialized countries, and dietary supplementation with Conjugated Linoleic Acid (CLA) has been reported to lower body fat mass. However, weight loss ...

    Authors: Jameela Banu, Arunabh Bhattacharya, Mizanur Rahman, Marianne O'Shea and Gabriel Fernandes
    Citation: Lipids in Health and Disease 2006 5:7
  7. A high dietary intake of n-6 compared to n-3 fatty acids (FAs) may promote the production of pro-inflammatory eicosanoids and cytokines. In two recent studies, short-term (10-day) duodenal administration of n-...

    Authors: Tormod Bjørkkjær, Johan G Brun, Merete Valen, Gülen Arslan, Ragna Lind, Linn A Brunborg, Arnold Berstad and Livar Frøyland
    Citation: Lipids in Health and Disease 2006 5:6
  8. The strong causal role of hypercholesterolaemia on the progression of atherosclerosis and subsequently on the development of cardiovascular disease is well described. Main aim of this study was to evaluate the...

    Authors: George A Milias, Demosthenes B Panagiotakos, Christos Pitsavos, Dimitra Xenaki, George Panagopoulos and Christodoulos Stefanadis
    Citation: Lipids in Health and Disease 2006 5:5
  9. Liver plays a key role in the metabolism of plasma apolipoproteins, endogenous lipids and lipoproteins. Hepatocellular carcinoma (HCC) is one of the most common fatal malignant tumors in China and in other Sou...

    Authors: Jingting Jiang, Peter Nilsson-Ehle and Ning Xu
    Citation: Lipids in Health and Disease 2006 5:4
  10. The heart is rich in cardiolipin, a phospholipid acylated in four sites, predominately with linoleic acid. Whether or not aging alters the composition of cardiolipin acyl chains is controversial. We therefore ...

    Authors: Ho-Joo Lee, Jana Mayette, Stanley I Rapoport and Richard P Bazinet
    Citation: Lipids in Health and Disease 2006 5:2
  11. Homocysteine is an independent risk factor for cardiovascular diseases. It is also known to be associated with a variety of complex disorders. While there are a large number of independent studies implicating ...

    Authors: Priyanka Sharma, RD Senthilkumar, Vani Brahmachari, Elayanambi Sundaramoorthy, Anubha Mahajan, Amitabh Sharma and Shantanu Sengupta
    Citation: Lipids in Health and Disease 2006 5:1
  12. Dietary intervention trials rely on self-reported measures of intake for assessment of energy and macronutrient composition. Dietary fat intake is of particular interest due to strong associations with pathoph...

    Authors: Sally D Poppitt, Paul Kilmartin, Paul Butler and Geraldine F Keogh
    Citation: Lipids in Health and Disease 2005 4:30
  13. 13-Methyltetradecanoic acid (13-MTD), an iso-C15 branched- chain saturated fatty acid, has been shown to induce apoptotic cell death of numerous human cancer cells. However, the mechanism for the induction of ...

    Authors: Sawitree Wongtangtintharn, Hirosuke Oku, Hironori Iwasaki, Masashi Inafuku, Takayoshi Toda and Teruyoshi Yanagita
    Citation: Lipids in Health and Disease 2005 4:29
  14. Cholesterol ester storage disease (CESD) is an autosomal recessive illness that results from mutations in the LIPA gene encoding lysosomal acid lipase. CESD patients present in childhood with hepatomegaly and dys...

    Authors: Venu T Tadiboyina, Dora M Liu, Brooke A Miskie, Jian Wang and Robert A Hegele
    Citation: Lipids in Health and Disease 2005 4:26
  15. Oxidative modification of low-density lipoprotein (LDL) is a key event in the oxidation hypothesis of atherogenesis. Some in vitro experiments have previously suggested that high-density lipoprotein (HDL) co-incu...

    Authors: T Solakivi, O Jaakkola, A Salomäki, N Peltonen, S Metso, T Lehtimäki, H Jokela and ST Nikkari
    Citation: Lipids in Health and Disease 2005 4:25
  16. Postprandial lipemia is an independent risk factor for coronary heart disease. Single bouts of moderate exercise may lower this risk, but the minimum duration of moderate intensity exercise that still lowers p...

    Authors: Martina Pfeiffer, Tanja Ludwig, Caspar Wenk and Paolo C Colombani
    Citation: Lipids in Health and Disease 2005 4:24
  17. In man, elevated levels of plasma lipoprotein (a)(Lp(a)) is a cardiovascular risk factor, and oxidized phospholipids are believed to play a role as modulators of inflammatory processes such as atherosclerosis....

    Authors: Knut A Eliassen, Bjørn P Brodal, Aud Svindland, Harald Osmundsen, Helle Rønning, Srdjan Djurovic and Kåre Berg
    Citation: Lipids in Health and Disease 2005 4:23
  18. In the present study, the effects of subchronic treatments (4 weeks) of hypercholesterolemic (single) and diabetic-hypercholesterolemic (combined) rats with 4 (3H) quinazolinone and 2 halogenated derivatives (...

    Authors: Fawzia M Refaie, Amr Y Esmat, Soad M Abdel Gawad, Aida M Ibrahim and Mona A Mohamed
    Citation: Lipids in Health and Disease 2005 4:22
  19. The metabolic syndrome (MetS), as well as postprandial hypertriglyceridemia, is associated with coronary heart disease. This study aimed to evaluate the postprandial lipemia after oral fat tolerance test (OFTT...

    Authors: Genovefa D Kolovou, Katherine K Anagnostopoulou, Antonis N Pavlidis, Klelia D Salpea, Stella A Iraklianou, Konstantinos Tsarpalis, Dimitris S Damaskos, Athanasios Manolis and Dennis V Cokkinos
    Citation: Lipids in Health and Disease 2005 4:21
  20. Reference data for plasma lipids and blood pressure are not available for Asian Indian adolescents. This study aimed to develop representative age- and sex- specific percentile reference data for serum lipids ...

    Authors: Malini Madhavan, Ravindra M Pandey, Anoop Misra, Naval K Vikram, Vibha Dhingra, Kalpana Luthra and Jasjeet S Wasir
    Citation: Lipids in Health and Disease 2005 4:20
  21. In order to investigate the effects of lead exposure on risk of cardiovascular disease during occupational exposure to this metal, plasma cholesterol and its fractions as high-density liporotein (HDL), low-den...

    Authors: Oladipo Ademuyiwa, Regina Ngozi Ugbaja, Florence Idumebor and Olugbenga Adebawo
    Citation: Lipids in Health and Disease 2005 4:19
  22. Butyrylcholinesterase is an enzyme that may serve as a marker of metabolic syndrome. We (a) measured its level in persons with diabetes mellitus, (b) constructed a family tree of the enzyme using nucleotide se...

    Authors: GR Sridhar, G Nirmala, Allam Apparao, AS Madhavi, S Sreelatha, J Sudha Rani and P Vijayalakshmi
    Citation: Lipids in Health and Disease 2005 4:18
  23. NPC1L1 encodes a putative intestinal sterol transporter which is the likely target for ezetimibe, a new type of lipid-lowering medication. We previously reported rare non-synonymous mutations in NPC1L1 in an indi...

    Authors: Robert A Hegele, Justin Guy, Matthew R Ban and Jian Wang
    Citation: Lipids in Health and Disease 2005 4:16
  24. Abstract Hyperlipidemia and increased degree of oxidative stress are among the important risk factors for Atherosclerosis in renal transplant recipients (RTR). The Medical treatment of hyperlipidemia in RTR be...

    Authors: Abbas Jabbari, Hassan Argani, Amir Ghorbanihaghjo and Reza Mahdavi
    Citation: Lipids in Health and Disease 2005 4:11
  25. The requirement of cholesterol for internalization of eukaryotic pathogens like protozoa (Leishmaniasis, Malaria and Toxoplasmosis) and the exchange of cholesterol along with other metabolites during reproduction...

    Authors: Devendra Bansal, Harinderpal Singh Bhatti and Rakesh Sehgal
    Citation: Lipids in Health and Disease 2005 4:10
  26. Polyunsaturated fatty acids (PUFA) are thought to play important roles in inflammation. The n-3 series is considered as anti-inflammatory, and some studies have reported increased plasma n-3 polyunsaturated fa...

    Authors: Tiina Solakivi, Olli Jaakkola, Anne Kalela, Mari Pispa, Anne Salomäki, Terho Lehtimäki, Matti Höyhtyä, Hannu Jokela and Seppo T Nikkari
    Citation: Lipids in Health and Disease 2005 4:8
  27. Metabolic syndrome is a collection of associated conditions such as dyslipidemia, high blood pressure, impaired glucose tolerance and tendency to develop fat around the abdomen. It is now well known that indiv...

    Authors: Demosthenes B Panagiotakos and Evangelos Polychronopoulos
    Citation: Lipids in Health and Disease 2005 4:7
  28. This study tested the hypothesis that human macrophages have the ability to modify oxidation products in LDL and oxidized LDL (oxLDL) via a cellular antioxidant defence system. While many studies have focused ...

    Authors: Lillemor Mattsson Hultén, Christina Ullström, Alexandra Krettek, David van Reyk, Stefan L Marklund, Claes Dahlgren and Olov Wiklund
    Citation: Lipids in Health and Disease 2005 4:6
  29. Autotaxin (ATX, NPP-2), originally purified as a potent tumor cell motility factor, is now known to be the long-sought plasma lysophospholipase D (LPLD). The integrity of the enzymatic active site, including t...

    Authors: Timothy Clair, Eunjin Koh, Malgorzata Ptaszynska, Russell W Bandle, Lance A Liotta, Elliott Schiffmann and Mary L Stracke
    Citation: Lipids in Health and Disease 2005 4:5
  30. Protease inhibitors are known to alter the lipid profiles in subjects treated for HIV/AIDS. However, the magnitude of this effect on plasma lipoproteins and lipids has not been adequately quantified.

    Authors: Adrian R Levy, Lawrence McCandless, P Richard Harrigan, Robert S Hogg, Greg Bondy, Uchenna H Iloeje, Jayanti Mukherjee and Julio S Montaner
    Citation: Lipids in Health and Disease 2005 4:4
  31. Studies in rodents and some studies in humans have shown that conjugated linoleic acid (CLA), especially its trans-10, cis-12 isomer, reduces body fat content. However, some but not all studies in mice and humans...

    Authors: Ed Wargent, Matthew V Sennitt, Claire Stocker, Andrew E Mayes, Louise Brown, Jacqueline O'Dowd, Steven Wang, Alexandra WC Einerhand, Inge Mohede, Jonathan RS Arch and Michael A Cawthorne
    Citation: Lipids in Health and Disease 2005 4:3
  32. Transport of fatty acids within the cytosol of adipocytes and their subsequent assimilation into lipid droplets has been thoroughly investigated; however, the mechanism by which fatty acids are transported acr...

    Authors: Larissa C Wilsie, Shree Chanchani, Deepti Navaratna and Robert A Orlando
    Citation: Lipids in Health and Disease 2005 4:2
  33. Apolipoprotein A-V (Apo A-V) gene has recently been identified as a new apolipoprotein involved in triglyceride metabolism. A single nucleotide polymorphism (SNP3) located in the gene promoter (-1131) was asso...

    Authors: Raja Chaaba, Nebil Attia, Sonia Hammami, Maha Smaoui, Sylvia Mahjoub, Mohamed Hammami and Ahmed Slaheddine Masmoudi
    Citation: Lipids in Health and Disease 2005 4:1
  34. To determine the correlates of serum lipoprotein (a) (Lp(a)) in children and adolescents in the United States.

    Authors: Thomas O Obisesan, Muktar H Aliyu, Abayomi S Adediran, Vernon Bond, Celia J Maxwell and Charles N Rotimi
    Citation: Lipids in Health and Disease 2004 3:29
  35. The lipoprotein lipase (LPL) hydrolyses circulating triacylglycerol-rich lipoproteins. Thereby, LPL acts as a metabolic gate-keeper for fatty acids partitioning between adipose tissue for storage and skeletal ...

    Authors: Florence Gondret, Sanjay B Jadhao, Marie Damon, Patrick Herpin, Céline Viglietta, Louis-Marie Houdebine and Jean-François Hocquette
    Citation: Lipids in Health and Disease 2004 3:27
  36. The response of serum cholesterol to diet may be affected by the apolipoprotein E (APOE) ε2/ε3/ε4 polymorphism, which also is a significant predictor of variation in the risk of coronary heart disease (CHD) and C...

    Authors: Elisabeth Strandhagen, Henrik Zetterberg, Nibia Aires, Mona Palmér, Lars Rymo, Kaj Blennow and Dag S Thelle
    Citation: Lipids in Health and Disease 2004 3:26
  37. Conjugated fatty acid, the general term of positional and geometric isomers of polyunsaturated fatty acids with conjugated double bonds, has attracted considerable attention because of its potentially benefici...

    Authors: Keisuke Arao, Yu-Ming Wang, Nao Inoue, Junichi Hirata, Jae-Young Cha, Koji Nagao and Teruyoshi Yanagita
    Citation: Lipids in Health and Disease 2004 3:24

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