Positive association of the hepatic lipase gene polymorphism c.514C > T with estrogen replacement therapy response

Table 8 Results of the paired-samples t-tests for lipoproteins before and after treatment, by allele

Allele	Variable mg/dL	N	Mean	SD	t-test	p
C	TotalChol	59	210.93	45.26	0.20	0.85
	TotalChol2	59	209.71	39.06
T	TotalChol	57	209.67	45.68	0.08	0.93
	TotalChol2	57	209.11	47.08
C	HDL-C	59	57.53	12.16	1.37	0.18
	HDL-C2	59	55.80	14.24
T	HDL-C	57	60.42	14.52	0.50	0.62
	HDL-C2	57	59.79	14.35
C	LDL-C	59	126.44	37.70	-0.20	0.84
	LDL-C2	59	127.44	36.44
T	LDL-C	57	113.44	38.62	-1.39	0.17
	LDL-C2	57	123.32	39.58
C	TG	59	134.47	58.15	1.85	0.07
	TG2	59	121.47	59.69
T	TG	57	141.79	71.95	2.46	0.02
	TG2	57	122.68	72.88

TotalChol: total pre-treatment cholesterol; HDL-C: pre-treatment high-density lipoprotein cholesterol; LDL-C: pre-treatment low-density lipoprotein cholesterol; TG: pre-treatment triglycerides; TotalChol2: total post-treatment cholesterol; HDL-C2: post-treatment high-density lipoprotein cholesterol; LDL-C2: post-treatment low-density lipoprotein cholesterol; TG2: post-treatment triglycerides; CC: homozygous major-allele genotype; CT: heterozygous genotype; TT: homozygous minor-allele genotype.

ISSN: 1476-511X