A new ratio for better predicting future death/myocardial infarction than standard lipid measurements in women >50 years undergoing coronary angiography: the apolipoprotein A1 remnant ratio (Apo A1/ [VLDL3+IDL])

May, Heidi T; Nelson, John R; Kulkarni, Krishnaji R; Anderson, Jeffrey L; Horne, Benjamin D; Bair, Tami L; Muhlestein, Joseph B

doi:10.1186/1476-511X-12-55

Lipids in Health and Disease

Table 2 Death/MI event rates at 1 and 3 years among lipid and lipoprotein tertiles

From: A new ratio for better predicting future death/myocardial infarction than standard lipid measurements in women >50 years undergoing coronary angiography: the apolipoprotein A1 remnant ratio (Apo A1/ [VLDL₃+IDL])

Outcome	Tertile 1	Tertile 2	Tertile 3	p-trend
Apo A1/(VLDL ₃ -C+IDL-C)
1 year Death/MI	9.7% (23)	7.6% (18)	6.3% (15)	0.17
3 year Death/MI	17.3% (41)	15.6% (37)	9.3% (22)	0.01
Apo A1
1 year Death/MI	11.4% (27)	5.5% (13)	6.8% (16)	0.06
3 year Death/MI	21.1% (50)	9.3% (22)	11.8% (28)	0.004
Apo B
1 year Death/MI	6.3% (15)	10.1% (24)	7.2% (17)	0.27
3 year Death/MI	13.9% (33)	16.0% (38)	12.2% (29)	0.49
Apo B/A1
1 year Death/MI	7.2% (17)	5.1% (12)	11.4% (27)	0.03
3 year Death/MI	12.2% (29)	11.4% (27)	18.6% (44)	0.05
HDL-C
1 year Death/MI	8.4% (20)	6.6% (15)	8.5% (21)	0.98
3 year Death/MI	18.6% (44)	10.2% (23)	13.3% (33)	0.10
Triglycerides
1 year Death/MI	7.7% (18)	9.2% (22)	6.8% (16)	0.72
3 year Death/MI	12.3% (29)	15.4% (37)	14.4% (34)	0.52
LDL-C
1 year Death/MI	8.3% (20)	8.2% (19)	7.1% (17)	0.63
3 year Death/MI	16.3% (39)	12.9% (30)	13.0% (31)	0.31
non-HDL-C
1 year Death/MI	6.8% (16)	10.2% (24)	6.7% (16)	0.96
3 year Death/MI	14.0% (33)	16.6% (39)	11.7% (28)	0.46
Triglycerides/HDL-C Ratio
1 year Death/MI	7.9% (23)	9.1% (21)	6.4% (12)	0.64
3 year Death/MI	11.6% (34)	17.2% (40)	13.9% (26)	0.37
VLDL ₃ -C+IDL-C
1 year Death/MI	6.8% (17)	7.4% (16)	9.3% (23)	0.29
3 year Death/MI	11.6% (29)	15.8% (34)	15.0% (37)	0.27
Total Cholesterol/HDL-C Ratio
1 year Death/MI	8.9% (21)	7.6% (18)	7.2% (17)	0.78
3 year Death/MI	13.5% (32)	12.6% (30)	16.1% (38)	0.52
HDL-C/(VLDL ₃ -C+IDL-C)
1 year Death/MI	10.6% (25)	6.3% (15)	6.7% (16)	0.12
3 year Death/MI	19.1% (45)	13.0% (31)	10.1% (24)	0.005
LDL-C/HDL-C
1 year Death/MI	9.7% (23)	5.5% (13)	8.4% (20)	0.61
3 year Death/MI	14.3% (34)	11.4% (27)	16.5% (39)	0.51

Apo: apolipoprotein; HDL-C: high density lipoprotein cholesterol; IDL-C: intermediate density lipoprotein cholesterol; LDL-C: low density lipoprotein cholesterol; VLDL-C: very low density lipoprotein₃ cholesterol.

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ISSN: 1476-511X

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