| Exam 1 (1999–2001) | Exam 2 (2002–2005) | Exam 3 (2005–2008) | Exam 4 (2008–2011) | p-value for trend |
---|---|---|---|---|---|
Male | Â | Â | Â | Â | Â |
  TC†| 5.14 (5.13-5.16) | 5.07 (5.06-5.09) | 5.00 (4.98-5.01) | 4.93 (4.91-4.94) | <0.001 |
  HDL-C†| 0.937 (0.935-0.938) | 0.976 (0.975-0.978) | 1.015 (1.014-1.017) | 1.055 (1.053-1.056) | <0.001 |
  TG†| 1.97 (1.96-1.98) | 1.94 (1.92-1.95) | 1.91 (1.88-1.92) | 1.87 (1.86-1.89) | <0.001 |
  Non-HDL-C†| 4.20 (4.19-4.22) | 4.09 (4.08-4.10) | 3.97 (3.96-3.99) | 3.86 (3.85-3.87) | <0.001 |
  TG/HDL-C | 2.33 (2.31-2.34) | 2.21 (2.19-2.22) | 2.08 (2.07-2.10) | 1.96 (1.95-1.98) | <0.001 |
  TC/HDL-C | 5.74 (5.73-5.76) | 5.46 (5.44-5.47) | 5.16 (5.15-5.18) | 4.88 (4.86-4.9) | <0.001 |
  FPG†| 5.14 (5.12-5.16) | 5.30 (5.28-5.32) | 5.45 (5.44-5.47) | 5.62 (5.60-5.63) | 0.014 |
  BMI (kg/m2) | 25.85 (25.79-25.9) | 26.36 (26.31-26.41) | 26.85 (26.8-26.91) | 27.37 (27.32-27.43) | <0.001 |
Female | Â | Â | Â | Â | Â |
  TC†| 5.19 (5.16-5.21) | 5.14 (5.12-5.17) | 5.09 (5.07-5.11) | 5.05(5.03-5.08) | <0.001 |
  HDL-C†| 1.0945 (1.094-1.095) | 1.149 (1.148-1.150) | 1.203 (1.202-1.204) | 1.258 (1.257-1.259) | <0.001 |
  TG†| 1.63 (1.62-1.65) | 1.62 (1.61-1.64) | 1.61 (1.59-1.62) | 1.60 (1.59-1.61) | <0.001 |
  Non-HDL-C†| 4.09 (4.07-4.11) | 4.00 (3.97-4.02) | 3.89 (3.88-3.91) | 3.80 (3.77-3.82) | <0.001 |
  TG/HDL-C | 1.64 (1.63-1.66) | 1.57 (1.56-1.58) | 1.5 (1.48-1.5) | 1.42 (1.40-1.43) | <0.001 |
  TC/HDL-C | 4.97 (4.95-5.00) | 4.72 (4.70-4.74) | 4.46 (4.44-4.48) | 4.21 (4.19-4.23) | <0.001 |
  FPG†| 5.09 (5.07-5.11) | 5.22 (5.20-5.24) | 5.34 (5.32-5.36) | 5.48 (5.46-5.50) | 0.014 |
  BMI (kg/m2) | 27.43 (27.35-27.5) | 28.16 (28.08-28.23) | 28.81 (28.74-28.9) | 29.50 (29.43-29.58) | <0.001 |