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Table 1 Thyroxine and triiodothyronine contents in the blood serum of the rats of different thyroid states and age.

From: Effects of thyroxine and 1-methyl, 2-mercaptoimidazol on phosphoinositides synthesis in rat liver

Animals   T4 T3
Adult control   128 ± 3.80 1.21 ± 0.20
Adult MMl-treated   29.5 ± 5.00** 0.83 ± 0.01*
Adult MMl+T4-treated   57.3 ± 7.30*** 1.61 ± 0.10***
Adult T4-treated 1 654 ± 50.0** 5.78 ± 0.20**
  2 675 ± 98.5** 15.9 ± 4.10**
Old control   70.7 ± 11.6 1.37 ± 0.07
Old T4-treated 1 730 ± 15** 5.8 ± 1.5**
  2 537 ± 128** 4.9 ± 0.0**
  1. The T3 and T4 contents in the blood serum were determined by radioimmunoassays kits. The amount of thyroid hormones in serum was represented as nmol per liter. Treatment of the rats by MMl was performed as described in "Materials and Methods". T4 (200 mg/100 g weight) was injected to the MMl-treated rats 48 h prior to killing or normal rats 15 (1) and 60 (2) min prior to killing. Results are mean ± S.E. of 6–8 individual experiments performing in duplicate. In the Tables 1–2 and Figures 1–3 one experiment is equivalent to measurement of the parameters studied in a sample of liver of single animal. * P < 0.05 vs. control, ** P < 0.001 vs. control, *** P < 0.05 vs. MMl-treated rats.