WHO Media Centre. Cardiovascular diseases (CVDs). Updated may 2017. http://www.who.int/cardiovascular_diseases/en/. Accessed 17 May 2018.
Piepoli MF, Hoes AW, Agewall S, Albus C, Brotons C, Catapano AL, et al. 2016 European guidelines on cardiovascular disease prevention in clinical practice: the sixth joint task force of the European Society of Cardiology and Other Societies on cardiovascular disease prevention in clinical practice (constituted by representatives of 10 societies and by invited experts) developed with the special contribution of the European Association for Cardiovascular Prevention & amp; rehabilitation (EACPR). Eur Heart J. 2016;37:2315–81.
Stone NJ, Robinson JG, Lichtestein AH, Bairey Merz CN, Blum CB, Eckel RH, et al. ACC/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults. A report of the American College of Cardiology/American heart association task force on practice guidelines. J Am Coll Cardiol. 2014;63:2889–934.
Needham M, Mastaglia FL. Statin myotoxicity: a review of genetic susceptibility factors. Neuromuscolar Disord. 2014;24:4–15.
Sirtori CR, Mombelli G, Triolo M, Laaksonen R. Clinical response to statins: mechanism (s) of variable activity and adverse effects. Ann Med. 2012;44:419–33.
Engelfriet P, Hoekstra J, Hoogenveen R, Büchner F, Van Rossum C, Verschuren M. Food and vessels: the importance of a healthy diet to prevent cardiovascular disease. Eur J Cardiovasc Prev Rehabil. 2010;17:50–5.
Catalgol B, Batirel S, Taga Y, Ozer NK. Resveratrol: French paradox revisited. Front Pharmacol. 2012;3:141.
Volpe R, Sotis G. Nutraceuticals: definition and epidemiological rationale for their use in clinical practice. High Blood Pressure Cardiovasc Prev. 2015;22:199–201.
Endo A. A gift from nature: the birth of the statins. Nat Med. 2008;14:1050–2.
Yang CW, Mousa SA. The effect of red yeast rice (Monascus Purpureus) in dyslipidemia and others disorders. Complement Ther Med. 2012;20:466–74.
Cicero AF, Derosa G, Parini A, Maffioli P, D’Addato S, Reggi A, et al. Red yeast rice improves lipid pattern, high-sensitivity C-reactive protein and vascular remodelling parameters in moderately hypercholesterolemic italian subjects. Nutr Res. 2013;33:622–8.
Solà R, Valls RM, Puzo J, Calabuig JR, Brea A, Pedret A, et al. Effects of poly-byoactive compounds on lipid profile and body weight in a moderately hypercholesterolemic population with low cardiovascular disease risk: a multicenter randomized trial. PLoS One. 2014;9(8):e101978.
Ruscica M, Gamaraschi M, Mombelli G, Macchi C, Bosisio R, Pazzucconi F, et al. Nutraceutical approach to moderate cardiometabolic risk: results of a randomized, double-blind and crossover study with Armolipid plus. J Clin Lipidol. 2014;8:61–8.
Marazzi G, Cacciotti L, Pelliccia F, Iaia L, Volterrani M, Caminiti G, et al. Long–term effects of nutraceuticals (berberine, red yeast rice, policosanol) in elderly hypercholesterolemic patients. Adv Ther. 2011;28:1105–13.
Gonnelli S, Caffarelli C, Stolakis K, Cuda C, Giordano N, Nuti R. Efficacy and tolerability of a nutraceutical combination (red yeast Rice, policosanols, and Berberine) in patients with low-moderate risk hypercholesterolemia: a double-blind, placebo-controlled study. Curr Ther Res Clin Exp. 2014;77:1–6.
Becker DJ, Gordon RY, Halbert SC, French B, Morris PB, Rader DJ. Red yeast rice for dyslipidemia in statin-intolerant patients: a randomized trial. Ann Intern Med. 2009;150:830–9.
Li Y, Jiang L, Jia Z, Xin W, Yang S, Yang Q, Wang L. A meta-analysis of red yeast rice: an effective and relatively safe alternative approach for dyslipidemia. PLoS One. 2014;9(6):e98611.
Vallance P, Collier J, Moncada S. Nitric oxide synthesised from L-arginine mediates endothelium dependent dilatation in human veins in vivo. Cardiovasc Res. 1989;23:1053–7.
Creager MA, Gallagher SJ, Girerd XJ, Coleman SM, Dzau VJ, Cooke JP. L-arginine improves endothelium-dependent vasodilatation in hypercholesterolemic humans. J Clin Invest. 1992;90:1248–53.
Böger RH, Bode-Böger SM, Frölich JC. The L-arginine-nitric oxide pathway: role in the atherosclerosis and therapeutic implications. Atherosclerosis. 1996;127:1–11.
Bai Y, Sun L, Yang T, Sun K, Chen J, Hui R. Increase in fasting vascular endothelial function after short-term oral L-arginine is effective when baseline flow-mediated dilatation is low: a meta-analysis of randomized controlled trials. Am J Clin Nutr. 2009;89:77–84.
Tousoulis D, Böger RH, Antoniades C, Siasos G, Stefanadi E, Stefanadis C. Mechanisms of disease: L-arginine in coronary atherosclerosis-a clinical perspective. Nat Clin Pract Cardiovasc Med. 2007;4:274–83.
Cooke JP, Tsao PS. Arginine: a new therapy for atherosclerosis? Circulation. 1997;95:311–2.
Berthe MC, Bernard M, Rasmusen C, Darquy S, Cynober L, Couderc R. Arginine or citrulline associated with a statin stimulates nitric oxide production in bovine aortic endothelial cells. Eur J Pharmacol. 2011;670:566–70.
Flowers N, Hartley L, Todkill D, Stranges S, Rees K. Co-enzyme Q10 supplementation for the primary prevention of cardiovascular disease. Cochrane Database Syst Rev. 2014;12:CD 010405.
Duarte TL, Lunec J. Review: when is an antioxidant not a antioxidant? A review of novel actions and reactions of vitamin C. Free Radic Res. 2005;39:671–86.
Aptekmann NP, Cesar TB. Long-term orange juice consumption is associated with low LDL-cholesterol and apolipoprotein B in normal and moderately hypercholesterolemic subjects. Lipids Health Dis. 2013;12:119.
Baigent C, Keech A, Kearney PM, Blackwell L, Buck G, Pollicino C, et al. Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90,056 participants in 14 randomised trials of statins. Lancet. 2005;366:1267–78.
Nguyen T, Karl M, Santini A. Red yeast rice. Foods. 2017;6(3):E19. https://doi.org/10.3390/foods6030019.
Cicero AF, Derosa G, Pisciotta L, Barbagallo C, SISA-PUFACOL Study Group. Testing the short-term efficacy of a lipid-lowering nutraceutical in the setting of clinical practice: a multicenter study. J Med Food. 2015;18:1270–3.
Lu Z, Kou W, Du B, Wu Y, Zhao S, Brusco OA, et al. Effect of Xuezhikang, an extract from red yeast chinese rice, on coronary events in a chinese population with previous myocardial infarction. Am J Cardiol. 2008;101:1689–93.
Lin CC, Li TC, Lai MM. Efficacy and safety of Monascus purpureus went rice in subjects with hyperlipidemia. Eur J Endocrinol. 2005;153:679–86.
Schulze F, Glos S, Petruschka D, Altenburg C, Maas R, Benndorf R, et al. L-arginine enhances the triglyceride-lowering effect of simvastatin in patients with elevated plasma triglycerides. Nutr Res. 2009;29:291–7.
Barrios V, Escobar C, Cicero AF, Burke D, Fasching P, Banach M, Bruckert E. A nutraceutical approach (Armolipid plus) to reduce total and LDL cholesterol in individuals with mild to moderate dyslipidemia: review of the clinical evidence. Atheroscler Suppl. 2017;24:1–15.