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Fig. 5 | Lipids in Health and Disease

Fig. 5

From: Accumulation of LDL/ox-LDL in the necrotic region participates in osteonecrosis of the femoral head: a pathological and in vitro study

Fig. 5

The cellular uptake of LDL and ox-LDL in MLO-Y4 cells in normoxic and hypoxic environments. A The relative expression of LDLR, collectin-12 and SR-B1 in MLO-Y4 cells in normoxic and hypoxic environments. B The relative expression of LDLR and main SRs in MLO-Y4 and RAW264.7 cells. C and D Immunofluorescence and quantitative statistics of LDL internalised by MLO-Y4 cells in normoxic and hypoxic environments. E and F Immunofluorescence and quantitative statistics of ox-LDL internalised by MLO-Y4 cells in normoxic and hypoxic environments. G The relative MDA content in MLO-Y4 cells after incubation with ox-LDL in normoxic and hypoxic environments. Data are represented as the mean ± SD of three independent experiments unless particularly stated, and the percentage of LDL/ox-LDL-positive cells were calculated from five random fields (200×). Comparisons are made using Student’s t test. ***P <0.005; ****P <0.001; scale bar = 100μm

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Lipids in Health and Disease

ISSN: 1476-511X