Fig. 5

CLP treatment improves glucose intolerance in the HFD-fed mice. After fasted for 6 h, individual mice were administrated with D-glucose (2 g/kg body weight) by gavage and their blood glucose levels were measured before as the fasting blood glucose and 30, 60, 90, and 120 min post glucose injection. A The levels of fasting blood glucose. B The dynamic changes in blood glucose levels in individual groups of mice. C The area under curve of OGTT. NC: The control; HFD: The HFD-fed mice receiving vehicle treatment. CLP-50: The HFD-fed mice receiving 50 mg/kg/d CLP; CLP-150: The HFD-fed mice receiving 150 mg/kg/d CLP. Data were analyzed by student’s t test and expressed as the mean ± SEM.^*P < 0.05 vs. the NC group; ^#P < 0.05 vs. the HFD group