Li X, Zeng F, Huang Y, Liu B. The positive effects of heteropolysaccharide on NAFLD and regulation of the gut microbiota. Int J Mol Sci. 2019;20(21):5302.
Article
CAS
Google Scholar
Sheka AC, Adeyi O, Thompson J, Hameed B, Crawford PA, Ikramuddin S. Nonalcoholic steatohepatitis: a review. JAMA. 2020;323:1175–83.
Article
CAS
Google Scholar
Hu H, Lin A, Kong M, Yao X, Yin M, Xia H, Ma J, Liu H. Intestinal microbiome and NAFLD: molecular insights and therapeutic perspectives. J Gastroenterol. 2020;55:142–58.
Article
CAS
Google Scholar
Powell EE, Wong VW-S, Rinella M. Non-alcoholic fatty liver disease. Lancet. 2021;397:2212–24.
Article
CAS
Google Scholar
Xu Y, Guo W, Zhang C, Chen F, Tan HY, Li S, Wang N, Feng Y. Herbal medicine in the treatment of non-alcoholic fatty liver diseases-efficacy, action mechanism, and clinical application. Front Pharmacol. 2020;11:601.
Article
CAS
Google Scholar
Han H, Qiu F, Zhao H, Tang H, Li X, Shi D. Dietary flaxseed oil prevents western-type diet-induced nonalcoholic fatty liver disease in apolipoprotein-e knockout mice. Oxid Med Cell Longev. 2017;2017:3256241.
Article
Google Scholar
Montaigne D, Butruille L, Staels B. PPAR control of metabolism and cardiovascular functions. Nat Rev Cardiol. 2021;18:809–23.
Article
CAS
Google Scholar
Tan H, Song W, Liu S, Song Q, Zhou T, Wang Y, Hou Y. Molecular mechanism of palmitic acid on myocardial contractility in hypertensive rats and its relationship with neural nitric oxide synthase protein in cardiomyocytes. Biomed Res Int. 2021;2021:6657476.
Article
Google Scholar
Puca F, Yu F, Bartolacci C, Pettazzoni P, Carugo A, Huang-Hobbs E, Liu J, Zanca C, Carbone F, Del Poggetto E, et al. Medium-chain Acyl-CoA dehydrogenase protects mitochondria from lipid peroxidation in glioblastoma. Cancer Discov. 2021;11:2904–23.
Article
CAS
Google Scholar
Zheng F, Cai Y. Concurrent exercise improves insulin resistance and nonalcoholic fatty liver disease by upregulating PPAR-γ and genes involved in the beta-oxidation of fatty acids in ApoE-KO mice fed a high-fat diet. Lipids Health Dis. 2019;18:6.
Article
Google Scholar
Li X, Gong H, Yang S, Yang L, Fan Y, Zhou Y. Pectic Bee Pollen Polysaccharide from Rosa rugosa Alleviates Diet-Induced Hepatic Steatosis and Insulin Resistance via Induction of AMPK/mTOR-Mediated Autophagy. Molecules. 2017;22(5):699.
Article
Google Scholar
Choi JW, Synytsya A, Capek P, Bleha R, Pohl R, Park YI. Structural analysis and anti-obesity effect of a pectic polysaccharide isolated from Korean mulberry fruit Oddi (Morus alba L). Carbohydr Polym. 2016;146:187–96.
Article
CAS
Google Scholar
Doucha J, Lívanský K, Kotrbácek V, Zachleder V. Production of Chlorella biomass enriched by selenium and its use in animal nutrition: a review. Appl Microbiol Biotechnol. 2009;83:1001–8.
Article
CAS
Google Scholar
Krienitz L, Huss VAR, Bock C. Chlorella: 125 years of the green survivalist. Trends Plant Sci. 2015;20:67–9.
Article
CAS
Google Scholar
Luo W, Pröschold T, Bock C, Krienitz L. Generic concept in Chlorella-related coccoid green algae (Chlorophyta, Trebouxiophyceae). Plant Biol (Stuttg). 2010;12:545–53.
Article
CAS
Google Scholar
Dodgson KS, Price RG. A note on the determination of the ester sulphate content of sulphated polysaccharides. Biochem J. 1962;84:106–10.
Article
CAS
Google Scholar
Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. Protein measurement with the Folin phenol reagent. J Biol Chem. 1951;193:265–75.
Article
CAS
Google Scholar
Wei YA, Fang JN. [Determination of purity and molecular weight of polysaccharides by high performance gel permeation chromatography]. Yao Xue Xue Bao. 1989;24:532–6.
CAS
Google Scholar
Petersen KF, Dufour S, Li F, Rothman DL, Shulman GI. Ethnic and sex differences in hepatic lipid content and related cardiometabolic parameters in lean individuals. JCI Insight. 2022;7:e157906.
Article
Google Scholar
Miyake T, Matsuura B, Furukawa S, Ishihara T, Yoshida O, Miyazaki M, Watanebe K, Shiomi A, Nakaguchi H, Yamamoto Y, et al. Fatty liver with metabolic disorder, such as metabolic dysfunction-associated fatty liver disease, indicates high risk for developing diabetes mellitus. J Diabetes Investig. 2022;13:1245–52.
Article
CAS
Google Scholar
Li Y, Qin J, Cheng Y, Lv D, Li M, Qi Y, Lan J, Zhao Q, Li Z. Marine sulfated polysaccharides: preventive and therapeutic effects on metabolic syndrome: a review. Mar Drugs. 2021;19:608.
Article
CAS
Google Scholar
Anwar R, Rabail R, Rakha A, Bryla M, Roszko M, Aadil RM, Kieliszek M. Delving the role of : an edible wild plant to mitigate the biomarkers of metabolic syndrome. Oxid Med Cell Longev. 2022;2022:5720372.
Article
Google Scholar
Wang P, Guo P, Wang Y, Teng X, Zhang H, Sun L, Xue M, Liang H. Propolis ameliorates alcohol-induced depressive symptoms in C57BL/6J mice by regulating intestinal mucosal barrier function and inflammatory reaction. Nutrients. 2022;14:1213.
Article
CAS
Google Scholar
Yokota T, Nomura K, Nagashima M, Kamimura N. Fucoidan alleviates high-fat diet-induced dyslipidemia and atherosclerosis in ApoE(shl) mice deficient in apolipoprotein E expression. J Nutr Biochem. 2016;32:46–54.
Article
CAS
Google Scholar
du Preez R, Paul N, Mouatt P, Majzoub ME, Thomas T, Panchal SK, Brown L. Carrageenans from the red seaweed attenuate symptoms of diet-induced metabolic syndrome in rats. Mar Drugs. 2020;18:97.
Article
Google Scholar
Paim RTT, Benjamin SR, Rondina D, Marques MMM, Viana DDA, Gonzaga MLDC, Vieira ÍGP, Mendes FNP, Rodrigues PAS, Guedes MIF. Antihypercholesterolemic effects of fruit aqueous extract of (Miller) H. E. Moore in mice diet-induced hypercholesterolemia. Evid Based Complement Alternat Med. 2017;2017:6376173.
Google Scholar
Wang N, Xu P, Yao W, Zhang J, Liu S, Wang Y, Zhang Y. Structural elucidation and anti-diabetic osteoporotic activity of an arabinogalactan from Phellodendron chinense Schneid. Carbohydr Polym. 2021;271:118438.
Article
CAS
Google Scholar
Oki N, Nonaka S, Ozaki S. The effects of an arabinogalactan-protein from the white-skinned sweet potato (Ipomoea batatas L) on blood glucose in spontaneous diabetic mice. Biosci Biotechnol Biochem. 2011;75:596–8.
Article
CAS
Google Scholar
Shih P-H, Shiue S-J, Chen C-N, Cheng S-W, Lin H-Y, Wu L-W, Wu M-S. Fucoidan and fucoxanthin attenuate hepatic steatosis and inflammation of NAFLD through modulation of leptin/adiponectin axis. Mar Drugs. 2021;19:148.
Article
CAS
Google Scholar
Mahmoudi A, Butler AE, Jamialahmadi T, Sahebkar A. Target deconvolution of fenofibrate in nonalcoholic fatty liver disease using bioinformatics analysis. Biomed Res Int. 2021;2021:3654660.
Article
Google Scholar
Mirza AZ, Althagafi II, Shamshad H. Role of PPAR receptor in different diseases and their ligands: Physiological importance and clinical implications. Eur J Med Chem. 2019;166:502–13.
Article
CAS
Google Scholar
Tanaka N, Aoyama T, Kimura S, Gonzalez FJ. Targeting nuclear receptors for the treatment of fatty liver disease. Pharmacol Ther. 2017;179:142–57.
Article
CAS
Google Scholar
Agrawal R. The first approved agent in the Glitazar’s class: saroglitazar. Curr Drug Targets. 2014;15:151–5.
Article
CAS
Google Scholar
Sosale A, Saboo B, Sosale B. Saroglitazar for the treatment of hypertrig-lyceridemia in patients with type 2 diabetes: current evidence. Diabetes Metab Syndr Obes. 2015;8:189–96.
Article
Google Scholar
Honda A, Kamata S, Satta C, Machida Y, Uchii K, Terasawa K, Nemoto A, Oyama T, Ishii I. Structural basis for anti-non-alcoholic fatty liver disease and diabetic dyslipidemia drug saroglitazar as a PPAR α/γ dual agonist. Biol Pharm Bull. 2021;44:1210–9.
Article
CAS
Google Scholar
Kaul U, Parmar D, Manjunath K, Shah M, Parmar K, Patil KP, Jaiswal A. New dual peroxisome proliferator activated receptor agonist-Saroglitazar in diabetic dyslipidemia and non-alcoholic fatty liver disease: integrated analysis of the real world evidence. Cardiovasc Diabetol. 2019;18:80.
Article
Google Scholar
Cui S, Pan X-J, Ge C-L, Guo Y-T, Zhang P-F, Yan T-T, Zhou J-Y, He Q-X, Cheng L-H, Wang G-J, et al. Silybin alleviates hepatic lipid accumulation in methionine-choline deficient diet-induced nonalcoholic fatty liver disease in mice via peroxisome proliferator-activated receptor α. Chin J Nat Med. 2021;19:401–11.
CAS
Google Scholar