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Fig. 6 | Lipids in Health and Disease

Fig. 6

From: Characterization of a lipid droplet and endoplasmic reticulum stress related gene risk signature to evaluate the clinical and biological value in hepatocellular carcinoma

Fig. 6

Relationship between the risk signature and immune checkpoints and immune cells in the TCGA cohort (Pearson correlation analysis). a Correlation between the risk scores and the expression of PD-L1, CTLA-4, TIM3, LAG-3, PD-1 and PD-L2. b Correlation between the risk scores and the expression of B cell, CD4 + T cell, CD8 + T cell, neutrophil, macrophage and dendritic cells. Correlation between the risk score and the expression of TMB in each patient (c) and low- and high- groups (d). Correlation between the risk score and the expression of MSI-high in each patient (e) and low- and high- groups (f). **** P < 0.001, *** P < 0.01, ** P < 0.05, * P ≥ 0.05. TCGA The Cancer Genome Atlas, PD-L1/2 programmed death ligands 1/2, CTLA-4 cytotoxic T lymphocyte-associated antigen 4, TIM-3 T cell immunoglobulin and mucin-3, LAG-3 lymphocyte-activation gene 3, PD-1 programmed death 1

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Lipids in Health and Disease

ISSN: 1476-511X