Characterization of a lipid droplet and endoplasmic reticulum stress related gene risk signature to evaluate the clinical and biological value in hepatocellular carcinoma

Table 2 The differences in gene expression, Kaplan–Meier survival analysis, and COX analysis of 114 genes in ICGC dataset

Factors	DEGs	Log rank P	Cox P	Factors	DEGs	Log rank P	Cox P	Factors	DEGs	Log rank P	Cox P
ABHD5	*	/	/	FIG4	*	/	/	PLIN2	*	/	/
ACAT1	*	/	/	FITM1	****↓	*	/*	PLIN3	*	/	/
ACSL3	*	/	/	FITM2	*	/	/	PLIN4	*	/	/
ACSL4	****↑	*	*	G0S2	****↓	*	/	PLIN5	*	/	/
AGPAT2	*	/	/	GAPDH	*	/	/	PNPLA2	*	/	/
AIFM2	*	/	/	GBF1	*	/	/	PNPLA3	*	/	/
ANXA2	****↑	***	**	GIMAP2	*	/	/	PNPLA4	*	/	/
APOA4	****↓	*	/	GPAT4	*	/	/	PRPF19	*	/	/
APOB	*	/	/	HILPDA	*	/	/	RAB18	*	/	/
AQP1	*	/	/	HSD17B11	*	/	/	RAB3GAP1	*	/	/
ARAP2	*	/	/	HSD17B13	****↓	***	***	RAB5A	*	/	/
ATG2A	*	/	/	HSD3B7	*	/	/	RAB5C	*	/	/
ATG2B	*	/	/	HSPA5	*	/	/	RAB7A	*	/	/
AUP1	*	/	/	ICE2	*	/	/	RAB8A	*	/	/
BCAP31	****↑	***	***	IRAK1	****↑	****	***	RAP1B	*	/	/
BSCL2	*	/	/	LDAH	*	/	/	RBP1	****↓	*	/
CAV1	*	/	/	LIPE	*	/	/	RSAD2	*	/	/
CAV2	*	/	/	LMLN	*	/	/	SCCPDH	*	/	/
CAVIN1	*	/	/	LPCAT1	*	/	/	SCD	*	/	/
CDKN1A	*	/	/	LPCAT2	*	/	/	SET	*	/	/
CES1	*	/	/	LPIN1	*	/	/	SIGMAR1	*	/	/
CIDEB	****↓	*	/	LSS	*	/	/	SNAP23	*	/	/
CIDEC	*	/	/	MAP4K4	*	/	/	SPAST	*	/	/
CKAP4	****↑	***	****	MBOAT7	*	/	/	SQLE	****↑	***	**
CPT1A	*	/	/	METTL7A	*	/	/	STARD13	*	/	/
CTDNEP1	*	/	/	METTL7B	*	/	/	STX5	*	/	/
CYB5R3	*	/	/	MGLL	*	/	/	SYNGR2	*	/	/
DFFA	*	/	/	MTTP	*	/	/	TMEM135	*	/	/
DGAT1	*	/	/	NAPA	*	/	/	TPD52	*	/	/
DGAT2	*	/	/	NCEH1	*	/	/	TRAF6	*	/	/
DNAAF1	*	/	/	NNMT	****↓	*	/	TSC1	*	/	/
EDA	*	/	/	NSDHL	*	/	/	UBE2G2	*	/	/
EHD1	*	/	/	NSF	*	/	/	VAMP4	*	/	/
FAAH2	*	/	/	OSBPL2	*	/	/	VAPA	*	/	/
FABP1	****↓	*	/	PCYT1A	*	/	/	VCP	*	/	/
FABP4	*	/	/	PEMT	****↓	*	/	VMP1	*	/	/
FAF2	*	/	/	PITPNM1	*	/	/
FASN	*	/	/	PLD1	*	/	/
FGF21	*	/	/	PLIN1	*	/	/

ICGC International Cancer Genome Collaboratory, DEGs Differentially expressed genes
^**** P < 0.001
^*** P = 0.01–0.001
^** P = 0.05–0.01
^* P ≥ 0.05

ISSN: 1476-511X