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Table 2 Comparison of blood FAs by group. Significant differences, VIP > 1 are indicated in bold and reflect potential obesity biomarkers

From: Free fatty acids and peripheral blood mononuclear cells (PBMC) are correlated with chronic inflammation in obesity

Fatty acid

(µg/ml)

Normal weigh(N = 25)

Obesity

(N = 27)

P

VIP

Potential biomarkers

Total-SFA

423.22 ± 75.96

619.78 ± 228.77

< 0.001

1.294

Yes

C6:0

0.00 ± 0.00

0.01 ± 0.00

0.007

0.961

 

C8:0

0.26 ± 0.11

0.49 ± 0.38

0.005

0.985

 

C10:0

0.74 ± 0.39

0.81 ± 0.46

0.562

0.562

 

C11:0

0.00 ± 0.00

0.01 ± 0.00

0.003

0.945

 

C12:0

0.44 ± 0.35

0.60 ± 0.57

0.244

0.669

 

C13:0

0.01 ± 0.00

0.03 ± 0.02

0.002

1.101

Yes

C14:0

4.29 ± 3.09

11.29 ± 12.51

0.009

1.100

Yes

C15:0

1.23 ± 0.48

2.00 ± 0.98

< 0.001

1.180

Yes

C16:0

285.51 ± 53.32

428.24 ± 157.92

< 0.001

1.304

Yes

C17:0

2.26 ± 0.80

3.49 ± 1.60

0.001

1.106

Yes

C18:0

109.16 ± 24.02

151.24 ± 54.64

< 0.001

1.140

Yes

C20:0

0.74 ± 0.32

0.95 ± 0.63

0.143

0.637

 

C21:0

0.12 ± 0.03

0.17 ± 0.07

0.008

0.995

 

C22:0

9.25 ± 3.50

15.61 ± 8.03

< 0.001

1.137

Yes

C23:0

0.05 ± 0.01

0.07 ± 0.03

0.074

0.700

 

C24:0

0.27 ± 0.09

0.34 ± 0.20

0.088

0.619

 

Total-MUFA

283.69 ± 85.00

487.26 ± 227.64

< 0.001

1.268

Yes

C14:1N5

0.13 ± 0.15

0.69 ± 0.79

< 0.001

0.965

 

C15:1N5

0.39 ± 0.28

0.77 ± 0.43

< 0.001

1.145

Yes

C16:1N7

13.37 ± 6.15

36.47 ± 27.30

< 0.001

1.247

Yes

C17:1N7

0.85 ± 0.35

2.00 ± 1.24

< 0.001

1.298

Yes

C18:1TN9

0.32 ± 0.13

0.45 ± 0.21

0.014

0.753

 

C18:1N9

216.34 ± 57.46

393.59 ± 185.98

< 0.001

1.306

Yes

C20:1N9

2.17 ± 0.56

3.35 ± 1.64

0.001

1.020

Yes

C22:1N9

0.98 ± 0.64

1.21 ± 0.94

0.305

0.591

 

C24:1N9

30.44 ± 10.19

45.64 ± 18.03

< 0.001

1.048

Yes

Total-PUFA

643.26 ± 151.60

795.67 ± 254.27

0.012

1.016

Yes

Total-N3

28.88 ± 7.77

40.92 ± 19.09

0.005

1.126

Yes

C18:3N3

9.43 ± 4.61

14.47 ± 6.90

0.003

0.982

 

C20:3N3

0.91 ± 0.27

1.07 ± 0.40

0.104

0.809

 

C20:5N3

0.24 ± 0.07

0.40 ± 0.21

< 0.001

1.167

Yes

C22:5N3

8.45 ± 2.22

12.34 ± 4.82

< 0.001

1.122

Yes

C22:6N3

8.40 ± 2.65

11.12 ± 4.04

0.006

1.046

Yes

Total-N6

614.37 ± 146.87

754.75 ± 237.08

0.014

0.997

 

C18:2TTN6

0.06 ± 0.03

0.11 ± 0.09

0.022

0.676

 

C18:2N6

392.81 ± 86.37

517.29 ± 178.12

0.003

1.098

Yes

C18:3N6

10.08 ± 11.95

5.42 ± 2.76

0.055

0.554

 

C20:2N6

5.04 ± 1.41

6.60 ± 2.66

0.012

1.034

Yes

C20:3N6

22.95 ± 11.17

32.75 ± 15.90

0.014

0.921

 

C20:4N6

137.72 ± 42.51

179.85 ± 57.52

0.004

0.894

 

C22:2N6

0.18 ± 0.07

0.23 ± 0.20

0.179

0.597

 

C22:4N6

4.90 ± 1.13

6.57 ± 2.40

0.003

1.028

Yes

C22:5N6

4.83 ± 1.23

5.89 ± 2.02

0.029

0.775

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