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Table 1 Comparison of subject baseline characteristics according to MASLD

From: Increased visceral fat area to skeletal muscle mass ratio is positively associated with the risk of metabolic dysfunction-associated steatotic liver disease in a Chinese population

 

All subjects

(n = 10,916)

Non-MASLD group

(n = 6774)

MASLD group

(n = 4142)

P

Age (years)

49.65±11.00

48.72±11.32

51.17±10.28

< 0.001

Male (%)

6150 (56.34)

3006 (44.38)

3144 (75.91)

< 0.001

Current smoking (%)

2296 (21.03)

1061 (15.66)

1235 (29.82)

< 0.001

Current drinking (%)

4142 (37.97)

1847 (29.59)

2295 (49.10)

< 0.001

Exercise (%)

2370(21.71)

1635(24.14)

735(17.35)

< 0.001

Hypertension history (%)

2028 (18.58)

814 (12.02)

1214 (29.31)

< 0.001

Diabetes history (%)

627 (5.74)

217 (3.20)

410 (9.90)

< 0.001

BMI (kg/m2)

23.96±3.17

23.04±2.85

25.45±3.10

< 0.001

WC (cm)

82.65±4.89

78.46±8.56

89.48±7.77

< 0.001

PBF (%)

27.99±5.75

27.51±5.88

28.77±5.45

< 0.001

VFA (cm2)

83.73±27.73

77.89±25.69

93.29±28.27

< 0.001

SMI (%)

39.67±3.61

39.74±3.73

39.56±3.40

< 0.05

VSR (cm2/kg)

3.03 (2.45, 3.94)

2.96 (2.38, 3.93)

3.10 (2.58, 3.95)

< 0.001

SBP (mmHg)

122.86±17.21

119.57±17.09

128.23±16.02

< 0.001

DBP (mmHg)

73.46±11.39

70.89±10.87

77.67±10.96

< 0.001

TC (mmol/L)

4.89±0.93

4.84±0.91

4.98±0.96

< 0.001

TG (mmol/L)

1.30 (0.91, 1.95)

1.06 (0.79, 1.48)

1.86 (1.35, 2.64)

< 0.001

HDL-C (mmol/L)

1.31±0.36

1.42±0.37

1.12±0.26

< 0.001

LDL-C (mmol/L)

2.74±0.74

2.71±0.73

2.79±0.77

< 0.001

Hcy (µmol/L)

9.50 (8.00, 11.30)

9.00 (7.50, 10.90)

10.20 (8.80, 11.90)

< 0.001

ALT (U/L)

18.00 (13.00, 27.00)

15.00 (12.00, 21.00)

25.00 (18.00, 37.00)

< 0.001

AST (U/L)

19.00 (16.00, 23.00)

18.00 (15.00, 21.00)

21.00 (17.00, 26.00)

< 0.001

\(\gamma -\)GGT (U/L)

22.00 (14.00, 38.00)

17.00 (12.00, 26.00)

34.00 (23.00, 56.00)

< 0.001

FPG (mmol/L)

4.79 (4.44, 5.21)

4.69 (4.37, 5.02)

5.02 (4.60, 5.61)

< 0.001

HbA1c (%)

5.60 (5.40, 5.90)

5.60 (5.30, 5.80)

5.80 (5.50, 6.20)

< 0.001

HOMA-IR

1.38 (0.95, 2.02)

1.12 (0.82, 1.22)

1.96 (1.43, 2.74)

< 0.001

SUA (µmol/L)

331.05±86.84

304.77±78.76

374.03±82.18

< 0.001

25(OH)D (nmol/L)

54.56±20.93

54.30±21.85

54.98±19.32

0.100

  1. Abbreviations ALT, alanine aminotransferase; AST, aspartate aminotransferase; BMI, body mass index; DBP, diastolic blood pressure; FPG, fasting plasma glucose; \(\gamma -\)GGT:γ-glutamyl transferase; HbA1c, glycated hemoglobin; HDL-C, high-density lipoprotein cholesterol; Hcy, homocysteine; LDL-C, low-density lipoprotein cholesterol; MASLD: metabolic dysfunction-associated steatotic liver disease; PBF, percent body fat; SBP, systolic blood pressure; SMI, skeletal muscle mass index; SUA, serum uric acid; TC, total cholesterol; TG, triglyceride; VFA, visceral fat area; VSR, visceral fat area to skeletal muscle mass ratio; WC, waist circumference
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Lipids in Health and Disease

ISSN: 1476-511X