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  1. Increased evidence has reported the association of genetic polymorphisms of Apolipoprotein E (APOE) with serum lipids. However, few studies have explored the combined effects of APOE, gender, and age.

    Authors: Xiaofeng Liu, Qingwen Lin, Kengna Fan, Minjie Tang, Weiqing Zhang, Bin Yang and Qishui Ou
    Citation: Lipids in Health and Disease 2021 20:158
    Content type: Research Published on:

  2. To determine the effect of genetic polymorphism of drug transporters on the efficacy of treatment with Rosuvastatin, Atorvastatin and Simvastatin in patients with hyperlipidemia.

    Authors: Andrey Sivkov, Natalya Chernus, Roman Gorenkov, Sergey Sivkov, Svetlana Sivkova and Tamara Savina
    Citation: Lipids in Health and Disease 2021 20:157
    Content type: Research Published on:

  3. Rash, photosensitivity, erythema multiforme, and the acute generalized exanthematous pustulosis (AGEP) are relatively uncommon adverse reactions of drugs. To date, the etiology is not well understood and indiv...

    Authors: Markus Blaess, Lars Kaiser, Oliver Sommerfeld, René Csuk and Hans-Peter Deigner
    Citation: Lipids in Health and Disease 2021 20:156
    Content type: Hypothesis Published on:

  4. Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by impairments in social interaction and restricted and repetitive behaviors. Neuroinflammation and abnormal lipid mediators have b...

    Authors: Afaf El-Ansary, Manan Alhakbany, Abeer Aldbass, Hanan Qasem, Sarah Al-Mazidi, Ramesa Shafi Bhat and Laila Al-Ayadhi
    Citation: Lipids in Health and Disease 2021 20:155
    Content type: Research Published on:

    The Correction to this article has been published in Lipids in Health and Disease 2021 20:172

  5. We investigated the role of ANGPTL3 and ANGPTL4 in atherosclerosis development and determined whether plasma concentrations of ANGPTL3 and ANGPTL4 are related to the degree of coronary stenosis.

    Authors: Ting Sun, Wanlin Zhan, Lijiang Wei, Zuojun Xu, Li Fan, Yang Zhuo, Changqian Wang and Junfeng Zhang
    Citation: Lipids in Health and Disease 2021 20:154
    Content type: Research Published on:

  6. Despite recent advances in recognizing more reliable indicators to estimate the coronary artery disease (CAD) patients’ response to treatment and prognosis, less attention has been paid to evaluating them in c...

    Authors: Marjan Mahdavi-Roshan, Arsalan Salari, Azin Vakilpour, Amir Savar Rakhsh and Zeinab Ghorbani
    Citation: Lipids in Health and Disease 2021 20:153
    Content type: Research Published on:

  7. The prevalence of precocious puberty is increasing. Obesity has been demonstrated to be associated with changes in the adipokine profile and incidence of early puberty in girls. This study assessed the puberta...

    Authors: Elnaz Shokri, Ali Heidarianpour and Zahra Razavi
    Citation: Lipids in Health and Disease 2021 20:152
    Content type: Research Published on:

  8. Acylcarnitine is an intermediate product of fatty acid oxidation. It is reported to be closely associated with the occurrence of diabetic cardiomyopathy (DCM). However, the mechanism of acylcarnitine affecting...

    Authors: Dan-meng Zheng, Zhen-ni An, Ming-hao Ge, Dong-zhuo Wei, Ding-wen Jiang, Xue-jiao Xing, Xiao-lei Shen and Chang Liu
    Citation: Lipids in Health and Disease 2021 20:151
    Content type: Research Published on:

  10. Extremely low levels of high-density lipoprotein cholesterol (HDL-C) are related to high cardiovascular mortality. The underlying mechanism is not well known. This research aims to study the clinical character...

    Authors: Lufan Sun, Lian Duan and Dalin Jia
    Citation: Lipids in Health and Disease 2021 20:149
    Content type: Research Published on:

  11. The prevalence of dyslipidemia in China is increasing annually. Current studies suggest that dyslipidemia affects the antiviral efficacy of hepatitis C virus (HCV) therapies, while recent studies suggest that ...

    Authors: Ziqiang Xia, Juzeng Zheng, Liang Zheng, Endian Zheng, Zhuolin Zou, Xiong Sheng and Jinming Wu
    Citation: Lipids in Health and Disease 2021 20:148
    Content type: Research Published on:

  12. Lipid levels in blood have decreased considerably during the past decades in the general population partly due to use of statins. This study aims to investigate the trends in lipid levels between 2001 and 2018...

    Authors: Anna E. Engell, Henrik L. Jørgensen, Bent S. Lind, Anton Pottegård, Christen L. Andersen, John S. Andersen, Margit Kriegbaum, Mia K. Grand and Lise Bathum
    Citation: Lipids in Health and Disease 2021 20:147
    Content type: Research Published on:

  13. Bladder cancer (BLCA) is a common cancer associated with an unfavorable prognosis. Increasing numbers of studies have demonstrated that lipid metabolism affects the progression and treatment of tumors. Therefo...

    Authors: Ke Zhu, Liu Xiaoqiang, Wen Deng, Gongxian Wang and Bin Fu
    Citation: Lipids in Health and Disease 2021 20:146
    Content type: Research Published on:

  14. Non-alcoholic fatty liver disease (NAFLD) has been entitled as metabolic-dysfunction associated fatty liver disease (MAFLD). Therefore anthropometric indicators of adiposity may provide a non-invasive predicti...

    Authors: Jinwei Cai, Cuiting Lin, Shuiqing Lai, Yingshan Liu, Min Liang, Yingfen Qin, Xinghuan Liang, Aihua Tan, Yong Gao, Zheng Lu, Chunlei Wu, Shengzhu Huang, Xiaobo Yang, Haiying Zhang, Jian Kuang and Zengnan Mo
    Citation: Lipids in Health and Disease 2021 20:145
    Content type: Research Published on:

  15. Evidence on the relationship between the low−/high-density lipoprotein cholesterol ratio (LDL-C/HDL-C) and carotid plaques remains limited. This study aimed to examine the association between LDL-C/HDL-C and c...

    Authors: Zhu Li, Qi Cheng, Yijia Liu, Xufeng Cheng, Shuo Wang, Yuanyuan He, Xu Wang, Mengnan Huang, Yue Li, Xiaoxue Xue, Yilan Xu, Lin Li, Yanchao Zheng, Rongrong Yang, Shan Gao and Chunquan Yu
    Citation: Lipids in Health and Disease 2021 20:144
    Content type: Research Published on:

  16. Breast cancer is one of the main leading causes of women death. In recent years, attention has been focused on the role of lipoproteins, alterations of cholesterol metabolism and oxidative stress in the molecu...

    Authors: Gabriele Mazzuferi, Tiziana Bacchetti, Md Obaidul Islam and Gianna Ferretti
    Citation: Lipids in Health and Disease 2021 20:143
    Content type: Review Published on:

  17. Effective and applicable predictors of non-alcoholic fatty liver disease (NAFLD) are needed for the non-obese Chinese population. This study was undertaken to investigate: whether serum gamma-glutamyl transfer...

    Authors: Liling Wu, Man Zhang, Haofei Hu and Qijun Wan
    Citation: Lipids in Health and Disease 2021 20:142
    Content type: Research Published on:

  18. The global coronavirus disease 2019 (COVID-19) pandemic caused by the SARS-CoV-2 coronavirus started in March 2020. The conclusions from numerous studies indicate that people with comorbidities, such as arteri...

    Authors: Stanisław Surma, Maciej Banach and Joanna Lewek
    Citation: Lipids in Health and Disease 2021 20:141
    Content type: Review Published on:

  19. Recent studies have substantiated the role of the triglyceride glucose (TyG) index in predicting the prognosis of coronary artery disease (CAD) patients, while no relevant studies have revealed the association...

    Authors: Ang Gao, Jinxing Liu, Chengping Hu, Yan Liu, Yong Zhu, Hongya Han, Yujie Zhou and Yingxin Zhao
    Citation: Lipids in Health and Disease 2021 20:140
    Content type: Research Published on:

  20. Remnant cholesterol (RC) mediates the progression of coronary artery disease, diabetic complications, hypertension, and chronic kidney disease. Limited information is available on the association of RC with no...

    Authors: Yang Zou, Jianyun Lan, Yanjia Zhong, Shuo Yang, Huimin Zhang and Guobo Xie
    Citation: Lipids in Health and Disease 2021 20:139
    Content type: Research Published on:

  22. Lipid management is the first line of treatment for decreasing the incidence of cardiovascular events in patients with coronary heart disease (CHD), and a variety of indicators are used to evaluate lipid manag...

    Authors: Jiacheng Lai, Yongsheng Han, Chongjian Huang, Bin Li, Jingshu Ni, Meili Dong, Yikun Wang and Qingtong Wang
    Citation: Lipids in Health and Disease 2021 20:137
    Content type: Research Published on:

  23. Nonalcoholic fatty liver disease (NAFLD) is a leading cause of chronic liver disease and cirrhosis. NAFLD is mediated by changes in lipid metabolism and known risk factors include obesity, metabolic syndrome, ...

    Authors: Yvonne N. Flores, Aryana T. Amoon, Baolong Su, Rafael Velazquez-Cruz, Paula Ramírez-Palacios, Jorge Salmerón, Berenice Rivera-Paredez, Janet S. Sinsheimer, Aldons J. Lusis, Adriana Huertas-Vazquez, Sammy Saab, Beth A. Glenn, Folasade P. May, Kevin J. Williams, Roshan Bastani and Steven J. Bensinger
    Citation: Lipids in Health and Disease 2021 20:136
    Content type: Research Published on:

  24. Dysregulated lipid metabolism is critically involved in the development of hepatocellular carcinoma (HCC). The respective metabolic pathways affected in HCC can be identified using suitable experimental models...

    Authors: Elisabeth M. Haberl, Rebekka Pohl, Lisa Rein-Fischboeck, Marcus Höring, Sabrina Krautbauer, Gerhard Liebisch and Christa Buechler
    Citation: Lipids in Health and Disease 2021 20:135
    Content type: Research Published on:

  25. Conicity index, body-shape index, lipid accumulation product (LAP), waist circumference (WC), triglyceride, triglyceride-glucose (TyG) index, hepatic steatosis index (HSI), waist-to-height ratio (WHtR), TyG in...

    Authors: Guotai Sheng, Song Lu, Qiyang Xie, Nan Peng, Maobin Kuang and Yang Zou
    Citation: Lipids in Health and Disease 2021 20:134
    Content type: Research Published on:

  26. Blood lipids are essential components for cellular growth. An inverse association between serum lipid levels and risk of cancer has led to a controversy among previous studies. The aim of this prospective coho...

    Authors: Yu-Chen Chang, Chien-Ju Lin, Tzu-Lin Yeh, Ming-Chieh Tsai, Le-Yin Hsu, Kuo-Liong Chien and Hsin-Yin Hsu
    Citation: Lipids in Health and Disease 2021 20:133
    Content type: Research Published on:

  27. The relationship between nonalcoholic fatty liver disease (NAFLD) and obesity-related indices has been analyzed separately thus far, and evidence comparing these indices together is still lacking, especially i...

    Authors: Fangfei Xie, Yuyu Pei, Quan Zhou, Deli Cao and Yun Wang
    Citation: Lipids in Health and Disease 2021 20:132
    Content type: Research Published on:

  28. Limited studies regarding the correlation of lipid accumulation product (LAP) with a decreased estimated glomerular filtration rate (eGFR) have yielded conflicting findings, and no report has demonstrated the ...

    Authors: Pijun Yan, Yong Xu, Ying Miao, Qian Tang, Yuru Wu, Xue Bai, Zhihong Zhang, Qian Li and Qin Wan
    Citation: Lipids in Health and Disease 2021 20:131
    Content type: Research Published on:

  29. High serum Lipoprotein(a) (Lp(a)) level and Apolipoprotein B/Apolipoprotein AΙ (ApoB/ApoA-Ι) ratio are risk factors for cardiovascular disease and kidney disease and have been found to be correlated with the p...

    Authors: Jun Tao, Wen Dai, Chenglin Ye, Qian Yao, Man Zhou and Yan Li
    Citation: Lipids in Health and Disease 2021 20:130
    Content type: Research Published on:

  30. Mycobacterium tuberculosis (Mtb), the main etiology of tuberculosis (TB), is predominantly an intracellular pathogen that has caused infection, disease and death in humans for centuries. Lipid droplets (LDs) are ...

    Authors: Daniel Mekonnen, Awoke Derbie, Adane Mihret, Solomon Abebe Yimer, Tone Tønjum, Baye Gelaw, Endalkachew Nibret, Abaineh Munshae, Simon J. Waddell and Abraham Aseffa
    Citation: Lipids in Health and Disease 2021 20:129
    Content type: Review Published on:

  31. Evidence suggests that proteins related to lipid metabolism, such as apolipoproteins, play an important role in the maintenance of normal vision. While several members of the apolipoprotein family are abundant...

    Authors: Parth A. Patel, Tae Jin Lee, Sai Karthik Kodeboyina, Garrett Jones, Kathryn Bollinger, Lane Ulrich, David Bogorad, Amy Estes, Wenbo Zhi, Shruti Sharma and Ashok Sharma
    Citation: Lipids in Health and Disease 2021 20:128
    Content type: Research Published on:

  32. Coronary artery disease (CAD) is a common cardiovascular disease, and abnormal blood lipid metabolism is an important risk factor. Transforming growth factor-ß (TGF-ß) and its receptor (TGF-ßR) can inhibit the...

    Authors: Haibin Chen, Yiping Wang, Bing Sun, Xunxia Bao, Yu Tang, Feifei Huang, Sibo Zhu and Jiahong Xu
    Citation: Lipids in Health and Disease 2021 20:127
    Content type: Research Published on:

  33. The coronavirus disease 2019 (COVID-19) is caused by the severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2). At present, the COVID-19 has been prevalent worldwide for more than a year and caused...

    Authors: Yanlan Xu, Xinyu Yang, Hua Bian and Mingfeng Xia
    Citation: Lipids in Health and Disease 2021 20:126
    Content type: Review Published on:

  34. Abnormalities in serum lipids and lipoproteins have been documented to link to the risk of cancers in recent years, but its prognostic value for cancer is not known. This study retrospectively evaluated the si...

    Authors: Cong Ma, Xiaoyan Wang, Jingjing Guo and Ping Liu
    Citation: Lipids in Health and Disease 2021 20:69
    Content type: Research Published on:

  35. Research on dyslipidemia during pregnancy in women with gestational diabetes mellitus (GDM) has rarely been conducted in Asia. The present study aimed to evaluate maternal mid-trimester lipid profile in relati...

    Authors: Yuan Li, Xiaoqian Wang, Fengjuan Jiang, Wenqing Chen, Jie Li and Xiaotian Chen
    Citation: Lipids in Health and Disease 2021 20:125
    Content type: Research Published on:

  36. Large observational studies have shown that small, dense LDL subfractions are related to atherosclerotic cardiovascular disease. This study assessed the effects of two highly effective lipid-lowering therapies...

    Authors: Leticia C. S. Pinto, Ana P. Q. Mello, Maria C. O. Izar, Nagila R. T. Damasceno, Antonio M. F. Neto, Carolina N. França, Adriano Caixeta, Henrique T. Bianco, Rui M. S. Póvoa, Flavio T. Moreira, Amanda S. F. Bacchin and Francisco A. Fonseca
    Citation: Lipids in Health and Disease 2021 20:124
    Content type: Research Published on:

  37. The relationship between the APOE gene polymorphism and lipid profiles and atrial fibrillation (AF) remains controversial. The current study purposed to investigate how the APOE gene SNPs (rs429358 and rs7412) an...

    Authors: Xunwei Deng, Jingyuan Hou, Qiaoting Deng and Zhixiong Zhong
    Citation: Lipids in Health and Disease 2021 20:123
    Content type: Research Published on:

  38. Idiopathic membranous nephropathy (IMN) may have various clinical outcomes. Hyperlipidemia is quite common in IMN. However, the utility of the lipid profile in predicting outcomes remains unknown. This study a...

    Authors: Lei Dong, Wang Wei, Min Han and Gang Xu
    Citation: Lipids in Health and Disease 2021 20:122
    Content type: Research Published on:

  39. Current studies support lipid ratios [the total cholesterol (TC)/high-density lipoprotein cholesterol (HDL-C) ratio; the triglyceride (TG)/HDL-C ratio; the low-density lipoprotein cholesterol (LDL -C)/HDL-C ra...

    Authors: Yu Yu, Tian Lan, Dandan Wang, Wangsheng Fang, Yu Tao, Minghui Li, Xiao Huang, Wei Zhou, Tao Wang, Lingjuan Zhu, Huihui Bao and Xiaoshu Cheng
    Citation: Lipids in Health and Disease 2021 20:121
    Content type: Research Published on:

  40. Life expectancy has greatly increased, generating an improvement in screening programs for disease prevention, lifesaving drugs and medical devices. The impact of lowering low-density lipoprotein cholesterol (...

    Authors: Yehudit Eden Friedman, David M. Steinberg, Michal Canetti, Ido Cohen, Shlomo Segev and Ophira Salomon
    Citation: Lipids in Health and Disease 2021 20:120
    Content type: Research Published on:

  41. Blood lipid increases during gestation are considered a physiological adaption, and decrease after delivery. However, some adverse pregnancy outcomes are thought to be related to gestational lipid levels. Ther...

    Authors: Yandi Zhu, Haiyan Zhu, Qinyu Dang, Qian Yang, Dongxu Huang, Yadi Zhang, Xiaxia Cai and Huanling Yu
    Citation: Lipids in Health and Disease 2021 20:119
    Content type: Research Published on:

  42. The present study was aimed to establish a prediction model for in-stent restenosis (ISR) in subjects who had undergone percutaneous coronary intervention (PCI) with drug-eluting stents (DESs).

    Authors: Min-Tao Gai, Bing Zhu, Xiao-Cui Chen, Fen Liu, Xiang Xie, Xiao-Ming Gao, Xiang Ma, Zhen-Yan Fu, Yi-Tong Ma and Bang-dang Chen
    Citation: Lipids in Health and Disease 2021 20:118
    Content type: Research Published on:

  43. Angiopoietin-like proteins (ANGPTL), primarily 3, 4, and 8, play a major role in maintaining energy homeostasis by regulating triglyceride metabolism. This study evaluated the level of ANGPTL3, 4, and 8 in the...

    Authors: Hossein Arefanian, Irina Al-Khairi, Nermeen Abu Khalaf, Preethi Cherian, Sina Kavalakatt, Dhanya Madhu, Aditi Mathur, Mohamed G. Qaddoumi, Fahd Al-Mulla, Jehad Abubaker and Mohamed Abu-Farha
    Citation: Lipids in Health and Disease 2021 20:117
    Content type: Research Published on:

  44. Dyslipidemia is a predisposing factor for coronary heart disease (CHD). High-intensity statin therapy is recommended as secondary prevention. ABCB1 and SLCO1B1 genes influence the efficacy and safety of statin...

    Authors: Tingting Wang, Li Sun, Li Xu, Ting Zhao, Jie Feng, Luhai Yu, Jianhua Wu and Hongjian Li
    Citation: Lipids in Health and Disease 2021 20:116
    Content type: Research Published on:

  45. Cancer-associated cachexia (CAC) is a metabolic syndrome characterized by progressive depletion of adipose and muscle tissue that cannot be corrected by conventional nutritional therapy. Adipose tissue, an imp...

    Authors: Diya Sun, Zuoyou Ding, Lei Shen, Fan Yang, Jun Han and Guohao Wu
    Citation: Lipids in Health and Disease 2021 20:115
    Content type: Research Published on:

  46. Previous epidemiological studies have indicated the seasonal variability of serum lipid levels. However, little research has explicitly examined the separate secular and seasonal trends of dyslipidemia. The pr...

    Authors: Jiahui Lao, Yafei Liu, Yang Yang, Peng Peng, Feifei Ma, Shuang Ji, Yujiao Chen and Fang Tang
    Citation: Lipids in Health and Disease 2021 20:114
    Content type: Research Published on:

  47. Hypertriglyceridemia has emerged as a critical coronary artery disease (CAD) risk factor. Rare loss-of-function (LoF) variants in apolipoprotein C-III have been reported to reduce triglycerides (TG) and are ca...

    Authors: Shiwali Goyal, Yosuke Tanigawa, Weihua Zhang, Jin-Fang Chai, Marcio Almeida, Xueling Sim, Megan Lerner, Juliane Chainakul, Jonathan Garcia Ramiu, Chanel Seraphin, Blair Apple, April Vaughan, James Muniu, Juan Peralta, Donna M. Lehman, Sarju Ralhan…
    Citation: Lipids in Health and Disease 2021 20:113
    Content type: Research Published on:

  48. Increased physical activity is inversely related to the risk to develop cardiovascular disease (CVD). In a recent systematic review, it was reported that CVD patients had an increased cholesterol absorption an...

    Authors: S. Mashnafi, J. Plat, R. P. Mensink, P. J. Joris, J. P. D. Kleinloog and S. Baumgartner
    Citation: Lipids in Health and Disease 2021 20:112
    Content type: Research Published on:

  49. Limited data are available for validation of low-density lipoprotein cholesterol (LDL) calculation (LDLcal) in the adult Korean population. The aim of this study was to develop and validate a new equation for LDL

    Authors: Rihwa Choi, Mi-Jung Park, Youngju Oh, Sung Ho Kim, Sang Gon Lee and Eun Hee Lee
    Citation: Lipids in Health and Disease 2021 20:111
    Content type: Research Published on:

  50. The current study was conducted to explore the effects of chemerin and homocysteine (Hcy) levels and their associations with the occurrence and development of ischemic cerebrovascular disease (ICVD).

    Authors: Lixuan Wang, Jianpu Jia, Zhen Hong, Leguo Zhang and Junling Zhang
    Citation: Lipids in Health and Disease 2021 20:108
    Content type: Research Published on:
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Lipids in Health and Disease

ISSN: 1476-511X