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  1. Lipid accumulation in the liver and pancreas is primarily caused by combined hyperlipidemia. However, the effect of isolated hypercholesterolemia without hypertriglyceridemia is not fully described. Therefore,...

    Authors: Csaba Csonka, Tamás Baranyai, László Tiszlavicz, Hedvig Fébel, Gergő Szűcs, Zoltán V. Varga, Márta Sárközy, László G. Puskás, Otilia Antal, Andrea Siska, Imre Földesi, Péter Ferdinandy, László Czakó and Tamás Csont
    Citation: Lipids in Health and Disease 2017 16:144
    Content type: Research Published on:

  2. This study used a short-term de-training model to mimic the physiological weight changes during the early retirement stage in Taekwondo (TKD) athletes. This study investigates whether the negative changes in b...

    Authors: Yu-Chi Sung, Yi-Hung Liao, Chung-Yu Chen, Yu-Liang Chen and Chun-Chung Chou
    Citation: Lipids in Health and Disease 2017 16:143
    Content type: Research Published on:

  3. Uric acid (UA) has been suggested as a novel risk factor for diabetes. However, its definite role in this prevalent disease is still the subject of much discussion because it is always accompanied with other m...

    Authors: Neda Seyed-Sadjadi, Jade Berg, Ayse A. Bilgin and Ross Grant
    Citation: Lipids in Health and Disease 2017 16:142
    Content type: Research Published on:

  4. Efficacy-safety of proprotein convertase subtilisin-kexin type 9 (PCSK9) inhibitors, alirocumab (ALI) and evolocumab (EVO), have previously been evaluated through controlled clinical trials with selective pati...

    Authors: Joshua Choi, Amir M Khan, Michael Jarmin, Naila Goldenberg, Charles J Glueck and Ping Wang
    Citation: Lipids in Health and Disease 2017 16:141
    Content type: Research Published on:

  5. Lysophosphatidic acid (LPA) is a bioactive lipid with a wide biological activity. Previous studies have shown its potential usefulness as a diagnostic marker for ovarian cancer. The aim of the study was to inv...

    Authors: Anna Michalczyk, Marta Budkowska, Barbara Dołęgowska, Dariusz Chlubek and Krzysztof Safranow
    Citation: Lipids in Health and Disease 2017 16:140
    Content type: Research Published on:

  6. Recent studies have shown osteocalcin (OC) plays an important role in regulating glucose and lipid metabolism. Thus, the aim of this study was to investigate the association of OC with glucose and lipid metabo...

    Authors: Yuan Chen, Qiang Zhao, Guoli Du and Yancheng Xu
    Citation: Lipids in Health and Disease 2017 16:139
    Content type: Research Published on:

  7. Genotyping of the FAD2.1 and FAD2.3 polymorphisms in the fatty acid desaturase 2 gene (FADS2) shows that they are associated with the fatty acids composition of olive oil samples. However, these associations requ...

    Authors: Rayda Ben Ayed, Karim Ennouri, Hajer Ben Hlima, Slim Smaoui, Mohsen Hanana, Rim Mzid, Sezai Ercişli and Ahmed Rebai
    Citation: Lipids in Health and Disease 2017 16:138
    Content type: Research Published on:

  8. A great number of studies reported that 12/15-lipoxygenase (12/15-LO) played an important role in atherosclerosis. And its arachidonic acid(AA) metabolite, 15(S)-hydroperoxy-5,8,11,13-(Z,Z,Z,E)-eicosatetraenoi...

    Authors: Guohua Ma, Bing Pan, Sufen Ren, Caixia Guo, Yansong Guo, Lixin Wei, Lemin Zheng and Buxing Chen
    Citation: Lipids in Health and Disease 2017 16:137
    Content type: Research Published on:

  9. α-linolenic acid (ALA) is an n-3 polyunsaturated fatty acid (PUFA) and the substrate for long-chain n-3 PUFAs. The beneficial effects of ALA on chronic diseases are still in dispute, unlike those of eicosapent...

    Authors: Jingjing Li, Zhennan Gu, Yong Pan, Shunhe Wang, Haiqin Chen, Hao Zhang, Wei Chen and Yong Q. Chen
    Citation: Lipids in Health and Disease 2017 16:136
    Content type: Research Published on:

  10. The clock genes are involved in regulating cardiovascular functions, and their expression disorders would lead to circadian rhythm disruptions of clock-controlled genes (CCGs), resulting in atherosclerotic pla...

    Authors: Changpo Lin, Xiao Tang, Lirong Xu, Ruizhe Qian, Zhenyu Shi, Lixin Wang, Tingting Cai, Dong Yan, Weiguo Fu and Daqiao Guo
    Citation: Lipids in Health and Disease 2017 16:135
    Content type: Research Published on:

  11. Atherosclerosis is the most common disease of large and medium-sized arteries linked to oxidative stress, dyslipidemia as well as chronic inflammation. The aim of this study was to evaluate the potential healt...

    Authors: Muhammad Ibrahim, Idris Adewale Ahmed, Maryam Abimbola Mikail, Afeez Adekunle Ishola, Samsul Draman, Muhammad Lokman Md Isa and Afzan Mat Yusof
    Citation: Lipids in Health and Disease 2017 16:134
    Content type: Research Published on:

  13. Dyslipidemia is the risk of cardiovascular disease, and their relationship is clear. Lowering serum cholesterol can reduce the risk of coronary heart disease. At present, the main treatment is taking medicine,...

    Authors: Yating Wang and Danyan Xu
    Citation: Lipids in Health and Disease 2017 16:132
    Content type: Review Published on:

  15. Current international guidelines on dyslipidemia are not concordant on various aspects of management. Also, there are no uniformly accepted Indian guidelines. We, therefore, performed a physician survey to und...

    Authors: Gurpreet S. Wander, Uday M. Jadhav, Amruta Chemburkar, Meena Lopez and Jaideep Gogtay
    Citation: Lipids in Health and Disease 2017 16:130
    Content type: Research Published on:

  16. Nonalcoholic fatty liver disease (NAFLD) is highly prevalent worldwide. Experimental studies have shown that cholecystectomy (XGB) increases hepatic fat content in mice and appears associated to NAFLD in large...

    Authors: Víctor Cortés, Nicolás Quezada, Sergio Uribe, Marco Arrese and Flavio Nervi
    Citation: Lipids in Health and Disease 2017 16:129
    Content type: Research Published on:

  17. Lipids are essential building blocks synthesized by complex molecular pathways and deposited as lipid droplets (LDs) in cells. LDs are evolutionary conserved organelles found in almost all organisms, from bact...

    Authors: Gizem Onal, Ozlem Kutlu, Devrim Gozuacik and Serap Dokmeci Emre
    Citation: Lipids in Health and Disease 2017 16:128
    Content type: Review Published on:

  18. BUD13 homolog (BUD13), one of submits of the retention and splicing complex, was identified in yeast as a splicing factor that affected nuclear pre-mRNA retention. While more and more studies demonstrated that...

    Authors: Lili Zhang, Yueyue You, Yanhua Wu, Yangyu Zhang, Mohan Wang, Yan Song, Xinyu Liu and Changgui Kou
    Citation: Lipids in Health and Disease 2017 16:127
    Content type: Short report Published on:

  19. Advanced glycation end products (AGEs) are pathogenic factors of diabetic nephropathy (DN), causing renal damage in various ways. The aim of this study is to investigate the ectopic lipid accumulation caused b...

    Authors: Yang Yuan, Hong Sun and Zilin Sun
    Citation: Lipids in Health and Disease 2017 16:126
    Content type: Research Published on:

  22. Hepatocellular carcinoma has high incidence and mortality worldwide. Liver is the site of most metabolic biotransformation, which could reflect the status of cells. Most plasma apolipoproteins, endogenous lipi...

    Authors: Lu Tian, Qian Yu, Xing-Hui Gao, Jiong Wu, Xiao-Lu Ma, Qian Dai, Chun-Yan Zhang, Yan Zhou, Yi-Chi Zhang, Bai-Shen Pan, Jian Zhou, Jia Fan, Xin-Rong Yang and Wei Guo
    Citation: Lipids in Health and Disease 2017 16:123
    Content type: Research Published on:

  23. Lowering cholesterol levels decreases the risk of atherosclerotic diseases. Effective ways to stably reduce LDL-C level are warranted in type 2 diabetic patients, a high-risk population for CVD, with various a...

    Authors: Kentaro Sakamoto, Mitsunobu Kawamura, Takayuki Watanabe, Keiko Ashidate, Takahide Kohro, Akira Tanaka, Yasumichi Mori, Motoki Tagami, Tsutomu Hirano, Tsutomu Yamazaki and Teruo Shiba
    Citation: Lipids in Health and Disease 2017 16:122
    Content type: Research article Published on:

  24. Statins are generally well-tolerated and serious side effects are infrequent, but some patients experience adverse events and reduce their statin dose or discontinue treatment altogether. Alirocumab is a highl...

    Authors: Tamio Teramoto, Akira Kondo, Arihiro Kiyosue, Mariko Harada-Shiba, Yasushi Ishigaki, Kimimasa Tobita, Yumiko Kawabata, Asuka Ozaki, Marie T. Baccara-Dinet and Masataka Sata
    Citation: Lipids in Health and Disease 2017 16:121
    Content type: Research Published on:

  25. The present study is aimed to evaluate difference of lipid metabolism related gene single nucleotide polymorphisms (SNPs) with ischemic stroke (IS) in Han and Uighur population of Xinjiang, China.

    Authors: Yun-hua Yue, Ling-yun Liu, Liang Hu, You-mei Li, Jie-ping Mao, Xiao-ying Yang and Na-mu Dila
    Citation: Lipids in Health and Disease 2017 16:120
    Content type: Research Published on:

  26. Previous studies have reported high plasma concentrations of both intestinal apolipoprotein (apo) B-48-containing lipoproteins and PCSK9 in subjects with familial hypercholesterolemia (FH). However, the extent...

    Authors: Jean-Philippe Drouin-Chartier, Jean-Charles Hogue, André J. Tremblay, Jean Bergeron, Benoît Lamarche and Patrick Couture
    Citation: Lipids in Health and Disease 2017 16:119
    Content type: Research Published on:

  28. Autism is neurodevelopmental disorder that is characterized by developmental, behavioral, social and sensory abnormalities. Researchers have focused in last years in immunological alteration and inflammation a...

    Authors: Hanan Qasem, Laila Al-Ayadhi, Hussain Al Dera and Afaf El-Ansary
    Citation: Lipids in Health and Disease 2017 16:117
    Content type: Research Published on:

  29. Given the characteristic atherogenic dyslipidemia of south Indian population and crucial role of APOA1, APOC3, APOA4 and APOA5 genes clustered in 11q23.3 chromosomal region in regulating lipoprotein metabolism an...

    Authors: Rayabarapu Pranavchand and Battini Mohan Reddy
    Citation: Lipids in Health and Disease 2017 16:116
    Content type: Research Published on:

  30. There is a lack of comprehensive patient-datasets regarding prevalence of severe hypertriglyceridemia (sHTG; triglycerides ≥10 mmol/L), frequency of co-morbidities, gene mutations, and gene characterization in...

    Authors: Kjetil Retterstøl, Ingunn Narverud, Randi Selmer, Knut E. Berge, Ingvild V. Osnes, Stine M. Ulven, Bente Halvorsen, Pål Aukrust, Kirsten B. Holven and Per O. Iversen
    Citation: Lipids in Health and Disease 2017 16:115
    Content type: Research Published on:

  31. Currently, two pathogenic pathways describe the role of obesity in osteoarthritis (OA); one through biomechanical stress, and the other by the contribution of systemic inflammation. The aim of this study was t...

    Authors: Daniel Medina-Luna, Mónica Guadalupe Santamaría-Olmedo, Yessica Zamudio-Cuevas, Karina Martínez-Flores, Javier Fernández-Torres, Gabriela Angélica Martínez-Nava, Denise Clavijo-Cornejo, Cristina Hernández-Díaz, Anell Olivos-Meza, Luis Enrique Gomez-Quiroz, María Concepción Gutiérrez-Ruiz, Carlos Pineda, Francisco Blanco, Anthony M. Reginato and Alberto López-Reyes
    Citation: Lipids in Health and Disease 2017 16:114
    Content type: Research Published on:

  32. Nutritional modulation remains central to the management of metabolic syndrome. Intervention with cinnamon in individuals with metabolic syndrome remains sparsely researched.

    Authors: Sonal Gupta Jain, Seema Puri, Anoop Misra, Seema Gulati and Kalaivani Mani
    Citation: Lipids in Health and Disease 2017 16:113
    Content type: Research Published on:

  33. Chronic widespread pain conditions (CWP) such as the pain associated with fibromyalgia syndrome (FMS) are significant health problems with unclear aetiology. Although CWP and FMS can alter both central and per...

    Authors: Niclas Stensson, Bijar Ghafouri, Björn Gerdle and Nazdar Ghafouri
    Citation: Lipids in Health and Disease 2017 16:112
    Content type: Research Published on:

  34. PCSK9 rs505151 and rs11591147 polymorphisms are identified as gain- and loss-of-function mutations, respectively. The effects of these polymorphisms on serum lipid levels and cardiovas...

    Authors: Chengfeng Qiu, Pingyu Zeng, Xiaohui Li, Zhen Zhang, Bingjie Pan, Zhou Y. F. Peng, Yapei Li, Yeshuo Ma, Yiping Leng and Ruifang Chen
    Citation: Lipids in Health and Disease 2017 16:111
    Content type: Research Published on:

  35. Antiretroviral treatment (ART) is associated with dyslipidemia yet little is known about the burden of dyslipidemia in the absence of ART in sub-Saharan Africa. We compared the prevalence and risk factors for ...

    Authors: Anne Njoroge, B. L. Guthrie, Rose Bosire, Mark Wener, James Kiarie and Carey Farquhar
    Citation: Lipids in Health and Disease 2017 16:110
    Content type: Research Published on:

  37. Current day consumers prefer natural antioxidants to synthetic antioxidants because they are more active. However, the activity generally depends on the specific condition and composition of food. The aim of t...

    Authors: Muhammad Sajid Arshad, Ali Imran, Muhammad Tahir Nadeem, Muhammad Sohaib, Farhan Saeed, Faqir Muhammad Anjum, Joong-Ho Kwon and Shahzad Hussain
    Citation: Lipids in Health and Disease 2017 16:108
    Content type: Research Published on:

  38. The aim of this study was to determine the effects of oil quality and antioxidant (AOX) supplementation on sow performance, milk composition and oxidative status.

    Authors: Guoqi Su, Junmei Zhao, Guangbo Luo, Yue Xuan, Zhengfeng Fang, Yan Lin, Shengyu Xu, De Wu, Jun He and Lianqiang Che
    Citation: Lipids in Health and Disease 2017 16:107
    Content type: Research Published on:

  39. Nonalcoholic fatty liver disease (NAFLD) is increasing worldwide as one of the leading causes of chronic liver disease. Sake lees (SL) are secondary products of sake manufacturing and are considered to have be...

    Authors: Hisako Kubo, Masato Hoshi, Takuya Matsumoto, Motoko Irie, Shin Oura, Hiroko Tsutsumi, Yoji Hata, Yasuko Yamamoto and Kuniaki Saito
    Citation: Lipids in Health and Disease 2017 16:106
    Content type: Research Published on:

  41. Like many other cancer patients, most pancreatic carcinoma patients suffer from severe weight loss. As shown in numerous studies with fish oil (FO) supplementation, a minimum daily intake of 1.5 g n-3-fatty ac...

    Authors: Kristin Werner, Daniela Küllenberg de Gaudry, Lenka A. Taylor, Tobias Keck, Clemens Unger, Ulrich T. Hopt and Ulrich Massing
    Citation: Lipids in Health and Disease 2017 16:104
    Content type: Research Published on:

  42. Hypercholesterolemia is a strong determinant of mortality and morbidity associated with cardiovascular diseases and a major contributor to the global disease burden. Mutations in four genes (LDLR, APOB, PCSK9 and...

    Authors: CS Paththinige, ND Sirisena and VHW Dissanayake
    Citation: Lipids in Health and Disease 2017 16:103
    Content type: Review Published on:

  43. Chia (Salvia hispanica L.) is known as power house of omega fatty acids which has great health benefits. It contains up to 78% linolenic acid (ω-3) and 18% linoleic acid (ω-6), which could be a great source of om...

    Authors: Muhammad Nadeem, Muhammad Imran, Imran Taj, Muhammad Ajmal and Muhammad Junaid
    Citation: Lipids in Health and Disease 2017 16:102
    Content type: Research Published on:

  44. Lactic-fermented egg white (LE), produced by lactic acid fermentation of egg white, is an easy-to-consume form of egg white. Here we assessed the effect of daily consumption of LE for 8 weeks on serum total ch...

    Authors: Ryosuke Matsuoka, Mika Usuda, Yasunobu Masuda, Masaaki Kunou and Kazunori Utsunomiya
    Citation: Lipids in Health and Disease 2017 16:101
    Content type: Research Published on:

  45. Type 2 diabetes mellitus is a prevalent systemic disease affecting an important proportion of the population worldwide. It has been suggested that excessive reactive oxygen species generation and therefore dev...

    Authors: Hamida Jdir, Rihab Ben Abdallah Kolsi, Sami Zouari, Khaled Hamden, Nacim Zouari and Nahed Fakhfakh
    Citation: Lipids in Health and Disease 2017 16:100
    Content type: Research Published on:

  46. Punicic acid, a bioactive compound of pomegranate seed oil has gained wide attention for their therapeutic potential. Different studies conducted on animal and human models have revealed that punicic acid is v...

    Authors: Muhmmad Asim Shabbir, Moazzam Rafiq Khan, Muhammad Saeed, Imran Pasha, Anees Ahmed Khalil and Naila Siraj
    Citation: Lipids in Health and Disease 2017 16:99
    Content type: Review Published on:

  47. The so-called “hepatic lipidosis” in turkeys is an acute progressive disease associated with a high mortality rate in a very short time. Dead animals show a massive fatty degeneration of the liver. The cause i...

    Authors: Christian Visscher, Lea Middendorf, Ronald Günther, Alexandra Engels, Christof Leibfacher, Henrik Möhle, Kristian Düngelhoef, Stefan Weier, Wolfram Haider and Dimitri Radko
    Citation: Lipids in Health and Disease 2017 16:98
    Content type: Research Published on:

  48. Postprandial hyperlipemia is recognized as a major cardio-metabolic risk factor, recently linked to the co-absorption of pro-inflammatory lipopolysaccharides with dietary lipids. This causes endotoxemia that i...

    Authors: Cécile Vors, Jocelyne Drai, Gaëlle Pineau, Martine Laville, Hubert Vidal, Fabienne Laugerette and Marie-Caroline Michalski
    Citation: Lipids in Health and Disease 2017 16:97
    Content type: Short report Published on:

  49. Rodent models may guide investigations towards identifying either environmental neuro-toxicants or drugs with neuro-therapeutic effects. This work aims to study the therapeutic effects of bee pollen on brain g...

    Authors: Afaf El-Ansary, Huda S. Al-Salem, Alqahtani Asma and Abeer Al-Dbass
    Citation: Lipids in Health and Disease 2017 16:96
    Content type: Research Published on:

  50. The cyclic adenosine-monophosphate (cAMP) pathway is generally recognized as one of the essential pathways for the adipose conversion of rodent preadipocytes in vitro. However, divergent effects of cAMP on adi...

    Authors: Delin Kong, Jingjing Cui and Juncai Fu
    Citation: Lipids in Health and Disease 2017 16:93
    Content type: Research Published on:
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Lipids in Health and Disease

ISSN: 1476-511X