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  1. Early preclinical diagnosis of COPD is urgent. We proposed that fatty acid composition of red blood cells may serve as a prognostic test for the complications in the chronic respiratory diseases. Fatty acid co...

    Authors: Tatyana P. Novgorodtseva, Yulia K. Denisenko, Natalia V. Zhukova, Marina V. Antonyuk, Vera V. Knyshova and Tatyana A. Gvozdenko
    Citation: Lipids in Health and Disease 2013 12:117
    Content type: Research Published on:

  2. Atherosclerosis has been widely accepted as an inflammatory disease of vascular, adhesion molecules play an important role in the early progression of it. The aim of the present study was to evaluate the effec...

    Authors: Lingxi Kong, Cheng Luo, Xiuying Li, Yuanda Zhou and Haixia He
    Citation: Lipids in Health and Disease 2013 12:115
    Content type: Research Published on:

  3. The Daniel Fast involves dietary modification similar to a purified vegan diet. Although improvements in several health-specific biomarkers have been noted with this plan, the removal of animal products result...

    Authors: Rick J. Alleman Jr, Innocence C. Harvey, Tyler M. Farney and Richard J. Bloomer
    Citation: Lipids in Health and Disease 2013 12:114
    Content type: Research Published on:

  4. Polyunsaturated fatty acids (PUFA) play important roles in brain fatty acid composition and behavior through their effects on neuronal properties and gene expression. The hippocampus plays an important role in...

    Authors: Toktam Hajjar, Yong Meng Goh, Mohamed Ali Rajion, Sharmili Vidyadaran, Tan Ai Li and Mahdi Ebrahimi
    Citation: Lipids in Health and Disease 2013 12:113
    Content type: Research Published on:

  5. Studies in animals showed that PCSK9 is involved in HDL metabolism. We investigated the molecular mechanism by which PCSK9 regulates HDL cholesterol concentration and also whether Pcsk9 inactivation might affect ...

    Authors: Seungbum Choi, Aleksandra Aljakna, Ujala Srivastava, Blake R Peterson, Bin Deng, Annik Prat and Ron Korstanje
    Citation: Lipids in Health and Disease 2013 12:112
    Content type: Research Published on:

  6. Polyunsaturated fatty acids (PUFAs) have positive effect on the regulation of plasma lipids. But the mechanism for them to modulate lipid homeostasis in macrophage is still unclear. In this study, we employed ...

    Authors: Yue Song, Li-Jun Zhang, Hang Li, Yu Gu, Fan-Fan Li, Li-Na Jiang, Fang Liu, Jing Ye and Qing Li
    Citation: Lipids in Health and Disease 2013 12:111
    Content type: Research Published on:

  7. Our previous study demonstrated that the A-allele of the single nucleotide polymorphism (SNP) rs34623097 located in the upstream region of the β2 adrenergic receptor gene (ADRB2) is significantly associated with ...

    Authors: Izumi Naka, Jun Ohashi, Ryosuke Kimura, Tsukasa Inaoka and Yasuhiro Matsumura
    Citation: Lipids in Health and Disease 2013 12:110
    Content type: Research Published on:

  8. Over the past two decades, a striking increase in the number of people with metabolic syndrome (MS) has taken place worldwide. With the elevated risk of not only diabetes but also cardiovascular morbidity and ...

    Authors: Xiaofang Liu, Yong Xue, Chunhua Liu, Qiaoming Lou, Jingfeng Wang, Teruyoshi Yanagita, Changhu Xue and Yuming Wang
    Citation: Lipids in Health and Disease 2013 12:109
    Content type: Research Published on:

  9. Hypoadiponectinemia in lipoatrophy may be related to worsening of hypertension in stroke-prone spontaneously hypertensive rats (SHRSP). One of the beneficial effects of candesartan (Angiotensin II Type 1 recep...

    Authors: Kumiko Takemori, Takao Inoue and Hiroyuki Ito
    Citation: Lipids in Health and Disease 2013 12:108
    Content type: Research Published on:

  10. It is now established that patients with hyperlipidemia have a high risk of atherosclerosis and thrombotic complications, which are two important events responsible for the onset and progression of cardiovascu...

    Authors: Adil Haimeur, Hafida Messaouri, Lionel Ulmann, Virginie Mimouni, Azelarab Masrar, Abdelmjid Chraibi, Gérard Tremblin and Nadia Meskini
    Citation: Lipids in Health and Disease 2013 12:107
    Content type: Research Published on:

  12. During postprandial state, TG concentration is increasing and HDL cholesterol decreasing, leading to a transitory pro-atherosclerotic profile. Previous studies have reported that bicarbonate water improve post...

    Authors: Yassine Zair, Fatima Kasbi-Chadli, Beatrice Housez, Mathieu Pichelin, Murielle Cazaubiel, François Raoux and Khadija Ouguerram
    Citation: Lipids in Health and Disease 2013 12:105
    Content type: Research Published on:

  13. Excessive circular fatty acid, particlarly saturated fatty acid, can result in insulin resistance in skeletal muscle, but other adverse effects of fatty acid accumulation in myocytes remain unclear.

    Authors: Ming Yang, Dandan Wei, Chunfen Mo, Jie Zhang, Xu Wang, Xiaojuan Han, Zhe Wang and Hengyi Xiao
    Citation: Lipids in Health and Disease 2013 12:104
    Content type: Short report Published on:

  14. This post hoc analysis assessed switching to ezetimibe/simvastatin 10/20 mg vs doubling the baseline statin dose to simvastatin 40 mg or atorvastatin 20 mg or switching to rosuvastatin 10 mg in subgroups of obese...

    Authors: Jeffrey B. Rosen, Jose G. Jimenez, Valdis Pirags, Hella Vides, Rachid Massaad, Mary E. Hanson, Philippe Brudi and Joseph Triscari
    Citation: Lipids in Health and Disease 2013 12:103
    Content type: Research Published on:

  15. The long-chain n-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) have human health benefits. Alternatives to fish as sources of EPA and DHA are needed. Oil from the micro-algae Nannochlor...

    Authors: Michael L. Kagan, Annette L. West, Christa Zante and Philip C. Calder
    Citation: Lipids in Health and Disease 2013 12:102
    Content type: Research Published on:

  16. Omega-3 PUFAs are known to have anti-inflammatory properties, and different mechanisms are involved. GPR120 is a G-protein coupled receptor that has recently received attention because of its anti-inflammatory...

    Authors: Kaia Mobraten, Trude M. Haug, Charlotte R. Kleiveland and Tor Lea
    Citation: Lipids in Health and Disease 2013 12:101
    Content type: Research Published on:

  17. The association of adverse health with high fat intake has long been recognized. However, the lack of research focusing on the interrelationship of thyroid and liver function, and the pathogenesis of a high fa...

    Authors: Venus Welch-White, Norma Dawkins, Thomas Graham and Ralphenia Pace
    Citation: Lipids in Health and Disease 2013 12:100
    Content type: Research Published on:

  18. There is considerable interest in dairy products from low-input systems, such as mountain-pasture grazing cows, because these products are believed to be healthier than products from high-input conventional sy...

    Authors: Louise B. Werner, Lars I. Hellgren, Marianne Raff, Søren K. Jensen, Rikke A. Petersen, Tue Drachmann and Tine Tholstrup
    Citation: Lipids in Health and Disease 2013 12:99
    Content type: Research Published on:

  19. Diabetes mellitus is a metabolic disease with multiple complications that causes serious diseases over the years. The condition leads to severe economic consequences and is reaching pandemic level globally. Mu...

    Authors: Sehamuddin Galadari, Anees Rahman, Siraj Pallichankandy, Alaa Galadari and Faisal Thayyullathil
    Citation: Lipids in Health and Disease 2013 12:98
    Content type: Review Published on:

  20. The association of genetic polymorphisms of Tanis with triglyceride concentration in human has not been thoroughly examined. We aimed to investigate the relationship between triglyceride concentrations and Tan...

    Authors: Ying Gao, Xiang Xie, Yi-Tong Ma, Yi-Ning Yang, Xiao-Mei Li, Zhen-Yan Fu, Ying-Ying Zheng, Xiang Ma, Bang-Dang Chen, Fen Liu and Ying Huang
    Citation: Lipids in Health and Disease 2013 12:97
    Content type: Research Published on:

  21. Conjugated linoleic acids (CLA) in general, and in particular the trans- 10,cis- 12 (t 10,c 12-CLA) isomer are potent modulators of milk fat synthesis in dairy cows. Studies in rodents, such as mice, have reveale...

    Authors: Ronny Kramer, Simone Wolf, Tobias Petri, Dirk von Soosten, Sven Dänicke, Eva-Maria Weber, Ralf Zimmer, Juergen Rehage and Gerhard Jahreis
    Citation: Lipids in Health and Disease 2013 12:96
    Content type: Research Published on:

  23. Epidemiological studies have verified the protective role of fish lipids in cardiovascular diseases. However, the effects of fish lipids on health boost remain undefined. Large amounts of by-products, such as ...

    Authors: Caixia Wang, Wenshui Xia, Yanshun Xu, Qixing Jiang, Shanshan Yin, Yuwei Yang and Peipie Yu
    Citation: Lipids in Health and Disease 2013 12:94
    Content type: Research Published on:

  24. To evaluate whether abnormal endothelial function, a common finding in gestational diabetes mellitus (GDM) pregnancies, can be explained by inflammatory cytokines.

    Authors: Ines Mrizak, Amel Arfa, Mariem Fekih, Haythem Debbabi, Ali Bouslema, Imen Boumaiza, Monia Zaouali, Naim A Khan and Zouhair Tabka
    Citation: Lipids in Health and Disease 2013 12:93
    Content type: Research Published on:

  25. Previous data suggested that intake of sodas and other acid beverages might be associated with increased levels of serum triglycerides, lowered HDL cholesterol, and increased formation of mono unsaturated fatt...

    Authors: Arne Torbjørn Høstmark, Marianne Sylvana Haug Lunde and Anna Haug
    Citation: Lipids in Health and Disease 2013 12:92
    Content type: Research Published on:

  26. We evaluated the cholesterol lowering efficacy of low-fat spoonable yoghurt with 1.9 g/d plant stanols as esters on plasma lipid profiles of Turkish subjects with mild to moderate hypercholesterolemia.

    Authors: Zehra Buyuktuncer, Mehmet Fisunoğlu, Gulay Sain Guven, Serhat Unal and Halit Tanju Besler
    Citation: Lipids in Health and Disease 2013 12:91
    Content type: Research Published on:

  27. Carissa opaca leaves are traditionally used in the treatment of male dysfunction and hormonal disorder as well as in oxidative stress in Pakistan and Asia. The present study was designed to assess the protective ...

    Authors: Sumaira Sahreen, Muhammad Rashid Khan, Rahmat Ali Khan and Naseer Ali Shah
    Citation: Lipids in Health and Disease 2013 12:90
    Content type: Research Published on:

  28. The fatty acid mixture of human milk is ideal for the newborn but little is known about its composition in the first few weeks of lactation. Of special interest are the levels of long-chain PUFAs (LCPUFAs), si...

    Authors: Gisela Adrienne Weiss, Heinz Troxler, Glynis Klinke, Daniela Rogler, Christian Braegger and Martin Hersberger
    Citation: Lipids in Health and Disease 2013 12:89
    Content type: Research Published on:

  29. The absorption of dietary long chain fatty acids (LCFA) largely occurs in the jejunum. LCFA are activated via conjugation with Coenzyme A (CoA), a reaction catalyzed by Acyl-CoA synthetases (ACS). Acyl-CoA syt...

    Authors: Nahum Meller, Michelle E Morgan, Winifred PS Wong, Jessica B Altemus and Ephraim Sehayek
    Citation: Lipids in Health and Disease 2013 12:88
    Content type: Short report Published on:

  30. We have previously demonstrated that increased rates of superoxide generation by extra-mitochondrial enzymes induce the activation of the mitochondrial ATP-sensitive potassium channel (mitoKATP) in the livers of ...

    Authors: Luciane C Alberici, Bruno A Paim, Karina G Zecchin, Sandra R Mirandola, Cezar R Pestana, Roger F Castilho, Anibal E Vercesi and Helena CF Oliveira
    Citation: Lipids in Health and Disease 2013 12:87
    Content type: Research Published on:

  31. Nigella sativa belonging to the Ranunculaceae family has been reported to use for thousands of years as protective and curative traditional medicine against a number of diseases. GC-MS analysis of methanolic extr...

    Authors: Shafeeque Ahmad and Zafarul H Beg
    Citation: Lipids in Health and Disease 2013 12:86
    Content type: Research Published on:

  32. Hyperlipidaemia is a major risk factor for coronary artery disease (CAD) and cholesteryl ester transfer protein (CETP) gene polymorphisms are known to be associated with lipid profiles.

    Authors: Yongjian Lu, Naeimeh Tayebi, Hongzhe Li, Nilmani Saha, Hongyuan Yang and Chew-Kiat Heng
    Citation: Lipids in Health and Disease 2013 12:85
    Content type: Research Published on:

  34. Fatty acid synthase (FASN) is frequently activated and overexpressed in human cancers, and plays a crucial role in the carcinogenesis of various cancers. In this study, our aims were to explore the role of FAS...

    Authors: Nan Li, Heng Lu, Chunyan Chen, Xiaodong Bu and Peilin Huang
    Citation: Lipids in Health and Disease 2013 12:83
    Content type: Research Published on:

  35. Obesity is associated with abnormal fasting and postprandial lipids, which may link obesity with atherosclerosis. We explored fasting and postprandial lipids in morbidly obese patients treated with sleeve gast...

    Authors: Elisa Waldmann, Thomas P Hüttl, Burkhard Göke, Reinhold Lang and Klaus G Parhofer
    Citation: Lipids in Health and Disease 2013 12:82
    Content type: Research Published on:

  36. Inflammatory bowel diseases (IBD) are chronic intestinal inflammatory diseases affecting about 1% of western populations. New eating behaviors might contribute to the global emergence of IBD. Although the immu...

    Authors: Nabil Bosco, Viral Brahmbhatt, Manuel Oliveira, Francois-Pierre Martin, Pia Lichti, Frederic Raymond, Robert Mansourian, Sylviane Metairon, Cecil Pace-Asciak, Viktoria Bastic Schmid, Serge Rezzi, Dirk Haller and Jalil Benyacoub
    Citation: Lipids in Health and Disease 2013 12:81
    Content type: Research Published on:

  37. Oxidative modification of low-density lipoprotein (LDL) is a key event in the oxidation hypothesis of atherogenesis. We have previously shown that HDL does not protect LDL from oxidation in vitro, but is in fact ...

    Authors: Tiina Solakivi, Tarja Kunnas, Olli Jaakkola, Jaana Renko, Terho Lehtimäki and Seppo T Nikkari
    Citation: Lipids in Health and Disease 2013 12:80
    Content type: Research Published on:

  38. In recent years the physiological and pathological importance of fatty acids in both the periphery and central nervous system (CNS) has become increasingly apparent. However surprisingly limited research has b...

    Authors: Jade Guest, Manohar Garg, Ayse Bilgin and Ross Grant
    Citation: Lipids in Health and Disease 2013 12:79
    Content type: Research Published on:

  39. We have previously shown that treatment of Zucker rats and mice with diet-induced obesity with dietary docosahexaenoic (DHA) and eicosapentaenoic (EPA) acids in the form of krill oil reduces peripheral levels ...

    Authors: Kjetil Berge, Fabiana Piscitelli, Nils Hoem, Cristoforo Silvestri, Ingo Meyer, Sebastiano Banni and Vincenzo Di Marzo
    Citation: Lipids in Health and Disease 2013 12:78
    Content type: Research Published on:

  40. Serum low-density lipoprotein cholesterol (LDL-C) is one of the most important risk factors for coronary heart disease. The aim of the present study was to investigate the relationship between LDL-C and body m...

    Authors: Takako Shirasawa, Hirotaka Ochiai, Tadahiro Ohtsu, Rimei Nishimura, Aya Morimoto, Hiromi Hoshino, Naoko Tajima and Akatsuki Kokaze
    Citation: Lipids in Health and Disease 2013 12:77
    Content type: Research Published on:

  42. The excessive accumulation of body fat is a major risk factor to develop a variety of metabolic diseases. To investigate the systematic association between the differences in gene expression profiling and adip...

    Authors: Chaowei Zhou, Jie Zhang, Jideng Ma, Anan Jiang, Guoqing Tang, Miaomiao Mai, Li Zhu, Lin Bai, Mingzhou Li and Xuewei Li
    Citation: Lipids in Health and Disease 2013 12:75
    Content type: Research Published on:

  43. Elevated total plasma homocysteine (tHcy) in humans is associated with cardiovascular disease but prevention trials have failed to confirm causality. Reported reasons for this association have been that homocy...

    Authors: Elisabet Söderström, Mats Eliasson, Owe Johnson, Göran Hallmans, Lars Weinehall, Jan-Håkan Jansson and Johan Hultdin
    Citation: Lipids in Health and Disease 2013 12:74
    Content type: Research Published on:

  44. Dietary polyunsaturated fatty acids (PUFA), especially eicosapentaenoic acid (EPA), improve lipid metabolism and contribute to the prevention of vascular diseases such as atherosclerosis. However, EPA in the d...

    Authors: Tharnath Nanthirudjanar, Hidehiro Furumoto, Takashi Hirata and Tatsuya Sugawara
    Citation: Lipids in Health and Disease 2013 12:73
    Content type: Research Published on:

  45. Previous studies have reported that different genotypes of PTPN11 gene (protein tyrosine phosphatase, non-receptor 11) were associated with different levels of serum lipids. The aim of this study was to explore t...

    Authors: Zhi-Fang Jia, Xue-Yuan Cao, Dong-Hui Cao, Fei Kong, Punyaram Kharbuja and Jing Jiang
    Citation: Lipids in Health and Disease 2013 12:72
    Content type: Research Published on:

  46. Polyunsaturated fatty acids (PUFAs) have tumoricidal action, though the exact mechanism of their action is not clear. The results of the present study showed that of all the fatty acids tested, linoleic acid (...

    Authors: Jinfeng Dai, Junhui Shen, Wensheng Pan, Shengrong Shen and Undurti N Das
    Citation: Lipids in Health and Disease 2013 12:71
    Content type: Research Published on:

  47. Variants of the secreted glycoprotein, proprotein convertase subtilisin/kexin 9 (PCSK9), associate with both hypo- and hyper-cholesterolemic phenotypes. Herein, we carried out full exonic sequencing of PCSK9 docu...

    Authors: Janice Mayne, Teik Chye Ooi, Angela Raymond, Marion Cousins, Lise Bernier, Thilina Dewpura, Francine Sirois, Majambu Mbikay, Jean Davignon and Michel Chrétien
    Citation: Lipids in Health and Disease 2013 12:70
    Content type: Research Published on:

  48. Chicken meat nutritional value with regard to fatty acid composition and selenium content depends on the choice of dietary oil and selenium level used in the chickens’ feed. The objective of this study was to ...

    Authors: Nicole F Nyquist, Rune Rødbotten, Magny Thomassen and Anna Haug
    Citation: Lipids in Health and Disease 2013 12:69
    Content type: Research Published on:

  49. Alzheimer’s disease (AD), the most common cause of dementia among neurodegenerative diseases, afflicts millions of elderly people worldwide. In addition to amyloid-beta (Aβ) peptide and phosphorylated tau, lip...

    Authors: Yoko Tajima, Masaki Ishikawa, Keiko Maekawa, Mayumi Murayama, Yuya Senoo, Tomoko Nishimaki-Mogami, Hiroki Nakanishi, Kazutaka Ikeda, Makoto Arita, Ryo Taguchi, Alato Okuno, Ryuta Mikawa, Shumpei Niida, Osamu Takikawa and Yoshiro Saito
    Citation: Lipids in Health and Disease 2013 12:68
    Content type: Research Published on:
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Lipids in Health and Disease

ISSN: 1476-511X