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  1. Post-traumatic ventilator-associated pneumonia (VAP) is a substantial clinical problem that increases hospital costs and typically adds to the duration of mechanical ventilation. We evaluated the impact of VAP...

    Authors: C Michael Dunham and Thomas J Chirichella
    Citation: Lipids in Health and Disease 2011 10:42
    Content type: Research Published on:

  2. In this study we investigated the antiatherogenic effect of dietary enrichment of a combination of extra virgin olive oil (EVO) and seal oil on apolipoprotein E-deficient (apoE-/-).

    Authors: Karl-Erik Eilertsen, Hanne K Mæhre, Katrien Cludts, Jan O Olsen and Marc F Hoylaerts
    Citation: Lipids in Health and Disease 2011 10:41
    Content type: Research Published on:

  3. Chronic, low-grade inflammation provides a link between normal ageing and the pathogenesis of age-related diseases. A series of in vitro tests confirmed the strong anti-inflammatory activities of known inhibitors...

    Authors: Asaf A Qureshi, Julia C Reis, Nilofer Qureshi, Christopher J Papasian, David C Morrison and Daniel M Schaefer
    Citation: Lipids in Health and Disease 2011 10:39
    Content type: Research Published on:

  4. During the past decade, proprotein convertase subtilisin kexin type 9 (PCSK9) has been identified as a key regulator of serum LDL-cholesterol (LDL-C) levels. PCSK9 is secreted by the liver into the plasma and ...

    Authors: Robert J Konrad, Jason S Troutt and Guoqing Cao
    Citation: Lipids in Health and Disease 2011 10:38
    Content type: Review Published on:

  5. It is well known that high fat diets (HFDs) induce obesity and an increase in proinflammatory adipokines. Interleukin-6 (IL-6) is considered the major inflammatory mediator in obesity. Obesity is associated wi...

    Authors: Fábio S Lira, José C Rosa, Claudio A Cunha, Eliane B Ribeiro, Claudia Oller do Nascimento, Lila M Oyama and João F Mota
    Citation: Lipids in Health and Disease 2011 10:37
    Content type: Research Published on:

  6. Citrus flavonoids have been shown to decrease plasma lipid levels, improve glucose tolerance, and attenuate obesity. One possible mechanism underlying these physiological effects is reduction of hepatic levels...

    Authors: LaNita A Nichols, Daniel E Jackson, John A Manthey, Shivendra D Shukla and Lené J Holland
    Citation: Lipids in Health and Disease 2011 10:36
    Content type: Short report Published on:

  7. The role of pro-inflammatory lipids in systemic immune activation in HIV infection remains largely unknown. We hypothesized that HIV-1-infected persons on antiretroviral therapy would have pro-inflammatory hig...

    Authors: Theodoros Kelesidis, Otto O Yang, Judith S Currier, Kaveh Navab, Alan M Fogelman and Mohamad Navab
    Citation: Lipids in Health and Disease 2011 10:35
    Content type: Short report Published on:

  8. Several common genetic polymorphisms in the low density lipoprotein receptor (LDL-R) gene have associated with modifications of serum total cholesterol (TC) and low density lipoprotein cholesterol (LDL-C) leve...

    Authors: Xing-Jiang Long, Rui-Xing Yin, Ke-La Li, Wan-Ying Liu, Lin Zhang, Xiao-Li Cao, Lin Miao, Dong-Feng Wu, Lynn Htet Htet Aung and Xi-Jiang Hu
    Citation: Lipids in Health and Disease 2011 10:34
    Content type: Research Published on:

  9. Evidence of predictive power of various fatty acids on the risk of metabolic syndrome was scanty. We evaluated the role of various fatty acids, including saturated fat, monounsaturated fat, transfat, n-6 fatty...

    Authors: Kuo-Liong Chien, Chia-Lun Chao, Chen-Hong Kuo, Hung-Ju Lin, Pi-Hua Liu, Pei-Rony Chen, Hsiu-Ching Hsu, Bai-Chin Lee, Yuan-Teh Lee and Ming-Fong Chen
    Citation: Lipids in Health and Disease 2011 10:33
    Content type: Research Published on:

  10. Mammalian sPLA2-IB are well characterized. In contrast, much less is known about aquatic ones. The aquatic world contains a wide variety of living species and, hence represents a great potential for discoverin...

    Authors: Abir Ben Bacha, Aida Karray, Emna Bouchaala, Youssef Gargouri and Yassine Ben Ali
    Citation: Lipids in Health and Disease 2011 10:32
    Content type: Research Published on:

  11. Heme oxygenase-1 (HO-1), an antioxidant defense enzyme, has been shown to protect against oxidant-induced liver injury. However, its role on liver fibrosis remains unclear. This study aims to elucidate the eff...

    Authors: Rong Qi Wang, Yue Min Nan, Wen Juan Wu, Ling Bo Kong, Fang Han, Su Xian Zhao, Li Kong and Jun Yu
    Citation: Lipids in Health and Disease 2011 10:31
    Content type: Research Published on:

  12. In the present work we determined the total phenolic content of Aloe vera leaf skin (AVLS) extracts by using various solvents (hexane, chloroform-ethanol (1/1), ethyl acetate, butanol and water). We have also eva...

    Authors: Maher Kammoun, Sonia Miladi, Yassine Ben Ali, Mohamed Damak, Youssef Gargouri and Sofiane Bezzine
    Citation: Lipids in Health and Disease 2011 10:30
    Content type: Research Published on:

  13. Licorice flavonoid oil (LFO) has been reported to minimize visceral adipose tissue gain in obese mice and to result in a decrease in body weight and body fat in humans; the effects of which may be more pronoun...

    Authors: Zach W Bell, Robert E Canale and Richard J Bloomer
    Citation: Lipids in Health and Disease 2011 10:29
    Content type: Research Published on:

  17. In the water maze test, oral administration with 1,2-dilynoleoyl-sn-glycero-3-phosphocholine (DLPhtCho)(5 mg/kg) alone or DLPhtCho (5 mg/kg) plus 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPhtCho)(5 mg/k...

    Authors: Tetsu Nagata, Takahiro Yaguchi and Tomoyuki Nishizaki
    Citation: Lipids in Health and Disease 2011 10:25
    Content type: Research Published on:

    The Erratum to this article has been published in Lipids in Health and Disease 2015 14:115

  18. The turkey pancreatic lipase (TPL) was purified from delipidated pancreases. Some biochemical properties and kinetic studies were determined using emulsified system and monomolecular film techniques. Those stu...

    Authors: Madiha Bou Ali, Yassine Ben Ali, Aida Karray, Ahmed Fendri and Youssef Gargouri
    Citation: Lipids in Health and Disease 2011 10:24
    Content type: Research Published on:

  19. Treatment with atorvastatin (ATO) or dietary control has been demonstrated to benefit patients with non-alcoholic fatty liver disease (NAFLD) and hyperlipidemia. However, little is known on whether combination...

    Authors: Guiyuan Ji, Xihong Zhao, Liang Leng, Peiyi Liu and Zhuoqin Jiang
    Citation: Lipids in Health and Disease 2011 10:23
    Content type: Research Published on:

  20. Although lipids transfer through placenta is very limited, modification in dietary fatty acids can lead to implications in fetal and postnatal development. Trans fatty acid (TFA) intake during gestation and lacta...

    Authors: Juliana L de Oliveira, Lila M Oyama, Ana Cláudia L Hachul, Carolina Biz, Eliane B Ribeiro, Claudia M Oller do Nascimento and Luciana P Pisani
    Citation: Lipids in Health and Disease 2011 10:22
    Content type: Research Published on:

  21. Coronary angiography is the current standard method to evaluate coronary atherosclerosis in patients with suspected angina pectoris, but non-invasive CT scanning of the coronaries are increasingly used for the...

    Authors: Anne P Toft-Petersen, Hans H Tilsted, Jens Aarøe, Klaus Rasmussen, Thorkil Christensen, Bruce A Griffin, Inge V Aardestrup, Annette Andreasen and Erik B Schmidt
    Citation: Lipids in Health and Disease 2011 10:21
    Content type: Research Published on:

  22. Obesity, type 2 diabetes and hyperlipidemia frequently coexist and are associated with significantly increased morbidity and mortality. Consumption of refined carbohydrate and particularly fructose has increas...

    Authors: Danshan Huang, Tania Dhawan, Stephen Young, William H Yong, Laszlo G Boros and Anthony P Heaney
    Citation: Lipids in Health and Disease 2011 10:20
    Content type: Research Published on:

  24. Modification of fatty acids (FA) composition in erythrocytes lipids as an early indicator of the development of arterial hypertension (AH) and lipid disorders.

    Authors: Tatyana P Novgorodtseva, Tatyana A Kantur, Yulia K Karaman, Marina V Antonyuk and Natalia V Zhukova
    Citation: Lipids in Health and Disease 2011 10:18
    Content type: Review Published on:

  25. To investigate the effect of triglyceride (TG) integrates with plasma major components of apolipoproteins in HDL subclasses distribution and further elicited the TG-apolipoproteins (apos) interaction in the pr...

    Authors: Li Tian, Yanhua Xu, Mingde Fu, Tao Peng, Yinghui Liu and Shiyin Long
    Citation: Lipids in Health and Disease 2011 10:17
    Content type: Research Published on:

  26. Eicosanoids are major players in the pathogenesis of several common diseases, with either overproduction or imbalance (e.g. between thromboxanes and prostacyclins) often leading to worsening of disease symptoms. ...

    Authors: Olav A Christophersen and Anna Haug
    Citation: Lipids in Health and Disease 2011 10:16
    Content type: Review Published on:

  27. Trans fat are not desirable in many aspects on health maintenance. Low trans structured fats have been reported to be relatively more safe than trans fats.

    Authors: Yun-Young Cho, Eun-Young Kwon, Hye-Jin Kim, Seon-Min Jeon, Ki-Teak Lee and Myung-Sook Choi
    Citation: Lipids in Health and Disease 2011 10:15
    Content type: Short report Published on:

  28. Several genetic variants in the ATP-binding cassette transporter A1 (ABCA1) gene have associated with modifications of serum high-density lipoprotein cholesterol (HDL-C) levels and the susceptibility for coron...

    Authors: Xiao-Li Cao, Rui-Xing Yin, Dong-Feng Wu, Lin Miao, Lynn Htet Htet Aung, Xi-Jiang Hu, Qing Li, Ting-Ting Yan, Wei-Xiong Lin and Shang-Ling Pan
    Citation: Lipids in Health and Disease 2011 10:14
    Content type: Research Published on:

  29. Lipoprotein-associated phospholipase A2 (Lp-PLA2) is a recently identified and potentially useful plasma biomarker for cardiovascular and atherosclerotic diseases. However, the correlation between the Lp-PLA2 act...

    Authors: Hui-ping Gong, Yi-meng Du, Li-na Zhong, Zhao-qiang Dong, Xin Wang, Yong-jun Mao and Qing-hua Lu
    Citation: Lipids in Health and Disease 2011 10:13
    Content type: Research Published on:

  30. Visceral Fat Area (VFA) is an independent predictor of coronary disease. While low density lipoprotein cholesterol (LDL-C) is used to determine risk and guide therapy, its accuracy fails in obese patients who ...

    Authors: Michel R Hoenig, Gary Cowin, Raymond Buckley, Christine McHenery and Allan Coulthard
    Citation: Lipids in Health and Disease 2011 10:12
    Content type: Research Published on:

  31. Adiponectin is the most abundant plasma protein synthesized for the most part in adipose tissue, and it is an insulin-sensitive hormone, playing a central role in glucose and lipid metabolism. In addition, it ...

    Authors: Cristiane de Oliveira, Ana BM de Mattos, Carolina Biz, Lila M Oyama, Eliane B Ribeiro and Cláudia Maria Oller do Nascimento
    Citation: Lipids in Health and Disease 2011 10:11
    Content type: Research Published on:

  32. n-3 and n-6 polyunsaturated fatty acids (PUFAs) are the two major classes of PUFAs encountered in the diet, and both classes of fatty acids are required for normal human health. Moreover, PUFAs have effects on di...

    Authors: Maria Notarnicola, Caterina Messa, Maria G Refolo, Valeria Tutino, Angelica Miccolis and Maria G Caruso
    Citation: Lipids in Health and Disease 2011 10:10
    Content type: Research Published on:

  33. The Roma (Gypsies) are a transnational minority, founder population characterized by unique genetic background modeled by culturally determined endogamy. The present study explores whether the widely found car...

    Authors: Hrvojka Marija Zeljko, Tatjana Škarić-Jurić, Nina Smolej Narančić, Željka Tomas, Ana Barešić, Marijana Peričić Salihović, Boris Starčević and Branka Janićijević
    Citation: Lipids in Health and Disease 2011 10:9
    Content type: Short report Published on:

  34. Statins are first-line pharmacotherapeutic agents for hypercholesterolemia treatment in humans. However the effects of statins on atherosclerosis in mouse models are very paradoxical. In this work, we wanted t...

    Authors: Guohua Song, Jia Liu, Zhenmei Zhao, Yang Yu, Hua Tian, Shutong Yao, Guoli Li and Shucun Qin
    Citation: Lipids in Health and Disease 2011 10:8
    Content type: Research Published on:

  35. Sphingomyelin synthase 2 (SMS2) contributes to de novo sphingomyelin (SM) biosynthesis. Its activity is related to SM levels in the plasma and the cell membrane. In this study, we investigated the possibility ...

    Authors: Xiaogang Wang, Jibin Dong, Yarui Zhao, Yue Li and Manping Wu
    Citation: Lipids in Health and Disease 2011 10:7
    Content type: Research Published on:

  36. Obesity became major health problem in the world, the objective of this work was to examine the effect of high sucrose and high fat diet to induce obesity on antioxidant defense system, biochemical changes in ...

    Authors: Kamal A Amin, Hamdy H Kamel and Mohamed A Abd Eltawab
    Citation: Lipids in Health and Disease 2011 10:6
    Content type: Research Published on:

  37. Proprotein convertase subtilisin-like kexin type 9 (PCSK9) plays a key role in regulating plasma low-density lipoprotein cholesterol (LDL-C) levels. However, the association of E670G (rs505151) polymorphism in...

    Authors: Lynn Htet Htet Aung, Rui-Xing Yin, Lin Miao, Xi-Jiang Hu, Ting-Ting Yan, Xiao-Li Cao, Dong-Feng Wu, Qing Li, Shang-Ling Pan and Jin-Zhen Wu
    Citation: Lipids in Health and Disease 2011 10:5
    Content type: Research Published on:

  38. The presence of chicken group-IIA PLA2 (ChPLA2-IIA) in the intestinal secretion suggests that this enzyme plays an important role in systemic bactericidal defence. We have analyzed the bactericidal activity of...

    Authors: Aida Karray, Yassine Ben Ali, Youssef Gargouri and Sofiane Bezzine
    Citation: Lipids in Health and Disease 2011 10:4
    Content type: Research Published on:

  39. Metabolic syndrome is a disease that today affects millions of people around the world. Therefore, it is of great interest to implement more effective procedures for preventing and treating this disease. In se...

    Authors: Ana C Ghezzi, Lucieli T Cambri, Carla Ribeiro, José D Botezelli and Maria AR Mello
    Citation: Lipids in Health and Disease 2011 10:3
    Content type: Research Published on:

  40. Inflammation process plays an important role in the development of atherosclerosis. Hypercholesterolemia is one of the major risk factors for atherosclerosis. The present study aimed to evaluate the effect of ...

    Authors: Adel A Amran, Zaiton Zakaria, Faizah Othman, Srijit Das, Hesham M Al-Mekhlafi and Nor-Anita MM Nordin
    Citation: Lipids in Health and Disease 2011 10:2
    Content type: Research Published on:

  41. Oxidized low-density lipoprotein (oxLDL) uptake by macrophages plays an important role in foam cell formation. It has been suggested the presence of heterogeneous subsets of macrophage, such as M1 and M2, in h...

    Authors: Kuniaki Hirose, Kazuhisa Iwabuchi, Kazunori Shimada, Takashi Kiyanagi, Chihiro Iwahara, Hitoshi Nakayama and Hiroyuki Daida
    Citation: Lipids in Health and Disease 2011 10:1
    Content type: Research Published on:

  42. To report changes in body weight, total and central fat mass, metabolic, hormonal and inflammatory parameters in overweight people who participated in a six months weight loss intervention associating diet man...

    Authors: Frédéric Dutheil, Bruno Lesourd, Daniel Courteix, Robert Chapier, Eric Doré and Gérard Lac
    Citation: Lipids in Health and Disease 2010 9:148
    Content type: Research Published on:

  43. Oxidized low-density lipoprotein (LDL) may act as an atheroprotective (anti-atherosclerotic) agent under some conditions. While the α1-antitrypsin (AT)-LDL complex is considered a type of oxidized LDL, its cli...

    Authors: Kazuhiko Kotani, Toshiyuki Yamada and Nobuyuki Taniguchi
    Citation: Lipids in Health and Disease 2010 9:147
    Content type: Research Published on:

  44. Abnormalities in lipid metabolism and transport are hallmarks in analbuminemic Nagase rats (NAR) and humans. Triglyceridemia is nearly 3- to 5-fold higher in female NAR than in control Sprague-Dawley rats (SDR...

    Authors: Tiago R Figueira, Aníbal E Vercesi and Helena CF Oliveira
    Citation: Lipids in Health and Disease 2010 9:146
    Content type: Research Published on:

  45. The association of peroxisome proliferator-activated receptor delta (PPARD) +294T > C polymorphism and serum lipid levels is inconsistent in several previous studies. Bai Ku Yao is an isolated subgroup of the ...

    Authors: Lin Miao, Rui-Xing Yin, Dong-Feng Wu, Xiao-Li Cao, Qing Li, Xi-Jiang Hu, Ting-Ting Yan, Lynn Htet Htet Aung, De-Zhai Yang and Wei-Xiong Lin
    Citation: Lipids in Health and Disease 2010 9:145
    Content type: Research Published on:

  46. Type 2 diabetes is associated with significant cardiovascular morbidity and mortality. Although low-density lipoprotein cholesterol levels may be normal in patients with type 2 diabetes, insulin resistance dri...

    Authors: Krishnaswami Vijayaraghavan
    Citation: Lipids in Health and Disease 2010 9:144
    Content type: Review Published on:

  47. Inflammation has been implicated in cardiovascular disease, and the important role of proteasomes in the development of inflammation and other macrophage functions has been demonstrated. Tocotrienols are poten...

    Authors: Asaf A Qureshi, Julia C Reis, Christopher J Papasian, David C Morrison and Nilofer Qureshi
    Citation: Lipids in Health and Disease 2010 9:143
    Content type: Research Published on:

  48. Statins induces cell cycle arrest, apoptosis, reduction of angiogenic factors, inhibition of the endothelial growth factor, impairing tissue adhesion and attenuation of the resistance mechanisms. The aim of th...

    Authors: Giovani M Favero, Michel F Otuki, Karen A Oliveira, Milton S Bohatch Jr, Primavera Borelli, Francisco E Barros, Durvanei A Maria, Daniel Fernandes and Sergio P Bydlowski
    Citation: Lipids in Health and Disease 2010 9:142
    Content type: Research Published on:

  50. Because abdominal obesity is predisposed to various metabolic disorders, it is of major importance to assess and track the changes with time of this specific fat mass. The main issue for clinicians or research...

    Authors: Maude Gerbaix, Lore Metz, Emeline Ringot and Daniel Courteix
    Citation: Lipids in Health and Disease 2010 9:140
    Content type: Research Published on:
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Lipids in Health and Disease

ISSN: 1476-511X