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  1. Content type: Research

    It has been observed that ras-transformed cell lines in culture have a higher phosphatidylcholine (PC) biosynthesis rate as well as higher PC-degradation rate (increased PC-turnover) than normal cells. In corr...

    Authors: Lenka A. Taylor, Jann Arends, Arwen K. Hodina, Clemens Unger and Ulrich Massing

    Citation: Lipids in Health and Disease 2007 6:17

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  2. Content type: Short paper

    Exercise has been prescribed in the treatment and control of dyslipidemias and cholesterolemia, however, lipid responses to different training frequencies in hypercholesterolemic men have been inconsistent. We...

    Authors: Ricardo L. F. Guerra, Wagner L. Prado, Nádia C. Cheik, Fabiana P. Viana, João Paulo Botero, Regina C. Vendramini, Iracilda Z. Carlos, Elizeu A. Rossi and Ana R. Dâmaso

    Citation: Lipids in Health and Disease 2007 6:16

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  3. Content type: Short paper

    Dietary supplement use is widespread in developed nations. In particular, patients who utilize mental health services also report frequent consumption of dietary supplements, often in relation to management of...

    Authors: Martin A Katzman, Leslie Jacobs, Madalyn Marcus, Monica Vermani and Alan C Logan

    Citation: Lipids in Health and Disease 2007 6:14

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  4. Content type: Research

    Docosahexaenoic acid (22:6n-3, DHA) and n-6 docosapentaenoic acid (22:5n-6, DPAn-6) are highly unsaturated fatty acids (HUFA, ≥ 20 carbons, ≥ 3 double bonds) that differ by a single carbon-carbon double bond a...

    Authors: Ken D Stark, Sun-Young Lim and Norman Salem Jr

    Citation: Lipids in Health and Disease 2007 6:13

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  5. Content type: Commentary

    To translate science into clinical practice we must first assess the quality of care that is being delivered. The resulting information about qualitative and quantitative parameters can then be assessed. Ultim...

    Authors: Allam Appa Rao and Gumpeny Ramachandra Sridhar

    Citation: Lipids in Health and Disease 2007 6:12

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  6. Content type: Research

    The effects of 24(S),25-epoxycholesterol (24,25EC) on aspects of cholesterol homeostasis is well-documented. When added to cells, 24,25EC decreases cholesterol synthesis and up-regulates cholesterol efflux genes,...

    Authors: Jenny Wong, Carmel M Quinn and Andrew J Brown

    Citation: Lipids in Health and Disease 2007 6:10

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  7. Content type: Research

    Several trials from different populations have reported that non-high density lipoprotein cholesterol (non-HDL-C) has more predictive power than low-density lipoprotein cholesterol (LDL-C) in detecting coronar...

    Authors: Nasser M Al-Daghri, Omar S Al-Attas and Khalid Al-Rubeaan

    Citation: Lipids in Health and Disease 2007 6:9

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  8. Content type: Research

    A single session of exercise has been reported to reduce fasting and postprandial triacylglycerol concentrations on the subsequent day. It is possible that exercise also reduces chylomicron particle number, wh...

    Authors: Anthony P James, Karin Slivkoff-Clark and John CL Mamo

    Citation: Lipids in Health and Disease 2007 6:8

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  9. Content type: Research

    Statin-related skeletal muscle disorders range from benign myalgias – such as non-specific muscle aches or joint pains without elevated serum creatinine kinase (CK) concentration – to true myositis with >10-fo...

    Authors: Jisun Oh, Matthew R Ban, Brooke A Miskie, Rebecca L Pollex and Robert A Hegele

    Citation: Lipids in Health and Disease 2007 6:7

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  10. Content type: Short paper

    Feeding oxidized fats causes activation of peroxisome proliferator-activated receptor α (PPARα) in the liver of rats. However, whether feeding oxidized fat during pregnancy also results in activation of PPARα ...

    Authors: Robert Ringseis, Anke Gutgesell, Corinna Dathe, Corinna Brandsch and Klaus Eder

    Citation: Lipids in Health and Disease 2007 6:6

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  11. Content type: Research

    Obesity is generally linked to complications in lipid metabolism and oxidative stress. The aim of this study was to compare the effect of a proprietary extract of Cissus quadrangularis (CQR-300) to that of a prop...

    Authors: Julius E Oben, Damaris Mandob Enyegue, Gilles I Fomekong, Yves B Soukontoua and Gabriel A Agbor

    Citation: Lipids in Health and Disease 2007 6:4

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  12. Content type: Research

    Mice that lack acyl CoA:diacylglycerol acyltransferase (Dgat1-/- mice) are reported to have a reduced body fat content and improved glucose tolerance and insulin sensitivity. Studies so far have focussed on male ...

    Authors: Steven JY Wang, Claire Cornick, Jacqueline O'Dowd, Michael A Cawthorne and Jonathan R S Arch

    Citation: Lipids in Health and Disease 2007 6:2

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  13. Content type: Research

    Cardiovascular disease (CVD) is the Nation's leading killer for both men and women among all racial and ethnic groups. Development and progression of CVD is linked to the presence of risk factors such as hyper...

    Authors: Danik M Martirosyan, Lidia A Miroshnichenko, Svetlana N Kulakova, Ala V Pogojeva and Vladimir I Zoloedov

    Citation: Lipids in Health and Disease 2007 6:1

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  14. Content type: Short paper

    Severe combined hyperlipidaemia has occasionally been associated with infiltration of tissues in addition to arteries and the skin. We report a woman with Type 2 diabetes mellitus (DM) and severe combined hype...

    Authors: Rachel A Davey, Niall C Tebbutt, Jenny M Favaloro, David N O'Neal, Derek Rae, Jeffrey D Zajac and James D Best

    Citation: Lipids in Health and Disease 2006 5:29

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  15. Content type: Short paper

    Alzheimer's disease and type 2 diabetes mellitus tend to occur together. We sought to identify protein(s) common to both conditions that could suggest a possible unifying pathogenic role. Using human neuronal ...

    Authors: Appa Rao Allam, Gumpeny Ramachandra Sridhar, Hanuman Thota, Changalasetty Suresh Babu, Akula Siva Prasad and Ch Divakar

    Citation: Lipids in Health and Disease 2006 5:28

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  16. Content type: Research

    The lipodystrophic syndrome (LD) is a disorder resulting from selective damage of adipose tissue by antiretroviral drugs included in therapy controlling human-immunodeficiency-virus-1. In the therapy cocktail ...

    Authors: Christel Gentil, Sébastien Le Jan, Josette Philippe, Jacques Leibowitch, Pierre Sonigo, Stéphane Germain and France Piétri-Rouxel

    Citation: Lipids in Health and Disease 2006 5:27

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  17. Content type: Research

    The glycosphingolipid sulfatide has previously been found in several mammalian tissues, but information on the uptake of exogenously administered sulfatide in different organs in vivo is limited. In pancreatic be...

    Authors: Maria Blomqvist, Thomas Osterbye, Jan-Eric Månsson, Karsten Buschard and Pam Fredman

    Citation: Lipids in Health and Disease 2006 5:26

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  18. Content type: Research

    It has been shown that calcifying vesicles play an important role in aortic calcification and that cholesterol content in the isolated vesicle fraction is increased when rabbits are fed supplemental cholestero...

    Authors: Howard HT Hsu and Nathan C Culley

    Citation: Lipids in Health and Disease 2006 5:25

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  19. Content type: Research

    Once considered a problem of developed countries, obesity and obesity-related complications (such as metabolic syndrome) are rapidly spreading around the globe. The purpose of the present study was to investig...

    Authors: Julius Oben, Dieudonne Kuate, Gabriel Agbor, Claudia Momo and Xavio Talla

    Citation: Lipids in Health and Disease 2006 5:24

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  20. Content type: Research

    Triacylglyerol-rich very low density lipoprotein (VLDL) particles are the primary carriers of fatty acids in the circulation and as such serve as a rich energy source for peripheral tissues. Receptor-mediated ...

    Authors: Larissa C Wilsie, Amanda M Gonzales and Robert A Orlando

    Citation: Lipids in Health and Disease 2006 5:23

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  21. Content type: Short paper

    HMG-CoA reductase and the LDL receptor are ubiquitously expressed in major tissues. Since the liver plays a major role in regulating circulating LDL, it is usually of interest to measure the effects of drug or...

    Authors: Dimple Aggarwal, Hedley C Freake, Ghada A Soliman, Amrita Dutta and Maria-Luz Fernandez

    Citation: Lipids in Health and Disease 2006 5:22

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  22. Content type: Research

    Arylsulfatase A (ASA)-deficient mice are a model for the lysosomal storage disorder metachromatic leukodystrophy. This lipidosis is characterised by the lysosomal accumulation of the sphingolipid sulfatide. St...

    Authors: S Franken, D Wittke, JE Mansson, R D'Hooge, PP De Deyn, R Lüllmann-Rauch, U Matzner and V Gieselmann

    Citation: Lipids in Health and Disease 2006 5:21

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  23. Content type: Short paper

    Adaptation of assays on dried blood has advantages of ease of collection, transportation, minimal invasiveness and requirement of small volume. A method for extraction and estimation of triglyceride from blood...

    Authors: Rizwana Quraishi, Ramakrishnan Lakshmy, Dorairaj Prabhakaran, Ashok Kumar Mukhopadhyay and Bansilal Jailkhani

    Citation: Lipids in Health and Disease 2006 5:20

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  24. Content type: Research

    Lipoprotein Lipase (LPL), a key enzyme in lipid metabolism, catalyzes the hydrolysis of triglycerides (TG) from TG-rich lipoproteins, and serves a bridging function that enhances the cellular uptake of lipopro...

    Authors: Shu-Fen Wung, Medha V Kulkarni, Clive R Pullinger, Mary J Malloy, John P Kane and Bradley E Aouizerat

    Citation: Lipids in Health and Disease 2006 5:19

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  25. Content type: Research

    Vascular calcification is implicated in myocardial infarction, instability and rigidity of the aortic wall, and bioprosthetic failures. Although an increase in the calcium (Ca) content in atherogenic diets has...

    Authors: Howard HT Hsu and Nathan C Culley

    Citation: Lipids in Health and Disease 2006 5:16

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  26. Content type: Research

    Tegaserod is effective in treating IBS patients with constipation, and does not alter gallbladder motility in healthy individuals or in patients with IBS. However, it is not known if tegaserod affects the bili...

    Authors: Ronald Mathison, Eldon Shaffer, Hans-Juergen Pfannkuche and David Earnest

    Citation: Lipids in Health and Disease 2006 5:15

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  27. Content type: Research

    Hyperlipidemia is a major risk factor in etiology of cardiovascular disease. Previous studies have shown association between vegetarian diet and low total serum cholesterol as well as LDL-cholesterol which is ...

    Authors: Olugbenga Adebawo, Bamidele Salau, Esther Ezima, Olamilekan Oyefuga, Emmanuel Ajani, Gbolahan Idowu, Adekunle Famodu and Odutola Osilesi

    Citation: Lipids in Health and Disease 2006 5:14

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  28. Content type: Research

    A new water-based topical formulation is presented that aims at providing good penetration properties for both lipophilic and hydrophilic drugs with as small a disturbance of the skin barrier function as possi...

    Authors: Mats Silvander, Lovisa Ringstad, Ruby Ghadially and Thomas Sköld

    Citation: Lipids in Health and Disease 2006 5:12

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  29. Content type: Research

    Apolipoprotein AV (ApoAV) gene variant, -1131T>C, is associated with increased triglyceride concentrations in all ethnic groups studied. An MseI based RFLP analysis is the most commonly used method for genotyping...

    Authors: Kirsten J Ward, Sian Ellard, Chittaranjan S Yajnik, Timothy M Frayling, Andrew T Hattersley, Prathyusha NS Venigalla and Giriraj R Chandak

    Citation: Lipids in Health and Disease 2006 5:11

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  30. Content type: Research

    Herein, we expand our previous work on the effects of long chain polyunsaturated fatty acids (LC-PUFA) on the murine hepatic transcriptome using novel statistical and bioinformatic approaches for evaluating mi...

    Authors: Alvin Berger, Matthew A Roberts and Bruce Hoff

    Citation: Lipids in Health and Disease 2006 5:10

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  31. Content type: Research

    previous studies have indicated on association between shift work and lipid profile disturbances. Lipid profile disturbances could be due to internal desynchronization. The aim of this study was to analyze whe...

    Authors: Masoumeh Ghiasvand, Ramin Heshmat, Reza Golpira, Vahid Haghpanah, Ali Soleimani, Payman Shoushtarizadeh, Seyed Mohammad Tavangar and Bagher Larijani

    Citation: Lipids in Health and Disease 2006 5:9

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  32. Content type: Research

    The Friedewald formula (LDL-F) for the estimation of low-density lipoprotein (LDL) cholesterol concentrations is the most often used formula in clinical trials and clinical practice. However, much concern has ...

    Authors: Irene Gazi, Vasilis Tsimihodimos, Theodosios D Filippatos, Vasilios G Saougos, Eleni T Bairaktari, Alexandros D Tselepis and Moses Elisaf

    Citation: Lipids in Health and Disease 2006 5:8

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  33. Content type: Research

    There is an increase in obesity among the population of industrialized countries, and dietary supplementation with Conjugated Linoleic Acid (CLA) has been reported to lower body fat mass. However, weight loss ...

    Authors: Jameela Banu, Arunabh Bhattacharya, Mizanur Rahman, Marianne O'Shea and Gabriel Fernandes

    Citation: Lipids in Health and Disease 2006 5:7

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  34. Content type: Research

    A high dietary intake of n-6 compared to n-3 fatty acids (FAs) may promote the production of pro-inflammatory eicosanoids and cytokines. In two recent studies, short-term (10-day) duodenal administration of n-...

    Authors: Tormod Bjørkkjær, Johan G Brun, Merete Valen, Gülen Arslan, Ragna Lind, Linn A Brunborg, Arnold Berstad and Livar Frøyland

    Citation: Lipids in Health and Disease 2006 5:6

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  35. Content type: Research

    The strong causal role of hypercholesterolaemia on the progression of atherosclerosis and subsequently on the development of cardiovascular disease is well described. Main aim of this study was to evaluate the...

    Authors: George A Milias, Demosthenes B Panagiotakos, Christos Pitsavos, Dimitra Xenaki, George Panagopoulos and Christodoulos Stefanadis

    Citation: Lipids in Health and Disease 2006 5:5

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  36. Content type: Review

    Liver plays a key role in the metabolism of plasma apolipoproteins, endogenous lipids and lipoproteins. Hepatocellular carcinoma (HCC) is one of the most common fatal malignant tumors in China and in other Sou...

    Authors: Jingting Jiang, Peter Nilsson-Ehle and Ning Xu

    Citation: Lipids in Health and Disease 2006 5:4

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  37. Content type: Research

    The heart is rich in cardiolipin, a phospholipid acylated in four sites, predominately with linoleic acid. Whether or not aging alters the composition of cardiolipin acyl chains is controversial. We therefore ...

    Authors: Ho-Joo Lee, Jana Mayette, Stanley I Rapoport and Richard P Bazinet

    Citation: Lipids in Health and Disease 2006 5:2

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  38. Content type: Review

    Homocysteine is an independent risk factor for cardiovascular diseases. It is also known to be associated with a variety of complex disorders. While there are a large number of independent studies implicating ...

    Authors: Priyanka Sharma, RD Senthilkumar, Vani Brahmachari, Elayanambi Sundaramoorthy, Anubha Mahajan, Amitabh Sharma and Shantanu Sengupta

    Citation: Lipids in Health and Disease 2006 5:1

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  39. Content type: Research

    Dietary intervention trials rely on self-reported measures of intake for assessment of energy and macronutrient composition. Dietary fat intake is of particular interest due to strong associations with pathoph...

    Authors: Sally D Poppitt, Paul Kilmartin, Paul Butler and Geraldine F Keogh

    Citation: Lipids in Health and Disease 2005 4:30

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  40. Content type: Research

    13-Methyltetradecanoic acid (13-MTD), an iso-C15 branched- chain saturated fatty acid, has been shown to induce apoptotic cell death of numerous human cancer cells. However, the mechanism for the induction of ...

    Authors: Sawitree Wongtangtintharn, Hirosuke Oku, Hironori Iwasaki, Masashi Inafuku, Takayoshi Toda and Teruyoshi Yanagita

    Citation: Lipids in Health and Disease 2005 4:29

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