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  1. Although the association between the apolipoprotein A5 (APOA5) genetic variants and hypertriglyceridemia has been extensively studied, there have been few studies, particularly in children and adolescents, on the...

    Authors: Wei-fen Zhu, Chun-lin Wang, Li Liang, Zheng Shen, Jun-fen Fu, Pei-ning Liu, Lan-qiu Lv and Yi-min Zhu
    Citation: Lipids in Health and Disease 2014 13:93
    Content type: Research Published on:

  2. The conversions of the n-3 and n-6 fatty acid of plant origin to the C20 and C22 very long chain fatty acids (LCPUFAs) is regulated by several cellular enzymes such as elongases and desaturases.

    Authors: Anna Haug, Nicole F Nyquist, Magny Thomassen, Arne T Høstmark and Tone-Kari Knutsdatter Østbye
    Citation: Lipids in Health and Disease 2014 13:92
    Content type: Research Published on:

  3. Probucol has been shown to prevent cerebral capillary disturbances characterized by blood-to-brain extravasation of plasma derived proteins and neurovascular inflammation in mice maintained on western-styled d...

    Authors: Ryusuke Takechi, Menuka M Pallebage-Gamarallage, Virginie Lam, Corey Giles and John CL Mamo
    Citation: Lipids in Health and Disease 2014 13:91
    Content type: Research Published on:

  4. Persistent immune activation and inflammation are lying behind HIV-infection even in the setting of ART mediated viral suppression. The purpose of this study is to define the in vivo effect of two first-line ART ...

    Authors: Vasiliki D Papakonstantinou, Maria Chini, Nikos Mangafas, George M Stamatakis, Nickolaos Tsogas, Alexandros B Tsoupras, Katherina Psarra, Elizabeth Fragopoulou, Smaragdi Antonopoulou, Panagiotis Gargalianos, Constantinos A Demopoulos and Marios-C Lazanas
    Citation: Lipids in Health and Disease 2014 13:90
    Content type: Research Published on:

  5. Glycosylated hemoglobin A1C (HbA1c) has been widely recognized as a marker for predicting the severity of diabetes mellitus (DM) and several cardiovascular diseases. However, whether HbA1c could predict the se...

    Authors: Li-Feng Hong, Xiao-Lin Li, Yuan-Lin Guo, Song-Hui Luo, Cheng-Gang Zhu, Ping Qing, Rui-Xia Xu, Na-Qiong Wu and Jian-Jun Li
    Citation: Lipids in Health and Disease 2014 13:89
    Content type: Research Published on:

  6. Ivy gourd (Coccinia grandis L. Voigt) is a tropical plant widely distributed throughout Asia, Africa, and the Pacific Islands. The anti-obesity property of this plant has been claimed but still remains to be scie...

    Authors: Ruthaiwan Bunkrongcheap, Nongporn Hutadilok-Towatana, Kusumarn Noipha, Chatchai Wattanapiromsakul, Masashi Inafuku and Hirosuke Oku
    Citation: Lipids in Health and Disease 2014 13:88
    Content type: Research Published on:

  7. The over-all age-adjusted prevalence of diabetes mellitus type 2 (DMT2) in Saudi Arabia is unprecedented at 31%. Aggressive measures should be done to curb down increasing incidence. In this prospective 6-mont...

    Authors: Nasser M Al-Daghri, Hanan Alfawaz, Naji J Aljohani, Yousef Al-Saleh, Kaiser Wani, Abdullah M Alnaami, Mohammad Alharbi and Sudhesh Kumar
    Citation: Lipids in Health and Disease 2014 13:87
    Content type: Research Published on:

  8. Omega-3 (n-3) polyunsaturated fatty acid (PUFA) consumption increases low-density lipoprotein (LDL) cholesterol (C) concentrations and particle size. Studies showed that individuals with large, buoyant LDL par...

    Authors: Catherine Ouellette, Iwona Rudkowska, Simone Lemieux, Benoit Lamarche, Patrick Couture and Marie-Claude Vohl
    Citation: Lipids in Health and Disease 2014 13:86
    Content type: Research Published on:

  9. Studies had investigated the relationships between endothelial lipase (EL) 584C/T polymorphism and high density lipoprotein cholesterol (HDL-C) level and coronary heart disease (CHD), but the results were cont...

    Authors: Gaojun Cai, Zhiying Huang, Bifeng Zhang, Weijin Weng and Ganwei Shi
    Citation: Lipids in Health and Disease 2014 13:85
    Content type: Research Published on:

  10. Endothelial cell activation and dysfunction are the foundation of atherosclerosis, including coronary artery disease (CAD). Endothelial cell activation is mediated by the level of gene transcription. Early gro...

    Authors: Xia Li, Yi-Tong Ma, Xiang Xie, Yi-Ning Yang, Xiang Ma, Ying-Ying Zheng, Shuo Pan, Fen Liu and Bang-Dang Chen
    Citation: Lipids in Health and Disease 2014 13:84
    Content type: Research Published on:

  12. Herring roe is an underutilized source of n-3 polyunsaturated fatty acids (PUFAs) for human consumption with high phospholipid (PL) content. Studies have shown that PL may improve bioavailability of n-3 PUFAs....

    Authors: Bodil Bjørndal, Elin Strand, Jennifer Gjerde, Pavol Bohov, Asbjørn Svardal, Bernd WK Diehl, Sheila M Innis, Alvin Berger and Rolf K Berge
    Citation: Lipids in Health and Disease 2014 13:82
    Content type: Research Published on:

  13. The apoB/apoA1 ratio has been reported to be associated with the metabolic syndrome (MetS), and it may be a more convenient biomarker in MetS predicting. However, whether apoB/apoA1 ratio is a better indicator...

    Authors: Fangyuan Jing, Yingying Mao, Jing Guo, Zhenyu Zhang, Yingjun Li, Zhenhua Ye, Ye Ding, Jianbing Wang, Mingjuan Jin and Kun Chen
    Citation: Lipids in Health and Disease 2014 13:81
    Content type: Research Published on:

  14. Atherosclerosis is the leading etiologic factor of Atherosclerotic Cerebral Infarction (ACI). Previous studies have shown that thrombin activatable fibrinolysis inhibitor (TAFI) may play an important role in t...

    Authors: You Li, Zhiliang Zeng, Jianghao Zhao, Guoda Ma, Lili Cui, Hua Tao, Zhijun Lin, Yanyan Chen, Bin Zhao, Yusen Chen and Keshen Li
    Citation: Lipids in Health and Disease 2014 13:80
    Content type: Research Published on:

  16. Polyunsaturated fatty acids (PUFAs) may protect against metabolic diseases. Although the benefits of the n-3 family of PUFA have been well investigated in nonalcoholic steatohepatitis (NASH), little is known a...

    Authors: Hitoshi Maruyama, Masanori Takahashi, Tadashi Sekimoto, Taro Shimada and Osamu Yokosuka
    Citation: Lipids in Health and Disease 2014 13:78
    Content type: Research Published on:

  17. Depression and high-fat diet are both known as independent risk factors for atherosclerosis and other cardiovascular diseases, suggesting the interaction of psychological and physiological factors in the devel...

    Authors: Shuling Wang, Gao Xiaoling, Li Pingting, Liu Shuqiang and Zeng Yuaner
    Citation: Lipids in Health and Disease 2014 13:77
    Content type: Research Published on:

  18. Many health effects of oils rich in oleic acid (OA, 18:1 n9) seem to be opposite those of arachidonic acid (AA, 20:4 n6), i.e. concerning cardiovascular risk. In recent studies in humans and in the rat we obse...

    Authors: Arne Torbjørn Høstmark and Anna Haug
    Citation: Lipids in Health and Disease 2014 13:76
    Content type: Research Published on:

  19. Previous studies indicated that hyperlipidemia was associated with retinitis pigmentosa (RP). We aimed to identify the mutations in the C5L2 gene which was reported to be associated with hyperlipidemia in a Ch...

    Authors: Ling-hui Qu, Xin Jin, Liang-mao Li, Shi-ying Li and Han-ping Xie
    Citation: Lipids in Health and Disease 2014 13:75
    Content type: Research Published on:

    The Erratum to this article has been published in Lipids in Health and Disease 2014 13:110

  20. Polymorphisms in the LPA gene were associated with coronary artery disease (CAD). However, there are differences in the allelic frequencies, Lp(a) levels, and significant association with CAD according to ethnic ...

    Authors: Paulo CJL Santos, Carolina T Bueno, Pedro A Lemos, José E Krieger and Alexandre C Pereira
    Citation: Lipids in Health and Disease 2014 13:74
    Content type: Research Published on:

  21. The role of triglyceride (TG) in predicting the outcomes in diabetic patients with coronary artery disease (CAD) has not been well investigated.

    Authors: Xiao-Lin Li, Li-Feng Hong, Song-Hui Luo, Yuan-Lin Guo, Cheng-Gang Zhu, Jing Sun, Qian Dong, Ping Qing, Rui-Xia Xu, Jun Liu, Sha Li, Na-Qiong Wu, Geng Liu and Jian-Jun Li
    Citation: Lipids in Health and Disease 2014 13:73
    Content type: Research Published on:

  22. The efficacy and safety of plant stanols added to food products as serum cholesterol lowering agents have been demonstrated convincingly, but their effects on cholesterol metabolism and on serum non-cholestero...

    Authors: Maarit Hallikainen, Piia Simonen and Helena Gylling
    Citation: Lipids in Health and Disease 2014 13:72
    Content type: Research Published on:

  24. Clusterin (CLU) /Apolipoprotein J is a protein biosensor of oxidative stress and inflammation, which is upregulated in many pathological processes including atherosclerosis. Previous studies have shown that in...

    Authors: Amalia E Yanni, George Agrogiannis, Christos Gkekas and Despina Perrea
    Citation: Lipids in Health and Disease 2014 13:70
    Content type: Research Published on:

  25. Non-alcoholic fatty liver disease (NAFLD) is a continuum of diseases that include simple steatosis and non-alcoholic steatohepatitis (NASH) ultimately leading to cirrhosis, hepatocellular carcinoma and end sta...

    Authors: Irina Voloshin, Michal Hahn-Obercyger, Sarit Anavi and Oren Tirosh
    Citation: Lipids in Health and Disease 2014 13:69
    Content type: Research Published on:

  27. Inflammation and endothelial dysfunction is implicated in the atherosclerosis initiation and progression in the setting of hyperlipidemia. Colchicine is a potent anti-inflammatory agent and whether colchicine ...

    Authors: Congwu Huang, Chuan Cen, ChengXu Wang, Haiyong Zhan and Xin Ding
    Citation: Lipids in Health and Disease 2014 13:67
    Content type: Research Published on:

  28. γ-tocotrienol (GT3), an analogue of vitamin E, has gained increasing scientific interest recently as it provides significant health benefits. It has been shown that emulsified GT3, after subcutaneous administr...

    Authors: Lili Deng, Ying Peng, Yu Wu, Meilin Yang, Yuedi Ding, Quancheng Chen and Qiang Fu
    Citation: Lipids in Health and Disease 2014 13:66
    Content type: Research Published on:

  29. Heterozygous Familial hypercholesterolemia (FH) is a common autosomal dominant disorder resulting in in very high blood cholesterol levels and premature cardiovascular disease (CVD). However, there is a wide v...

    Authors: Matthew D Allard, Ramesh Saeedi, Masoud Yousefi and Jiri Frohlich
    Citation: Lipids in Health and Disease 2014 13:65
    Content type: Research Published on:

  30. Numerous clinical studies have reported that ingestion of chocolate has reduced risk of metabolic syndrome. In order to elucidate the mechanism, we evaluated the influence of flavan-3-ols derived from cocoa po...

    Authors: Naoki Watanabe, Kodai Inagawa, Masahiro Shibata and Naomi Osakabe
    Citation: Lipids in Health and Disease 2014 13:64
    Content type: Research Published on:

  31. Atherosclerosis is the most common pathologic process underlying cardiovascular disease. Both flaxseed oil (FO) and astaxanthin (ASX) are believed to benefit cardiovascular system. The combined effect of FO an...

    Authors: Jiqu Xu, Hui Gao, Li Zhang, Chang Chen, Wei Yang, Qianchun Deng, Qingde Huang and Fenghong Huang
    Citation: Lipids in Health and Disease 2014 13:63
    Content type: Research Published on:

  32. This study aimed to determine early postoperative changes of plasma polyunsaturated fatty acids (PUFAs) following laparoscopic sleeve gastrectomy (LSG).

    Authors: Mutay Aslan, Ibrahim Aslan, Filiz Özcan, Ramazan Eryılmaz, Cemal Ozben Ensari and Tuna Bilecik
    Citation: Lipids in Health and Disease 2014 13:62
    Content type: Research Published on:

  33. Fatty acid-binding protein 2 (FABP2) is an intracellular protein expressed exclusively in the enterocytes of proximal small intestine. FABP2 has a high affinity for saturated and unsaturated long-chain fatty acid...

    Authors: Khalid Khalaf Alharbi, Imran Ali Khan, Mohammad D Bazzi, Nasser M Al-Daghri, Tarique N Hasan, May Salem Alnbaheen, Fawiziah Khalaf Alharbi, Yazeed A Al-Sheikh, Rabbani Syed and Mourad AM Aboul-Soud
    Citation: Lipids in Health and Disease 2014 13:61
    Content type: Research Published on:

  34. The goal of the study is to investigate the association between the APOA5 polymorphisms and haplotypes with Arterial Hypertension (AHT) in Moroccan patients.

    Authors: Sanaa Ouatou, Maria Ajjemami, Hicham Charoute, Hajar Sefri, Noreddine Ghalim, Houria Rhaissi, Houda Benrahma, Abdelhamid Barakat and Hassan Rouba
    Citation: Lipids in Health and Disease 2014 13:60
    Content type: Research Published on:

  35. Statin therapy results in regression and stabilization of coronary artery plaques, and reduces the incidence of coronary artery disease. However, statin therapy does not effectively halt the accumulation of ne...

    Authors: Tsuyoshi Nozue, Shingo Yamamoto, Shinichi Tohyama, Kazuki Fukui, Shigeo Umezawa, Yuko Onishi, Tomoyuki Kunishima, Akira Sato, Toshihiro Nozato, Shogo Miyake, Youichi Takeyama, Yoshihiro Morino, Takao Yamauchi, Toshiya Muramatsu, Kiyoshi Hibi, Mitsuyasu Terashima…
    Citation: Lipids in Health and Disease 2014 13:59
    Content type: Research Published on:

  36. This study was performed to understand the possible therapeutic activity of Terminalia paniculata ethanolic extract (TPEE) on non alcoholic fatty liver in rats fed with high fat diet.

    Authors: Mopuri Ramgopal, Banavathy S Kruthika, Damineni Surekha and Balaji Meriga
    Citation: Lipids in Health and Disease 2014 13:58
    Content type: Research Published on:

  37. Metabolic syndrome is now widely appreciated as a cluster of metabolic abnormalities such as visceral obesity, hypertension, hyperglycemia and dyslipidemia. To date, incidence of metabolic syndrome is continuo...

    Authors: Hiroko Inoue, Ryosuke Sasaki, Izumi Aiso and Toshiko Kuwano
    Citation: Lipids in Health and Disease 2014 13:57
    Content type: Research Published on:

  38. In castration-resistant prostate cancer (CRPC), recent evidence has demonstrated the persistence of the intratumoral androgens. The multi-step androgen synthesis pathway originates from cholesterol, which can ...

    Authors: Jenny Hanbi Kim, Michael E Cox and Kishor M Wasan
    Citation: Lipids in Health and Disease 2014 13:56
    Content type: Research Published on:

  40. Dyslipidemia and abnormal phospholipid metabolism are frequent in uremic patients and increase their risk of cardiovascular disease (CVD): ω-3 polyunsaturated fatty acids (PUFAs) may reduce this risk in the ge...

    Authors: Mariarita Dessì, Annalisa Noce, Pierfrancesco Bertucci, Gianluca Noce, Stefano Rizza, Alessandro De Stefano, Simone Manca di Villahermosa, Sergio Bernardini, Antonino De Lorenzo and Nicola Di Daniele
    Citation: Lipids in Health and Disease 2014 13:54
    Content type: Research Published on:

  41. Bone marrow mesenchymal stem cells (BM-MSCs) are capable of differentiating into endothelial cells in vitro and acquire major characteristics of mature endothelial-like expression of vWF and CD31. SFAs and lip...

    Authors: Yuanshan Lu, Zihui Zhou, Jie Tao, Bang Dou, Mingjie Gao and Yue Liu
    Citation: Lipids in Health and Disease 2014 13:53
    Content type: Research Published on:

  42. Alterations or mutations in the lipoprotein lipase (LPL) gene contribute to severe hypertriglyceridemia (HTG). This study reported on two patients in a Chinese family with LPL gene mutations and severe HTG and...

    Authors: Tan-Zhou Chen, Sai-Li Xie, Rong Jin and Zhi-Ming Huang
    Citation: Lipids in Health and Disease 2014 13:52
    Content type: Research Published on:

  43. Genome-wide association studies found low plasma levels of 25-hydroxyvitamin D and vitamin D receptor (VDR) polymorphisms associated with a higher prevalence of pathological changes in the intestine such as ch...

    Authors: Hagen Kühne, Alexandra Schutkowski, Susann Weinholz, Christina Cordes, Angelika Schierhorn, Kristin Schulz, Bettina König and Gabriele I Stangl
    Citation: Lipids in Health and Disease 2014 13:51
    Content type: Research Published on:

  44. Apolipoprotein M (apoM), as a novel apolipoprotein which is mainly expressed in liver and kidney tissues, is associated with development and progression of atherosclerosis and diabetes. Our group have recently...

    Authors: Jia-Yi Zhao, Yan-Wei Hu, Shu-Fen Li, Ya-Rong Hu, Xin Ma, Shao-Guo Wu, Yan-Chao Wang, Ji-Juan Gao, Yan-Hua Sha, Lei Zheng and Qian Wang
    Citation: Lipids in Health and Disease 2014 13:50
    Content type: Research Published on:

  45. Contradictory data on consequences of prolonged high-fat diet requires a detailed study of the influence of nutritional high-fat load mechanisms on the peculiarity of lipid metabolism in blood and liver. The p...

    Authors: Natalia V Zhukova, Tatyana P Novgorodtseva and Yulia K Denisenko
    Citation: Lipids in Health and Disease 2014 13:49
    Content type: Research Published on:

  46. Oxidized phosphatidylcholines (oxPC) and lysophosphatidylcholine (lysoPC) generated during the formation of oxidized low-density lipoprotein (oxLDL) are involved in atherosclerotic lesion development. We inves...

    Authors: Naoko Sasabe, Yuka Keyamura, Takashi Obama, Nozomi Inoue, Yukihiro Masuko, Yu Igarashi, Toshihiro Aiuchi, Rina Kato, Tomohiro Yamaguchi, Hiroshi Kuwata, Sanju Iwamoto, Akira Miyazaki, Shuntaro Hara, Tomohiro Yoshikawa and Hiroyuki Itabe
    Citation: Lipids in Health and Disease 2014 13:48
    Content type: Research Published on:

  47. Studies investigating the association between the apolipoprotein E (APOE) gene polymorphism and the risk of intracerebral hemorrhage (ICH) have reported conflicting results. We here performed a meta-analysis b...

    Authors: Rongjun Zhang, Xiaofeng Wang, Zongchun Tang, Jianxin Liu, Shuzhen Yang, Youbing Zhang, Yijun Wei, Wenyin Luo, Jun Wang, Jialong Li, Bobo Chen and Kunhu Zhang
    Citation: Lipids in Health and Disease 2014 13:47
    Content type: Research Published on:

  48. Recently, it has been found that Fructus Schisandra Chinensis (FSC), a Chinese herbal medicine, and its related compounds have a profound impact on lipid metabolism process. FSC can be divided into two parts, i.e...

    Authors: Nan Sun, Si-Yuan Pan, Yi Zhang, Xiao-Yan Wang, Pei-Li Zhu, Zhu-Sheng Chu, Zhi-Ling Yu, Shu-Feng Zhou and Kam-Ming Ko
    Citation: Lipids in Health and Disease 2014 13:46
    Content type: Research Published on:

  49. Single-nucleotide polymorphisms (SNPs) around the apolipoprotein A5 gene (APOA5) have pleiotropic effects on the levels of triglyceride (TG) and high-density lipoprotein cholesterol (HDL-C). APOA5 SNPs have also ...

    Authors: Seongwon Cha, Hyunjoo Yu, Ah Yeon Park and Kwang Hoon Song
    Citation: Lipids in Health and Disease 2014 13:45
    Content type: Research Published on:

  50. Although several studies have reported an association between mental disorders and serum levels of brain-derived neurotrophic factor (BDNF), this association is still poorly understood. The study of factors as...

    Authors: Charles Francisco Ferreira, Juliana Rombaldi Bernardi, Vera Lúcia Bosa, Ilaine Schuch, Marcelo Zubaran Goldani, Flávio Kapczinski, Giovanni Abrahão Salum, Carla Dalmaz, Gisele Gus Manfro and Patrícia Pelufo Silveira
    Citation: Lipids in Health and Disease 2014 13:44
    Content type: Short report Published on:
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Lipids in Health and Disease

ISSN: 1476-511X