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  1. Obesity, type 2 diabetes and hyperlipidemia frequently coexist and are associated with significantly increased morbidity and mortality. Consumption of refined carbohydrate and particularly fructose has increas...

    Authors: Danshan Huang, Tania Dhawan, Stephen Young, William H Yong, Laszlo G Boros and Anthony P Heaney
    Citation: Lipids in Health and Disease 2011 10:20
  2. Modification of fatty acids (FA) composition in erythrocytes lipids as an early indicator of the development of arterial hypertension (AH) and lipid disorders.

    Authors: Tatyana P Novgorodtseva, Tatyana A Kantur, Yulia K Karaman, Marina V Antonyuk and Natalia V Zhukova
    Citation: Lipids in Health and Disease 2011 10:18
  3. To investigate the effect of triglyceride (TG) integrates with plasma major components of apolipoproteins in HDL subclasses distribution and further elicited the TG-apolipoproteins (apos) interaction in the pr...

    Authors: Li Tian, Yanhua Xu, Mingde Fu, Tao Peng, Yinghui Liu and Shiyin Long
    Citation: Lipids in Health and Disease 2011 10:17
  4. Eicosanoids are major players in the pathogenesis of several common diseases, with either overproduction or imbalance (e.g. between thromboxanes and prostacyclins) often leading to worsening of disease symptoms. ...

    Authors: Olav A Christophersen and Anna Haug
    Citation: Lipids in Health and Disease 2011 10:16
  5. Trans fat are not desirable in many aspects on health maintenance. Low trans structured fats have been reported to be relatively more safe than trans fats.

    Authors: Yun-Young Cho, Eun-Young Kwon, Hye-Jin Kim, Seon-Min Jeon, Ki-Teak Lee and Myung-Sook Choi
    Citation: Lipids in Health and Disease 2011 10:15
  6. Several genetic variants in the ATP-binding cassette transporter A1 (ABCA1) gene have associated with modifications of serum high-density lipoprotein cholesterol (HDL-C) levels and the susceptibility for coron...

    Authors: Xiao-Li Cao, Rui-Xing Yin, Dong-Feng Wu, Lin Miao, Lynn Htet Htet Aung, Xi-Jiang Hu, Qing Li, Ting-Ting Yan, Wei-Xiong Lin and Shang-Ling Pan
    Citation: Lipids in Health and Disease 2011 10:14
  7. Lipoprotein-associated phospholipase A2 (Lp-PLA2) is a recently identified and potentially useful plasma biomarker for cardiovascular and atherosclerotic diseases. However, the correlation between the Lp-PLA2 act...

    Authors: Hui-ping Gong, Yi-meng Du, Li-na Zhong, Zhao-qiang Dong, Xin Wang, Yong-jun Mao and Qing-hua Lu
    Citation: Lipids in Health and Disease 2011 10:13
  8. Visceral Fat Area (VFA) is an independent predictor of coronary disease. While low density lipoprotein cholesterol (LDL-C) is used to determine risk and guide therapy, its accuracy fails in obese patients who ...

    Authors: Michel R Hoenig, Gary Cowin, Raymond Buckley, Christine McHenery and Allan Coulthard
    Citation: Lipids in Health and Disease 2011 10:12
  9. Adiponectin is the most abundant plasma protein synthesized for the most part in adipose tissue, and it is an insulin-sensitive hormone, playing a central role in glucose and lipid metabolism. In addition, it ...

    Authors: Cristiane de Oliveira, Ana BM de Mattos, Carolina Biz, Lila M Oyama, Eliane B Ribeiro and Cláudia Maria Oller do Nascimento
    Citation: Lipids in Health and Disease 2011 10:11
  10. n-3 and n-6 polyunsaturated fatty acids (PUFAs) are the two major classes of PUFAs encountered in the diet, and both classes of fatty acids are required for normal human health. Moreover, PUFAs have effects on di...

    Authors: Maria Notarnicola, Caterina Messa, Maria G Refolo, Valeria Tutino, Angelica Miccolis and Maria G Caruso
    Citation: Lipids in Health and Disease 2011 10:10
  11. The Roma (Gypsies) are a transnational minority, founder population characterized by unique genetic background modeled by culturally determined endogamy. The present study explores whether the widely found car...

    Authors: Hrvojka Marija Zeljko, Tatjana Škarić-Jurić, Nina Smolej Narančić, Željka Tomas, Ana Barešić, Marijana Peričić Salihović, Boris Starčević and Branka Janićijević
    Citation: Lipids in Health and Disease 2011 10:9
  12. Statins are first-line pharmacotherapeutic agents for hypercholesterolemia treatment in humans. However the effects of statins on atherosclerosis in mouse models are very paradoxical. In this work, we wanted t...

    Authors: Guohua Song, Jia Liu, Zhenmei Zhao, Yang Yu, Hua Tian, Shutong Yao, Guoli Li and Shucun Qin
    Citation: Lipids in Health and Disease 2011 10:8
  13. Sphingomyelin synthase 2 (SMS2) contributes to de novo sphingomyelin (SM) biosynthesis. Its activity is related to SM levels in the plasma and the cell membrane. In this study, we investigated the possibility ...

    Authors: Xiaogang Wang, Jibin Dong, Yarui Zhao, Yue Li and Manping Wu
    Citation: Lipids in Health and Disease 2011 10:7
  14. Obesity became major health problem in the world, the objective of this work was to examine the effect of high sucrose and high fat diet to induce obesity on antioxidant defense system, biochemical changes in ...

    Authors: Kamal A Amin, Hamdy H Kamel and Mohamed A Abd Eltawab
    Citation: Lipids in Health and Disease 2011 10:6
  15. Proprotein convertase subtilisin-like kexin type 9 (PCSK9) plays a key role in regulating plasma low-density lipoprotein cholesterol (LDL-C) levels. However, the association of E670G (rs505151) polymorphism in...

    Authors: Lynn Htet Htet Aung, Rui-Xing Yin, Lin Miao, Xi-Jiang Hu, Ting-Ting Yan, Xiao-Li Cao, Dong-Feng Wu, Qing Li, Shang-Ling Pan and Jin-Zhen Wu
    Citation: Lipids in Health and Disease 2011 10:5
  16. The presence of chicken group-IIA PLA2 (ChPLA2-IIA) in the intestinal secretion suggests that this enzyme plays an important role in systemic bactericidal defence. We have analyzed the bactericidal activity of...

    Authors: Aida Karray, Yassine Ben Ali, Youssef Gargouri and Sofiane Bezzine
    Citation: Lipids in Health and Disease 2011 10:4
  17. Metabolic syndrome is a disease that today affects millions of people around the world. Therefore, it is of great interest to implement more effective procedures for preventing and treating this disease. In se...

    Authors: Ana C Ghezzi, Lucieli T Cambri, Carla Ribeiro, José D Botezelli and Maria AR Mello
    Citation: Lipids in Health and Disease 2011 10:3
  18. Inflammation process plays an important role in the development of atherosclerosis. Hypercholesterolemia is one of the major risk factors for atherosclerosis. The present study aimed to evaluate the effect of ...

    Authors: Adel A Amran, Zaiton Zakaria, Faizah Othman, Srijit Das, Hesham M Al-Mekhlafi and Nor-Anita MM Nordin
    Citation: Lipids in Health and Disease 2011 10:2
  19. Oxidized low-density lipoprotein (oxLDL) uptake by macrophages plays an important role in foam cell formation. It has been suggested the presence of heterogeneous subsets of macrophage, such as M1 and M2, in h...

    Authors: Kuniaki Hirose, Kazuhisa Iwabuchi, Kazunori Shimada, Takashi Kiyanagi, Chihiro Iwahara, Hitoshi Nakayama and Hiroyuki Daida
    Citation: Lipids in Health and Disease 2011 10:1
  20. To report changes in body weight, total and central fat mass, metabolic, hormonal and inflammatory parameters in overweight people who participated in a six months weight loss intervention associating diet man...

    Authors: Frédéric Dutheil, Bruno Lesourd, Daniel Courteix, Robert Chapier, Eric Doré and Gérard Lac
    Citation: Lipids in Health and Disease 2010 9:148
  21. Oxidized low-density lipoprotein (LDL) may act as an atheroprotective (anti-atherosclerotic) agent under some conditions. While the α1-antitrypsin (AT)-LDL complex is considered a type of oxidized LDL, its cli...

    Authors: Kazuhiko Kotani, Toshiyuki Yamada and Nobuyuki Taniguchi
    Citation: Lipids in Health and Disease 2010 9:147
  22. Abnormalities in lipid metabolism and transport are hallmarks in analbuminemic Nagase rats (NAR) and humans. Triglyceridemia is nearly 3- to 5-fold higher in female NAR than in control Sprague-Dawley rats (SDR...

    Authors: Tiago R Figueira, Aníbal E Vercesi and Helena CF Oliveira
    Citation: Lipids in Health and Disease 2010 9:146
  23. The association of peroxisome proliferator-activated receptor delta (PPARD) +294T > C polymorphism and serum lipid levels is inconsistent in several previous studies. Bai Ku Yao is an isolated subgroup of the ...

    Authors: Lin Miao, Rui-Xing Yin, Dong-Feng Wu, Xiao-Li Cao, Qing Li, Xi-Jiang Hu, Ting-Ting Yan, Lynn Htet Htet Aung, De-Zhai Yang and Wei-Xiong Lin
    Citation: Lipids in Health and Disease 2010 9:145
  24. Type 2 diabetes is associated with significant cardiovascular morbidity and mortality. Although low-density lipoprotein cholesterol levels may be normal in patients with type 2 diabetes, insulin resistance dri...

    Authors: Krishnaswami Vijayaraghavan
    Citation: Lipids in Health and Disease 2010 9:144
  25. Inflammation has been implicated in cardiovascular disease, and the important role of proteasomes in the development of inflammation and other macrophage functions has been demonstrated. Tocotrienols are poten...

    Authors: Asaf A Qureshi, Julia C Reis, Christopher J Papasian, David C Morrison and Nilofer Qureshi
    Citation: Lipids in Health and Disease 2010 9:143
  26. Statins induces cell cycle arrest, apoptosis, reduction of angiogenic factors, inhibition of the endothelial growth factor, impairing tissue adhesion and attenuation of the resistance mechanisms. The aim of th...

    Authors: Giovani M Favero, Michel F Otuki, Karen A Oliveira, Milton S Bohatch Jr, Primavera Borelli, Francisco E Barros, Durvanei A Maria, Daniel Fernandes and Sergio P Bydlowski
    Citation: Lipids in Health and Disease 2010 9:142
  27. Because abdominal obesity is predisposed to various metabolic disorders, it is of major importance to assess and track the changes with time of this specific fat mass. The main issue for clinicians or research...

    Authors: Maude Gerbaix, Lore Metz, Emeline Ringot and Daniel Courteix
    Citation: Lipids in Health and Disease 2010 9:140
  28. The association of rs1044925 polymorphism in the acyl-CoA:cholesterol acyltransferase-1 (ACAT-1) gene and serum lipid profiles is not well known in different ethnic groups. Bai Ku Yao is a special subgroup of ...

    Authors: Dong-Feng Wu, Rui-Xing Yin, Lynn Htet Htet Aung, Xi-Jiang Hu, Xiao-Li Cao, Lin Miao, Qing Li, Ting-Ting Yan, Jin-Zhen Wu and Shang-Ling Pan
    Citation: Lipids in Health and Disease 2010 9:139
  29. The aim of the present study was to examine how lipid profiles are associated with insulin resistance in Japanese community-dwelling adults.

    Authors: Ryuichi Kawamoto, Yasuharu Tabara, Katsuhiko Kohara, Tetsuro Miki, Tomo Kusunoki, Shuzo Takayama, Masanori Abe, Tateaki Katoh and Nobuyuki Ohtsuka
    Citation: Lipids in Health and Disease 2010 9:138
  30. Rapeseed oil is the principal dietary source of monounsaturated and n-3 polyunsaturated fatty acids in the Northern Europe. However, the effect of rapeseed oil on the markers of subclinical atherosclerosis is ...

    Authors: Ari Palomäki, Hanna Pohjantähti-Maaroos, Marja Wallenius, Päivi Kankkunen, Heikki Aro, Sari Husgafvel, Juha-Matti Pihlava and Kalevi Oksanen
    Citation: Lipids in Health and Disease 2010 9:137
  31. Some patients administered cholesterol-lowering therapies may experience an increase in the proportion of small LDL particles, which may be misinterpreted as a worsening of atherosclerotic coronary heart disea...

    Authors: Harold Bays, Scott Conard, Lawrence A Leiter, Steven Bird, Erin Jensen, Mary E Hanson, Arvind Shah and Andrew M Tershakovec
    Citation: Lipids in Health and Disease 2010 9:136
  32. PUFAs are potent inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, an enzyme catalyzing the conversion of HMGCoA to mevalonate, the rate limiting step in cholesterol biosynthesis. Statin...

    Authors: Maria Notarnicola, Caterina Messa, Maria G Refolo, Valeria Tutino, Angelica Miccolis and Maria G Caruso
    Citation: Lipids in Health and Disease 2010 9:135
  33. Kurozu concentrated liquid (KCL) is used as a health-promoting supplement for the treatment of disorders such as cancer, hyperlipidemia, and hypertension in Japan. We investigated the possible anti-obesity eff...

    Authors: Li-Tao Tong, Yoshinori Katakura, Sayaka Kawamura, Sanae Baba, Yasutake Tanaka, Miyako Udono, Yoshie Kondo, Kumi Nakamura, Katsumi Imaizumi and Masao Sato
    Citation: Lipids in Health and Disease 2010 9:134
  34. Despite significant improvements in the treatment of coronary heart disease (CHD), it is still a major cause of mortality and morbidity among the Iranian population. Epidemiological studies have documented tha...

    Authors: Teymoor Yary, Kourosh Soleimannejad, Firdaus Abd Rahim, Mirnalini Kandiah, Sanaz Aazami, Seyedehozma Jafar Poor, Wong Teck Wee and Golnaz Aazami
    Citation: Lipids in Health and Disease 2010 9:133
  35. 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) catalyzes the conversion of inactive glucocorticoids to active glucocorticoids and plays an important role in the development of obesity and metabolic syndrom...

    Authors: Sakamuri SS Vara Prasad, Anamthathmakula Prashanth, Chodavarapu Pavan Kumar, Sirisha J Reddy, Nappan V Giridharan and Ayyalasomayajula Vajreswari
    Citation: Lipids in Health and Disease 2010 9:132
  36. It is designed to investigate the effects of combination therapy of allicin and fenofibrate on the endothelial and liver functions in rats with hyperlipidemia.

    Authors: Weihong Li, Daxin Wang, Guohua Song, Chunxia Zuo, Xianfu Qiao and Shucun Qin
    Citation: Lipids in Health and Disease 2010 9:131
  37. The high incidence of insulin resistance and the metabolic syndrome in South Asians remains unexplained. I propose that a defect in the activity of Δ6 and Δ5 desaturases and consequent low plasma and tissue conce...

    Authors: Undurti N Das
    Citation: Lipids in Health and Disease 2010 9:130
  38. Dysregulated inflammation in cystic fibrosis (CF) is attributed to an altered production of inflammatory mediators derived from polyunsaturated lipids. In comparison to the arachidonic acid (AA) cascade, littl...

    Authors: Elena Bravo, Mariarosaria Napolitano, Sara Benedetti Valentini and Serena Quattrucci
    Citation: Lipids in Health and Disease 2010 9:129
  39. Cardiovascular diseases (CVD) are the main cause of death and disability in developed countries. In most cases, the progress of CVD is influenced by environmental factors and multifactorial inheritance. The pu...

    Authors: Rafael O Alvim, Silvia RS Freitas, Noely E Ferreira, Paulo CJL Santos, Roberto S Cunha, José G Mill, José E Krieger and Alexandre C Pereira
    Citation: Lipids in Health and Disease 2010 9:128
  40. This post-hoc analysis compared the lipid-altering efficacy of Ezetimibe/Simvastatin 10/20 mg (EZ/Simva) versus Rosuvastatin 10 mg (Rosuva) in patients stratified by statin potency/dose prior to randomization.

    Authors: Margus Viigimaa, Helena Vaverkova, Michel Farnier, Maurizio Averna, Luc Missault, Mary E Hanson, Qian Dong, Arvind Shah and Philippe Brudi
    Citation: Lipids in Health and Disease 2010 9:127
  41. Conjugated linoleic acids (CLA) are a group of positional and geometric isomers of linoleic acid with proven beneficial influence on health. They show e.g. anticarcinogenic, antiobesity, and antiatherogenic ef...

    Authors: Agnieszka Białek, Andrzej Tokarz, Agnieszka Dudek, Weronika Kazimierska and Wojciech Bielecki
    Citation: Lipids in Health and Disease 2010 9:126
  42. Sleep deprivation has been shown to increase inflammatory markers in rat sera and peripheral blood mononuclear cells. Inflammation is a condition associated with pathologies such as obesity, cancer, and cardio...

    Authors: José C Rosa Neto, Fábio S Lira, Daniel P Venancio, Cláudio A Cunha, Lila M Oyama, Gustavo D Pimentel, Sérgio Tufik, Cláudia M Oller do Nascimento, Ronaldo VT Santos and Marco T de Mello
    Citation: Lipids in Health and Disease 2010 9:125
  43. Heme oxygenase-1 (HO-1), the rate-limiting enzyme in heme catabolism, has been reported to have potential antioxidant properties. However, the role of HO-1 on hepatocyte apoptosis remains unclear. We aim to el...

    Authors: YueMin Nan, RongQi Wang, SuXian Zhao, Fang Han, Wen Juan Wu, LingBo Kong, Na Fu, Li Kong and Jun Yu
    Citation: Lipids in Health and Disease 2010 9:124
  44. The association of methylenetetrahydrofolate reductase (MTHFR) gene polymorphism and serum lipid profiles is still controversial in diverse ethnics. Bai Ku Yao is an isolated subgroup of the Yao minority in Ch...

    Authors: Lin Zhang, Rui-Xing Yin, Wan-Ying Liu, Lin Miao, Dong-Feng Wu, Lynn Htet Htet Aung, Xi-Jiang Hu, Xiao-Li Cao, Jin-Zhen Wu and Shang-Ling Pan
    Citation: Lipids in Health and Disease 2010 9:123
  45. The association between modulation of detailed lipoprotein profiles and cholesterol ester transfer (CET) activity by peroxisome proliferator-activated receptor (PPAR)-a agonists in patients with coronary arter...

    Authors: Tetsuro Miyazaki, Kazunori Shimada, Katsumi Miyauchi, Atsumi Kume, Kosei Tanimoto, Takashi Kiyanagi, Katsuhiko Sumiyoshi, Makoto Hiki, Hiroshi Mokuno, Shinya Okazaki, Hitoshi Sato, Takeshi Kurata and Hiroyuki Daida
    Citation: Lipids in Health and Disease 2010 9:122
  46. Intermittent hypoxia (IH), a model of sleep apnea, produces weight loss in animals. We hypothesized that changes in brown adipose tissue (BAT) function are involved in such phenomenon. We investigated the effe...

    Authors: Denis Martinez, Cintia Z Fiori, Diego Baronio, Alicia Carissimi, Renata SR Kaminski, Lenise J Kim, Darlan P Rosa and Ângelo Bos
    Citation: Lipids in Health and Disease 2010 9:121
  47. To investigate the effect of oxidized low density lipoprotein receptor-1 (LOX-1) on tubular epithelial-mesenchymal transition (TEMT) induced by oxidized low-density lipoprotein (ox-LDL) and its mechanism.

    Authors: Rui Wang, Guohua Ding, Wei Liang, Cheng Chen and Hongxia Yang
    Citation: Lipids in Health and Disease 2010 9:120
  48. The double-blinded placebo-controlled randomized study has been performed in 51 coronary heart disease (CHD) patients to estimate the effects of time-released garlic powder tablets Allicor on the values of 10-...

    Authors: Igor A Sobenin, Valentin V Pryanishnikov, Lyudmila M Kunnova, Yevgeny A Rabinovich, Danik M Martirosyan and Alexander N Orekhov
    Citation: Lipids in Health and Disease 2010 9:119

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