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  1. It is believed that deposition of amyloid beta (Aβ) in the brain is the central pathological changes of Alzheimer’s disease (AD), which triggers a series of pathological processes. However, the relationship be...

    Authors: Ningwei Hu, Ling Gao, Yu Jiang, Shan Wei, Suhang Shang, Chen Chen, Liangjun Dang, Jin Wang, Kang Huo, Meiying Deng, Jingyi Wang and Qiumin Qu
    Citation: Lipids in Health and Disease 2020 19:8
    Content type: Research Published on:

  2. Atherosclerotic cardiovascular (CV) events commonly occur in individuals with a low CV risk burden. This study evaluated the ability of the triglyceride glucose (TyG) index to predict subclinical coronary arte...

    Authors: Gyung-Min Park, Young-Rak Cho, Ki-Bum Won, Yu Jin Yang, Sangwoo Park, Soe Hee Ann, Yong-Giun Kim, Eun Ji Park, Shin-Jae Kim, Sang-Gon Lee, Dong Hyun Yang, Joon-Won Kang, Tae-Hwan Lim, Hong-Kyu Kim, Jaewon Choe, Seung-Whan Lee…
    Citation: Lipids in Health and Disease 2020 19:7
    Content type: Research Published on:

  3. The HMG-CoA reductase is key enzyme of cholesterol biosynthesis which potentially contributes in management of hypercholesterolemia. The present study was designed to assess the inhibitory effect of phytoconst...

    Authors: Heera Ram, Noopur Jaipal, Jaykaran Charan, Priya Kashyap, Suresh Kumar, Rashmi Tripathi, Bhim Pratap Singh, Chandra Nayaka Siddaiah, Abeer Hashem, Baby Tabassum and Elsayed Fathi Abd_Allah
    Citation: Lipids in Health and Disease 2020 19:6
    Content type: Research Published on:

  4. Real-world evidence of low-density lipoprotein cholesterol (LDL-C) goal attainment rates for Asian patients is deficient. The objective of this study was to assess the status of dyslipidemia management, especi...

    Authors: Ye Seul Yang, Bo Ram Yang, Mi-Sook Kim, Yunji Hwang and Sung Hee Choi
    Citation: Lipids in Health and Disease 2020 19:5
    Content type: Research Published on:

  5. Menopause predisposes individuals to affective disorders, such as depression, which is tightly related to neuroinflammation. While the neuroinflammatory condition has been demonstrated in ovariectomized (OVX) ...

    Authors: Bin Wu, Qingen Song, Yongkang Zhang, Changshui Wang, Mengqi Yang, Jun Zhang, Wenxiu Han and Pei Jiang
    Citation: Lipids in Health and Disease 2020 19:4
    Content type: Research Published on:

  6. Use of ezetimibe on top of statin therapy has been shown to be effective to reduce LDL cholesterol level in hypercholesterolemic patients. However, little is known regarding the individual variety of the effec...

    Authors: Hayato Tada, Hirofumi Okada, Akihiro Nomura, Masayuki Takamura and Masa-aki Kawashiri
    Citation: Lipids in Health and Disease 2020 19:3
    Content type: Research Published on:

  7. Acute pancreatitis is a pregnancy complication potentially lethal for both the mother and fetus, occurring most frequently in the third trimester or early postpartum. Hypertriglyceridemia may be the cause of i...

    Authors: Gheorghe Cruciat, Georgiana Nemeti, Iulian Goidescu, Stefan Anitan and Andreea Florian
    Citation: Lipids in Health and Disease 2020 19:2
    Content type: Review Published on:

  8. The aim of this study was to compare and summarize the lipid-altering effects of combination therapy with ezetimibe and statins (E/S) and a double dose of statin (D/S) monotherapy on patients with hypercholest...

    Authors: Min Yu, Chunshui Liang, Qianran Kong, Yihan Wang and Minmin Li
    Citation: Lipids in Health and Disease 2020 19:1
    Content type: Research Published on:

  9. Cerebrotendinous xanthomatosis (CTX) and Lathosterolosis represent two treatable inherited disorders of cholesterol metabolism that are characterized by the accumulation of cholestanol and lathosterol, respect...

    Authors: Monica Gelzo, Maria Donata Di Taranto, Concetta Sica, Antonio Boscia, Francesco Papagni, Giuliana Fortunato, Gaetano Corso and Antonio Dello Russo
    Citation: Lipids in Health and Disease 2019 18:235
    Content type: Research Published on:

  10. Non-alcoholic fatty liver disease (NAFLD) is one of the most common liver diseases worldwide, although its pathogenesis remains to be elucidated. A recent study revealed that hepatic Niemann-Pick C1-Like 1 (NP...

    Authors: Yu Toyoda, Tappei Takada, Yoshihide Yamanashi and Hiroshi Suzuki
    Citation: Lipids in Health and Disease 2019 18:234
    Content type: Research Published on:

  11. Previous genome-wide association studies have found two single nucleotide polymorphisms (SNP) rs7692387 and rs1842896 located on or near the GUCY1A3 gene were associated with coronary artery disease (CAD). GUCY1A...

    Authors: Jian-li Li, Liu-yu Liu, Dong-dong Jiang, Yi-ying Jiang, Guo-qiu Zhou, Dong-can Mo and Man Luo
    Citation: Lipids in Health and Disease 2019 18:233
    Content type: Research Published on:

  12. Chanarin Dorfman Syndrome (CDS) is a rare autosomal recessive disorder characterized by the multisytemic accumulation of neutral lipids inside the cytoplasmic lipid droplets. This condition is caused by mutati...

    Authors: Ali Haydar Eskiocak, Sara Missaglia, Laura Moro, Murat Durdu and Daniela Tavian
    Citation: Lipids in Health and Disease 2019 18:232
    Content type: Short report Published on:

  13. Considering the crucial role of low-density lipoprotein-cholesterol (LDL-C) concentration in determining cardiovascular risk, the accuracy of LDL-C estimation is essential. To date, various types of formulae h...

    Authors: Azam Karkhaneh, Molood Bagherieh, Solmaz Sadeghi and Asma Kheirollahi
    Citation: Lipids in Health and Disease 2019 18:231
    Content type: Research Published on:

  14. Adipogenesis is the process of adipocytes formation from unspecialized progenitor cells called mesenchymal stromal cells. Numerous mechanisms including epigenetic regulation modulate the correct progress of th...

    Authors: Malgorzata Malodobra-Mazur, Aneta Cierzniak and Tadeusz Dobosz
    Citation: Lipids in Health and Disease 2019 18:230
    Content type: Research Published on:

  15. Hypertension is a highly prevalent disease and the leading cause of chronic kidney disease (CKD). Metabolic syndrome could also be the risk factor for CKD. We sought to study the association between metabolic ...

    Authors: Kun Xie, Liwen Bao, Xiaofei Jiang, Zi Ye, Jianping Bing, Yugang Dong, Danchen Gao, Xiaoping Ji, Tingbo Jiang, Jiehua Li, Yan Li, Suxin Luo, Wei Mao, Daoquan Peng, Peng Qu, Shangming Song…
    Citation: Lipids in Health and Disease 2019 18:229
    Content type: Research Published on:

  16. Influences of atorvastatin on atherosclerosis and glycemic metabolism may be related to its potential impact on circulating adiponectin, an adipocyte that exerts anti-inflammatory, ant-atherosclerotic, and ant...

    Authors: Xiaoyu Liu, Wei Zhang, Ming Zhao, Guowei Jia and Rongguo Sun
    Citation: Lipids in Health and Disease 2019 18:228
    Content type: Review Published on:

  17. Conflicting results on the prognostic value of blood adiponectin level in patients with coronary artery disease (CAD) have been reported. This meta-analysis aimed to investigate the prognostic value of elevate...

    Authors: Lili Yang, Bin Li, Yuan Zhao and Zhengyi Zhang
    Citation: Lipids in Health and Disease 2019 18:227
    Content type: Review Published on:

  18. Endothelial lipase (EL) plays an important role in lipoprotein metabolism and atherosclerosis. To study the functional roles of EL, we recently generated transgenic (Tg) rabbits and reported that increased hep...

    Authors: Chuan Wang, Manabu Niimi, Shuji Kitajima, Fumikazu Matsuhisa, Haizhao Yan, Sijun Dong, Jingyan Liang and Jianglin Fan
    Citation: Lipids in Health and Disease 2019 18:226
    Content type: Research Published on:

  19. Hypocholesterolemia is the most frequently encountered lipid abnormality in sickle cell disease (SCD). We enrolled pediatric patients to determine the relationships between lipid profile and parameters of hemo...

    Authors: Ahmet Yalcinkaya, Selma Unal and Yesim Oztas
    Citation: Lipids in Health and Disease 2019 18:225
    Content type: Research Published on:

  20. APOC3 is important in lipid transport and metabolism with limited studies reporting genetic sequence variations in specific ethnic groups. The present study aimed to analyze the full APOC3 sequence among Kuwaiti ...

    Authors: Zainab H. Malalla, Ahmad E. Al-Serri, Huda M. AlAskar, Wafaa Y. Al-Kandari and Suzanne A. Al-Bustan
    Citation: Lipids in Health and Disease 2019 18:224
    Content type: Research Published on:

  21. Obesity is the most common nutritional disorder worldwide and is associated with dyslipidemia and atherosclerotic cardiovascular disease. The hallmark of dyslipidemia in obesity is low high density lipoprotein...

    Authors: Tianhua Zhang, Jin Chen, Xiaoyu Tang, Qin Luo, Danyan Xu and Bilian Yu
    Citation: Lipids in Health and Disease 2019 18:223
    Content type: Review Published on:

  23. Lipids and adipokines including leptin, resistin and visfatin play various roles in the pathophysiology of Gestational Diabetes Mellitus (GDM). This study was aimed at determining whether serum leptin, resisti...

    Authors: Ahmed Tijani Bawah, Mohammed Mustapha Seini, Albert Abaka-Yawason, Huseini Alidu and Salifu Nanga
    Citation: Lipids in Health and Disease 2019 18:221
    Content type: Research Published on:

  24. Apolipoprotein C3 (apoC3) and apolipoprotein A5 (apoA5), encoded by APOA1/C3/A4/A5 gene cluster, are two critical regulators of plasma triglyceride (TG) metabolism. Deficiency of apoC3 or apoA5 led to significant...

    Authors: Wen Dai, Ziyu Zhang, Chun Yao and Shuiping Zhao
    Citation: Lipids in Health and Disease 2019 18:220
    Content type: Review Published on:

  25. High-density lipoprotein cholesterol (HDL-C) is considered as a protective marker of coronary atherosclerotic disease (CAD). It is still not clear if HDL-C is associated with left ventricular (LV) diastolic fu...

    Authors: Lufan Sun, Xiaorui Liu, Wenna Li and Dalin Jia
    Citation: Lipids in Health and Disease 2019 18:219
    Content type: Research Published on:

  26. The cholesterol gallstones diseases (CGD) is highly correlated with metabolic syndrome and type 2 diabetes. The present study aimed to investigate preventive effects of pioglitazone (PIO), an antidiabetic drug...

    Authors: Tao Han, Yangge Lv, Shijia Wang, Tao Hu, Hao Hong and Zan Fu
    Citation: Lipids in Health and Disease 2019 18:218
    Content type: Research Published on:

  27. Coronary artery disease (CAD) is the leading cause of mortality and morbidity worldwide. Previous studies have shown that complement component 3 (C3) is associated with atherosclerosis and cardiovascular risk ...

    Authors: Gaojun Cai, Li Li, Yifei Chen, Haomin Huang, Lei Yu and Lianhong Xu
    Citation: Lipids in Health and Disease 2019 18:217
    Content type: Research Published on:

  28. There is no randomized clinical trials with recurrence of atherosclerotic cardiovascular disease (ASCVD) as a major outcome with rosuvastatin. In order to analyze potential differences in the clinical response...

    Authors: Sofía Perez-Calahorra, Martin Laclaustra, Victoria Marco-Benedi, Xavier Pinto, Rosa M. Sanchez-Hernandez, Núria Plana, Emilio Ortega, Francisco Fuentes and Fernando Civeira
    Citation: Lipids in Health and Disease 2019 18:216
    Content type: Short report Published on:

  29. Macrophage are specialized cells that contributes to the removal of detrimental contents via phagocytosis. Lipid accumulation in macrophages, whether from phagocytosis of dying cells or from circulating oxidiz...

    Authors: Priscila Calle, Angeles Muñoz, Anna Sola and Georgina Hotter
    Citation: Lipids in Health and Disease 2019 18:215
    Content type: Research Published on:

  30. To study whether minimal doses of arachidonic acid (AA), eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) and lipoxin A4 (LXA4) and brain-derived neurotrophic factor (BDNF), when used in combination ...

    Authors: Siresha Bathina and Undurti N. Das
    Citation: Lipids in Health and Disease 2019 18:214
    Content type: Research Published on:

  31. In developing and developed countries, several versions of safe and shelf-stable Ultra High Temperature, UHT-treated products are manufactured. Terminologies and formulations of UHT-treated tea whitener, milk ...

    Authors: Muhammad Ajmal, Muhammad Nadeem, Muhammad Imran, Zarina Mushtaq, Muhammad Haseeb Ahmad, Muhammad Tayyab, Muhammad Kamran Khan and Nabila Gulzar
    Citation: Lipids in Health and Disease 2019 18:213
    Content type: Research Published on:

  33. Insulin resistance (IR) and lipid peroxidation are accepted as ‘two-hit’ hypothesis of Non-alcoholic fatty liver disease (NAFLD). However, there are few published research on identifying genes which connect li...

    Authors: Ting Li, Hua Yan, Yan Geng, Haitao Shi, Hong Li, Shenhao Wang, Yatao Wang, Jingyuan Xu, Gang Zhao and Xiaolan Lu
    Citation: Lipids in Health and Disease 2019 18:211
    Content type: Research Published on:

  34. It has been confirmed that the triglyceride to high-density lipoprotein cholesterol ratio (THR) is associated with insulin resistance and metabolic syndrome. However, to the best of our knowledge, only a few s...

    Authors: Xin-Ya Dai, Ying-Ying Zheng, Jun-Nan Tang, Xu-Ming Yang, Qian-Qian Guo, Jian-Chao Zhang, Meng-Die Cheng, Feng-Hua Song, Zhi-Yu Liu, Kai Wang, Li-Zhu Jiang, Lei Fan, Xiao-Ting Yue, Yan Bai, Zeng-Lei Zhang, Ru-Jie Zheng…
    Citation: Lipids in Health and Disease 2019 18:210
    Content type: Research Published on:

  35. Consumption of a Western-styled diet enriched in saturated fatty acids (SFA) relative to polyunsaturated fatty acids is positively associated with risk for Alzheimer’s disease. Whilst potential causal mechanis...

    Authors: Susan Galloway, Ryusuke Takechi, Michael Nesbit, Menuka M. Pallebage-Gamarallage, Virginie Lam and John C. L. Mamo
    Citation: Lipids in Health and Disease 2019 18:209
    Content type: Research Published on:

  36. MicroRNAs are short non-coding RNAs that regulate gene expression. The aim of this study was to gain an understanding of the possible role of the miR-106b~ 25 microRNA cluster in regulating atherosclerosis in ...

    Authors: Jonathan Semo, Gil Chernin, Michael Jonas, Sara Shimoni and Jacob George
    Citation: Lipids in Health and Disease 2019 18:208
    Content type: Research Published on:

  37. Endoplasmic reticulum (ER) stress and mitochondrial function affected intramuscular fat accumulation. However, there is no clear evident on the effect of the regulation of ER stress and mitochondrial function ...

    Authors: Xi Cao, Xin-Meng Lu, Xiu Tuo, Jing-Yi Liu, Yi-Chen Zhang, Li-Ni Song, Zhi-Qiang Cheng, Jin-Kui Yang and Zhong Xin
    Citation: Lipids in Health and Disease 2019 18:207
    Content type: Research Published on:

  38. Postprandial high triglyceride (HTG), marking elevated level of remnant cholesterol (RC), is an independent risk factor of coronary heart disease (CHD). The postprandial cut-off points for HTG and high RC (HRC...

    Authors: Jin Xu, Yan-Qiao Chen, Shui-Ping Zhao and Ling Liu
    Citation: Lipids in Health and Disease 2019 18:206
    Content type: Research Published on:

  39. Resistant starch (RS) is a starch that can be fermented by the microbial flora within gut lumen. Insulin resistance (IR) is a pathophysiological condition related to diabetes and obesity. RS could reduce blood...

    Authors: Chenlin Gao, Mingyue Rao, Wei Huang, Qin Wan, Pijun Yan, Yang Long, Man Guo, Youhua Xu and Yong Xu
    Citation: Lipids in Health and Disease 2019 18:205
    Content type: Research Published on:

  41. A healthy gastric mucosal epithelium exhibits tumor-suppressive properties. Gastric epithelial cell dysfunction contributes to gastric cancer development. Oxysterols provided from food or cholesterol oxidation...

    Authors: Wenting Hong, Fenghua Guo, Mingjie Yang, Dongke Xu, Ziyan Zhuang, Baolin Niu, Qianming Bai and Xiaobo Li
    Citation: Lipids in Health and Disease 2019 18:203
    Content type: Research Published on:

  42. Apolipoproteins (Apo) are known atherogenic factors that play important roles in many mechanisms related to coronary heart disease (CHD). However, it is unclear whether the apoB/apoA1 ratio is an equal or a be...

    Authors: Min Tian, Rui Li, Zhilei Shan, Dao Wen Wang, Jiangang Jiang and Guanglin Cui
    Citation: Lipids in Health and Disease 2019 18:202
    Content type: Research Published on:

  44. Neuroinflammation plays a major role in the pathogenesis of autism because the cytokine levels are typically disturbed in the brain in autistic patients. Prebiotics-rich diet maintains the healthy gut microbio...

    Authors: Kawther Aabed, Ramesa Shafi Bhat, Abeer Al-Dbass, Nadine Moubayed, Norah Algahtani, Nada M. Merghani, Azizah Alanazi, Naima Zayed and Afaf El-Ansary
    Citation: Lipids in Health and Disease 2019 18:200
    Content type: Research Published on:

    The Correction to this article has been published in Lipids in Health and Disease 2021 20:61

  45. The triglyceride (TG) to high-density lipoprotein cholesterol (HDL-C) ratio (TG/HDL-C) has been suggested as a simple method to identify unfavorable cardiovascular (CV) outcomes in the general population. The ...

    Authors: Xiaojiang Zhan, Mei Yang, Ruitong Zhou, Xin Wei, Yanbing Chen and Qinkai Chen
    Citation: Lipids in Health and Disease 2019 18:199
    Content type: Research Published on:

  46. Previous studies reported that stature is inversely related to the risk of cardiovascular disease. However, there is limited evidence on the association between height and lipid profiles. We aimed to examine t...

    Authors: Mi Yeon Lee, Ga Eun Nam, Kyungdo Han, Da Hye Kim, Yang Hyun Kim, Kyung Hwan Cho and Yong Gyu Park
    Citation: Lipids in Health and Disease 2019 18:198
    Content type: Research Published on:

  47. Excessive intrahepatic lipid accumulation is the major characteristic of nonalcoholic fatty liver disease (NAFLD). We sought to identify the mechanisms involved in hepatic triglyceride (TG) homeostasis. Forkhe...

    Authors: Liu Wang, Xiaopeng Zhu, Xiaoyang Sun, Xinyu Yang, Xinxia Chang, Mingfeng Xia, Yan Lu, Pu Xia, Hongmei Yan, Hua Bian and Xin Gao
    Citation: Lipids in Health and Disease 2019 18:197
    Content type: Research Published on:

  48. The present study was focused on the optimization of yield of the essential oil extraction from leaves of Lawsonia inermis, and the determination of chemical composition, antioxidant activities, and lipid peroxyd...

    Authors: Asma Elaguel, Imen Kallel, Bochra Gargouri, Ichrak Ben Amor, Bilel Hadrich, Ezeddine Ben Messaoud, Radhouane Gdoura, Saloua Lassoued and Ahmed Gargouri
    Citation: Lipids in Health and Disease 2019 18:196
    Content type: Research Published on:

  49. Increased macrophage and foam cell apoptosis during early atherogenesis retards plaque progression by impeding foam cell formation, suppressing inflammation and limiting lesion cellularity. Our previous in vit...

    Authors: Shipra Bhansali, Shivani Khatri and Veena Dhawan
    Citation: Lipids in Health and Disease 2019 18:195
    Content type: Short report Published on:

  50. Research indicates that low omega-3 polyunsaturated fatty acid (n-3 PUFA) may be associated with decreased cognitive function. This study examined the association between n-3 PUFA status and cognitive function...

    Authors: Rebecca L. Cook, Helen M. Parker, Cheyne E. Donges, Nicholas J. O’Dwyer, Hoi Lun Cheng, Katharine S. Steinbeck, Eka P. Cox, Janet L. Franklin, Manohar L. Garg and Helen T. O’Connor
    Citation: Lipids in Health and Disease 2019 18:194
    Content type: Research Published on:
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Lipids in Health and Disease

ISSN: 1476-511X