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  1. Aerobic exercise can decrease postprandial triglyceride (TG) concentrations but the relationship between exercise-induced energy deficits and postprandial lipemia is still unclear. The aim of the present study...

    Authors: Chih-Hui Chiu, Stephen Francis Burns, Tsung-Jen Yang, Yi-Hsin Chang, Yi-Liang Chen, Cheng-Kang Chang and Ching-Lin Wu
    Citation: Lipids in Health and Disease 2014 13:177
    Content type: Research Published on:

  2. Evidence from clinical studies support the fact that abnormal cholesterol metabolism in the brain leads to progressive cognitive dysfunction. The low-density lipoprotein receptor (LDLR) is well-known for its r...

    Authors: Shao-hua Wang, Yan Huang, Yang Yuan, Wen-qing Xia, Pin Wang and Rong Huang
    Citation: Lipids in Health and Disease 2014 13:175
    Content type: Research Published on:

  3. Hypertension has a significant relevance as a cardiovascular risk factor. A consistent increase on world’s Metabolic Syndrome (MetS) incidence has been associated with an epidemic cardiovascular risk in differ...

    Authors: Andrei Alkmim Teixeira, Mauro Sergio Marrocos, Beata Marie Redublo Quinto, Maria Aparecida Dalboni, Cassio Jose de Oliveira Rodrigues, Silmara de Melo Carmona, Mariana Kuniyoshi and Marcelo Costa Batista
    Citation: Lipids in Health and Disease 2014 13:174
    Content type: Research Published on:

  4. The endocannabinoids system (ECs) mediated mainly by CB1 and CB2 receptors plays an important role in non-alcoholic fatty liver disease by regulating lipid metabolism. This study is to further investigate the ...

    Authors: Dongmei Shi, Xi zhan, Xiaofeng Yu, Minglei Jia, Ying Zhang, Jianfeng Yao, Xiaona Hu and Zhijun Bao
    Citation: Lipids in Health and Disease 2014 13:173
    Content type: Research Published on:

  5. All-trans retinoic acid (ATRA, tretinoin) is a vitamin A derivative commonly used in the treatment of diverse conditions ranging from cancer to acne. In a fraction of predisposed individuals, the administratio...

    Authors: Michaela Krupková, František Liška, Lucie Šedová, Drahomíra Křenová, Vladimír Křen and Ondřej Šeda
    Citation: Lipids in Health and Disease 2014 13:172
    Content type: Research Published on:

  7. The disorder of triglyceride (TG) metabolism leading to hypertriglyceridemia is an independent risk factor for coronary artery disease (CAD). Variants in the apolipoprotein C3 (APOC3) gene were found to be ass...

    Authors: FengHe Cui, KeZhong Li, YunFeng Li, XueWu Zhang and ChangShan An
    Citation: Lipids in Health and Disease 2014 13:170
    Content type: Research Published on:

  8. This study investigated anti-obesity effects of seven different solvent (n-hexane, toluene, dicholoromethane, ethyl acetate, absolute methanol, 80% methanol and deionized water) extracts of germinated brown ri...

    Authors: See Meng Lim, Yong Meng Goh, Wen Bin Kuan and Su Peng Loh
    Citation: Lipids in Health and Disease 2014 13:169
    Content type: Research Published on:

  9. Endothelial dysfunction is implicated in the initiation and progression of atherosclerosis. Whether atorvastatin combined with rosiglitazone has synergistic effects on endothelial function improvement in the s...

    Authors: Wei-Li Zhang, Wen-Ju Yan, Bei Sun and Zhi-Peng Zou
    Citation: Lipids in Health and Disease 2014 13:168
    Content type: Research Published on:

  10. Previously, we identified three loci affecting HDL-cholesterol levels in a screen for ENU-induced mutations in mice and discovered two mutated genes. We sought to identify the third mutated gene and further ch...

    Authors: Joan Helmering, Todd Juan, Chi Ming Li, Mark Chhoa, Will Baron, Tibor Gyuris, William G Richards, James R Turk, Jeff Lawrence, Patrick A Cosgrove, Jim Busby, Ki Won Kim, Stephen A Kaufman, Connie Cummings, George Carlson, Murielle M Véniant…
    Citation: Lipids in Health and Disease 2014 13:167
    Content type: Research Published on:

  11. Micronutrients in rapeseed such as polyphenols, tocopherols, phytosterols and phospholipids in rapeseed exert potential benefit to atherosclerosis. Some part of these healthy components substantially lost duri...

    Authors: Jiqu Xu, Congcong Ma, Ling Han, Hui Gao, Qi Zhou, Mei Yang, Chang Chen, Qianchun Deng, Qingde Huang and Fenghong Huang
    Citation: Lipids in Health and Disease 2014 13:166
    Content type: Research Published on:

  12. Our previous study has shown that regardless of a relatively high amount of cholesterol, squid homogenate lowers serum and hepatic cholesterol in animals. Since this work, we have developed a new method to inh...

    Authors: Yasuo Nagata, Youhei Noguchi, Shizuka Tamaru, Koichi Kuwahara, Akira Okamoto, Kazuhito Suruga, Kazunori Koba and Kazunari Tanaka
    Citation: Lipids in Health and Disease 2014 13:165
    Content type: Research Published on:

  13. Several studies have analyzed the association of body mass index (BMI) with either the prevalence or incidence of type 2 diabetes (T2D), but no study from Europe or North America has yet analyzed and compared ...

    Authors: Mashhood Ahmed Sheikh, Eiliv Lund and Tonje Braaten
    Citation: Lipids in Health and Disease 2014 13:164
    Content type: Research Published on:

  14. High-density lipoprotein (HDL) has been shown to confer cardiovascular protection in clinical and epidemiologic studies. Emerging evidence suggests that many of the cardioprotective functions of HDL may be due...

    Authors: Fan Wang and Ping Ye
    Citation: Lipids in Health and Disease 2014 13:163
    Content type: Hypothesis Published on:

  15. Chronic kidney disease (CKD) is known to be one of the causes of cardiovascular disease and end-stage renal disease. Among the several treatable risk factors of CKD, that of dyslipidemia is relatively controve...

    Authors: Asahi Hishida, Kenji Wakai, Mariko Naito, Shino Suma, Tae Sasakabe, Nobuyuki Hamajima, Satoyo Hosono, Mikako Horita, Tanvir Chowdhury Turin, Sadao Suzuki, Tara Sefanya Kairupan, Haruo Mikami, Keizo Ohnaka, Isao Watanabe, Hirokazu Uemura, Michiaki Kubo…
    Citation: Lipids in Health and Disease 2014 13:162
    Content type: Research Published on:

  16. Sphingolipids are increasingly recognized to play a role in insulin resistance and diabetes. Recently we reported significant elevations of 1-deoxysphingolipids (1-deoxySL) - an atypical class of sphingolipids...

    Authors: Nancy Wei, Jessica Pan, Rodica Pop-Busui, Alaa Othman, Irina Alecu, Thorsten Hornemann and Florian S Eichler
    Citation: Lipids in Health and Disease 2014 13:161
    Content type: Short report Published on:

  17. The main goal of this randomized controlled single-blinded pilot study was to study whether, independent of weight loss, a Palaeolithic-type diet alters characteristics of the metabolic syndrome. Next we searc...

    Authors: Inge Boers, Frits AJ Muskiet, Evert Berkelaar, Erik Schut, Ria Penders, Karine Hoenderdos, Harry J Wichers and Miek C Jong
    Citation: Lipids in Health and Disease 2014 13:160
    Content type: Research Published on:

  18. Waist circumference, a metabolic syndrome (MetSy) criterion, is not routinely measured in clinical practice making early identification of individuals with MetSy challenging. It has been argued that ratios of ...

    Authors: Danijela Gasevic, Jiri Frohlich, GB John Mancini and Scott A Lear
    Citation: Lipids in Health and Disease 2014 13:159
    Content type: Research Published on:

  19. Atherogenic dyslipoproteinemia is one of the most important risk factor for atherosclerotic changes development. Hypothyroidism is one of the most common causes of secondary dyslipidemias which results from re...

    Authors: Zuzana Minarikova, Ludovit Gaspar, Peter Kruzliak, Zuzana Celecová and Stanislav Oravec
    Citation: Lipids in Health and Disease 2014 13:158
    Content type: Research Published on:

  20. Several studies have identified APOB as a candidate gene predisposing individuals to dyslipidemia. Polymorphisms including the signal peptide (rs11279109), codon 2488 XbaI (rs1042031), codon 3611 MspI (rs693), co...

    Authors: Suzanne A. Al-Bustan, Majed A. Alnaqeeb, Babitha G. Annice, Ghada A. Ebrahim and Thanaa M. Refai
    Citation: Lipids in Health and Disease 2014 13:157
    Content type: Research Published on:

  21. Diabetic retinopathy, the main microvascular complications of diabetes and one of the leading causes of blindness worldwide. Interesting reports on the role of inflammatory/proangiogenic high mobility group 1 ...

    Authors: Yan Gong, Xin Jin, Quan-Shun Wang, Shi-Hui Wei, Bao-Ke Hou, Hong-Yang Li, Mao-Nian Zhang and Zhao-Hui Li
    Citation: Lipids in Health and Disease 2014 13:156
    Content type: Research Published on:

  22. Deregulated secretion of adipokines contributes to subclinical systemic inflammation associated with type 2 diabetes mellitus (T2DM). However, the mechanisms underlying are not fully understood. Hydrogen sulfi...

    Authors: Zhe Pan, Hanbo Wang, Yuantao Liu, Chunxiao Yu, Yuchao Zhang, Jicui Chen, Xiangdong Wang and Qingbo Guan
    Citation: Lipids in Health and Disease 2014 13:155
    Content type: Research Published on:

  23. The aim of the present meta-analysis of cohort studies was to focus on monounsaturated fat (MUFA) and cardiovascular disease, cardiovascular mortality as well as all-cause mortality, and to distinguish between...

    Authors: Lukas Schwingshackl and Georg Hoffmann
    Citation: Lipids in Health and Disease 2014 13:154
    Content type: Research Published on:

  24. Many drugs are substrates for P-glycoprotein (P-gp) and interactions involving P-gp may be relevant to clinical practice. Co-administration with P-gp inhibitors or inducers changes the absorption profile as we...

    Authors: Kristina Sachs-Barrable, Jerald W. Darlington and Kishor M. Wasan
    Citation: Lipids in Health and Disease 2014 13:153
    Content type: Research Published on:

  25. An important inter-individual variability in the response of insulin sensitivity following a fish oil supplementation has been observed. The objective was to examine the associations between single nucleotide ...

    Authors: Annie Bouchard-Mercier, Iwona Rudkowska, Simone Lemieux, Patrick Couture, Louis Pérusse and Marie-Claude Vohl
    Citation: Lipids in Health and Disease 2014 13:152
    Content type: Research Published on:

  26. Polyunsaturated fatty acid (PUFA) intake favorably affects chronic inflammatory-related diseases such as cardiovascular disease; however, the relationship between the PUFA and inflammatory factors in the healt...

    Authors: Xiaomei Yu, Tao Huang, Xiumei Weng, Tianxing Shou, Qiang Wang, Xiaoqiong Zhou, Qinxin Hu and Duo Li
    Citation: Lipids in Health and Disease 2014 13:151
    Content type: Research Published on:

  27. The migration of T cell to atherosclerotic lesions is proposed to be involved in the pathogenesis of the atherosclerosis. Sphingosine 1-phosphate (S1P), a bioactive lysophospholipid released from activated pla...

    Authors: Junko Iino, Makoto Osada, Makoto Kurano, Makoto Kaneko, Ryunosuke Ohkawa, Yumiko Satoh, Shigeo Okubo, Yukio Ozaki, Minoru Tozuka, Nelson H. Tsuno and Yutaka Yatomi
    Citation: Lipids in Health and Disease 2014 13:150
    Content type: Research Published on:

  28. Previous studies suggested that Apolipoprotein AI (ApoAI) and apolipoprotein B (ApoB) gene polymorphisms may result in lipid metabolism disorders. Genetic polymorphisms in these genes may be associated with th...

    Authors: Ji-Min Yin, Zhao Liu, Shi-Chang Zhao, Yan-Jie Guo and Zhong-Tang Liu
    Citation: Lipids in Health and Disease 2014 13:149
    Content type: Research Published on:

  29. We have previously demonstrated that carrying the apolipoprotein (apo) E epsilon 4 (E4+) genotype disrupts omega-3 fatty acids (n − 3 PUFA) metabolism. Here we hypothesise that the postprandial clearance of n − 3...

    Authors: Valérie Conway, Marie-Julie Allard, Anne-Marie Minihane, Kim G. Jackson, Julie A. Lovegrove and Mélanie Plourde
    Citation: Lipids in Health and Disease 2014 13:148
    Content type: Research Published on:

  30. GP78 is a membrane-anchored ubiquitin ligase mediating the degradation of 3-hydroxy-3-methyl-glutaryl-CoA coenzyme A reductase (HMGCR) and Insig-1, which was very essential for the synthesis of cholesterol pro...

    Authors: Erdenbat Cha, Zhen-Yan Fu, Yi-Tong Ma, Qing Zhu, Xiang Xie and Fen Liu
    Citation: Lipids in Health and Disease 2014 13:1
    Content type: Research Published on:

    The Retraction Note to this article has been published in Lipids in Health and Disease 2015 14:78

  32. Psychosocial stress is one of the risk factors for atherosclerosis. As occlusal disharmony induces psychological stress, we hypothesized that psychological stress by occlusal disharmony accelerates atheroscler...

    Authors: Daisuke Ekuni, Toshiki Yoneda, Yasumasa Endo, Kenta Kasuyama, Koichiro Irie, Shinsuke Mizutani, Tetsuji Azuma, Takaaki Tomofuji and Manabu Morita
    Citation: Lipids in Health and Disease 2014 13:144
    Content type: Research Published on:

  33. The cytochrome P450, family 1, subfamily A, polypeptide 1 (CYP1A1) gene is expressed in the vascular endothelium, which metabolizes arachidonic acid into 20-hydroxyeicosatetraenoic acid (20-HETE) and epoxyeicosat...

    Authors: Jin-Guo Zou, Yi-Tong Ma, Xiang Xie, Yi-Ning Yang, Shuo Pan, Dilare Adi, Fen Liu and Bang-Dang Chen
    Citation: Lipids in Health and Disease 2014 13:2
    Content type: Research Published on:

    The Erratum to this article has been published in Lipids in Health and Disease 2015 14:118

  34. Cytochrome P450 (CYP) 2C9 is expressed in the vascular endothelium and metabolizes arachidonic acid to biologically active epoxyeicosatrienoic acids (EETs), which have the crucial role in the modulation of car...

    Authors: Zhenyan Fu, Qing Zhu, Yitong Ma, Ding Huang, Shuo Pan, Xiang Xie, Fen Liu and Erdenbat Cha
    Citation: Lipids in Health and Disease 2014 13:143
    Content type: Research Published on:

  35. Based on previous observations a potential resort in the therapy of the particularly radioresistant glioma would be its treatment with unsaturated fatty acids (UFAs) combined with irradiation.

    Authors: Otilia Antal, László Hackler Jr, Junhui Shen, Imola Mán, Katalin Hideghéty, Klára Kitajka and László G Puskás
    Citation: Lipids in Health and Disease 2014 13:142
    Content type: Research Published on:

  36. Low-cost practical and reliable tools to evaluated obesity-related cardiometabolic diseases are of clinical practice and public heath relevance worldwide. The aims of this cross-sectional study were to determi...

    Authors: Alessandro de Oliveira, Paula G Cocate, Helen Hermana M Hermsdorff, Josefina Bressan, Mateus Freitas de Silva, Joel Alves Rodrigues and Antônio José Natali
    Citation: Lipids in Health and Disease 2014 13:141
    Content type: Research Published on:

  37. Fatty acids are essential dietary nutrients, and one of their important roles is providing polyunsaturated fatty acids (PUFAs) for the growth and function of nervous tissue. Short chain fatty acids (SCFAs) are...

    Authors: Afaf El-Ansary and Laila Al-Ayadhi
    Citation: Lipids in Health and Disease 2014 13:140
    Content type: Research Published on:

  38. Breast cancer is the most common cancer amongst Malaysian women. Both the disease and its treatment can disrupt the lives of the woman and adversely affect all aspects of life and thus can alter a woman’s qual...

    Authors: Kim Sooi Law, Nizuwan Azman, Eshaifol Azam Omar, Muhammad Yusri Musa, Narazah Mohd Yusoff, Siti Amrah Sulaiman and Nik Hazlina Nik Hussain
    Citation: Lipids in Health and Disease 2014 13:139
    Content type: Research Published on:

  39. Thymus algeriensis Boiss. et Reut. (Lamiaceae), popularly known as “mougecha” or “mazoukcha” is prolific in Mediterranean regions, mostly in North Africa, and is used in folk medicine to treat of stomach diseases...

    Authors: Fatma Guesmi, Manel Ben Ali, Taha Barkaoui, Wiem Tahri, Mondher Mejri, Mossadok Ben-Attia, Houda Bellamine and Ahmed Landoulsi
    Citation: Lipids in Health and Disease 2014 13:138
    Content type: Research Published on:

  40. It has proven difficult to compare the bioavailability of krill oil (KO) vs. fish oil (FO) due to several of the characteristics of KO. These include the lower concentration of the active ingredients, eicosape...

    Authors: Norman Salem Jr and Connye N Kuratko
    Citation: Lipids in Health and Disease 2014 13:137
    Content type: Commentary Published on:

  42. Epidemiological studies have shown that chronic kidney disease (CKD) is an important risk factor for atherosclerosis and cardiovascular disease (CAD). The aim of the study was to determine markers of increased...

    Authors: Anna Gluba-Brzózka, Marta Michalska-Kasiczak, Beata Franczyk-Skóra, Marek Nocuń, Maciej Banach and Jacek Rysz
    Citation: Lipids in Health and Disease 2014 13:135
    Content type: Research Published on:

  43. Atherosclerosis is associated with multiple genetic and modifiable risk factors. There is an increasing body of evidences to indicate that epigenetic mechanisms also play an essential role in atherogenesis by ...

    Authors: Shuyu Zhou, Zhizhong Zhang and Gelin Xu
    Citation: Lipids in Health and Disease 2014 13:134
    Content type: Review Published on:

  44. The prognosis for hyper-high-density lipoprotein (HDL) cholesterolemic patients has not been fully elucidated. We conducted a post hoc analysis of MEGA study data to investigate prospectively the incidence of ...

    Authors: Haruo Nakamura and Kyoichi Mizuno
    Citation: Lipids in Health and Disease 2014 13:133
    Content type: Research Published on:

  45. Twist 1 is highly expressed in adipose tissue and has been associated with obesity and related disorders. However, the molecular function of Twist 1 in adipose tissue is unclear. Twist 1 has been implicated in...

    Authors: Wanshan Ma, Sumei Lu, Tao Sun, Xiangdong Wang, Yongmei Ma, Xiaoli Zhang, Ruxing Zhao and Yunshan Wang
    Citation: Lipids in Health and Disease 2014 13:132
    Content type: Research Published on:

  46. Hyperlipidemia, a metabolic disorder of lipids, is a well known risk factor of cardiovascular events and metabolic syndrome. In this study, the in vivo lipid-lowering activity of the triterpene (Methyl-3β-hydroxy...

    Authors: Kgothatso E Machaba, Sinazo Z Z Cobongela, Rebamang A Mosa, Lawal A Oladipupo, Trayana G Djarova and Andy R Opoku
    Citation: Lipids in Health and Disease 2014 13:131
    Content type: Research Published on:

  47. Hepatitis B virus (HBV) infection poses a serious threat to human health, with China being one of the highly affected countries. However, the pathogenesis of chronic hepatitis B (CHB) is still unclear. Apolipo...

    Authors: Weichao Jiang, Lei Zheng, Qianqian Yang, Zhouying Huang and Xiaobei Wang
    Citation: Lipids in Health and Disease 2014 13:130
    Content type: Research Published on:

  48. Metabolic syndrome (MS) increases a risk of developing cardiovascular disease (CVD) and type 2 diabetes mellitus (T2DM). The Vitamin D Receptor gene (VDR) may be important for developing MS. The aim of this st...

    Authors: Yi Zhao, Sha Liao, Jun He, Yanan Jin, Hailong Fu, Xiaoying Chen, Xuemin Fan, Hongxia Xu, Xiuying Liu, Jing Jin and Yuhong Zhang
    Citation: Lipids in Health and Disease 2014 13:129
    Content type: Research Published on:

  49. Although hypercholesterolemia is a major risk factor for coronary artery disease (CAD), only limited data are available regarding its direct effect on myocardial function apart from CAD. The aim of this study ...

    Authors: Liyun Liu, Yuming Mu, Wei Han and Chunmei Wang
    Citation: Lipids in Health and Disease 2014 13:128
    Content type: Research Published on:

  50. The CYP7A1 gene polymorphism has been reported to be associated with gallbladder stone disease (GSD) and serum lipid levels, but the results were inconsistent. This meta-analysis aimed to evaluate the influence o...

    Authors: Qiang Cai, Zhen-Qiang Wang, Qu Cai, Chen Li, Er-Zhen Chen and Zhao-Yan Jiang
    Citation: Lipids in Health and Disease 2014 13:126
    Content type: Research Published on:
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Lipids in Health and Disease

ISSN: 1476-511X