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  1. It was investigated whether dietary polyunsaturated fatty acids (PUFA) could influence colonic injury, tissue DNA damage, cytokines and myeloperoxidase activity (MPO) and plasma corticosterone in DSS-induced c...

    Authors: Karina V Barros, Roberta AN Xavier, Gilclay G Abreu, Carlos AR Martinez, Marcelo L Ribeiro, Alessandra Gambero, Patrícia O Carvalho, Claudia MO Nascimento and Vera LF Silveira

    Citation: Lipids in Health and Disease 2010 9:68

    Content type: Research

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  2. Poor control of blood pressure leads to hypertension which is a major risk factor for development of cardiovascular disease. The present study aimed to explore possible mechanisms of elevation in blood pressur...

    Authors: Xin-Fang Leong, Mohd Rais Mustafa, Srijit Das and Kamsiah Jaarin

    Citation: Lipids in Health and Disease 2010 9:66

    Content type: Research

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  3. Experimental evidences demonstrate that vegetable derived extracts inhibit cholesterol absorption in the gastrointestinal tract. To further explore the mechanisms behind, we modeled duodenal contents with seve...

    Authors: Mariona Jové, José CE Serrano, Maria Josep Bellmunt, Anna Cassanyé, Neus Anglès, Jordi Reguant, José R Morelló, Reinald Pamplona and Manuel Portero-Otín

    Citation: Lipids in Health and Disease 2010 9:65

    Content type: Research

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  4. Recent studies have shown that dietary red palm oil (RPO) supplementation improves functional recovery following ischaemia/reperfusion in isolated hearts. The main aim of this study was to investigate the effe...

    Authors: Dirk J Bester, Krisztina Kupai, Tamas Csont, Gergu Szucs, Csaba Csonka, Adriaan J Esterhuyse, Peter Ferdinandy and Jacques Van Rooyen

    Citation: Lipids in Health and Disease 2010 9:64

    Content type: Research

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  5. Disrupted cholesterol regulation leading to increased circulating and membrane cholesterol levels is implicated in many age-related chronic diseases such as cardiovascular disease (CVD), Alzheimer's disease (A...

    Authors: Rishikesh Mankidy, Pearson WK Ahiahonu, Hong Ma, Dushmanthi Jayasinghe, Shawn A Ritchie, Mohamed A Khan, Khine K Su-Myat, Paul L Wood and Dayan B Goodenowe

    Citation: Lipids in Health and Disease 2010 9:62

    Content type: Research

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  6. Cholesterol deposition in arterial wall drives atherosclerosis. The key goal of this study was to examine the relationship between plaque cholesterol content and patient characteristics that typically associat...

    Authors: Zhu Chen, Marina Ichetovkin, Marc Kurtz, Emanuel Zycband, Douglas Kawka, John Woods, Xuanmin He, Andrew S Plump and Eric Hailman

    Citation: Lipids in Health and Disease 2010 9:61

    Content type: Research

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  7. The expression of some genes controlling energy homeostasis could be regulated by epigenetic mechanisms that may play a role in body weight regulation. Thus, it is known that various nutritional factors affect...

    Authors: Almudena Lomba, Fermín I Milagro, Diego F García-Díaz, Amelia Marti, Javier Campión and J Alfredo Martínez

    Citation: Lipids in Health and Disease 2010 9:60

    Content type: Research

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  8. phospholipid transfer protein (PLTP) plays important roles in lipoprotein metabolism and atherosclerosis and is expressed by macrophages and macrophage foam cells (MFCs). The aim of the present study was to de...

    Authors: Marius R Robciuc, Jari Metso, Anca Sima, Christian Ehnholm and Matti Jauhiainen

    Citation: Lipids in Health and Disease 2010 9:59

    Content type: Research

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  9. To describe the lipid profile of women prior to, during and after pregnancy and to assess the effect of consecutive pregnancies on the plasma lipid profile.

    Authors: David Mankuta, Matan Elami-Suzin, Asher Elhayani and Shlomo Vinker

    Citation: Lipids in Health and Disease 2010 9:58

    Content type: Research

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  10. Cytoplasmic lipid-droplets are common inclusions of eukaryotic cells. Lipid-droplet binding thalidomide analogs (2,6-dialkylphenyl-4/5-amino-substituted-5,6,7-trifluorophthalimides) with potent anticancer acti...

    Authors: László G Puskás, Liliána Z Fehér, Csaba Vizler, Ferhan Ayaydin, Erzsébet Rásó, Eszter Molnár, István Magyary, Iván Kanizsai, Márió Gyuris, Ramóna Madácsi, Gabriella Fábián, Klaudia Farkas, Péter Hegyi, Ferenc Baska, Béla Ózsvári and Klára Kitajka

    Citation: Lipids in Health and Disease 2010 9:56

    Content type: Research

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  11. Forearm blood flow responses during mental stress are greater in individuals homozygous for the Glu27 allele. A high-fat meal is associated with impaired endothelium-dependent dilatation. We investigated the i...

    Authors: Marcia MG Gowdak, Mateus C Laterza, Maria Urbana PB Rondon, Ivani C Trombetta, Alexandre C Pereira, José Eduardo Krieger and Carlos Eduardo Negrão

    Citation: Lipids in Health and Disease 2010 9:55

    Content type: Research

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  12. This study compared LDL, HDL, and VLDL subclasses in overweight or obese adults consuming either a reduced carbohydrate (RC) or reduced fat (RF) weight maintenance diet for 9 months following significant weigh...

    Authors: James D LeCheminant, Bryan K Smith, Eric C Westman, Mary C Vernon and Joseph E Donnelly

    Citation: Lipids in Health and Disease 2010 9:54

    Content type: Short paper

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  13. Our aim was to evaluate the effects of soybean oil treatment for 15 days on arterial and ventricular pressure, myocardial mechanics and proteins involved in calcium handling.

    Authors: Rogério Faustino Ribeiro Junior, Aurélia Araújo Fernandes, Eduardo Frizzera Meira, Priscila Rossi Batista, Fabiana Dayse Magalhães Siman, Dalton Valentim Vassallo, Alessandra Simão Padilha and Ivanita Stefanon

    Citation: Lipids in Health and Disease 2010 9:53

    Content type: Research

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  14. The Friedewald formula (FF) is useful for calculating serum low-density lipoprotein cholesterol (LDL-C) values, but has a remarkable deviation and limitation especially in hypertriglyceridemia. We modify the f...

    Authors: Yunqin Chen, Xiaojin Zhang, Baishen Pan, Xuejuan Jin, Haili Yao, Bin Chen, Yunzeng Zou, Junbo Ge and Haozhu Chen

    Citation: Lipids in Health and Disease 2010 9:52

    Content type: Short paper

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  15. The effects of hypercholesterolemia on vasomotricity in apolipoprotein E-deficient (ApoE) mice, a murine model of spontaneous atherosclerosis, are still unclear. The studies were mostly performed in conductanc...

    Authors: Maine S Cola, Agata L Gava, Silvana S Meyrelles and Elisardo C Vasquez

    Citation: Lipids in Health and Disease 2010 9:51

    Content type: Short paper

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  16. Oxidative stress is supposed to increase lipid accumulation by stimulation of hepatic lipogenesis at transcriptional level. This study was performed to investigate the role of glutathione in the regulation of ...

    Authors: Corinna Brandsch, Tobias Schmidt, Diana Behn, Kristin Weiße, Andreas S Mueller and Gabriele I Stangl

    Citation: Lipids in Health and Disease 2010 9:50

    Content type: Research

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  17. The novel compound 1a is one of the isoflavone fatty acid esters. In order to investigate the anti-obesity effect of compound 1a and its potential mechanism of influence in adipocyte differentiation, Obese male C...

    Authors: Yao Yao, Xiao-Bo Li, Wei Zhao, Yan-Yan Zeng, Hong Shen, Hua Xiang and Hong Xiao

    Citation: Lipids in Health and Disease 2010 9:49

    Content type: Research

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  18. Apolipoprotein B (apoB) containing lipoproteins, i.e. VLDL, LDL and Lp(a), are consequently lowered by ACTH treatment in humans. This is also seen as reduced plasma apoB by 20-30% and total cholesterol by 30-4...

    Authors: Maria Skoog, Maria Berggren-Söderlund, Peter Nilsson-Ehle and Ning Xu

    Citation: Lipids in Health and Disease 2010 9:48

    Content type: Research

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  19. Endocannabinoids (eCBs) are ubiquitous lipid mediators that act on specific (CB1, CB2) and non-specific (TRPV1, PPAR) receptors. Despite many experimental animal studies proved eCB involvement in the pathogene...

    Authors: Marcello Naccarato, Daniela Pizzuti, Stefania Petrosino, Marco Simonetto, Laura Ferigo, Fabio Chiodo Grandi, Gilberto Pizzolato and Vincenzo Di Marzo

    Citation: Lipids in Health and Disease 2010 9:47

    Content type: Research

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  20. Paraoxonase-1 (PON1), a lactonase synthesized by the liver, circulates in blood bound to high-density lipoproteins (HDL). This enzyme is thought to degrade oxidized phospholipids and play an important role in ...

    Authors: Judit Marsillach, Gerard Aragonès, Bharti Mackness, Michael Mackness, Anna Rull, Raúl Beltrán-Debón, Juan Pedro-Botet, Carlos Alonso-Villaverde, Jorge Joven and Jordi Camps

    Citation: Lipids in Health and Disease 2010 9:46

    Content type: Research

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  21. The body mass index (BMI) is the most commonly used marker for evaluating obesity related risks, however, central obesity measures have been proposed to be more informative. Lipid accumulation product (LAP) is...

    Authors: Mohammadreza Bozorgmanesh, Farzad Hadaegh and Fereidoun Azizi

    Citation: Lipids in Health and Disease 2010 9:45

    Content type: Research

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  22. Piper sarmentosum (P.s) has flavonoid component in its leaves which has antioxidative effect. To date, its effect on atherosclerosis has not been studied histologically.

    Authors: Adel A Amran, Zaiton Zakaria, Faizah Othman, Srijit Das, Santhana Raj and Nor-Anita M M Nordin

    Citation: Lipids in Health and Disease 2010 9:44

    Content type: Research

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  23. The endocannabinoids, anandamide and 2-AG, are produced by adipocytes, where they stimulate lipogenesis via cannabinoid CB1 receptors and are under the negative control of leptin and insulin. Endocannabinoid leve...

    Authors: Giovanni Annuzzi, Fabiana Piscitelli, Lucrezia Di Marino, Lidia Patti, Rosalba Giacco, Giuseppina Costabile, Lutgarda Bozzetto, Gabriele Riccardi, Roberta Verde, Stefania Petrosino, Angela A Rivellese and Vincenzo Di Marzo

    Citation: Lipids in Health and Disease 2010 9:43

    Content type: Research

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  24. In this study we aimed to assess lipid peroxidation during carotid endarterectomy by the formation of PUFA hydroperoxides (PUFAHP) and isoprostanes (IP) and concomitant peroxisomal beta-oxidation as a physiolo...

    Authors: Sebastiano Banni, Roberto Montisci, Roberto Sanfilippo, Gabriele Finco, Daniela Sanna, Elena Giordano, Elisabetta Murru, Lina Cordeddu, Gianfranca Carta, Donata Banni and Antonio Marchi

    Citation: Lipids in Health and Disease 2010 9:41

    Content type: Research

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  25. There are many reports about the anti-arrhythmic effects of ω-3 polyunsaturated fatty acids, however, the mechanisms are still not completely delineated. The purpose of this study was to investigate the charac...

    Authors: Ru-xing Wang, Xiao-rong Li, Tao Guo, Li-ping Sun, Su-xia Guo, Zhen-Yu Yang, Xiang-Jun Yang and Wen-ping Jiang

    Citation: Lipids in Health and Disease 2010 9:39

    Content type: Research

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  26. Dexamethasone (DEX) is known to induce diabetes and dyslipidemia. We have compared fasting triacylglycerol and cholesterol concentrations across 20 lipoprotein fractions and glucose tolerance in control (stand...

    Authors: Michaela Krupková, Lucie Šedová, František Liška, Drahomíra Křenová, Vladimír Křen and Ondřej Šeda

    Citation: Lipids in Health and Disease 2010 9:38

    Content type: Short paper

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  27. Chicken meat with reduced concentration of arachidonic acid (AA) and reduced ratio between omega-6 and omega-3 fatty acids has potential health benefits because a reduction in AA intake dampens prostanoid signali...

    Authors: Anna Haug, Ingrid Olesen and Olav A Christophersen

    Citation: Lipids in Health and Disease 2010 9:37

    Content type: Research

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  28. Adipocytes contribute to inflammation and the innate immune response through expression of inflammatory mediators. High levels of these mediators have been related to chronic inflammation state and insulin res...

    Authors: Aurelio Ocaña, Cristina Gómez-Asensio, Elena Arranz-Gutiérrez, Carlos Torres, Francisco Javier Señoráns and Guillermo Reglero

    Citation: Lipids in Health and Disease 2010 9:36

    Content type: Research

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  29. Oxidative damage has been proposed as a possible mechanism involved in lead toxicity, specially affecting the liver and kidney. Previous studies have shown the antioxidant effect of Spirulina maxima in several ex...

    Authors: Johny C Ponce-Canchihuamán, Oscar Pérez-Méndez, Rolando Hernández-Muñoz, Patricia V Torres-Durán and Marco A Juárez-Oropeza

    Citation: Lipids in Health and Disease 2010 9:35

    Content type: Research

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  30. Serum apolipoprotein (apo) A-I was considered to be an immune regulator and could suppress pro-inflammatory cytokines generated by activated T cell in some autoimmune diseases. However, the change of serum apo...

    Authors: Bin Zhang, ShuXiang Pu, BinMei Li, JianRui Ying, Xing Wang Song and Cong Gao

    Citation: Lipids in Health and Disease 2010 9:34

    Content type: Research

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  31. The alkylphospholipid analog miltefosine (hexadecylphosphocholine) is a membrane-directed antitumoral and antileishmanial drug belonging to the alkylphosphocholines, a group of synthetic antiproliferative agen...

    Authors: José M Jiménez-López, Pablo Ríos-Marco, Carmen Marco, Josefa L Segovia and María P Carrasco

    Citation: Lipids in Health and Disease 2010 9:33

    Content type: Review

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  32. Paraoxonase-1 (PON1) is an antioxidant enzyme that attenuates the production of the monocyte chemoattractant protein-1 (MCP-1) in vitro. Although oxidation and inflammation are closely related processes, the asso...

    Authors: Sandra Parra, Judit Marsillach, Gerard Aragonès, Anna Rull, Raúl Beltrán-Debón, Carlos Alonso-Villaverde, Jorge Joven and Jordi Camps

    Citation: Lipids in Health and Disease 2010 9:32

    Content type: Short paper

    Published on:

  33. Results from increasing numbers of in vitro and in vivo studies have demonstrated that omega 3 fatty acids incorporated in cell culture media or in the diet of the animals can suppress the growth of cancers. When...

    Authors: Theodore R Witte, Alexander J Salazar, Oscar F Ballester and W Elaine Hardman

    Citation: Lipids in Health and Disease 2010 9:31

    Content type: Research

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  34. Dietary fats have long been associated with human health, and especially cardiovascular disease (CVD). Some observational studies have shown that reduction in dietary fats, and particularly cholesterol is asso...

    Authors: Evangelos Polychronopoulos, George Pounis, Vassiliki Bountziouka, Akis Zeimbekis, Ioanna Tsiligianni, Brikena-Eirini Qira, Efthimios Gotsis, George Metallinos, Christos Lionis and Demosthenes Panagiotakos

    Citation: Lipids in Health and Disease 2010 9:30

    Content type: Short paper

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  35. We recently examined the distribution of abdominal fat, dietary intake and biochemical data in patients with nonalcoholic fatty liver disease (NAFLD) and found that non-obese NAFLD patients did not necessarily...

    Authors: Munechika Enjoji, Kazuyuki Machida, Motoyuki Kohjima, Masaki Kato, Kazuhiro Kotoh, Kazuhisa Matsunaga, Manabu Nakashima and Makoto Nakamuta

    Citation: Lipids in Health and Disease 2010 9:29

    Content type: Short paper

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  36. The association between -250G>A polymorphism in the promoter region of the hepatic lipase gene (LIPC) and plasma high-density lipoprotein cholesterol (HDL-C) concentration is contradictory in diverse ethnics. Bai...

    Authors: Li Meng, Yin Ruixing, Li Yiyang, Long Xingjiang, Li Kela, Liu Wanying, Zhang Lin, Lin Weixiong, Yang Dezhai and Pan Shangling

    Citation: Lipids in Health and Disease 2010 9:28

    Content type: Research

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  37. Friedewald's formula for the estimation of LDL-C concentration is the most often used formula in clinical practice. A recent formula by Anandaraja and colleagues for LDL-C estimation still needs to be evaluate...

    Authors: Ana Vujovic, Jelena Kotur-Stevuljevic, Slavica Spasic, Nada Bujisic, Jelena Martinovic, Milica Vujovic, Vesna Spasojevic-Kalimanovska, Aleksandra Zeljkovic and Dragoljub Pajic

    Citation: Lipids in Health and Disease 2010 9:27

    Content type: Research

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  38. The most important function of collagen and elastin is to induce several mechanical parameters which are known to play a dominant role in governing mechanical properties of the blood vessels. The aortic tissue...

    Authors: Mohamed Anwar K Abdelhalim, N J Siddiqi, AS Alhomida and Mohammed S Al-Ayed

    Citation: Lipids in Health and Disease 2010 9:26

    Content type: Research

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  39. Nonalcoholic fatty liver disease is the most common chronic liver disease in the world, and is becoming increasingly prevalent. Saponins of sea cucumber (SSC) are proven to exhibit various biological activitie...

    Authors: Xiao-Qian Hu, Yu-Ming Wang, Jing-Feng Wang, Yong Xue, Zhao-Jie Li, Koji Nagao, Teruyoshi Yanagita and Chang-Hu Xue

    Citation: Lipids in Health and Disease 2010 9:25

    Content type: Research

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  40. fatty acids are considered to be effective components to promote wound healing and Lucilia sericata larvae are applied clinically to treat intractable wounds. We aimed to investigat the effect of fatty acid extra...

    Authors: Zhen Zhang, Shouyu Wang, Yunpeng Diao, Jianing Zhang and Decheng Lv

    Citation: Lipids in Health and Disease 2010 9:24

    Content type: Research

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  41. There is an increasing number of novel antilipidemic therapies under consideration. The putative hypolipidemic effect of N-acetylcysteine (NAC) and sesame oil was studied in a mouse model of dietary-induced hy...

    Authors: Laskarina-Maria Korou, George Agrogiannis, Alkisti Pantopoulou, Ioannis S Vlachos, Dimitrios Iliopoulos, Theodoros Karatzas and Despoina N Perrea

    Citation: Lipids in Health and Disease 2010 9:23

    Content type: Research

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  42. The aim of the study was to assess the influence of co-existing atrial fibrillation (AF) on inflammatory condition factors, left ventricular function, clinical course and the efficacy of statin treatment of co...

    Authors: Agata Bielecka-Dąbrowa, Jan Henryk Goch, Jacek Rysz, Marek Maciejewski, Ravi Desai, Wilbert S Aronow and Maciej Banach

    Citation: Lipids in Health and Disease 2010 9:21

    Content type: Research

    Published on:

  43. LeptiCore® is a proprietary combination of various ingredients which have been shown to have properties which could be beneficial to weight loss in obese and overweight human subjects. This study evaluates the ef...

    Authors: Dieudonne Kuate, Blanche C O Etoundi, Boris K G Azantsa, Anne-Pascale N Kengne, Judith L Ngondi and Julius E Oben

    Citation: Lipids in Health and Disease 2010 9:20

    Content type: Research

    Published on:

  44. Multiple Sclerosis (MS) patients present a decrease of antioxidants and neuroprotective and immunoregulatory vitamins and an increase of total homocysteine (tHcy), cholesterol (CHL), HDL-cholesterol, and of ce...

    Authors: Giuseppe Salemi, Maria Concetta Gueli, Francesco Vitale, Floriana Battaglieri, Egidio Guglielmini, Paolo Ragonese, Angela Trentacosti, Maria Fatima Massenti, Giovanni Savettieri and Antonino Bono

    Citation: Lipids in Health and Disease 2010 9:19

    Content type: Short paper

    Published on:

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