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  1. The association of peroxisome proliferator-activated receptor delta (PPARD) +294T > C polymorphism and serum lipid levels is inconsistent in several previous studies. Bai Ku Yao is an isolated subgroup of the ...

    Authors: Lin Miao, Rui-Xing Yin, Dong-Feng Wu, Xiao-Li Cao, Qing Li, Xi-Jiang Hu, Ting-Ting Yan, Lynn Htet Htet Aung, De-Zhai Yang and Wei-Xiong Lin

    Citation: Lipids in Health and Disease 2010 9:145

    Content type: Research

    Published on:

  2. Type 2 diabetes is associated with significant cardiovascular morbidity and mortality. Although low-density lipoprotein cholesterol levels may be normal in patients with type 2 diabetes, insulin resistance dri...

    Authors: Krishnaswami Vijayaraghavan

    Citation: Lipids in Health and Disease 2010 9:144

    Content type: Review

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  3. Inflammation has been implicated in cardiovascular disease, and the important role of proteasomes in the development of inflammation and other macrophage functions has been demonstrated. Tocotrienols are poten...

    Authors: Asaf A Qureshi, Julia C Reis, Christopher J Papasian, David C Morrison and Nilofer Qureshi

    Citation: Lipids in Health and Disease 2010 9:143

    Content type: Research

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  4. Statins induces cell cycle arrest, apoptosis, reduction of angiogenic factors, inhibition of the endothelial growth factor, impairing tissue adhesion and attenuation of the resistance mechanisms. The aim of th...

    Authors: Giovani M Favero, Michel F Otuki, Karen A Oliveira, Milton S Bohatch Jr, Primavera Borelli, Francisco E Barros, Durvanei A Maria, Daniel Fernandes and Sergio P Bydlowski

    Citation: Lipids in Health and Disease 2010 9:142

    Content type: Research

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  5. Because abdominal obesity is predisposed to various metabolic disorders, it is of major importance to assess and track the changes with time of this specific fat mass. The main issue for clinicians or research...

    Authors: Maude Gerbaix, Lore Metz, Emeline Ringot and Daniel Courteix

    Citation: Lipids in Health and Disease 2010 9:140

    Content type: Research

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  6. The association of rs1044925 polymorphism in the acyl-CoA:cholesterol acyltransferase-1 (ACAT-1) gene and serum lipid profiles is not well known in different ethnic groups. Bai Ku Yao is a special subgroup of ...

    Authors: Dong-Feng Wu, Rui-Xing Yin, Lynn Htet Htet Aung, Xi-Jiang Hu, Xiao-Li Cao, Lin Miao, Qing Li, Ting-Ting Yan, Jin-Zhen Wu and Shang-Ling Pan

    Citation: Lipids in Health and Disease 2010 9:139

    Content type: Research

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  7. The aim of the present study was to examine how lipid profiles are associated with insulin resistance in Japanese community-dwelling adults.

    Authors: Ryuichi Kawamoto, Yasuharu Tabara, Katsuhiko Kohara, Tetsuro Miki, Tomo Kusunoki, Shuzo Takayama, Masanori Abe, Tateaki Katoh and Nobuyuki Ohtsuka

    Citation: Lipids in Health and Disease 2010 9:138

    Content type: Research

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  8. Rapeseed oil is the principal dietary source of monounsaturated and n-3 polyunsaturated fatty acids in the Northern Europe. However, the effect of rapeseed oil on the markers of subclinical atherosclerosis is ...

    Authors: Ari Palomäki, Hanna Pohjantähti-Maaroos, Marja Wallenius, Päivi Kankkunen, Heikki Aro, Sari Husgafvel, Juha-Matti Pihlava and Kalevi Oksanen

    Citation: Lipids in Health and Disease 2010 9:137

    Content type: Research

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  9. Some patients administered cholesterol-lowering therapies may experience an increase in the proportion of small LDL particles, which may be misinterpreted as a worsening of atherosclerotic coronary heart disea...

    Authors: Harold Bays, Scott Conard, Lawrence A Leiter, Steven Bird, Erin Jensen, Mary E Hanson, Arvind Shah and Andrew M Tershakovec

    Citation: Lipids in Health and Disease 2010 9:136

    Content type: Research

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  10. PUFAs are potent inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, an enzyme catalyzing the conversion of HMGCoA to mevalonate, the rate limiting step in cholesterol biosynthesis. Statin...

    Authors: Maria Notarnicola, Caterina Messa, Maria G Refolo, Valeria Tutino, Angelica Miccolis and Maria G Caruso

    Citation: Lipids in Health and Disease 2010 9:135

    Content type: Research

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  11. Kurozu concentrated liquid (KCL) is used as a health-promoting supplement for the treatment of disorders such as cancer, hyperlipidemia, and hypertension in Japan. We investigated the possible anti-obesity eff...

    Authors: Li-Tao Tong, Yoshinori Katakura, Sayaka Kawamura, Sanae Baba, Yasutake Tanaka, Miyako Udono, Yoshie Kondo, Kumi Nakamura, Katsumi Imaizumi and Masao Sato

    Citation: Lipids in Health and Disease 2010 9:134

    Content type: Research

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  12. Despite significant improvements in the treatment of coronary heart disease (CHD), it is still a major cause of mortality and morbidity among the Iranian population. Epidemiological studies have documented tha...

    Authors: Teymoor Yary, Kourosh Soleimannejad, Firdaus Abd Rahim, Mirnalini Kandiah, Sanaz Aazami, Seyedehozma Jafar Poor, Wong Teck Wee and Golnaz Aazami

    Citation: Lipids in Health and Disease 2010 9:133

    Content type: Research

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  13. 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) catalyzes the conversion of inactive glucocorticoids to active glucocorticoids and plays an important role in the development of obesity and metabolic syndrom...

    Authors: Sakamuri SS Vara Prasad, Anamthathmakula Prashanth, Chodavarapu Pavan Kumar, Sirisha J Reddy, Nappan V Giridharan and Ayyalasomayajula Vajreswari

    Citation: Lipids in Health and Disease 2010 9:132

    Content type: Short paper

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  14. It is designed to investigate the effects of combination therapy of allicin and fenofibrate on the endothelial and liver functions in rats with hyperlipidemia.

    Authors: Weihong Li, Daxin Wang, Guohua Song, Chunxia Zuo, Xianfu Qiao and Shucun Qin

    Citation: Lipids in Health and Disease 2010 9:131

    Content type: Research

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  15. The high incidence of insulin resistance and the metabolic syndrome in South Asians remains unexplained. I propose that a defect in the activity of Δ6 and Δ5 desaturases and consequent low plasma and tissue conce...

    Authors: Undurti N Das

    Citation: Lipids in Health and Disease 2010 9:130

    Content type: Hypothesis

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  16. Dysregulated inflammation in cystic fibrosis (CF) is attributed to an altered production of inflammatory mediators derived from polyunsaturated lipids. In comparison to the arachidonic acid (AA) cascade, littl...

    Authors: Elena Bravo, Mariarosaria Napolitano, Sara Benedetti Valentini and Serena Quattrucci

    Citation: Lipids in Health and Disease 2010 9:129

    Content type: Short paper

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  17. Cardiovascular diseases (CVD) are the main cause of death and disability in developed countries. In most cases, the progress of CVD is influenced by environmental factors and multifactorial inheritance. The pu...

    Authors: Rafael O Alvim, Silvia RS Freitas, Noely E Ferreira, Paulo CJL Santos, Roberto S Cunha, José G Mill, José E Krieger and Alexandre C Pereira

    Citation: Lipids in Health and Disease 2010 9:128

    Content type: Research

    Published on:

  18. This post-hoc analysis compared the lipid-altering efficacy of Ezetimibe/Simvastatin 10/20 mg (EZ/Simva) versus Rosuvastatin 10 mg (Rosuva) in patients stratified by statin potency/dose prior to randomization.

    Authors: Margus Viigimaa, Helena Vaverkova, Michel Farnier, Maurizio Averna, Luc Missault, Mary E Hanson, Qian Dong, Arvind Shah and Philippe Brudi

    Citation: Lipids in Health and Disease 2010 9:127

    Content type: Research

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  19. Conjugated linoleic acids (CLA) are a group of positional and geometric isomers of linoleic acid with proven beneficial influence on health. They show e.g. anticarcinogenic, antiobesity, and antiatherogenic ef...

    Authors: Agnieszka Białek, Andrzej Tokarz, Agnieszka Dudek, Weronika Kazimierska and Wojciech Bielecki

    Citation: Lipids in Health and Disease 2010 9:126

    Content type: Research

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  20. Sleep deprivation has been shown to increase inflammatory markers in rat sera and peripheral blood mononuclear cells. Inflammation is a condition associated with pathologies such as obesity, cancer, and cardio...

    Authors: José C Rosa Neto, Fábio S Lira, Daniel P Venancio, Cláudio A Cunha, Lila M Oyama, Gustavo D Pimentel, Sérgio Tufik, Cláudia M Oller do Nascimento, Ronaldo VT Santos and Marco T de Mello

    Citation: Lipids in Health and Disease 2010 9:125

    Content type: Research

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  21. Heme oxygenase-1 (HO-1), the rate-limiting enzyme in heme catabolism, has been reported to have potential antioxidant properties. However, the role of HO-1 on hepatocyte apoptosis remains unclear. We aim to el...

    Authors: YueMin Nan, RongQi Wang, SuXian Zhao, Fang Han, Wen Juan Wu, LingBo Kong, Na Fu, Li Kong and Jun Yu

    Citation: Lipids in Health and Disease 2010 9:124

    Content type: Research

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  22. The association of methylenetetrahydrofolate reductase (MTHFR) gene polymorphism and serum lipid profiles is still controversial in diverse ethnics. Bai Ku Yao is an isolated subgroup of the Yao minority in Ch...

    Authors: Lin Zhang, Rui-Xing Yin, Wan-Ying Liu, Lin Miao, Dong-Feng Wu, Lynn Htet Htet Aung, Xi-Jiang Hu, Xiao-Li Cao, Jin-Zhen Wu and Shang-Ling Pan

    Citation: Lipids in Health and Disease 2010 9:123

    Content type: Research

    Published on:

  23. The association between modulation of detailed lipoprotein profiles and cholesterol ester transfer (CET) activity by peroxisome proliferator-activated receptor (PPAR)-a agonists in patients with coronary arter...

    Authors: Tetsuro Miyazaki, Kazunori Shimada, Katsumi Miyauchi, Atsumi Kume, Kosei Tanimoto, Takashi Kiyanagi, Katsuhiko Sumiyoshi, Makoto Hiki, Hiroshi Mokuno, Shinya Okazaki, Hitoshi Sato, Takeshi Kurata and Hiroyuki Daida

    Citation: Lipids in Health and Disease 2010 9:122

    Content type: Research

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  24. Intermittent hypoxia (IH), a model of sleep apnea, produces weight loss in animals. We hypothesized that changes in brown adipose tissue (BAT) function are involved in such phenomenon. We investigated the effe...

    Authors: Denis Martinez, Cintia Z Fiori, Diego Baronio, Alicia Carissimi, Renata SR Kaminski, Lenise J Kim, Darlan P Rosa and Ângelo Bos

    Citation: Lipids in Health and Disease 2010 9:121

    Content type: Research

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  25. To investigate the effect of oxidized low density lipoprotein receptor-1 (LOX-1) on tubular epithelial-mesenchymal transition (TEMT) induced by oxidized low-density lipoprotein (ox-LDL) and its mechanism.

    Authors: Rui Wang, Guohua Ding, Wei Liang, Cheng Chen and Hongxia Yang

    Citation: Lipids in Health and Disease 2010 9:120

    Content type: Short paper

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  26. The double-blinded placebo-controlled randomized study has been performed in 51 coronary heart disease (CHD) patients to estimate the effects of time-released garlic powder tablets Allicor on the values of 10-...

    Authors: Igor A Sobenin, Valentin V Pryanishnikov, Lyudmila M Kunnova, Yevgeny A Rabinovich, Danik M Martirosyan and Alexander N Orekhov

    Citation: Lipids in Health and Disease 2010 9:119

    Content type: Research

    Published on:

  27. Atherosclerosis is considered a chronic inflammatory disease in which monocytes and macrophages are critical. These cells express CD14, toll-like receptor (TLR) 2, and TLR4 on their surfaces, are activated by ...

    Authors: Luis Chávez-Sánchez, Karina Chávez-Rueda, Maria Victoria Legorreta-Haquet, Edgar Zenteno, Yadira Ledesma-Soto, Eduardo Montoya-Díaz, Emiliano Tesoro-Cruz, Alejandra Madrid-Miller and Francisco Blanco-Favela

    Citation: Lipids in Health and Disease 2010 9:117

    Content type: Research

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  28. This study aimed to analyze the effects of exercise at the aerobic/anaerobic transition on the markers of non-alcoholic fatty liver disease (NAFLD), insulin sensitivity and the blood chemistry of rats kept on ...

    Authors: José D Botezelli, Rodrigo F Mora, Rodrigo A Dalia, Leandro P Moura, Lucieli T Cambri, Ana C Ghezzi, Fabrício A Voltarelli and Maria AR Mello

    Citation: Lipids in Health and Disease 2010 9:116

    Content type: Research

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  29. Prevalence of dyslipidemia is high and increases even in younger people. The key aim of this study was to explore the group characteristics of patients in different durations of dyslipidemia and provide clues ...

    Authors: Yingying Liu, Puhong Zhang, Wei Wang, Huan Wang, Ling Zhang, Wei Wu and Xiuhua Guo

    Citation: Lipids in Health and Disease 2010 9:115

    Content type: Research

    Published on:

  30. Tree shrew and beijing duck are regarded as animal models resistant to atherosclerosis (AS). This study was carried out to discover the potential mechanism.

    Authors: Hui-rong Liu, Gang Wu, Bing Zhou and Bao-sheng Chen

    Citation: Lipids in Health and Disease 2010 9:114

    Content type: Research

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  31. Nutritional factors play a major role in cancer initiation and development. Dietary polyunsaturated fatty acids (PUFAs) have the ability to induce modifications in the activity of lipoxygenase (LOX) and cycloo...

    Authors: Andrea Comba, Damian M Maestri, María A Berra, Carolina Paola Garcia, Undurti N Das, Aldo R Eynard and María E Pasqualini

    Citation: Lipids in Health and Disease 2010 9:112

    Content type: Research

    Published on:

  32. The enzyme 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) amplifies intracellular glucocorticoid action by converting inactive glucocorticoids to their active forms in vivo. Adipose-specific overexpression of...

    Authors: Sakamuri SS Vara Prasad, Shanmugam S Jeya Kumar, Putcha Uday Kumar, Syed SYH Qadri and Ayyalasomayajula Vajreswari

    Citation: Lipids in Health and Disease 2010 9:111

    Content type: Short paper

    Published on:

  33. Endothelial lipase (EL) is a major determinant of high-density lipoprotein-cholesterol (HDL-C) metabolism, but the association of endothelial lipase gene (LIPG) polymorphism and serum HDL-C levels is scarce and c...

    Authors: Wan-Ying Liu, Rui-Xing Yin, Lin Zhang, Xiao-Li Cao, Lin Miao, Dong-Feng Wu, Lynn Htet Htet Aung, Xi-Jiang Hu, Wei-Xiong Lin and De-Zhai Yang

    Citation: Lipids in Health and Disease 2010 9:110

    Content type: Research

    Published on:

  34. Cytokines (IL-6, IL-10 and TNF-α) are increased after exhaustive exercise in the rat retroperitoneal (RPAT) and mesenteric adipose tissue (MEAT) pads. On the other hand, these cytokines show decreased expressi...

    Authors: Fábio S Lira, José C Rosa, Gustavo D Pimentel, Victor AF Tarini, Ricardo M Arida, Flávio Faloppa, Eduardo S Alves, Cláudia O do Nascimento, Lila M Oyama, Marília Seelaender, Marco T de Mello and Ronaldo VT Santos

    Citation: Lipids in Health and Disease 2010 9:109

    Content type: Research

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  35. Some polyunsaturated fatty acids (PUFAs), if not all, have been shown to have tumoricidal action, but their exact mechanism(s) of action is not clear. In the present study, we observed that n-6 PUFA linoleic a...

    Authors: Xiaofeng Lu, Haining Yu, Qi Ma, Shengrong Shen and Undurti N Das

    Citation: Lipids in Health and Disease 2010 9:106

    Content type: Research

    Published on:

  36. Polyunsaturated fatty acids are essential nutrients for humans. They are structural and functional components of cell membranes and pre-stages of the hormonally and immunologically active eicosanoids. Recent d...

    Authors: Michael Huss, Andreas Völp and Manuela Stauss-Grabo

    Citation: Lipids in Health and Disease 2010 9:105

    Content type: Research

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  37. Oxidized lipoproteins play important roles in the atherosclerotic processes. Oxidized lipoprotein(a) (oxLp(a)) may be more potent in atherosclerotic pathophysiology than native Lp(a), a cardiovascular disease-...

    Authors: Kazuhiko Kotani, Shingo Yamada, Shuumarjav Uurtuya, Toshiyuki Yamada, Nobuyuki Taniguchi and Ikunosuke Sakurabayashi

    Citation: Lipids in Health and Disease 2010 9:103

    Content type: Short paper

    Published on:

  38. It has been well documented that apolipoprotein M (apoM) is principally expressed in the liver and kidney. However we found that there was weak apoM expression in other tissues or organs too, which could not b...

    Authors: Guanghua Luo, Xiaoying Zhang, Qinfeng Mu, Lujun Chen, Lu Zheng, Jiang Wei, Maria Berggren-Söderlund, Peter Nilsson-Ehle and Ning Xu

    Citation: Lipids in Health and Disease 2010 9:102

    Content type: Research

    Published on:

  39. Fish oil is known to improve lifestyle-related diseases. These effects occur partly via activation of PPARs by the n-3 polyunsaturated fatty acids included abundantly in fish oil. We investigated fish oil func...

    Authors: Masaki Wakutsu, Nobuyo Tsunoda, Sachiko Shiba, Etsuko Muraki and Keizo Kasono

    Citation: Lipids in Health and Disease 2010 9:101

    Content type: Research

    Published on:

  40. The body mass index (BMI) is the most commonly used marker for evaluating obesity related risks, however, central obesity measures have been proposed to be more informative. Lipid accumulation product (LAP) is...

    Authors: Mohammadreza Bozorgmanesh, Farzad Hadaegh and Fereidoun Azizi

    Citation: Lipids in Health and Disease 2010 9:100

    Content type: Research

    Published on:

  41. The Berlin Fat Mouse Inbred (BFMI) line is a new mouse model for obesity, which was long-term selected for high fatness. Peroxisome proliferator-activated receptors (PPARs) are involved in the control of energ...

    Authors: Asja Wagener, Helge F Goessling, Armin O Schmitt, Susanne Mauel, Achim D Gruber, Richard Reinhardt and Gudrun A Brockmann

    Citation: Lipids in Health and Disease 2010 9:99

    Content type: Research

    Published on:

  42. Docosahexaenoic acid (DHA, 22:6ω3) is a fundamental component of cell membranes, especially in the brain and retina. In the experimental animal, DHA deficiency leads to suboptimal neurological performance and ...

    Authors: Manuela Martinez, Natalia Ichaso, Fernando Setien, Nuria Durany, Xiao Qiu and William Roesler

    Citation: Lipids in Health and Disease 2010 9:98

    Content type: Research

    Published on:

  43. Low level of high density lipoprotein cholesterol (HDL-C) has high prevalence in the Tehran Lipid and Glucose Study (TLGS) cohort. About 50% of the inter-individual variation in serum HDL-C levels is genetical...

    Authors: Mohammad Ali Kashani Farid, Fereidoun Azizi, Mehdi Hedayati, Maryam S Daneshpour, Ahmad Reza Shamshiri and Fereydoun Siassi

    Citation: Lipids in Health and Disease 2010 9:96

    Content type: Research

    Published on:

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