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  1. Administration of androgens decreases plasma concentrations of high-density lipid cholesterol (HDL-C). However, the mechanisms by which androgens mediate lipid metabolism remain unknown. This present study use...

    Authors: Ye Yi-zhou, Cao Bing, Li Ming-qiu, Wang Wei, Wang Ru-xing, Rui Jun, Wei Liu-yan, Jing Zhao-hui, Ji Yong, Jiao Guo qing and Zou Jian
    Citation: Lipids in Health and Disease 2012 11:168
    Content type: Research Published on:

  3. The present study was performed to investigate the effects of the combination therapy of pinocembrin and simvastatin on the atherosclerotic lesions development in the ApoE−/− mice.

    Authors: Hui Sang, Na Yuan, Shutong Yao, Furong Li, Jiafu Wang, Yongqi Fang and Shucun Qin
    Citation: Lipids in Health and Disease 2012 11:166
    Content type: Research Published on:

  4. Given that acne is a rare condition in societies with higher consumption of omega-3 (n-3) relative to omega-6 (n-6) fatty acids, supplementation with n-3 may suppress inflammatory cytokine production and there...

    Authors: Golandam Khayef, Julia Young, Bonny Burns-Whitmore and Thomas Spalding
    Citation: Lipids in Health and Disease 2012 11:165
    Content type: Short report Published on:

  6. Accumulating evidence suggested that dysregulation of cholesterol homeostasis might be a major etiologic factor in initiating and promoting neurodegeneration in Alzheimer’s disease (AD). ATP-binding cassette t...

    Authors: Zhijie Xiao, Juan Wang, Weirong Chen, Peng Wang, Houlin Zeng and Weixi Chen
    Citation: Lipids in Health and Disease 2012 11:163
    Content type: Research Published on:

  7. Apolipoprotein (Apo) levels are considered more reliable than plasma lipoprotein levels for predicting coronary artery disease (CAD). However, a unanimous Apo marker for CAD has not been identified. In the Chi...

    Authors: Po-Yuan Chang, Chii-Ming Lee, Hsiu-Ching Hsu, Hung-Ju Lin, Kuo-Liong Chien, Ming-Fong Chen, Chu-Huang Chen, Yuan-Teh Lee and Chao-Yuh Yang
    Citation: Lipids in Health and Disease 2012 11:162
    Content type: Research Published on:

  8. Many disorders with plasmalogen deficiency have been reported. Replenishment or replacement of tissue plasmalogens of these disorders would be beneficial to the patients with these disorders, but effects of di...

    Authors: Shiro Mawatari, Toshihiko Katafuchi, Kiyotaka Miake and Takehiko Fujino
    Citation: Lipids in Health and Disease 2012 11:161
    Content type: Research Published on:

  9. Inflammation is increasingly recognized as being of both physiological and pathological importance in the immature brain. Cerebellar pathology occurs in autism, as a neurodevelopmental disorder with genetic an...

    Authors: Afaf El-Ansary and Laila Al-Ayadhi
    Citation: Lipids in Health and Disease 2012 11:160
    Content type: Research Published on:

  11. The babassu palm tree is native to Brazil and is most densely distributed in the Cocais region of the state of Maranhão, in northeastern Brazil. In addition to the industrial use of refined babassu oil, the mi...

    Authors: Maria do Carmo L Barbosa, Eliete Bouskela, Fátima ZGA Cyrino, Ana Paula S Azevedo, Maria Célia P Costa, Maria das Graças C de Souza, Debora S Santos, Felipe L Barbosa, Luiz Felipe A Guerra and Maria do Desterro SB Nascimento
    Citation: Lipids in Health and Disease 2012 11:158
    Content type: Research Published on:

  12. Considering the importance of long chain polyunsaturated fatty acids to fetal development and the lack of studies that have compared the status of fatty acids between adolescents and adults mothers, the purpos...

    Authors: Olívia RC Oliveira, Michelle G Santana, Flávia S Santos, Felipe D Conceição, Fátima LC Sardinha, Glória V Veiga and Maria G Tavares do Carmo
    Citation: Lipids in Health and Disease 2012 11:157
    Content type: Research Published on:

  13. The purpose of this study was to investigate the effects and mechanisms of dihydrotestosterone (DHT)-induced expression of sterol regulatory element binding protein-1 (SREBP-1), and the synthesis and secretion...

    Authors: Bing-rong Zhou, Qiu-hong Huang, Yang Xu, Di Wu, Zhi-qiang Yin and Dan Luo
    Citation: Lipids in Health and Disease 2012 11:156
    Content type: Short report Published on:

  14. Genome wide association studies (GWAS), mostly in Europeans have identified several common variants as associated with key lipid traits. Replication of these genetic effects in South Asian populations is impor...

    Authors: Sajjad Rafiq, Kranthi Kumar M Venkata, Vipin Gupta, DG Vinay, Charles J Spurgeon, Smitha Parameshwaran, Sandeep N Madana, Sanjay Kinra, Liza Bowen, Nicholas J Timpson, George Davey Smith, Frank Dudbridge, Dorairaj Prabhakaran, Yoav Ben-Shlomo, K Srinath Reddy, Shah Ebrahim…
    Citation: Lipids in Health and Disease 2012 11:155
    Content type: Research Published on:

  15. Uncoupling protein 2 (UCP2) was reported to be involved in lipid metabolism through regulating the production of superoxide anion. However, the role of UCP2 in hepatocytes steatosis has not been determined. We...

    Authors: Shuangtao Ma, Dachun Yang, De Li, Yan Tan, Bing Tang and Yongjian Yang
    Citation: Lipids in Health and Disease 2012 11:154
    Content type: Research Published on:

  16. Lipoprotein-associated phospholipase A2 (Lp-PLA2) probably plays an important role in the development of acute coronary syndrome (ACS); elevated levels of Lp-PLA2 are associated with a poorer prognosis in pati...

    Authors: Petr Ostadal, Dagmar Vondrakova, Andreas Kruger, Marek Janotka, Hana Psotova and Miroslav Prucha
    Citation: Lipids in Health and Disease 2012 11:153
    Content type: Short report Published on:

  17. This study investigated the effects of salmonella infection and its chemotherapy on lipid metabolism in tissues of rats infected orally with Salmonella typhimurium and treated intraperitoneally with pefloxacin an...

    Authors: Solomon O Rotimi, David A Ojo, Olusola A Talabi, Elizabeth A Balogun and Oladipo Ademuyiwa
    Citation: Lipids in Health and Disease 2012 11:152
    Content type: Research Published on:

  19. Nitric oxide is a key molecule not only in the cardiovascular system, but also in the metabolic-endocrine system. The purpose of this study was to examine possible associations of the NOS3 T-786C polymorphism (rs...

    Authors: Takahiro Higashibata, Nobuyuki Hamajima, Mariko Naito, Sayo Kawai, Guang Yin, Sadao Suzuki, Yoshikuni Kita, Hideshi Niimura, Takeshi Imaizumi, Keizo Ohnaka, Kokichi Arisawa, Masako Shigeta, Hidemi Ito, Haruo Mikami, Michiaki Kubo, Hideo Tanaka…
    Citation: Lipids in Health and Disease 2012 11:150
    Content type: Research Published on:

  21. Atherosclerosis is a major manifestation of the pathophysiology underlying cardiovascular disease. Flaxseed oil (FO) and α-lipoic acid (LA) have been reported to exert potential benefit to cardiovascular syste...

    Authors: Jiqu Xu, Wei Yang, Qianchun Deng, Qingde Huang, Jin’e Yang and Fenghong Huang
    Citation: Lipids in Health and Disease 2012 11:148
    Content type: Research Published on:

  22. Dietary changes are a major factor in determining cardiovascular risk. n-3 polyunsaturated fatty acids modulate the risk factors for metabolic syndrome via multiple mechanisms, including the regulation of the lip...

    Authors: Adil Haimeur, Lionel Ulmann, Virginie Mimouni, Frédérique Guéno, Fabienne Pineau-Vincent, Nadia Meskini and Gérard Tremblin
    Citation: Lipids in Health and Disease 2012 11:147
    Content type: Research Published on:

  23. Hypertriglyceridemia and postprandial hyperlipidemia is thought to play an important role in atherosclerosis, but to select patients at high-risk for cardiovascular diseases is difficult with triglycerides (TG...

    Authors: Tomoki Nagata, Daisuke Sugiyama, Takako Kise, Satomi Tsuji, Hideo Ohira, Itsuko Sato, Mari Yamamoto, Hitomi Kohsaka, Seiji Kawano, Shizuya Yamashita, Yuichi Ishikawa and Yoshio Fujioka
    Citation: Lipids in Health and Disease 2012 11:146
    Content type: Research Published on:

    The Erratum to this article has been published in Lipids in Health and Disease 2014 13:68

  24. Lipid metabolism is altered in subjects with liver steatosis. FAS is a key enzyme in de novo lipogenesis and both FAS gene expression and enzymatic activity are primarily regulated by metabolic signals in the liv...

    Authors: Maria Notarnicola, Giovanni Misciagna, Valeria Tutino, Marisa Chiloiro, Alberto Ruben Osella, Vito Guerra, Caterina Bonfiglio and Maria Gabriella Caruso
    Citation: Lipids in Health and Disease 2012 11:145
    Content type: Research Published on:

  26. Omega-3 fatty acids are important in treatment of severe primary hypertriglyceridemia (HTG). In 15 patients with severe primary HTG (TG >500 mg/dl despite conventional TG lowering therapy), we assessed efficac...

    Authors: Charles J Glueck, Naseer Khan, Muhammad Riaz, Jagjit Padda, Zia Khan and Ping Wang
    Citation: Lipids in Health and Disease 2012 11:143
    Content type: Research Published on:

  27. Polyunsaturated fatty acids are popular dietary supplements advertised to contribute to weight loss by increasing fat metabolism in liver, but the effects on overall muscle metabolism are less established. We ...

    Authors: Roger A Vaughan, Randi Garcia-Smith, Marco Bisoffi, Carole A Conn and Kristina A Trujillo
    Citation: Lipids in Health and Disease 2012 11:142
    Content type: Research Published on:

  28. The association of rs3757354 single nucleotide polymorphism (SNP) in the E3 ubiquitin ligase myosin regulatory light chain-interacting protein (MYLIP, also known as IDOL) gene and serum lipid levels is not wel...

    Authors: Ting-Ting Yan, Rui-Xing Yin, Qing Li, Ping Huang, Xiao-Na Zeng, Ke-Ke Huang, Dong-Feng Wu and Lynn Htet Htet Aung
    Citation: Lipids in Health and Disease 2012 11:141
    Content type: Research Published on:

  30. Atherosclerosis is a chronic degenerative disease of the arteries and is thought to be one of the most common causes of death globally. In recent years, the functions of adventitial fibroblasts in the developm...

    Authors: Jun Wang, Yanfang Si, Chen Wu, Lu Sun, Yudong Ma, Aili Ge and Baomin Li
    Citation: Lipids in Health and Disease 2012 11:139
    Content type: Research Published on:

  31. Type 2 diabetes mellitus (T2DM) is a chronic disease that is characterized by insulin resistance. Its development is directly connected with the inability of insulin to exert its action, not just on carbohydra...

    Authors: Carla Ribeiro, Lucieli Teresa Cambri, Rodrigo Augusto Dalia, Michel Barbosa de Araújo, José Diego Botezelli, Amanda Christine da Silva Sponton and Maria Alice Rostom de Mello
    Citation: Lipids in Health and Disease 2012 11:138
    Content type: Research Published on:

  32. Partly because of functional genomics, there has been a major paradigm shift from solely thinking of skeletal muscle as contractile machinery to an understanding that it can have roles in paracrine and endocri...

    Authors: Theodore W Zderic and Marc T Hamilton
    Citation: Lipids in Health and Disease 2012 11:137
    Content type: Research Published on:

  33. Surgery is the mainstay therapy for HPV-induced laryngeal papillomatosis (LP) and adjuvant therapies are palliative at best. Research revealed that conjugated-linoleic acid (CLA) may improve the outcome of vir...

    Authors: Louise Louw
    Citation: Lipids in Health and Disease 2012 11:136
    Content type: Research Published on:

  34. Cardiomyocytes apoptosis is an important contributor to myocardial dysfunction and heart failure. Adiponectin has cardioprotective effects, potential mechanisms behind it are not clear in cardiomyocytes. The p...

    Authors: Chuan Dong Wei, Yan Li, Hong Yun Zheng, Kai Sheng Sun, Yong Qing Tong, Wen Dai, Wei Wu and An Yu Bao
    Citation: Lipids in Health and Disease 2012 11:135
    Content type: Research Published on:

  35. The aim of the present study was to evaluate the protective effect of concurrent exercise in the degree of the insulin resistance in mice fed with a high-fat diet, and assess adiponectin receptors (ADIPOR1 and...

    Authors: JM Farias, RM Maggi, CB Tromm, LA Silva, TF Luciano, SO Marques, FS Lira, CT de Souza and RA Pinho
    Citation: Lipids in Health and Disease 2012 11:134
    Content type: Research Published on:

  36. Much attention has been drawn to the deleterious effects of adding progestins to estrogen as hormone therapy (HT) in postmenopausal women. Some widely prescribed progestins have been shown to partially oppose ...

    Authors: Gislaine Casanova and Poli Mara Spritzer
    Citation: Lipids in Health and Disease 2012 11:133
    Content type: Research Published on:

  37. Atherogenic dyslipidemia (AD), defined as low HDL-C plus elevated triglycerides (TG), comorbid to T2DM, increases cardiometabolic risk for CAD even when LDL-C is at target. In T2DM males, AD was shown to corre...

    Authors: Michel P Hermans, Sylvie A Ahn and Michel F Rousseau
    Citation: Lipids in Health and Disease 2012 11:132
    Content type: Research Published on:

  38. Obesity is reaching epidemic worldwide and is risk factor for cardiovascular disease and type 2 diabetes. Although plasma high density lipoprotein (HDL) and apolipoprotein A-I (apoA-I) are inversely correlated...

    Authors: Shuai Wang and Daoquan Peng
    Citation: Lipids in Health and Disease 2012 11:131
    Content type: Review Published on:

  39. Cholesteryl ester transfer protein (CETP) plays a major role in lipid metabolism, but studies on the association of CETP polymorphisms with risks of cardiovascular disease are inconsistent. This study investig...

    Authors: Eliane Soler Parra, Natália Baratella Panzoldo, Denise Kaplan, Helena Coutinho Franco de Oliveira, José Ernesto dos Santos, Luiz Sérgio Fernandes de Carvalho, Andrei Carvalho Sposito, Magnus Gidlund, Ruy Tsutomu Nakamura, Vanessa Helena de Souza Zago, Edna Regina Nakandakare, Eder Carlos Rocha Quintão and Eliana Cotta de Faria
    Citation: Lipids in Health and Disease 2012 11:130
    Content type: Short report Published on:

  40. Flaxseed has recently gained attention in the area of cardiovascular disease primarily because of its rich contents of α-linolenic acid (ALA), lignans, and fiber. Although the benefits of exercise on any singl...

    Authors: Howaida A Nounou, Maha M Deif and Manal A Shalaby
    Citation: Lipids in Health and Disease 2012 11:129
    Content type: Research Published on:

  41. Lipoprotein (a) (Lp [a]) is known being correlated with coronary artery disease (CAD). The SLC22A3-LPAL2-LPA gene cluster, relating with modulating the level of plasma Lp (a), has recently been reported to be ass...

    Authors: Xiaofei Lv, Yuan Zhang, Shaoqi Rao, Fengqiong Liu, Xiaoyu Zuo, Dongfang Su, Min Wang, Min Xia, Honghui Guo, Dan Feng, Changjiang Hong, Dan Li, Wenjun Ma, Ping Ouyang, Xinrui Li, Xiang Feng…
    Citation: Lipids in Health and Disease 2012 11:128
    Content type: Research Published on:

  42. A dietary supplement containing a blend of 170 mg of N-oleyl-phosphatidylethanolamine (NOPE) and 100 mg of epigallocatechin-3-gallate (EGCG) has been shown to improve compliance to low caloric diets. Consideri...

    Authors: Gerald T Mangine, Adam M Gonzalez, Adam J Wells, William P McCormack, Maren S Fragala, Jeffrey R Stout and Jay R Hoffman
    Citation: Lipids in Health and Disease 2012 11:127
    Content type: Research Published on:

  43. The objective of the study is a comparative evaluation of flavone isolated from Mucuna pruriens and coumarin isolated from Ionidium suffruticosum was assessed for the hypolipidemic activity in rats fed with high ...

    Authors: Satheesh Kumar Dharmarajan and Kottai Muthu Arumugam
    Citation: Lipids in Health and Disease 2012 11:126
    Content type: Research Published on:

  44. Visceral fat possesses the most detrimental potential for cardiovascular morbidity through the release of adipokines, as well as metabolic and proinflammatory mediators, which adversely affect metabolic and va...

    Authors: Apostolos Perelas, Vanessa Safarika, Ioannis S Vlachos, Irene Tzanetakou, Laskarina-Maria Korou, Panagiotis Konstantopoulos, Ilias Doulamis, Ioannis Ioannidis, Ioannis Kornezos, Dimitrios Gargas, Christos Klonaris, Despina N Perrea and Achilleas Chatziioannou
    Citation: Lipids in Health and Disease 2012 11:125
    Content type: Short report Published on:

  45. The hydrolysis activities of three alkaline lipases, L-A1, L-A2 and L-A3 secreted by different lipase-producing microorganisms isolated from the Bay of Bohai, P. R. China were characterized with 16 kinds of es...

    Authors: Haikuan Wang, Xiaojie Wang, Xiaolu Li, Yehong Zhang, Yujie Dai, Changlu Guo and Heng Zheng
    Citation: Lipids in Health and Disease 2012 11:124
    Content type: Research Published on:

  46. Although statins (STs) are drugs of first choice in hypercholesterolemic patients, especially in those at high cardiovascular risk, some of them are intolerant to STs or refuse treatment with these drugs. In v...

    Authors: Livia Pisciotta, Antonella Bellocchio and Stefano Bertolini
    Citation: Lipids in Health and Disease 2012 11:123
    Content type: Research Published on:

  47. The effect of an herbal formulation LI85008F on weight loss in obese human subjects was evaluated in an 8-weeks randomized, double-blind, placebo-controlled study (Clinical Trial Registration no. ISRCTN3738170...

    Authors: Krishanu Sengupta, Atmatrana T Mishra, Manikeswar K Rao, Kadainti VS Sarma, Alluri V Krishnaraju and Golakoti Trimurtulu
    Citation: Lipids in Health and Disease 2012 11:122
    Content type: Research Published on:

  48. Periodontal disease is suggested to increase the risk of atherothrombotic disease by inducing dyslipidemia. Recently, we demonstrated that proprotein convertase subtilisin/kexin type 9 (PCSK9), which is known ...

    Authors: Haruna Miyazawa, Koichi Tabeta, Sayuri Miyauchi, Yukari Aoki-Nonaka, Hisanori Domon, Tomoyuki Honda, Takako Nakajima and Kazuhisa Yamazaki
    Citation: Lipids in Health and Disease 2012 11:121
    Content type: Research Published on:

  49. Schisandra, a globally distributed plant, has been widely applied to health care products. Here, we investigated the effects of dietary intake of Fructus Schisandrae chinensis (FSC), both aqueous and ethanolic...

    Authors: Si-Yuan Pan, Qing Yu, Yi Zhang, Xiao-Yan Wang, Nan Sun, Zhi-Ling Yu and Kam-Ming Ko
    Citation: Lipids in Health and Disease 2012 11:120
    Content type: Research Published on:

  50. The single and combined effects of scavenger receptor-BI (SR-BI), ATP-binding cassette transporter (ABC) A1 and G1 on cholesterol efflux from Chinese Hamster Ovary (CHO) cells were investigated.

    Authors: Guohua Song, Chuanlong Zong, Qian Liu, Yanhong Si, Jie Liu, Wei Li, Ping Zhu and Shucun Qin
    Citation: Lipids in Health and Disease 2012 11:118
    Content type: Research Published on:
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Lipids in Health and Disease

ISSN: 1476-511X