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  1. Visceral fat possesses the most detrimental potential for cardiovascular morbidity through the release of adipokines, as well as metabolic and proinflammatory mediators, which adversely affect metabolic and va...

    Authors: Apostolos Perelas, Vanessa Safarika, Ioannis S Vlachos, Irene Tzanetakou, Laskarina-Maria Korou, Panagiotis Konstantopoulos, Ilias Doulamis, Ioannis Ioannidis, Ioannis Kornezos, Dimitrios Gargas, Christos Klonaris, Despina N Perrea and Achilleas Chatziioannou
    Citation: Lipids in Health and Disease 2012 11:125
  2. The hydrolysis activities of three alkaline lipases, L-A1, L-A2 and L-A3 secreted by different lipase-producing microorganisms isolated from the Bay of Bohai, P. R. China were characterized with 16 kinds of es...

    Authors: Haikuan Wang, Xiaojie Wang, Xiaolu Li, Yehong Zhang, Yujie Dai, Changlu Guo and Heng Zheng
    Citation: Lipids in Health and Disease 2012 11:124
  3. Although statins (STs) are drugs of first choice in hypercholesterolemic patients, especially in those at high cardiovascular risk, some of them are intolerant to STs or refuse treatment with these drugs. In v...

    Authors: Livia Pisciotta, Antonella Bellocchio and Stefano Bertolini
    Citation: Lipids in Health and Disease 2012 11:123
  4. The effect of an herbal formulation LI85008F on weight loss in obese human subjects was evaluated in an 8-weeks randomized, double-blind, placebo-controlled study (Clinical Trial Registration no. ISRCTN3738170...

    Authors: Krishanu Sengupta, Atmatrana T Mishra, Manikeswar K Rao, Kadainti VS Sarma, Alluri V Krishnaraju and Golakoti Trimurtulu
    Citation: Lipids in Health and Disease 2012 11:122
  5. Periodontal disease is suggested to increase the risk of atherothrombotic disease by inducing dyslipidemia. Recently, we demonstrated that proprotein convertase subtilisin/kexin type 9 (PCSK9), which is known ...

    Authors: Haruna Miyazawa, Koichi Tabeta, Sayuri Miyauchi, Yukari Aoki-Nonaka, Hisanori Domon, Tomoyuki Honda, Takako Nakajima and Kazuhisa Yamazaki
    Citation: Lipids in Health and Disease 2012 11:121
  6. Schisandra, a globally distributed plant, has been widely applied to health care products. Here, we investigated the effects of dietary intake of Fructus Schisandrae chinensis (FSC), both aqueous and ethanolic...

    Authors: Si-Yuan Pan, Qing Yu, Yi Zhang, Xiao-Yan Wang, Nan Sun, Zhi-Ling Yu and Kam-Ming Ko
    Citation: Lipids in Health and Disease 2012 11:120
  7. Advanced stages of leprosy show T cell unresponsiveness and lipids of mycobacterial origin are speculated to modulate immune responses in these patients. Present study elucidates the role of phenolicglycolipid...

    Authors: Pradeep Kumar Dagur, Bhawna Sharma, Rajni Upadhyay, Bhavyata Dua, Arshad Rizvi, Naim Akhtar Khan, Vishwa Mohan Katoch, Utpal Sengupta and Beenu Joshi
    Citation: Lipids in Health and Disease 2012 11:119
  8. The single and combined effects of scavenger receptor-BI (SR-BI), ATP-binding cassette transporter (ABC) A1 and G1 on cholesterol efflux from Chinese Hamster Ovary (CHO) cells were investigated.

    Authors: Guohua Song, Chuanlong Zong, Qian Liu, Yanhong Si, Jie Liu, Wei Li, Ping Zhu and Shucun Qin
    Citation: Lipids in Health and Disease 2012 11:118
  9. Several studies have identified use of non-steroidal-anti-inflammatory drugs and statins for prevention of dementia, but their efficacy in slowing progression is not well understood. Cerebrovascular disturbanc...

    Authors: Menuka Pallebage-Gamarallage, Virginie Lam, Ryusuke Takechi, Susan Galloway, Karin Clark and John Mamo
    Citation: Lipids in Health and Disease 2012 11:117
  10. Omega-3 poly-unsaturated fatty acids (ω-3 PUFAs) have demonstrated to be beneficial in the prevention of cardiovascular disease, however, the mechanisms by which they perform their cardiovascular protection ha...

    Authors: Elena Burillo, Rocío Mateo-Gallego, Ana Cenarro, Sarah Fiddyment, Ana M Bea, Inmaculada Jorge, Jesús Vázquez and Fernando Civeira
    Citation: Lipids in Health and Disease 2012 11:116
  11. Inflammation and increased ceramide concentrations characterise adipose tissue of obese women with high liver fat content compared to equally obese women with normal liver fat content. The present study charac...

    Authors: Maria Kolak, Joanna Gertow, Jukka Westerbacka, Scott A Summers, Jan Liska, Anders Franco-Cereceda, Matej Orešič, Hannele Yki-Järvinen, Per Eriksson and Rachel M Fisher
    Citation: Lipids in Health and Disease 2012 11:115
  12. Previous studies showed that intake of yacon or some lactic acid bacteria was able to inhibit the development of diabetes mellitus, by reducing glucose and associated symptoms, for example, the lipid profile.

    Authors: Mariana N Roselino, Nadiége D Pauly-Silveira, Daniela CU Cavallini, Larissa S Celiberto, Roseli A Pinto, Regina C Vendramini and Elizeu A Rossi
    Citation: Lipids in Health and Disease 2012 11:114
  13. Milk contains numerous nutrients. The content of n-3 fatty acids, the n-6/n-3 ratio, and short- and medium-chain fatty acids may promote positive health effects. In Western societies, cow’s milk fat is perceiv...

    Authors: Giovanni Martemucci and Angela Gabriella D’Alessandro
    Citation: Lipids in Health and Disease 2012 11:113
  14. Fucoxanthin is a xanthophyll present in brown seaweeds and has several beneficial effects, including anti-obesity and anti-diabetic effects. However, we and another group previously observed that fucoxanthin i...

    Authors: Fumiaki Beppu, Masashi Hosokawa, Yoshimi Niwano and Kazuo Miyashita
    Citation: Lipids in Health and Disease 2012 11:112
  15. It is known that the increased level of IDL and oxidized LDL are associated with risk of cardiovascular disease, and the lipoprotein abnormalities accelerate atherosclerosis. Cardiovascular disease is a major ...

    Authors: Yuji Hirowatari, Yasuhiko Homma, Joe Yoshizawa and Koichiro Homma
    Citation: Lipids in Health and Disease 2012 11:111
  16. The interactions of oxidized low-density lipoprotein (LDL) and macrophages are hallmarks in the development of atherosclerosis. The biological activities of the modified particle in these cells are due to the ...

    Authors: Ute Stemmer, Zsuzsanna A Dunai, Daniel Koller, Gabriel Pürstinger, Elfriede Zenzmaier, Hans P Deigner, Elma Aflaki, Dagmar Kratky and Albin Hermetter
    Citation: Lipids in Health and Disease 2012 11:110
  17. Brain-derived neurotrophic factor (BDNF) is a potent neurotrophic factor that is implicated in the regulation of food intake and body weight. Polyunsaturated fatty acids (PUFAs) localised in cell membranes hav...

    Authors: Umashankar Vetrivel, Sathya Baarathi Ravichandran, Kaviarasan Kuppan, Jithu Mohanlal, Undurti Narasimha Das and Angayarkanni Narayanasamy
    Citation: Lipids in Health and Disease 2012 11:109
  18. Ingestion of glucosylceramide improves transepidermal water loss (TEWL) from the skin, but the underlying mechanism by which a small amount of dietary glucosylceramide can vastly improve skin conditions remain...

    Authors: Yoshiyuki Shirakura, Kanako Kikuchi, Kenji Matsumura, Katsuyuki Mukai, Susumu Mitsutake and Yasuyuki Igarashi
    Citation: Lipids in Health and Disease 2012 11:108
  19. To compare the predictive ability of adolescent lipoprotein classification using the National Examination Survey (NHANES) cut points and those of the National Cholesterol Education Program (NCEP) for predictin...

    Authors: Masumeh Hatami, Maryam Tohidi, Reza Mohebi, Davood Khalili, Fereidoun Azizi and Farzad Hadaegh
    Citation: Lipids in Health and Disease 2012 11:107
  20. Adiponectin is reported to relate with cardiovascular diseases, we sought to examine whether adiponectin is associated with disease progression of heart failure from hypertension in rats in comparison with oth...

    Authors: Mingqiang Fu, Jingmin Zhou, Juying Qian, Xuejuan Jin, Hongmin Zhu, Chunlin Zhong, Michael Fu, Yunzeng Zou and Junbo Ge
    Citation: Lipids in Health and Disease 2012 11:106
  21. Epidemiological studies have suggested the benefits of omega-3 polyunsaturated fatty acids (n-3 PUFAs) on cardiovascular health, but only limited data are available describing n-3 PUFA regulated pathways in hu...

    Authors: Simone Schmidt, Frank Stahl, Kai-Oliver Mutz, Thomas Scheper, Andreas Hahn and Jan P Schuchardt
    Citation: Lipids in Health and Disease 2012 11:105
  22. Since the amounts of arachidonic acid (AA) and EPA in food may have implications for human health, we investigated whether a small change in chicken feed influenced the blood lipid concentration in humans inge...

    Authors: Anna Haug, Nicole F Nyquist, Therese J Mosti, Malin Andersen and Arne T Høstmark
    Citation: Lipids in Health and Disease 2012 11:104
  23. The aim of the present study was to appraise the antimicrobial activity of Ricinus communis L. essential oil against different pathogenic microorganisms and the cytotoxic activity against HeLa cell lines.

    Authors: Zied Zarai, Ines Ben Chobba, Riadh Ben Mansour, Ahmed Békir, Néji Gharsallah and Adel Kadri
    Citation: Lipids in Health and Disease 2012 11:102
  24. Metabolic syndrome (MetS) is an important health problem which puts individuals at risk for cardiovascular diseases and type 2 diabetes as well as obesity-related cancers such as colon and renal cell in men, a...

    Authors: Fareed K N Arthur, Michael Adu-Frimpong, James Osei-Yeboah, Faustina O Mensah and Lawrence Owusu
    Citation: Lipids in Health and Disease 2012 11:101
  25. Although most of what is known about the biology and function of arachidonic acid metabolites comes from the study of mammalian biology, these compounds can also be produced by lower eukaryotes, including yeas...

    Authors: Ruan Ells, Johan LF Kock, Jacobus Albertyn and Carolina H Pohl
    Citation: Lipids in Health and Disease 2012 11:100
  26. The purpose of the present study was to evaluate the relationship between sleep duration and dietary habits in elderly obese patients treated at an institute of cardiology.

    Authors: Aline Alves Santana, Gustavo Duarte Pimentel, Monica Romualdo, Lila Missae Oyama, Ronaldo Vagner Thomatieli Santos, Ricardo Aurino Pinho, Claudio Teodoro de Souza, Bruno Rodrigues, Erico Chagas Caperuto and Fabio Santos Lira
    Citation: Lipids in Health and Disease 2012 11:99
  27. Pentacyclic triterpenes in general exert beneficial effects in metabolic disorders. This study investigated the effects of α, β-amyrin, a pentacyclic triterpene mixture from the resin of Protium heptaphyllum on b...

    Authors: Flávia Almeida Santos, Julyanne Torres Frota, Bruno Rodrigues Arruda, Tiago Sousa de Melo, Armenio André de Carvalho Almeida da Silva, Gerly Anne de Castro Brito, Mariana Helena Chaves and Vietla Satyanarayana Rao
    Citation: Lipids in Health and Disease 2012 11:98
  28. Several genetic polymorphisms have been reported to modify the effects of smoking on serum lipid levels. The objective of this study was to investigate whether longevity-associated mitochondrial DNA 5178 (Mt51...

    Authors: Akatsuki Kokaze, Mamoru Ishikawa, Naomi Matsunaga, Kanae Karita, Masao Yoshida, Naoki Shimada, Tadahiro Ohtsu, Takako Shirasawa, Hirotaka Ochiai, Masao Satoh, Masayasu Hashimoto, Hiromi Hoshino and Yutaka Takashima
    Citation: Lipids in Health and Disease 2012 11:97
  29. Stem/progenitor cell-based therapy has successfully been used as a novel therapeutic strategy for vascular diseases triggered by endothelial dysfunction. The aim of this study was to investigate the effects of...

    Authors: Leandro C F Lima, Marcella L Porto, Bianca P Campagnaro, Clarissa L Tonini, Breno V Nogueira, Thiago MC Pereira, Elisardo C Vasquez and Silvana S Meyrelles
    Citation: Lipids in Health and Disease 2012 11:96
  30. Saury oil contains considerable amounts of n-3 polyunsaturated fatty acids (PUFA) and monounsaturated fatty acids (MUFA) with long aliphatic tails (>18C atoms). Ingestion of saury oil reduces the risk of devel...

    Authors: Zhi-Hong Yang, Hiroko Miyahara, Jiro Takeo and Masashi Katayama
    Citation: Lipids in Health and Disease 2012 11:95

    The Erratum to this article has been published in Lipids in Health and Disease 2012 11:151

  31. Cigarette smoking had been confirmed as an increased risk for dyslipidemia, but none of the evidence was from long-lived population. In present study, we detected relationship between cigarette smoking habits ...

    Authors: Zhang Yan-Ling, Zhao Dong-Qing, Huang Chang-Quan and Dong Bi-Rong
    Citation: Lipids in Health and Disease 2012 11:94
  32. This study aimed at investigating the oxidative stress ameliorating effect, lipids profile restoration, and the anti-inflammatory effect of Samsum Ant Venom (SAV) in induced endotoxemic male rats, injected wit...

    Authors: Hossam Ebaid, Mohamed Al-Khalifa, Ahmed M Isa and Saad Gadoa
    Citation: Lipids in Health and Disease 2012 11:93
  33. The relationships between fat mass and bone tissue are complex and not fully elucidated. A high-fat/high-sucrose diet has been shown to induce harmful effects on bone micro architecture and bone biomechanics o...

    Authors: Maude Gerbaix, Lore Metz, Fabrice Mac-Way, Cédric Lavet, Christelle Guillet, Stéphane Walrand, Aurélie Masgrau, Marie-Thérèse Linossier, Laurence Vico and Daniel Courteix
    Citation: Lipids in Health and Disease 2012 11:91
  34. Diabetic retinopathy is a major complication of dysregulated hyperglycemia. Retinal vascular endothelial cell dysfunction is an early event in the pathogenesis of diabetic retinopathy. Studies showed that hype...

    Authors: Junhui Shen, Shengrong Shen, Undurti N Das and Guotong Xu
    Citation: Lipids in Health and Disease 2012 11:90
  35. Tangier disease (TD) is a phenotypic expression of rare familial syndrome with mutations in the ABCA1 transporter. The risk of coronary artery disease in patients with TD is variable. On the other hand the piv...

    Authors: Vana Kolovou, Vasiliki D Papakonstantinou, George Stamatakis, Sophia N Verouti, Marianna N Xanthopoulou, Genovefa Kolovou and Constantinos A Demopoulos
    Citation: Lipids in Health and Disease 2012 11:89
  36. The erythrocyte membrane lesion is a serious diabetic complication. A number of studies suggested that n-3 fatty acid could reduce lipid peroxidation and elevate α- or γ-tocopherol contents in membrane of eryt...

    Authors: Wei Yang, Juan Fu, Miao Yu, Qingde Huang, Di Wang, Jiqu Xu, Qianchun Deng, Ping Yao, Fenghong Huang and Liegang Liu
    Citation: Lipids in Health and Disease 2012 11:88
  37. Fluorescence-based cell-free assays offer an attractive alternative to current cell-based assays for measuring the redox activity of High-Density Lipoprotein (HDL). We have recently developed a biochemical ass...

    Authors: Theodoros Kelesidis, Srinivasa T Reddy, Diana Huynh, David Meriwether, Alan M Fogelman, Mohamad Navab and Otto O Yang
    Citation: Lipids in Health and Disease 2012 11:87
  38. The study was undertaken to examine the effects of berberine (BBR) on serum homocysteine, lipids and the aortic lesion in Sprague–Dawley (SD) rats fed with a long-term high-fat diet (HFD).

    Authors: Xin-xia Chang, Hong-mei Yan, Qiong Xu, Ming-feng Xia, Hua Bian, Teng-fang Zhu and Xin Gao
    Citation: Lipids in Health and Disease 2012 11:86
  39. Oxidized low density lipoprotein (ox-LDL), a risk factor of atherosclerosis, facilitates the formation and vulnerability of atherosclerotic plaque, thus contributing to several clinical complications. Stem cel...

    Authors: Hui Yang, Ahmed Salah Salem Mohamed and Sheng-hua Zhou
    Citation: Lipids in Health and Disease 2012 11:85
  40. The biodiversity of the marine environment and the associated chemical diversity constitute a practically unlimited source of new active substances in the field of the development of bioactive products. In our...

    Authors: Yosra Ayed, Manel Bousabbeh, Hazem Ben Mabrouk, Maram Morjen, Naziha Marrakchi and Hassen Bacha
    Citation: Lipids in Health and Disease 2012 11:84
  41. A recent study investigated the MYLIP region in the Mexican population in order to fine-map the actual susceptibility variants of this locus. The p.N342S polymorphism was identified as the underlying functional v...

    Authors: Paulo C J L Santos, Theo G M Oliveira, Pedro A Lemos, José G Mill, José E Krieger and Alexandre C Pereira
    Citation: Lipids in Health and Disease 2012 11:83
  42. Excess peroxisome proliferator-activated receptor (PPAR) stimulation has been associated with detrimental health effects including impaired myocardial function. Recently, supplementation with n-3 polyunsaturat...

    Authors: Elin Strand, Bodil Bjorndal, Ottar Nygard, Lena Burri, Christ Berge, Pavol Bohov, Bjørn J Christensen, Kjetil Berge, Hege Wergedahl, Asgaut Viste and Rolf K Berge
    Citation: Lipids in Health and Disease 2012 11:82
  43. Rose-scented geranium (Pelargonium graveolens L’Hér.), which is used in traditional Tunisian folk medicine for the treatment of hyperglycaemia, is widely known as one of the medicinal herbs with the highest antio...

    Authors: Maher Boukhris, Mohamed Bouaziz, Ines Feki, Hedya Jemai, Abdelfattah El Feki and Sami Sayadi
    Citation: Lipids in Health and Disease 2012 11:81
  44. A sedentary lifestyle predisposes to cardiometabolic diseases. Lifestyle changes such as increased physical activity improve a range of cardiometabolic risk factors. The objective of this study was to examine ...

    Authors: Per Sjögren, Justo Sierra-Johnson, Lena V Kallings, Tommy Cederholm, Maria Kolak, Mats Halldin, Kerstin Brismar, Ulf de Faire, Mai-Lis Hellénius and Rachel M Fisher
    Citation: Lipids in Health and Disease 2012 11:80
  45. There is a relationship among hypercholesterolemia, oxidative stress and inflammation in the atherogenesis. Thus, the objective of the present study was to assess paraoxonase (PON1), superoxide dismutase (SOD)...

    Authors: Paula Rossini Augusti, Amanda Roggia Ruviaro, Andréia Quatrin, Sabrina Somacal, Greicy Michelle Marafiga Conterato, Juliana Tanara Vicentini, Marta Medeiros Frescura Duarte and Tatiana Emanuelli
    Citation: Lipids in Health and Disease 2012 11:79
  46. The main purpose of this research was to investigate the alterations in the aerobic capacity and appearance of metabolic alterations in Wistar rats fed on fructose-rich diet. We separated twenty-eight rats int...

    Authors: José Diego Botezelli, Lucieli Teresa Cambri, Ana Carolina Ghezzi, Rodrigo Augusto Dalia, Fabrício Azevedo Voltarelli and Maria Alice Rostom de Mello
    Citation: Lipids in Health and Disease 2012 11:78
  47. Cardiovascular disease (CVD) is the number one cause of mortality worldwide and a low high-density lipoprotein cholesterol (HDL-C) level is an important marker of CVD risk. Garlic (Allium sativum) has been widely...

    Authors: Seohyun Lee, Hyunjin Joo, Chong-Tai Kim, In-Hwan Kim and Yangha Kim
    Citation: Lipids in Health and Disease 2012 11:77
  48. Resynthesis of triglycerides in enterocytes of the small intestine plays a critical role in the absorption of dietary fat. Acyl-CoA:monoacylglycerol acyltransferase-2 (MGAT2) is highly expressed in the small i...

    Authors: Takuma Tsuchida, Sayaka Fukuda, Hisanori Aoyama, Nobuhiko Taniuchi, Tomomi Ishihara, Noriko Ohashi, Hiroko Sato, Koji Wakimoto, Masaharu Shiotani and Akira Oku
    Citation: Lipids in Health and Disease 2012 11:75

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