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  1. A sedentary lifestyle increases the risk of developing cardiovascular disease, obesity, and diabetes. This phenomenon is supported by recent studies suggesting a chronic, low-grade inflammation status. Endotox...

    Authors: Fabio S Lira, Jose C Rosa, Gustavo D Pimentel, Hélio A Souza, Erico C Caperuto, Luiz C Carnevali Jr, Marília Seelaender, Ana R Damaso, Lila M Oyama, Marco T de Mello and Ronaldo V Santos
    Citation: Lipids in Health and Disease 2010 9:82
    Content type: Research Published on:

  2. The metabolic syndrome, known also as the insulin resistance syndrome, refers to the clustering of several risk factors for atherosclerotic cardiovascular disease. Dyslipidaemia is a hallmark of the syndrome a...

    Authors: Chia Hui Apphia Eu, Wai Yen Alfred Lim, So Ha Ton and Khalid bin Abdul Kadir
    Citation: Lipids in Health and Disease 2010 9:81
    Content type: Research Published on:

  3. Treatment guidelines recommend LDL-C as the primary target of therapy in patients with hypercholesterolemia. Moreover, combination therapies with lipid-lowering drugs that have different mechanisms of action a...

    Authors: Carlo M Rotella, Augusto Zaninelli, Cristina Le Grazie, Mary E Hanson and Gian Franco Gensini
    Citation: Lipids in Health and Disease 2010 9:80
    Content type: Research Published on:

  4. We have recently noted that ingestion of dietary lipid (in the form of heavy whipping cream) leads to greater oxidative stress than dietary carbohydrate (in the form of dextrose), when consumed in isocaloric a...

    Authors: Richard J Bloomer, Mohammad M Kabir, Kate E Marshall, Robert E Canale and Tyler M Farney
    Citation: Lipids in Health and Disease 2010 9:79
    Content type: Research Published on:

  6. Dietary 1(3)-behenoyl-2,3(1)-dioleoyl-rac-glycerol (BOO) has been reported to inhibit pancreatic lipase activity in vitro and suppress postprandial hypertriacylglycerolemia in humans. In the present study, the an...

    Authors: Makiko Kojima, Nobuhiko Tachibana, Takashi Yamahira, Satoshi Seino, Ayako Izumisawa, Nobuo Sagi, Toshiharu Arishima, Mitsutaka Kohno, Kiyoharu Takamatsu, Motohiko Hirotsuka and Ikuo Ikeda
    Citation: Lipids in Health and Disease 2010 9:77
    Content type: Research Published on:

  7. The weakening of the cardiovascular system associated with aging could be countered by increasing levels of physical activity and functional fitness. However, inconsistent findings have been found, and the var...

    Authors: Raul A Martins, Manuel T Veríssimo, Manuel J Coelho e Silva, Sean P Cumming and Ana M Teixeira
    Citation: Lipids in Health and Disease 2010 9:76
    Content type: Research Published on:

  8. The risk of cardiovascular disease is inversely correlated to level of plasma HDL-c. Moreover, reverse cholesterol transport (RCT) from peripheral tissues to the liver is the most widely accepted mechanism lin...

    Authors: Karima Bencharif, Laurence Hoareau, Ravi K Murumalla, Evelyne Tarnus, Frank Tallet, Roger G Clerc, Christophe Gardes, Maya Cesari and Régis Roche
    Citation: Lipids in Health and Disease 2010 9:75
    Content type: Research Published on:

  9. Frog skin has been sequentially and scientifically evaluated by our group for its wound healing efficiency. Owing to the complex structure of skin, attempts were being made to analyse the role of individual co...

    Authors: Venkat Raghavan K, Mary Babu, Rama Rajaram and Korrapati Purna Sai
    Citation: Lipids in Health and Disease 2010 9:74
    Content type: Research Published on:

  10. Lipid-enriched diets and oxidative stress are risk factors for the development of atherosclerosis. The effects of the methanolic (ME) and cyclohexane (CHE) extracts of the Pistacia vera nut, often included in the...

    Authors: Katerina A Marinou, Katerina Georgopoulou, George Agrogiannis, Theodore Karatzas, Dimitrios Iliopoulos, Apostolos Papalois, Achilles Chatziioannou, Prokopios Magiatis, Maria Halabalaki, Nektaria Tsantila, Leandros A Skaltsounis, Efstratios Patsouris and Ismene A Dontas
    Citation: Lipids in Health and Disease 2010 9:73
    Content type: Research Published on:

  11. In the present investigation we compared blood epinephrine (EPI), norepinephrine (NE), free fatty acids (FFA) and glycerol concentrations in response to a capsaicinoid supplement or placebo in healthy adults b...

    Authors: Richard J Bloomer, Robert E Canale, Sid Shastri and Sujata Suvarnapathki
    Citation: Lipids in Health and Disease 2010 9:72
    Content type: Research Published on:

  12. Intensive statin therapy decreases mortality and incidence of coronary events in patients after acute coronary syndrome (ACS). Recently it has been reported that spontaneous lipid levels remain clinically stab...

    Authors: Dagmar Vondrakova, Petr Ostadal and Andreas Kruger
    Citation: Lipids in Health and Disease 2010 9:71
    Content type: Research Published on:

  13. Nutritional control of gene regulation guides the transformation of smooth muscle cells (SMC) into foam cells in atherosclerosis. Oxidative stress has been reported in areas of lipid accumulation, activating p...

    Authors: Sonia Perales, Ma José Alejandre, Rogelio Palomino Morales, Carolina Torres and Ana Linares
    Citation: Lipids in Health and Disease 2010 9:70
    Content type: Research Published on:

  14. To evaluate the relationship between the low-density lipoprotein cholesterol (LDL-C)/high-density lipoprotein cholesterol (HDL-C) ratio and HDL subclass distribution and to further examine and discuss the pote...

    Authors: Li Tian, Yinghui Liu, Yang Qin, Shiyin Long, Yanhua Xu and Mingde Fu
    Citation: Lipids in Health and Disease 2010 9:69
    Content type: Research Published on:

  15. It was investigated whether dietary polyunsaturated fatty acids (PUFA) could influence colonic injury, tissue DNA damage, cytokines and myeloperoxidase activity (MPO) and plasma corticosterone in DSS-induced c...

    Authors: Karina V Barros, Roberta AN Xavier, Gilclay G Abreu, Carlos AR Martinez, Marcelo L Ribeiro, Alessandra Gambero, Patrícia O Carvalho, Claudia MO Nascimento and Vera LF Silveira
    Citation: Lipids in Health and Disease 2010 9:68
    Content type: Research Published on:

  17. Poor control of blood pressure leads to hypertension which is a major risk factor for development of cardiovascular disease. The present study aimed to explore possible mechanisms of elevation in blood pressur...

    Authors: Xin-Fang Leong, Mohd Rais Mustafa, Srijit Das and Kamsiah Jaarin
    Citation: Lipids in Health and Disease 2010 9:66
    Content type: Research Published on:

  18. Experimental evidences demonstrate that vegetable derived extracts inhibit cholesterol absorption in the gastrointestinal tract. To further explore the mechanisms behind, we modeled duodenal contents with seve...

    Authors: Mariona Jové, José CE Serrano, Maria Josep Bellmunt, Anna Cassanyé, Neus Anglès, Jordi Reguant, José R Morelló, Reinald Pamplona and Manuel Portero-Otín
    Citation: Lipids in Health and Disease 2010 9:65
    Content type: Research Published on:

  19. Recent studies have shown that dietary red palm oil (RPO) supplementation improves functional recovery following ischaemia/reperfusion in isolated hearts. The main aim of this study was to investigate the effe...

    Authors: Dirk J Bester, Krisztina Kupai, Tamas Csont, Gergu Szucs, Csaba Csonka, Adriaan J Esterhuyse, Peter Ferdinandy and Jacques Van Rooyen
    Citation: Lipids in Health and Disease 2010 9:64
    Content type: Research Published on:

  21. Disrupted cholesterol regulation leading to increased circulating and membrane cholesterol levels is implicated in many age-related chronic diseases such as cardiovascular disease (CVD), Alzheimer's disease (A...

    Authors: Rishikesh Mankidy, Pearson WK Ahiahonu, Hong Ma, Dushmanthi Jayasinghe, Shawn A Ritchie, Mohamed A Khan, Khine K Su-Myat, Paul L Wood and Dayan B Goodenowe
    Citation: Lipids in Health and Disease 2010 9:62
    Content type: Research Published on:

  22. Cholesterol deposition in arterial wall drives atherosclerosis. The key goal of this study was to examine the relationship between plaque cholesterol content and patient characteristics that typically associat...

    Authors: Zhu Chen, Marina Ichetovkin, Marc Kurtz, Emanuel Zycband, Douglas Kawka, John Woods, Xuanmin He, Andrew S Plump and Eric Hailman
    Citation: Lipids in Health and Disease 2010 9:61
    Content type: Research Published on:

  23. The expression of some genes controlling energy homeostasis could be regulated by epigenetic mechanisms that may play a role in body weight regulation. Thus, it is known that various nutritional factors affect...

    Authors: Almudena Lomba, Fermín I Milagro, Diego F García-Díaz, Amelia Marti, Javier Campión and J Alfredo Martínez
    Citation: Lipids in Health and Disease 2010 9:60
    Content type: Research Published on:

  24. phospholipid transfer protein (PLTP) plays important roles in lipoprotein metabolism and atherosclerosis and is expressed by macrophages and macrophage foam cells (MFCs). The aim of the present study was to de...

    Authors: Marius R Robciuc, Jari Metso, Anca Sima, Christian Ehnholm and Matti Jauhiainen
    Citation: Lipids in Health and Disease 2010 9:59
    Content type: Research Published on:

  25. To describe the lipid profile of women prior to, during and after pregnancy and to assess the effect of consecutive pregnancies on the plasma lipid profile.

    Authors: David Mankuta, Matan Elami-Suzin, Asher Elhayani and Shlomo Vinker
    Citation: Lipids in Health and Disease 2010 9:58
    Content type: Research Published on:

  27. Cytoplasmic lipid-droplets are common inclusions of eukaryotic cells. Lipid-droplet binding thalidomide analogs (2,6-dialkylphenyl-4/5-amino-substituted-5,6,7-trifluorophthalimides) with potent anticancer acti...

    Authors: László G Puskás, Liliána Z Fehér, Csaba Vizler, Ferhan Ayaydin, Erzsébet Rásó, Eszter Molnár, István Magyary, Iván Kanizsai, Márió Gyuris, Ramóna Madácsi, Gabriella Fábián, Klaudia Farkas, Péter Hegyi, Ferenc Baska, Béla Ózsvári and Klára Kitajka
    Citation: Lipids in Health and Disease 2010 9:56
    Content type: Research Published on:

  28. Forearm blood flow responses during mental stress are greater in individuals homozygous for the Glu27 allele. A high-fat meal is associated with impaired endothelium-dependent dilatation. We investigated the i...

    Authors: Marcia MG Gowdak, Mateus C Laterza, Maria Urbana PB Rondon, Ivani C Trombetta, Alexandre C Pereira, José Eduardo Krieger and Carlos Eduardo Negrão
    Citation: Lipids in Health and Disease 2010 9:55
    Content type: Research Published on:

  29. This study compared LDL, HDL, and VLDL subclasses in overweight or obese adults consuming either a reduced carbohydrate (RC) or reduced fat (RF) weight maintenance diet for 9 months following significant weigh...

    Authors: James D LeCheminant, Bryan K Smith, Eric C Westman, Mary C Vernon and Joseph E Donnelly
    Citation: Lipids in Health and Disease 2010 9:54
    Content type: Short paper Published on:

  30. Our aim was to evaluate the effects of soybean oil treatment for 15 days on arterial and ventricular pressure, myocardial mechanics and proteins involved in calcium handling.

    Authors: Rogério Faustino Ribeiro Junior, Aurélia Araújo Fernandes, Eduardo Frizzera Meira, Priscila Rossi Batista, Fabiana Dayse Magalhães Siman, Dalton Valentim Vassallo, Alessandra Simão Padilha and Ivanita Stefanon
    Citation: Lipids in Health and Disease 2010 9:53
    Content type: Research Published on:

  31. The Friedewald formula (FF) is useful for calculating serum low-density lipoprotein cholesterol (LDL-C) values, but has a remarkable deviation and limitation especially in hypertriglyceridemia. We modify the f...

    Authors: Yunqin Chen, Xiaojin Zhang, Baishen Pan, Xuejuan Jin, Haili Yao, Bin Chen, Yunzeng Zou, Junbo Ge and Haozhu Chen
    Citation: Lipids in Health and Disease 2010 9:52
    Content type: Short paper Published on:

  32. The effects of hypercholesterolemia on vasomotricity in apolipoprotein E-deficient (ApoE) mice, a murine model of spontaneous atherosclerosis, are still unclear. The studies were mostly performed in conductanc...

    Authors: Maine S Cola, Agata L Gava, Silvana S Meyrelles and Elisardo C Vasquez
    Citation: Lipids in Health and Disease 2010 9:51
    Content type: Short paper Published on:

  33. Oxidative stress is supposed to increase lipid accumulation by stimulation of hepatic lipogenesis at transcriptional level. This study was performed to investigate the role of glutathione in the regulation of ...

    Authors: Corinna Brandsch, Tobias Schmidt, Diana Behn, Kristin Weiße, Andreas S Mueller and Gabriele I Stangl
    Citation: Lipids in Health and Disease 2010 9:50
    Content type: Research Published on:

  34. The novel compound 1a is one of the isoflavone fatty acid esters. In order to investigate the anti-obesity effect of compound 1a and its potential mechanism of influence in adipocyte differentiation, Obese male C...

    Authors: Yao Yao, Xiao-Bo Li, Wei Zhao, Yan-Yan Zeng, Hong Shen, Hua Xiang and Hong Xiao
    Citation: Lipids in Health and Disease 2010 9:49
    Content type: Research Published on:

  35. Apolipoprotein B (apoB) containing lipoproteins, i.e. VLDL, LDL and Lp(a), are consequently lowered by ACTH treatment in humans. This is also seen as reduced plasma apoB by 20-30% and total cholesterol by 30-4...

    Authors: Maria Skoog, Maria Berggren-Söderlund, Peter Nilsson-Ehle and Ning Xu
    Citation: Lipids in Health and Disease 2010 9:48
    Content type: Research Published on:

  36. Endocannabinoids (eCBs) are ubiquitous lipid mediators that act on specific (CB1, CB2) and non-specific (TRPV1, PPAR) receptors. Despite many experimental animal studies proved eCB involvement in the pathogene...

    Authors: Marcello Naccarato, Daniela Pizzuti, Stefania Petrosino, Marco Simonetto, Laura Ferigo, Fabio Chiodo Grandi, Gilberto Pizzolato and Vincenzo Di Marzo
    Citation: Lipids in Health and Disease 2010 9:47
    Content type: Research Published on:

  37. Paraoxonase-1 (PON1), a lactonase synthesized by the liver, circulates in blood bound to high-density lipoproteins (HDL). This enzyme is thought to degrade oxidized phospholipids and play an important role in ...

    Authors: Judit Marsillach, Gerard Aragonès, Bharti Mackness, Michael Mackness, Anna Rull, Raúl Beltrán-Debón, Juan Pedro-Botet, Carlos Alonso-Villaverde, Jorge Joven and Jordi Camps
    Citation: Lipids in Health and Disease 2010 9:46
    Content type: Research Published on:

  38. The body mass index (BMI) is the most commonly used marker for evaluating obesity related risks, however, central obesity measures have been proposed to be more informative. Lipid accumulation product (LAP) is...

    Authors: Mohammadreza Bozorgmanesh, Farzad Hadaegh and Fereidoun Azizi
    Citation: Lipids in Health and Disease 2010 9:45
    Content type: Research Published on:

  39. Piper sarmentosum (P.s) has flavonoid component in its leaves which has antioxidative effect. To date, its effect on atherosclerosis has not been studied histologically.

    Authors: Adel A Amran, Zaiton Zakaria, Faizah Othman, Srijit Das, Santhana Raj and Nor-Anita M M Nordin
    Citation: Lipids in Health and Disease 2010 9:44
    Content type: Research Published on:

  40. The endocannabinoids, anandamide and 2-AG, are produced by adipocytes, where they stimulate lipogenesis via cannabinoid CB1 receptors and are under the negative control of leptin and insulin. Endocannabinoid leve...

    Authors: Giovanni Annuzzi, Fabiana Piscitelli, Lucrezia Di Marino, Lidia Patti, Rosalba Giacco, Giuseppina Costabile, Lutgarda Bozzetto, Gabriele Riccardi, Roberta Verde, Stefania Petrosino, Angela A Rivellese and Vincenzo Di Marzo
    Citation: Lipids in Health and Disease 2010 9:43
    Content type: Research Published on:

  42. In this study we aimed to assess lipid peroxidation during carotid endarterectomy by the formation of PUFA hydroperoxides (PUFAHP) and isoprostanes (IP) and concomitant peroxisomal beta-oxidation as a physiolo...

    Authors: Sebastiano Banni, Roberto Montisci, Roberto Sanfilippo, Gabriele Finco, Daniela Sanna, Elena Giordano, Elisabetta Murru, Lina Cordeddu, Gianfranca Carta, Donata Banni and Antonio Marchi
    Citation: Lipids in Health and Disease 2010 9:41
    Content type: Research Published on:

  44. There are many reports about the anti-arrhythmic effects of ω-3 polyunsaturated fatty acids, however, the mechanisms are still not completely delineated. The purpose of this study was to investigate the charac...

    Authors: Ru-xing Wang, Xiao-rong Li, Tao Guo, Li-ping Sun, Su-xia Guo, Zhen-Yu Yang, Xiang-Jun Yang and Wen-ping Jiang
    Citation: Lipids in Health and Disease 2010 9:39
    Content type: Research Published on:

  45. Dexamethasone (DEX) is known to induce diabetes and dyslipidemia. We have compared fasting triacylglycerol and cholesterol concentrations across 20 lipoprotein fractions and glucose tolerance in control (stand...

    Authors: Michaela Krupková, Lucie Šedová, František Liška, Drahomíra Křenová, Vladimír Křen and Ondřej Šeda
    Citation: Lipids in Health and Disease 2010 9:38
    Content type: Short paper Published on:

  46. Chicken meat with reduced concentration of arachidonic acid (AA) and reduced ratio between omega-6 and omega-3 fatty acids has potential health benefits because a reduction in AA intake dampens prostanoid signali...

    Authors: Anna Haug, Ingrid Olesen and Olav A Christophersen
    Citation: Lipids in Health and Disease 2010 9:37
    Content type: Research Published on:

  47. Adipocytes contribute to inflammation and the innate immune response through expression of inflammatory mediators. High levels of these mediators have been related to chronic inflammation state and insulin res...

    Authors: Aurelio Ocaña, Cristina Gómez-Asensio, Elena Arranz-Gutiérrez, Carlos Torres, Francisco Javier Señoráns and Guillermo Reglero
    Citation: Lipids in Health and Disease 2010 9:36
    Content type: Research Published on:

  48. Oxidative damage has been proposed as a possible mechanism involved in lead toxicity, specially affecting the liver and kidney. Previous studies have shown the antioxidant effect of Spirulina maxima in several ex...

    Authors: Johny C Ponce-Canchihuamán, Oscar Pérez-Méndez, Rolando Hernández-Muñoz, Patricia V Torres-Durán and Marco A Juárez-Oropeza
    Citation: Lipids in Health and Disease 2010 9:35
    Content type: Research Published on:

  49. Serum apolipoprotein (apo) A-I was considered to be an immune regulator and could suppress pro-inflammatory cytokines generated by activated T cell in some autoimmune diseases. However, the change of serum apo...

    Authors: Bin Zhang, ShuXiang Pu, BinMei Li, JianRui Ying, Xing Wang Song and Cong Gao
    Citation: Lipids in Health and Disease 2010 9:34
    Content type: Research Published on:

  50. Paraoxonase-1 (PON1) is an antioxidant enzyme that attenuates the production of the monocyte chemoattractant protein-1 (MCP-1) in vitro. Although oxidation and inflammation are closely related processes, the asso...

    Authors: Sandra Parra, Judit Marsillach, Gerard Aragonès, Anna Rull, Raúl Beltrán-Debón, Carlos Alonso-Villaverde, Jorge Joven and Jordi Camps
    Citation: Lipids in Health and Disease 2010 9:32
    Content type: Short paper Published on:
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Lipids in Health and Disease

ISSN: 1476-511X