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  1. Changes in immune function believed to contribute to a variety of age-related diseases have been associated with increased production of nitric oxide (NO). We have recently reported that proteasome inhibitors ...

    Authors: Asaf A Qureshi, Xiaoyu Tan, Julia C Reis, Mostafa Z Badr, Christopher J Papasian, David C Morrison and Nilofer Qureshi
    Citation: Lipids in Health and Disease 2011 10:239
  2. Brown adipose tissue (BAT) has thermogenic potential. For its activation, cold exposure is considered a critical factor though other determinants have also been reported. The purpose of this study was to asses...

    Authors: Yung-Cheng Huang, Tai-Been Chen, Chien-Chin Hsu, Shau-Hsuan Li, Pei-Wen Wang, Bi-Fang Lee, Ching-Yuan Kuo and Nan-Tsing Chiu
    Citation: Lipids in Health and Disease 2011 10:238
  3. The presence of smaller low-density lipoproteins (LDL) has been associated with atherosclerosis risk, and the insulin resistance (IR) underlying the metabolic syndrome (MetS). In addition, some research has su...

    Authors: Alexis C Frazier-Wood, Stephen Glasser, W Timothy Garvey, Edmond K Kabagambe, Ingrid B Borecki, Hemant K Tiwari, Michael Y Tsai, Paul N Hopkins, Jose M Ordovas and Donna K Arnett
    Citation: Lipids in Health and Disease 2011 10:237
  4. Thymoquinone (TQ), the major active component of the medicinal herb Nigella sativa Linn., has been described as a chemopreventive and chemotherapeutic compound.

    Authors: Gamal Badr, Mohamed Mohany and Faisal Abu-Tarboush
    Citation: Lipids in Health and Disease 2011 10:236
  5. Prolonged wound healing is a complication of diabetes that contributes to mortality. Impaired wound healing occurs as a consequence of excessive reactive oxygen species (ROS) production. Whey protein (WP) is a...

    Authors: Hossam Ebaid, Amir Salem, Abdalla Sayed and Ali Metwalli
    Citation: Lipids in Health and Disease 2011 10:235
  6. Nonalcoholic fatty liver disease (NAFLD) is one of the most frequent causes of abnormal liver function. Because fatty acids can damage biological membranes, fatty acid accumulation in the liver may be partiall...

    Authors: Xin Wang, Yuzhen Cao, Yunwei Fu, Guifang Guo and Xiuying Zhang
    Citation: Lipids in Health and Disease 2011 10:234
  7. Despite significant research efforts on cancer therapy, diagnostics and imaging, many challenges remain unsolved. There are many unknown details regarding the interaction of nanoparticles (NPs) and biological ...

    Authors: Mohamed Anwar K Abdelhalim
    Citation: Lipids in Health and Disease 2011 10:233
  8. The long-lasting and abundant blooming of Pelagia noctiluca in Tunisian coastal waters compromises both touristic and fishing activities and causes substantial economic losses. Determining their molecular mode of...

    Authors: Yosra Ayed, Manel Boussabbeh, Wiem Zakhama, Chayma Bouaziz, Salwa Abid and Hassen Bacha
    Citation: Lipids in Health and Disease 2011 10:232
  9. The kidneys are essential for the metabolism of vitamin A (retinol) and its transport proteins retinol-binding protein 4 (RBP4) and transthyretin. Little is known about changes in serum concentration after liv...

    Authors: Andrea Henze, Jens Raila, Caroline Kempf, Petra Reinke, Anett Sefrin, Uwe Querfeld and Florian J Schweigert
    Citation: Lipids in Health and Disease 2011 10:231
  10. The association of rs17321515 single nucleotide polymorphism (SNP) near TRIB1 gene and serum lipid profiles has never been studied in the Chinese population. Therefore, the present study was undertaken to dete...

    Authors: Lynn Htet Htet Aung, Rui-Xing Yin, Dong-Feng Wu, Qing Li, Ting-Ting Yan, Yi-Ming Wang, Hui Li, Dai-Xun Wei, Yuan-Lu Shi and De-Zhai Yang
    Citation: Lipids in Health and Disease 2011 10:230
  11. In obesity, phenotypic switches occur in macrophage populations such that the predominantly M2-polarised anti-inflammatory state seen in lean individuals changes to a predominantly M1-polarised pro-inflammator...

    Authors: Suleiman A Isa, José S Ruffino, Maninder Ahluwalia, Andrew W Thomas, Keith Morris and Richard Webb
    Citation: Lipids in Health and Disease 2011 10:229
  12. Docosahexaenoic acid (DHA) and DHA-containing ethanolamine plasmalogens (PlsEtn) are decreased in the brain, liver and the circulation in Alzheimer's disease. Decreased supply of plasmalogen precursors to the ...

    Authors: Paul L Wood, Tara Smith, Nina Lane, M Amin Khan, Greg Ehrmantraut and Dayan B Goodenowe
    Citation: Lipids in Health and Disease 2011 10:227
  13. diabetes is a serious health problem and a source of risk for numerous severe complications such as obesity and hypertension. Treatment of diabetes and its related diseases can be achieved by inhibiting key di...

    Authors: Khaled Hamden, Henda Keskes, Sahla Belhaj, Kais Mnafgui, Abdelfattah feki and Noureddine Allouche
    Citation: Lipids in Health and Disease 2011 10:226
  14. Endurance exercise is known to promote a substantial effect on the energy balance in rats and humans. However, little is known about the exact mechanisms for the appetite-suppressive effects of endurance exerc...

    Authors: Jiexiu Zhao, Ye Tian, Jincheng Xu, Dongsen Liu, Xiaofang Wang and Binxiu Zhao
    Citation: Lipids in Health and Disease 2011 10:225
  15. High-density lipoproteins (HDL) and their main apolipoprotein, apoA-I, exhibit anti-inflammatory properties. The development of peptides that mimic HDL apolipoproteins offers a promising strategy to reduce inf...

    Authors: Belinda A Di Bartolo, Laura Z Vanags, Joanne TM Tan, Shisan Bao, Kerry-Anne Rye, Philip J Barter and Christina A Bursill
    Citation: Lipids in Health and Disease 2011 10:224
  16. Evidence suggests that physical activity (PA) has a beneficial effect on high-density lipoprotein cholesterol (HDL) and triglycerides. However, observational studies show contrasting results for this associati...

    Authors: Jeroen SL de Munter, Irene G van Valkengoed, Karien Stronks and Charles Agyemang
    Citation: Lipids in Health and Disease 2011 10:223
  17. Synthetic activators of peroxisome proliferator-activated receptors (PPARs) stimulate cholesterol removal from macrophages through PPAR-dependent up-regulation of liver × receptor α (LXRα) and subsequent induc...

    Authors: Ines Kämmerer, Robert Ringseis, Ronald Biemann, Gaiping Wen and Klaus Eder
    Citation: Lipids in Health and Disease 2011 10:222
  18. Bacterial lipases received much attention for their substrate specificity and their ability to function in extreme environments (pH, temperature...). Many staphylococci produced lipases which were released int...

    Authors: Slim Cherif, Sami Mnif, Fatma Hadrich, Slim Abdelkafi and Sami Sayadi
    Citation: Lipids in Health and Disease 2011 10:221
  19. Aging and dyslipidemia are processes which can lead to deleterious consequences to renal function. Therefore, the aim of this study was to determine the effects of both hypercholesterolemia and aging on renal ...

    Authors: Camille M Balarini, Mariana ZT Oliveira, Thiago MC Pereira, Nyam F Silva, Elisardo C Vasquez, Silvana S Meyrelles and Agata L Gava
    Citation: Lipids in Health and Disease 2011 10:220
  20. Among the digestive enzymes, phospholipase A2 (PLA2) hydrolyzes the essential dietary phospholipids in marine fish and shellfish. However, we know little about the organs that produce PLA2, and the ontogeny of th...

    Authors: Zied Zarai, Nicholas Boulais, Pascale Marcorelles, Eric Gobin, Sofiane Bezzine, Hafedh Mejdoub and Youssef Gargouri
    Citation: Lipids in Health and Disease 2011 10:219
  21. Previous studies have demonstrated that long chain fatty acids influence fibroblast function at sub-lethal concentrations. This study is the first to assess the effects of oleic, linoleic or palmitic acids on ...

    Authors: Juliana Magdalon, Elaine Hatanaka, Talita Romanatto, Hosana G Rodrigues, Wilson MT Kuwabara, Caitriona Scaife, Philip Newsholme and Rui Curi
    Citation: Lipids in Health and Disease 2011 10:218
  22. Obese subjects with impaired glucose tolerance (IGT) are more susceptible than healthy individuals to oxidative stress and cardiovascular disease. This randomised controlled investigation was designed to test ...

    Authors: Andrea M McNeilly, Gareth W Davison, Marie H Murphy, Nida Nadeem, Tom Trinick, Ellie Duly, Anna Novials and Jane McEneny
    Citation: Lipids in Health and Disease 2011 10:217
  23. We investigated relationship of low levels of high density lipoprotein cholesterol (HDL-C), high levels of triglycerides, and renal function for the odds, prognosis and survival following acute coronary events...

    Authors: Kuo-Liong Chien, Hung-Ju Lin, Hsiu-Ching Hsu and Ming-Fong Chen
    Citation: Lipids in Health and Disease 2011 10:215
  24. To develop effective strategies in cancer chemoprevention, an increased understanding of endogenous biochemical mediators that block metastatic processes is critically needed. Dietary lipids and non-steroidal ...

    Authors: Paul L Wood, M Amin Khan, Tara Smith and Dayan B Goodenowe
    Citation: Lipids in Health and Disease 2011 10:214
  25. Platelet activating factor (PAF) has been proposed as a key factor and initial trigger in atherosclerosis. Recently, a modulation of PAF metabolism by bioactive food constituents has been suggested. In this st...

    Authors: Constantina Nasopoulou, Alexandros B Tsoupras, Haralabos C Karantonis, Constantinos A Demopoulos and Ioannis Zabetakis
    Citation: Lipids in Health and Disease 2011 10:213
  26. Since the early 1990s, several strains of genetically modified mice have been developed as models for experimental atherosclerosis. Among the available models, the apolipoprotein E-deficient (apoE-/-) mouse is of...

    Authors: Silvana S Meyrelles, Veronica A Peotta, Thiago MC Pereira and Elisardo C Vasquez
    Citation: Lipids in Health and Disease 2011 10:211
  27. Probucol is a unique hypolipidemic agent that decreases high density lipoprotein cholesterol (HDL-C). However, it is not definite that whether probucol hinders the progression of atherosclerosis by improving H...

    Authors: Jian-Kai Zhong, Zhi-Gang Guo, Chen Li, Zhen-Kun Wang, Wen-Yan Lai and Yan Tu
    Citation: Lipids in Health and Disease 2011 10:210
  28. Extracellular bacterial lipases received much attention for their substrate specificity and their ability to function under extreme environments (pH, temperature...). Many staphylococci produced lipases which ...

    Authors: Slim Cherif, Sami Mnif, Fatma Hadrich, Slim Abdelkafi and Sami Sayadi
    Citation: Lipids in Health and Disease 2011 10:209
  29. Liver dominates the production and secretion of apolipoprotein B (apoB) and evidence shows that liver malfunction induced by hepatitis B virus (HBV) infection could lead to apolipoprotein metabolism disorders....

    Authors: Fu-Bing Wang, Cheng-liang Zhu, Xinghui Liu and Guo-sheng Gao
    Citation: Lipids in Health and Disease 2011 10:207
  30. Apolipoprotein E (apoE) is a key component of the lipid metabolism. Polymorphisms at the apoE gene (APOE) have been associated with cardiovascular disease, lipid levels and lipid-lowering response to statins. We ...

    Authors: Alvaro Cerda, Fabiana DV Genvigir, Maria AV Willrich, Simone S Arazi, Marcia MS Bernik, Egidio L Dorea, Marcelo C Bertolami, Andre A Faludi, Mario H Hirata and Rosario DC Hirata
    Citation: Lipids in Health and Disease 2011 10:206
  31. This study evaluated the relationship between ulcerative colitis and obesity, which are both chronic diseases characterized by inflammation and increases in immune cells and pro-inflammatory cytokines.

    Authors: Lílian G Teixeira, Alda J Leonel, Edenil C Aguilar, Nathália V Batista, Andréa C Alves, Candido C Coimbra, Adaliene VM Ferreira, Ana Maria C de Faria, Denise C Cara and Jacqueline I Alvarez Leite
    Citation: Lipids in Health and Disease 2011 10:204
  32. Long and persistent uncontrolled diabetes tends to degenerate the immune system and leads to an increased incidence of infection. Whey proteins (WPs) enhance immunity during early life and have a protective ro...

    Authors: Gamal Badr, Mohamed Mohany and Ali Metwalli
    Citation: Lipids in Health and Disease 2011 10:203
  33. Nonalcoholic fatty liver disease (NAFLD) is emerging as the most common liver disease of industrialized countries. Thus, discovering food components that can ameliorate NAFLD is of interest. Lotus root, the ed...

    Authors: Yumi Tsuruta, Koji Nagao, Shunichi Kai, Keisuke Tsuge, Takashi Yoshimura, Kazuyoshi Koganemaru and Teruyoshi Yanagita
    Citation: Lipids in Health and Disease 2011 10:202
  34. One of the well-defined and characterized protein modifications usually produced by oxidation is carbonylation, an irreversible non-enzymatic modification of proteins. However, carbonyl groups can be introduce...

    Authors: Rafael Medina-Navarro, Renato Nieto-Aguilar and Cleto Alvares-Aguilar
    Citation: Lipids in Health and Disease 2011 10:201
  35. Several polymorphisms in the apolipoprotein C3 (APOC3) gene have been found association with hypertriglyceridemia(HTG), but the link with coronary heart disease(CHD) risk between ethnicities was still controve...

    Authors: Juan Yu, Jingjing Huang, Yan Liang, Baodong Qin, Su He, Jing Xiao, Huimin Wang and Renqian Zhong
    Citation: Lipids in Health and Disease 2011 10:200
  36. Apolipoprotein M (apoM) may have potential antiatherosclerotic properties. It has been reported that apoM expression could be regulated by many intracellar and extracellar factors. In the present study we furt...

    Authors: Chunhua Zhu, Dongmei Di, Xiaoying Zhang, Guanghua Luo, Zongchun Wang, Jiang Wei, Yuanping Shi, Maria Berggren-Söderlund, Peter Nilsson-Ehle and Ning Xu
    Citation: Lipids in Health and Disease 2011 10:199
  37. Obesity is characterized by increased cell death and inflammatory reactions in the adipose tissue. Here, we explored pathophysiological alterations taking place in the adipose tissue in long-standing obesity. ...

    Authors: Mehmet M Altintas, Maria A Rossetti, Behzad Nayer, Alvaro Puig, Patricia Zagallo, Luis M Ortega, Kevin B Johnson, George McNamara, Jochen Reiser, Armando J Mendez and Ali Nayer
    Citation: Lipids in Health and Disease 2011 10:198
  38. Hepatic lipase (HL), an enzyme present in the hepatic sinusoids, is responsible for the lipolysis of lipoproteins. Human HL contains four polymorphic sites: G-250A, T-710C, A-763G, and C-514T single-nucleotide...

    Authors: Alvaro Pulchinelli Jr, Ana Maria Massad Costa, Cristina V de Carvalho, Naiara Correa Nogueira de Souza, Mauro A Haidar, Adagmar Andriolo and Ismael DC Guerreiro da Silva
    Citation: Lipids in Health and Disease 2011 10:197
  39. One particularly exciting field of research involves the use of gold nanoparticles (GNPs) in the detection and treatment of cancer cells in the liver. The detection and treatment of cancer is an area in which ...

    Authors: Mohamed Anwar K Abdelhalim and Mohsen Mahmoud Mady
    Citation: Lipids in Health and Disease 2011 10:195
  40. Alterations of endocannabinoid system in adipose tissue play an important role in lipid regulation and metabolic dysfunction associated with obesity. The purpose of this study was to determine whether gene exp...

    Authors: Tongjian You, Beth L Disanzo, Xuewen Wang, Rongze Yang and Dawei Gong
    Citation: Lipids in Health and Disease 2011 10:194
  41. Obesity, insulin resistance and hyperandrogenism, crucial parameters of Polycystic ovary syndrome (PCOS) play significant pathophysiological roles in lipidemic aberrations associated within the syndrome. Parts...

    Authors: Muammer Karadeniz, Mehmet Erdoğan, Zengi Ayhan, Murat Yalcın, Murat Olukman, Sevki Cetinkalp, Gulinnaz E Alper, Zuhal Eroglu, Asli Tetik, Vildan Cetintas, Ahmet G Ozgen, Fusun Saygılı and Candeger Yılmaz
    Citation: Lipids in Health and Disease 2011 10:193
  42. To correlate lipid metabolism and autonomic dysfunction with anxious-depressive spectrum and eating disorders. To propose the lipid index (LI) as a new possible biomarker.

    Authors: Elisabetta Pistorio, Maria Luca, Antonina Luca, Vincenzo Messina and Carmela Calandra
    Citation: Lipids in Health and Disease 2011 10:192
  43. Blood viscosity appears to be independent predictor of stroke, carotid intima-media thickening, atherosclerosis and most cardiovascular diseases. In an attempt to understand the toxicity and the potential thre...

    Authors: Mohamed Anwar K Abdelhalim
    Citation: Lipids in Health and Disease 2011 10:191
  44. Hyperlipidemia associated with obesity is closely related to the development of atherosclerosis. Both n-3 polyunsaturated fatty acids (PUFAs) and long-chain monounsaturated fatty acids (MUFAs; i.e., C20:1 and ...

    Authors: Zhi-Hong Yang, Hiroko Miyahara, Jiro Takeo, Akimasa Hatanaka and Masashi Katayama
    Citation: Lipids in Health and Disease 2011 10:189

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