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  1. Conjugated linoleic acid (CLA) is known to affect the lipid metabolism in growing and lactating animals. However, potential effects on the metabolism of fat-soluble vitamins in lactating animals and co-occurri...

    Authors: Johanna O. Zeitz, Erika Most and Klaus Eder
    Citation: Lipids in Health and Disease 2016 15:102
    Content type: Research Published on:

  3. The pharmacological inhibitor of phosphodiesterase 5 (PDE5), sildenafil, is a promising candidate for antioxidant therapy that can result in cardiovascular protection. In addition to its known effects on the c...

    Authors: Franciane P. Bernardes, Alan T. Batista, Marcella L. Porto, Elisardo C. Vasquez, Bianca P. Campagnaro and Silvana S. Meyrelles
    Citation: Lipids in Health and Disease 2016 15:100
    Content type: Research Published on:

  4. Nuclear receptor subfamily 1, group H, member 3 (NR1H3, an alias for Liver X receptor α, LXRα) is a member of the LXR nuclear receptor super family and is an important regulator of lipid and fatty acid accumulati...

    Authors: Bo Zhang, Peng Shang, Yangzong Qiangba, Aishi Xu, Zhixiu Wang and Hao Zhang
    Citation: Lipids in Health and Disease 2016 15:99
    Content type: Research Published on:

  5. Current study was designed to investigate the effects of obstructive sleep apnea (OSA) combined dyslipidemia on the prevalence of atherosclerotic cardiovascular diseases (ASCVD).

    Authors: Zhiyong Cao, Ping Zhang, Zhiqing He, Jing Yang, Chun Liang, Yusheng Ren and Zonggui Wu
    Citation: Lipids in Health and Disease 2016 15:98
    Content type: Research Published on:

  6. Epidemiological studies have disclosed an independent effect of triglycerides on coronary heart disease despite achievement of low-density lipoprotein cholesterol goals with statin therapy. Arterial stiffness ...

    Authors: Xiaona Wang, Ping Ye, Ruihua Cao, Xu Yang, Wenkai Xiao, Yun Zhang, Yongyi Bai and Hongmei Wu
    Citation: Lipids in Health and Disease 2016 15:97
    Content type: Research Published on:

  7. There is little data on the metabolic effects of adipokines in sub-Saharan African populations. This study aimed to explore the potential relationship of leptin and adiponectin, with obesity, plasma lipids and...

    Authors: Clarisse Noël A. Ayina, Jean Jacques N. Noubiap, Laurent Serge Etoundi Ngoa, Philippe Boudou, Jean François Gautier, Michel Karngong Mengnjo, Jean Claude Mbanya and Eugene Sobngwi
    Citation: Lipids in Health and Disease 2016 15:96
    Content type: Research Published on:

  8. Robust associations between lipoprotein(a) [Lp(a)] and CVD outcomes among general populations have been published in previous studies. However, associations in high risk primary prevention and secondary preven...

    Authors: Carol A. Forbes, Ruben G. W. Quek, Sohan Deshpande, Gill Worthy, Robert Wolff, Lisa Stirk, Jos Kleijnen, Shravanthi R. Gandra, Stephen Djedjos and Nathan D. Wong
    Citation: Lipids in Health and Disease 2016 15:95
    Content type: Review Published on:

  9. Apolipoprotein E (APOE) plays a major role in lipid metabolism and inflammation. However, the association between APOE gene polymorphisms and serum triglyceride levels remains controversial. We tested the effects...

    Authors: Semon Wu, Lung-An Hsu, Ming-Sheng Teng, Jeng-Feng Lin, Hsin-Hua Chou, Ming-Cheng Lee, Yi-Ming Wu, Cheng-Wen Su and Yu-Lin Ko
    Citation: Lipids in Health and Disease 2016 15:94
    Content type: Research Published on:

  10. It has been shown that irisin levels are reduced in skeletal muscle and plasma of obese rats; however, the effect of exercise training on irisin level remains controversial. We aim to evaluate the association ...

    Authors: Yun Lu, Hongwei Li, Shi-Wei Shen, Zhen-Hai Shen, Ming Xu, Cheng-Jian Yang, Feng Li, Yin-Bo Feng, Jing-Ting Yun, Ling Wang and Hua-Jin Qi
    Citation: Lipids in Health and Disease 2016 15:93
    Content type: Research Published on:

  11. Obesity and low high-density lipoprotein-cholesterol (HDL-C) levels are associated with cardiovascular risk. Surprisingly, despite a greater prevalence of obesity and lower HDL concentrations than white women,...

    Authors: Nicholas J. Woudberg, Julia H. Goedecke, Dee Blackhurst, Miguel Frias, Richard James, Lionel H. Opie and Sandrine Lecour
    Citation: Lipids in Health and Disease 2016 15:92
    Content type: Research Published on:

  12. Hypoxia resulting from adipocyte expansion is considered the basis of the inflammatory milieu observed in Metabolic Syndrome. Nicotinic acid can act on adipocytes interfering on the inflammatory response. In t...

    Authors: Renata Nakamichi, Erika Prates Miranda, Sylvia Madeira de Vergueiro Lobo, Vivian Regina Tristão, Maria Aparecida Dalboni, Beata Marie Redublo Quinto and Marcelo Costa Batista
    Citation: Lipids in Health and Disease 2016 15:91
    Content type: Research Published on:

  13. The objective of this study was to investigate the effects of maternal high fat intake on intestinal development and transcriptional profile.

    Authors: Lianqiang Che, Peilin Liu, Zhengguo Yang, Long Che, Liang Hu, Linlin Qin, Ru Wang, Zhengfeng Fang, Yan Lin, Shengyu Xu, Bin Feng, Jian Li and De Wu
    Citation: Lipids in Health and Disease 2016 15:90
    Content type: Research Published on:

  14. The consumption of n-3 polyunsaturated fatty acids (PUFAs) is important to human health, especially in cases of cardiovascular disease. Although beneficial effects of n-3 PUFAs have been observed in a number of s...

    Authors: Xingxing Liu, Daxin Pang, Ting Yuan, Zhuang Li, Zhanjun Li, Mingjun Zhang, Wenzhi Ren, Hongsheng Ouyang and Xiaochun Tang
    Citation: Lipids in Health and Disease 2016 15:89
    Content type: Short report Published on:

  15. Familial chylomicronemia syndrome (FCS) is a rare autosomal recessive disease due mainly to inherited deficiencies in the proteins or enzymes involved in the clearance of triglycerides from circulation. It usu...

    Authors: Yonghong Zhang, Jing Zhou, Wenxin Zheng, Zhangzhang Lan, Zhiwei Huang, Qingnan Yang, Chengbo Liu, Rui Gao and Yongjun Zhang
    Citation: Lipids in Health and Disease 2016 15:88
    Content type: Short report Published on:

  16. Childhood dyslipidemia is a critical factor of lifelong health. Therefore, screening and controlling dyslipidemia from childhood is a practical healthy strategy. However, few studies have examined the performa...

    Authors: Wei Zheng, Ai Zhao, Yong Xue, Yingdong Zheng, Yun Chen, Zhishen Mu, Peiyu Wang and Yumei Zhang
    Citation: Lipids in Health and Disease 2016 15:87
    Content type: Research Published on:

    The Erratum to this article has been published in Lipids in Health and Disease 2016 15:128

  17. Deep frying in oil is a popular cooking method around the world. However, the safety of deep-fried edible oil, which is ingested with fried food, is a concern, because the oil is exposed continuously to be re-...

    Authors: Zhongkai Zhou, Yuyang Wang, Yumei Jiang, Yongjia Diao, Padraig Strappe, Paul Prenzler, Jamie Ayton and Chris Blanchard
    Citation: Lipids in Health and Disease 2016 15:86
    Content type: Research Published on:

  18. Metabolic syndrome is closely associated with an increased risk for fatty liver disease morbidity and mortality. Recently, studies have reported that participants with fatty liver disease have higher serum alp...

    Authors: Yimin Chen, Ying Zhao, Linmin Feng, Jie Zhang, Juanwen Zhang and Guofang Feng
    Citation: Lipids in Health and Disease 2016 15:85
    Content type: Research Published on:

  19. The purpose of this analysis was to investigate the relationship between body composition, metabolic parameters and endothelial function among physically active healthy middle-aged and older men.

    Authors: Małgorzata Pigłowska, Tomasz Kostka, Wojciech Drygas, Anna Jegier, Joanna Leszczyńska, Mirosława Bill-Bielecka and Magdalena Kwaśniewska
    Citation: Lipids in Health and Disease 2016 15:84
    Content type: Research Published on:

  20. Many SNPs have been identified in genes regulating LDL-C metabolism, but whether their influence is similar in subjects from different ethnicities is unclear. Effect of 4 such SNPs on LDL-C and coronary heart ...

    Authors: Saleem Ullah Shahid, Shabana ᅟ, Jackie A. Cooper, Katherine E. Beaney, Kawah Li, Abdul Rehman and Stephen Eric Humphries
    Citation: Lipids in Health and Disease 2016 15:83
    Content type: Research Published on:

  21. Hypertriglyceridemia (HTG) is a common complex metabolic trait that results of the accumulation of relatively common genetic variants in combination with other modifier genes and environmental factors resultin...

    Authors: Itziar Lamiquiz-Moneo, Cristian Blanco-Torrecilla, Ana M. Bea, Rocío Mateo-Gallego, Sofía Pérez-Calahorra, Lucía Baila-Rueda, Ana Cenarro, Fernando Civeira and Isabel de Castro-Orós
    Citation: Lipids in Health and Disease 2016 15:82
    Content type: Research Published on:

  22. n-3 polyunsaturated fatty acids (PUFA) have previously been demonstrated in association with a reduced risk of chronic diseases, including insulin resistance, cancer and cardiovascular disease. In the present ...

    Authors: Xianxing Xie, Tao Zhang, Shuang Zhao, Wei Li, Lanzhi Ma, Ming Ding and Yuan Liu
    Citation: Lipids in Health and Disease 2016 15:81
    Content type: Research Published on:

  23. Abnormal serum lipid levels have been shown to be associated with the occurrence of atherosclerosis, but little is known about the relationships of them with the risk of developing intervertebral disc degenera...

    Authors: Yuedong Zhang, Yunpeng Zhao, Mei Wang, Meng Si, Jingkun Li, Yong Hou, Jialin Jia and Lin Nie
    Citation: Lipids in Health and Disease 2016 15:80
    Content type: Research Published on:

  24. Adhesion molecules are involved in the development of atherosclerosis. An increased level of the ICAM 1 molecule is associated with numerous inflammatory diseases including atherosclerosis of carotid arteries....

    Authors: Dražen Popović, Jovana Nikolajević Starčević, Marija Šantl Letonja, Jana Makuc, Andreja Cokan Vujkovac, Ruda Zorc Pleskovič, Ludovit Gaspar, Peter Kruzliak and Danijel Petrovič
    Citation: Lipids in Health and Disease 2016 15:79
    Content type: Research Published on:

  25. Nutrition therapy is the cornerstone of treating diabetes mellitus. The inclusion of fish (particularly oily fish) at least two times per week is recommended by current international dietary guidelines for typ...

    Authors: Mariona Balfegó, Silvia Canivell, Felicia A. Hanzu, Aleix Sala-Vila, Margarita Martínez-Medina, Serafín Murillo, Teresa Mur, Elena G. Ruano, Francisca Linares, Nuria Porras, Silvia Valladares, Maria Fontalba, Elena Roura, Anna Novials, Cristina Hernández, Gloria Aranda…
    Citation: Lipids in Health and Disease 2016 15:78
    Content type: Research Published on:

  26. The article by Aiso et al. titled “Compared with the intake of commercial vegetable juice, the intake of fresh fruit and komatsuna (Brassica rapa L. var perviridis) juice mixture reduces serum cholesterol in midd...

    Authors: David B. Allison, Lisa H. Antoine and Brandon J. George
    Citation: Lipids in Health and Disease 2016 15:77
    Content type: Commentary Published on:

    The original article was published in Lipids in Health and Disease 2014 13:102

  27. Diabetic nephropathy has a high cardiovascular risk with a low-level HDL(high density lipoprotein) in epidemiologic studies. Glycated HDL in diabetes can diminish the capacity to stimulate endothelial cell mig...

    Authors: Yufeng Li, Mingming Zhao, Dan He, Xuyang Zhao, Wenjing Zhang, Lixin Wei, Edgar Huang, Liang Ji, Meng Zhang, Belinda Willard, Zuodi Fu, Lijuan Wang, Bing Pan, Lemin Zheng and Linong Ji
    Citation: Lipids in Health and Disease 2016 15:76
    Content type: Research Published on:

  28. The deleterious effects of dietary trans fatty acids (tFAs) on human health are well documented. Although significantly reduced or banned in various countries, tFAs may trigger long-term responses that would repr...

    Authors: José Flores-Sierra, Martín Arredondo-Guerrero, Braulio Cervantes-Paz, Dalia Rodríguez-Ríos, Yolanda Alvarado-Caudillo, Finn C. Nielsen, Katarzyna Wrobel, Kazimierz Wrobel, Silvio Zaina and Gertrud Lund
    Citation: Lipids in Health and Disease 2016 15:75
    Content type: Research Published on:

  29. Plasma lipid profiling has emerged as a useful tool for understanding the pathophysiology of hepatic injury and disease. Hepatic fibrosis results from chronic, progressive damage to the liver and can lead, in ...

    Authors: Masaki Ishikawa, Kosuke Saito, Hiroshi Yamada, Noriyuki Nakatsu, Keiko Maekawa and Yoshiro Saito
    Citation: Lipids in Health and Disease 2016 15:74
    Content type: Research Published on:

  30. Increasing natural drug demand for pharmaceutical uses has encouraged scientifics all over the world to explore medicinal plants recognized as efficient remedies. In this context, extracted oil from pumpkin se...

    Authors: Sana Bardaa, Nihed Ben Halima, Fatma Aloui, Riadh Ben Mansour, Hazem Jabeur, Mohamed Bouaziz and Zouheir Sahnoun
    Citation: Lipids in Health and Disease 2016 15:73
    Content type: Research Published on:

  31. In animal models, secreted frizzled related protein 1 (Sfrp1) inhibition of the Wnt signaling pathway is beneficial because Sfrp1 reduces myocardial apoptosis and prevents heart failure. The mechanisms mediati...

    Authors: Jing Tao, Mayila Abudoukelimu, Yi-tong Ma, Yi-ning Yang, Xiao-mei Li, Bang-dang Chen, Fen Liu, Chun-hui He and Hua-yin Li
    Citation: Lipids in Health and Disease 2016 15:72
    Content type: Research Published on:

  32. Long-chain polyunsaturated fatty acids (PUFAs) are major components of the phospholipids that forming the cell membrane. Insufficient availability of PUFAs during prenatal period decreases accretion of docosah...

    Authors: Mimi Tang, Min Zhang, Hualin Cai, Huande Li, Pei Jiang, Ruili Dang, Yiping Liu, Xin He, Ying Xue, Lingjuan Cao and Yanqin Wu
    Citation: Lipids in Health and Disease 2016 15:71
    Content type: Research Published on:

  33. This study investigated associations between type 2 diabetes mellitus and non-traditional lipid measures (total cholesterol (TC)/high-density lipoprotein cholesterol (HDL-C), triglycerides (TG)/HDL-C, and non-...

    Authors: Qiaofeng Song, Xiaoxue Liu, Anxin Wang, Youxin Wang, Yong Zhou, Wenhua Zhou and Xizhu Wang
    Citation: Lipids in Health and Disease 2016 15:70
    Content type: Research Published on:

  34. Uncontrolled inflammation participates in the development of inflammatory diseases. Beneficial effects of polyunsaturated fatty acids belonging to the n-3 family such as eicosapentaenoic acid (EPA) and docosah...

    Authors: Bénédicte Allam-Ndoul, Frédéric Guénard, Olivier Barbier and Marie-Claude Vohl
    Citation: Lipids in Health and Disease 2016 15:69
    Content type: Research Published on:

  36. Detection of type 2 diabetes (T2D) is routinely based on the presence of dysglycemia. Although disturbed lipid metabolism is a hallmark of T2D, the potential of plasma lipidomics as a biomarker of future T2D i...

    Authors: Manju Mamtani, Hemant Kulkarni, Gerard Wong, Jacquelyn M. Weir, Christopher K. Barlow, Thomas D. Dyer, Laura Almasy, Michael C. Mahaney, Anthony G. Comuzzie, David C. Glahn, Dianna J. Magliano, Paul Zimmet, Jonathan Shaw, Sarah Williams-Blangero, Ravindranath Duggirala, John Blangero…
    Citation: Lipids in Health and Disease 2016 15:67
    Content type: Research Published on:

  37. This study was performed to compare the effects of three different lipid-lowering therapies (statins, ezetimibe, and colestimide) on lipoprotein lipase and endothelial lipase masses in pre-heparin plasma (pre-...

    Authors: Hayato Tada, Junji Kobayashi, Masa-aki Kawashiri, Kazuya Miyashita, Atsushi Nohara, Akihiro Inazu, Katsuyuki Nakajima, Hiroshi Mabuchi and Masakazu Yamagishi
    Citation: Lipids in Health and Disease 2016 15:66
    Content type: Research Published on:

  38. The aim of this study was to evaluate the protective effects of subacute pre-treatment with chamomile (Matricaria recutita L.) decoction extract (CDE) against stimulated neutrophils ROS production as well as etha...

    Authors: Mohamed-Amine Jabri, Mamane Sani, Kais Rtibi, Lamjed Marzouki, Jamel El-Benna, Mohsen Sakly and Hichem Sebai
    Citation: Lipids in Health and Disease 2016 15:65
    Content type: Research Published on:

  39. Hepatitis B virus (HBV) infection correlated with the development of cirrhosis, liver failure and hepatocellular carcinoma (HCC), poses a huge health burden on the global community. However, the pathogenesis o...

    Authors: Yuanyuan Wang, Junli Hao, Xiaohong Liu, Hongxin Wang, Xin Zeng, Jing Yang, Lei Li, Xi Kuang and Tao Zhang
    Citation: Lipids in Health and Disease 2016 15:64
    Content type: Research Published on:

  40. Angiopoietin-like protein 4 (ANGPTL4) is a metabolic factor that increases plasma triglyceride levels by inhibiting lipoprotein lipase (LPL). The objective of this study was to investigate the association of A...

    Authors: Kaouthar Abid, Thouraya Trimeche, Donia Mili, Mohamed Amine Msolli, Imen Trabelsi, Semir Nouira and Abderraouf Kenani
    Citation: Lipids in Health and Disease 2016 15:63
    Content type: Research Published on:

  42. Omega3 polyunsaturated fatty acids (PUFAs) are related to several diseases, including smoking. The aim of this study was to evaluate the relationship between omega-3 intake and tobacco smoking, taking into acc...

    Authors: Nóris Scaglia, José Chatkin, Kenneth R. Chapman, Ivone Ferreira, Mario Wagner, Peter Selby, Johane Allard and Noe Zamel
    Citation: Lipids in Health and Disease 2016 15:61
    Content type: Research Published on:

  43. The causes of increased cardiovascular risk in systemic lupus erythematosus (SLE) are not understood thoroughly, although presence of traditional cardiovascular risk factors and disease-specific agents were al...

    Authors: Krisztina Gaál, Tünde Tarr, Hajnalka Lőrincz, Viktor Borbás, Ildikó Seres, Mariann Harangi, Péter Fülöp and György Paragh
    Citation: Lipids in Health and Disease 2016 15:60
    Content type: Research Published on:

  44. Recently, variations in a component of high-density lipoprotein (HDL), namely apolipoprotein M (apoM), were found to be associated with chronic obstructive pulmonary disease (COPD). The aim of this study was t...

    Authors: Hui Li, Yinyin Liu, Ling Wang, Ting Shen, Wenhan Du, Zhijun Liu, Ruohong Chen and Min Hu
    Citation: Lipids in Health and Disease 2016 15:59
    Content type: Research Published on:

  45. Epidemiological studies have assessed relationships between circulating levels of fatty acid (FA) and blood pressure (BP), and their results remain controversial. Nevertheless, data are sparse on serum FA as b...

    Authors: Bo Yang, Fang Ding, Jing Yan, Xiong-Wei Ye, Xiao-Lin Xu, Feng-Lei Wang, Duo Li and Wei Yu
    Citation: Lipids in Health and Disease 2016 15:58
    Content type: Research Published on:

  46. Statins decrease cholesteryl ester transfer protein (CETP) levels, which have been positively associated with hepatic lipid content as well as serum low density lipoproteins-cholesterol (LDL-C) levels. However...

    Authors: Akihiro Shimada, Hideki Kimura, Koji Oida, Hideo Kanehara, Yukihiro Bando, Shinobu Sakamoto, Takanobu Wakasugi, Takashi Saga, Yasuki Ito, Kazuko Kamiyama, Daisuke Mikami, Masayuki Iwano, Tsutomu Hirano and Haruyoshi Yoshida
    Citation: Lipids in Health and Disease 2016 15:57
    Content type: Research Published on:

  47. High-Density Lipoprotein (HDL)-cholesterol, has been associated with breast cancer development, but the association is under debate, and whether lipoprotein subfractions is associated with breast tumor charact...

    Authors: Vidar G. Flote, Riyas Vettukattil, Tone F. Bathen, Thore Egeland, Anne McTiernan, Hanne Frydenberg, Anders Husøy, Sissi E. Finstad, Jon Lømo, Øystein Garred, Ellen Schlichting, Erik A. Wist and Inger Thune
    Citation: Lipids in Health and Disease 2016 15:56
    Content type: Research Published on:

  48. LDL cholesterol (LDLC) lowering has been revolutionized by PCSK9 inhibitors, Alirocumab (Praluent) and Evolocumab (Repatha), approved as adjuncts to maximally tolerated cholesterol lowering therapy in heterozy...

    Authors: Charles J. Glueck, Parth Shah, Naila Goldenberg, Marloe Prince, Kevin Lee, Vybhav Jetty, Ashwin Kumar, Michael Goldenberg and Ping Wang
    Citation: Lipids in Health and Disease 2016 15:55
    Content type: Research Published on:

  49. Irisin is a recently identified myokine that plays an important role in preventing obesity and insulin resistance. We investigated whether the common FNDC5 (irisin precursor) gene variants influence susceptibi...

    Authors: Nasser M. Al-Daghri, Abdul Khader Mohammed, Omar S. Al-Attas, Osama E. Amer, Mario Clerici, Amal Alenad and Majed S. Alokail
    Citation: Lipids in Health and Disease 2016 15:54
    Content type: Research Published on:

  50. Non-alcoholic fatty liver disease (NAFLD) is a common chronic liver disease which represents a wide spectrum of hepatic damage. Several studies have reported that NAFLD is a strong independent risk factor for ...

    Authors: Xiao-Lin Li, Jian-Qing Sui, Lin-Lin Lu, Nan-Nan Zhang, Xin Xu, Quan-Yong Dong, Yong-Ning Xin and Shi-Ying Xuan
    Citation: Lipids in Health and Disease 2016 15:53
    Content type: Review Published on:
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Lipids in Health and Disease

ISSN: 1476-511X